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Drug Discovery Today
Volumn 9, Issue 17, 2004, Pages 727-729
Molecular genetics: The Emperor's clothes of drug discovery?
Author keywords

Anticytokines; Cell biology; Deductive pharmacology; Drug Discovery; Failures of molecular genetics; Genetic engineering; Genetics; Pharmaceutical research; Pharmaceutical Science
Indexed keywords

ACETYLSALICYLIC ACID; BUDESONIDE; CIMETIDINE; CYTOKINE ANTIBODY; FLUTICASONE; IBUPROFEN; INFLIXIMAB; TUMOR NECROSIS FACTOR ANTIBODY;
EID: 4344639035     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(04)03143-5     Document Type: Editorial
Times cited : (11)
References (9)
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  • 3
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    • Watson, J.D.1    Crick, F.H.C.2
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    • The error of determination of toxicity
    • Trevan J.W. The error of determination of toxicity. Proc. R. Soc. 101B:1927;483-514
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    • Trevan, J.W.1
  • 5
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    • Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis
    • Brennan F.M., et al. Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis. Lancet. 2:1989;244-247
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  • 6
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    • The effect of monoclonal antibodies to tumour necrosis factor in animal models of chronic arthritis
    • Henderson B., et al. The effect of monoclonal antibodies to tumour necrosis factor in animal models of chronic arthritis. Br. J. Pharmacol. 104:1991;442P
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    • Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis
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  • 8
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    • The effect of synovial tissue on the breakdown of articular cartilage in organ culture
    • Fell H.B., Jubb R.W. The effect of synovial tissue on the breakdown of articular cartilage in organ culture. Arthritis. Rheum. 20:1977;1359-1371
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    • Continuous cultures of fused cells secreting antibody of predefined specificity
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.