Glucose metabolism and energy homeostasis in mouse hearts overexpressing dominant negative α2 subunit of AMP-activated protein kinase

Journal of Biological Chemistry

Volumn 278, Issue 31, 2003, Pages 28372-28377

  Xing, Yanqiu ^a   Musi, Nicolas ^a   Fujii, Nobuharu ^a   Zou, Liqun ^a   Luptak, Ivan ^a   Hirshman, Michael F ^a   Goodyear, Laurie J ^a   Tian, Rong ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b NMR Lab for Physiological Chemistry   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSTS; ENZYMES; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ENERGY HOMEOSTASIS;

GLUCOSE;

ADENOSINE MONOPHOSPHATE ACTIVATED PROTEIN KINASE ALPHA2; ADENOSINE TRIPHOSPHATE; DEOXYGLUCOSE; GLUCOSE; PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENERGY METABOLISM; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME SUBUNIT; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE ISCHEMIA; HOMEOSTASIS; ISOLATED HEART; MOUSE; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRESS; TRANSGENIC MOUSE;

ADENOSINE TRIPHOSPHATE; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGLUCOSE; ENERGY METABOLISM; GLUCOSE; GLYCOGEN; GLYCOLYSIS; HOMEOSTASIS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, TRANSGENIC; MULTIENZYME COMPLEXES; MYOCARDIAL ISCHEMIA; MYOCARDIUM; PHOSPHATES; PROTEIN-SERINE-THREONINE KINASES;

ANIMALIA; MUS MUSCULUS;

EID: 0041707843     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M303521200     Document Type: Article

References (34)

1. Hardie, D. G., Carling, D., and Carlson, M. (1998) Annu. Rev. Biochem. 67, 821-855
2. Hardie, D. G., and Carling, D. (1997) Eur. J. Biochem. 246, 259-273
3. Kemp, B. E., Mitchelhill, K. I., Stapleton, D., Michell, B. J., Chen, Z. P., and Witters, L. A. (1999) Trends Biochem. Sci. 24, 22-25
4. Stapleton, D., Woollatt, E., Mitchelhill, K. I., Nicholl, J. K., Fernandez, C. S., Michell, B. J., Witters, L. A., Power, D. A., Sutherland, G. R., and Kemp, B. E. (1997) FEBS Lett. 409, 452-456
5. Stapleton, D., Mitchelhill, K. I., Gao, G., Widmer, J., Michell, B. J., Teh, T., House, C. M., Fernandez, C. S., Cox, T., Witters, L. A., and Kemp, B. E. (1996) J. Biol. Chem. 271, 611-614
6. Winder, W. W., and Hardie, D. G. (1999) Am. J. Physiol. 277, E1-E10
7. Ruderman, N. B., Saha, A. K., Vavvas, D., and Witters, L. A. (1999) Am. J. Physiol. 276, E1-E18
8. Hayashi, T., Hirshman, M. F., Fujii, N., Habinowski, S. A., Witters, L. A., and Goodyear, L. J. (2000) Diabetes 49, 527-531
9. Fujii, N., Hayashi, T., Hirshman, M. F., Smith, J. T., Habinowski, S. A., Kaijser, L., Mu, J., Ljungqvist, O., Birnbaum, M. J., Witters, L. A., Thorell, A., and Goodyear, L. J. (2000) Biochem. Biophys. Res. Commun. 273, 1150-1155
10. Marsin, A. S., Bertrand, L., Rider, M. H., Deprez, J., Beauloye, C., Vincent, M. F., Van den Berghe, G., Carling, D., and Hue, L. (2000) Curr. Biol. 10, 1247-1255
11. Tian, R., Musi, N., D'Agostino, J., Hirshman, M. F., and Goodyear, L. J. (2001) Circulation 104, 1664-1669
12. Kudo, N., Gillespie, J. G., Kung, L., Witters, L. A., Schulz, R., Clanachan, A. S., and Lopaschuk, G. D. (1996) Biochim. Biophys. Acta 1301, 67-75
13. Russell, R. R., 3rd, Bergeron, R., Shulman, G. I., and Young, L. H. (1999) Am. J. Physiol. 277, H643-H649
14. Stein, S. C., Woods, A., Jones, N. A., Davison, M. D., and Carling, D. (2000) Biochem. J. 345, 437-443
15. Woods, A., Azzout-Marniche, D., Foretz, M., Stein, S., Lemarchand, P., Ferre, P., Foufelle, F., and Carling, D. (2000) Mol. Cell. Biol. 20, 6704-6711
16. Tian, R., and Abel, E. D. (2001) Circulation 103, 2961-2966
17. Abel, E. D., Kaulbach, H. C., Tian, R., Hopkins, J. C., Duffy, J., Doetschman, T., Minnemann, T., Boers, M. E., Hadro, E., Oberste-Berghaus, C., Quist, W., Lowell, B. B., Ingwall, J. S., and Kahn, B. B. (1999) J. Clin. Invest. 104, 1703-1714
18. Musi, N., Fujii, N., Hirshman, M. F., Ekberg, I., Froberg, S., Ljungqvist, O., Thorell, A., and Goodyear, L. J. (2001) Diabetes 50, 921-927
19. Davies, S. P., Carling, D., and Hardie, D. G. (1989) Eur. J. Biochem. 186, 123-128
20. Bak, M. I., and Ingwall, J. S. (1994) J. Clin. Invest. 93, 40-49
21. Passonneau, J. V., and Lauderdale, V. R. (1974) Anal. Biochem. 60, 405-412
22. Polimeni, P. I., and Buraczewski, S. I. (1988) J. Mol. Cell. Cardiol. 20, 15-22
23. Crute, B. E., Seefeld, K., Gamble, J., Kemp, B. E., and Witters, L. A. (1998) J. Biol. Chem. 273, 35347-35354
24. Mu, J., Brozinick, J. T., Jr., Valladares, O., Bucan, M., and Birnbaum, M. J. (2001) Mol. Cell 7, 1085-1094
25. Bergeron, R., Russell, R. R., 3rd, Young, L. H., Ren, J. M., Marcucci, M., Lee, A., and Shulman, G. I. (1999) Am. J Physiol. 276, E938-E944
26. Hayashi, T., Hirshman, M. F., Kurth, E. J., Winder, W. W., and Goodyear, L. J. (1998) Diabetes 47, 1369-1373
27. Tong, H., Chen, W., London, R. E., Murphy, E., and Steenbergen, C. (2000) J. Biol. Chem. 275, 11981-11986
28. Russell, R. R., 3rd, Yin, R., Caplan, M. J., Hu, X., Ren, J., Shulman, G. I., Sinusas, A. J., and Young, L. H. (1998) Circulation 98, 2180-2186
29. Egert, S., Nguyen, N., and Schwaiger, M. (1999) Circ. Res. 84, 1407-1415
30. Depre, C., Rider, M. H., and Hue, L. (1998) Eur. J Biochem. 258, 277-290
31. Uyeda, K. (1979) Adv. Enzymol. Relat. Areas Mol. Biol. 48, 193-244
32. Opie, L. H. (1998) The Heart: Physiology, from Cell to Circulation, 3rd Ed., pp. 295-342, Lippincott-Raven Publishers, Philadelphia
33. Gibbs, C. L., Papadoyannis, D. E., Drake, A. J., and Noble, M. I. (1980) Circ. Res. 47, 408-417
34. Suga, H. (1990) Physiol. Rev. 70, 247-277