Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction

Journal of Biological Chemistry

Volumn 284, Issue 51, 2009, Pages 35839-35849

  Ikeda, Yasumasa ^a   Sato, Kaori ^a   Pimentel, David R ^a   Sam, Flora ^a   Shaw, Reuben J ^b   Dyck, Jason R B ^c   Walsh, Kenneth ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMP-ACTIVATED PROTEIN KINASE; ATRIAL FIBRILLATION; CAPILLARY DENSITY; CARDIAC HYPERTROPHY; CARDIAC MYOCYTES; COLLAGEN I; CONSTITUTIVELY ACTIVES; KNOCK OUTS; LEFT VENTRICULAR HYPERTROPHIES; MAMMALIAN TARGET OF RAPAMYCIN (MTOR); MRNA EXPRESSION; MYOSIN HEAVY CHAIN; PROTEIN LEVEL; RAPAMYCIN; VASCULAR ENDOTHELIAL GROWTH FACTOR;

ANTIBIOTICS; BIOACTIVITY; ENZYME ACTIVITY; MAMMALS; PEPTIDES; PHOSPHORYLATION; SELF ASSEMBLY; SIGNALING;

PATHOLOGY;

COLLAGEN TYPE 1; COLLAGEN TYPE 2; ELONGATION FACTOR 2; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MESSENGER RNA; MYOSIN HEAVY CHAIN ALPHA; PROTEIN KINASE LKB1; S6 KINASE; VASCULOTROPIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CAPILLARY DENSITY; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE DELETION; GENE EXPRESSION; GENE SILENCING; HEART ATRIUM; HEART ATRIUM FIBRILLATION; HEART FAILURE; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE FIBROSIS; HEART VENTRICLE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ATRIAL FIBRILLATION; CARRIER PROTEINS; COLLAGEN TYPE I; COLLAGEN TYPE II; FIBROSIS; GENE EXPRESSION REGULATION; HEART ATRIA; HYPERTROPHY, LEFT VENTRICULAR; MICE; MICE, KNOCKOUT; MYOCARDIUM; ORGAN SPECIFICITY; PEPTIDE ELONGATION FACTOR 2; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RNA, MESSENGER; SIGNAL TRANSDUCTION; SIROLIMUS;

MAMMALIA; MUS;

EID: 72149093508     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.057273     Document Type: Article

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