메뉴 건너뛰기




Volumn 58, Issue 11, 2009, Pages 2536-2546

Nutrient stress activates inflammation and reduces glucose metabolism by suppressing AMP-activated protein kinase in the heart

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INTERLEUKIN 6;

EID: 70350560556     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db08-1361     Document Type: Article
Times cited : (135)

References (46)
  • 2
    • 85047677635 scopus 로고
    • The diabetic heart: Metabolic causes for the development of a cardiomyopathy
    • Rodrigues B, McNeill JH. The diabetic heart: metabolic causes for the development of a cardiomyopathy. Cardiovascular Res 1992;26:913-922
    • (1992) Cardiovascular Res , vol.26 , pp. 913-922
    • Rodrigues, B.1    McNeill, J.H.2
  • 3
    • 0021945547 scopus 로고
    • Defective energy metabolism of the heart in diabetes
    • Taegtmeyer H, Passmore JM. Defective energy metabolism of the heart in diabetes. Lancet 1985;1:139-141
    • (1985) Lancet , vol.1 , pp. 139-141
    • Taegtmeyer, H.1    Passmore, J.M.2
  • 4
    • 0030815973 scopus 로고    scopus 로고
    • Molecular analysis of insulin resistance in isolated ventricular cardiomyocytes of obese Zucker rats
    • Kolter T, Uphues I, Eckel J. Molecular analysis of insulin resistance in isolated ventricular cardiomyocytes of obese Zucker rats. Am J Physiol 1997;273:E59-E67
    • (1997) Am J Physiol , vol.273
    • Kolter, T.1    Uphues, I.2    Eckel, J.3
  • 5
    • 0028960273 scopus 로고
    • Myocardial glucose metabolism in noninsulin-dependent diabetes mellitus patients evaluated by FDG-PET
    • Ohtake T, Yokoyama I, Watanabe Y, Momose T, Serezawa T, Nishikawa J, Sasaki Y. Myocardial glucose metabolism in noninsulin-dependent diabetes mellitus patients evaluated by FDG-PET. J Nucl Med 1995;36:456-463
    • (1995) J Nucl Med , vol.36 , pp. 456-463
    • Ohtake, T.1    Yokoyama, I.2    Watanabe, Y.3    Momose, T.4    Serezawa, T.5    Nishikawa, J.6    Sasaki, Y.7
  • 6
    • 0030017114 scopus 로고    scopus 로고
    • Abnormal mechanical function in diabetes: Relationship to altered myocardial carbohydrates/lipid metabolism
    • Lopaschuk GD. Abnormal mechanical function in diabetes: relationship to altered myocardial carbohydrates/lipid metabolism. Coronary Artery Dis 1996;7:116-123
    • (1996) Coronary Artery Dis , vol.7 , pp. 116-123
    • Lopaschuk, G.D.1
  • 8
    • 33646756219 scopus 로고    scopus 로고
    • Cellular inflammatory responses: Novel insights for obesity and insulin resistance
    • DOI 10.1016/j.phrs.2006.03.003, PII S1043661806000405
    • Chen H. Cellular inflammatory responses: novel insights for obesity and insulin resistance. Pharmacological Res 2006;53:469-477 (Pubitemid 43767552)
    • (2006) Pharmacological Research , vol.53 , Issue.6 , pp. 469-477
    • Chen, H.1
  • 11
    • 33846004396 scopus 로고    scopus 로고
    • Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins
    • Lumeng CN, Deyoung SM, Saltiel AR. Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins. Am J Physiol 2007;292:E166-E174
    • (2007) Am J Physiol , vol.292
    • Lumeng, C.N.1    Deyoung, S.M.2    Saltiel, A.R.3
  • 12
    • 31444452629 scopus 로고    scopus 로고
    • Macrophage-secreted factors induce adipocyte inflammation and insulin resistance
    • Permana PA, Menge C, Reaven PD. Macrophage-secreted factors induce adipocyte inflammation and insulin resistance. Biochem Biophys Res Comm 2006;341:507-514
    • (2006) Biochem Biophys Res Comm , vol.341 , pp. 507-514
    • Permana, P.A.1    Menge, C.2    Reaven, P.D.3
  • 14
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993;259:87-91 (Pubitemid 23036092)
    • (1993) Science , vol.259 , Issue.5091 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 16
    • 0035023128 scopus 로고    scopus 로고
    • Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance
    • Kern PA, Ranganathan S, Li C, Wood L, Ranganathan G. Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance. Am J Physiol 2001;280:E745-E751 (Pubitemid 33774944)
    • (2001) American Journal of Physiology , vol.280 , Issue.5 PART 1
    • Kern, P.A.1    Ranganathan, S.2    Li, C.3    Wood, L.4    Ranganathan, G.5
  • 17
    • 0036894360 scopus 로고    scopus 로고
    • Interleukin-6 induces cellular insulin resistance in hepatocytes
    • Senn JJ, Klover PJ, Nowak IA, Mooney RA. Interleukin-6 induces cellular insulin resistance in hepatocytes. Diabetes 2002;51:3391-3399 (Pubitemid 35403441)
    • (2002) Diabetes , vol.51 , Issue.12 , pp. 3391-3399
    • Senn, J.J.1    Klover, P.J.2    Nowak, I.A.3    Mooney, R.A.4
  • 18
    • 4544256147 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling
    • DOI 10.1074/jbc.M403886200
    • Shi H, Tzameli I, Bjorbaek C, Flier JS. Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling. J Biol Chem 2004;279:34733-34740 (Pubitemid 39318104)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.33 , pp. 34733-34740
    • Shi, H.1    Tzameli, I.2    Bjorbaek, C.3    Flier, J.S.4
  • 19
    • 33846883060 scopus 로고    scopus 로고
    • Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis
    • Pedersen BK, Febbraio MA, Mooney RA. Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis. J Appl Physiol 2007;102:814-816
    • (2007) J Appl Physiol , vol.102 , pp. 814-816
    • Pedersen, B.K.1    Febbraio, M.A.2    Mooney, R.A.3
  • 22
    • 0342506484 scopus 로고    scopus 로고
    • Regulation of energy substrate metabolism in the diabetic heart
    • DOI 10.1016/S0008-6363(97)00047-3, PII S9998636397000473
    • Stanley WC, Lopaschuk GD, McCormack JG. Regulation of energy substrate metabolism in the diabetic heart. Cardiovasc Res 1997;34:25-33 (Pubitemid 27261909)
    • (1997) Cardiovascular Research , vol.34 , Issue.1 , pp. 25-33
    • Stanley, W.C.1    Lopaschuk, G.D.2    McCormack, J.G.3
  • 23
    • 22544469153 scopus 로고    scopus 로고
    • AMP-activated protein kinase: A key stress signaling pathway in the heart
    • Young LH, Li J, Baron SJ, Russell RR. AMP-activated protein kinase: a key stress signaling pathway in the heart. Trends Cardiovasc Med 2005;15:110-118
    • (2005) Trends Cardiovasc Med , vol.15 , pp. 110-118
    • Young, L.H.1    Li, J.2    Baron, S.J.3    Russell, R.R.4
  • 25
    • 33751436631 scopus 로고    scopus 로고
    • Fat uses a TOLL-road to connect inflammation and diabetes
    • Kim JK. Fat uses a TOLL-road to connect inflammation and diabetes. Cell Metab 2006;4:417-418
    • (2006) Cell Metab , vol.4 , pp. 417-418
    • Kim, J.K.1
  • 26
    • 0242268894 scopus 로고    scopus 로고
    • Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice
    • Klover PJ, Zimmers TA, Koniaris LG, Mooney RA. Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice. Diabetes 2003;52:2784-2789
    • (2003) Diabetes , vol.52 , pp. 2784-2789
    • Klover, P.J.1    Zimmers, T.A.2    Koniaris, L.G.3    Mooney, R.A.4
  • 27
    • 8844255630 scopus 로고    scopus 로고
    • Free fatty acids in obesity and type 2 diabetes: Defining their role in the development of insulin resistance and beta-cell dysfunction
    • Boden G, Shulman GI. Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction. Eur J Clin Invest 2002;32:14-23
    • (2002) Eur J Clin Invest , vol.32 , pp. 14-23
    • Boden, G.1    Shulman, G.I.2
  • 28
    • 18844432308 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors
    • Kadowaki T, Yamauchi T. Adiponectin and adiponectin receptors. Endocr Rev 2005;26:439-451
    • (2005) Endocr Rev , vol.26 , pp. 439-451
    • Kadowaki, T.1    Yamauchi, T.2
  • 30
    • 4344614649 scopus 로고    scopus 로고
    • Regulation of insulin action by ceramide: Dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B
    • DOI 10.1074/jbc.M406499200
    • Stratford S, Hoehn KL, Liu F, Summers SA. Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B. J Biol Chem 2004;279:36608-36615 (Pubitemid 39129005)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.35 , pp. 36608-36615
    • Stratford, S.1    Hoehn, K.L.2    Liu, F.3    Summers, S.A.4
  • 31
    • 0030003249 scopus 로고    scopus 로고
    • Cloning and functional expression of mCCR2, a murine receptor for the C-C chemokines GE and FIC
    • DOI 10.1074/jbc.271.20.11603
    • Kurihara T, Bravo R. Cloning and functional expression of mCCR2, a murine receptor for the C-C chemokines JE and FIC. J Biol Chem 1996;271:11603-11607 (Pubitemid 26161808)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.20 , pp. 11603-11606
    • Kurihara, T.1    Bravo, R.2
  • 33
    • 0034625547 scopus 로고    scopus 로고
    • Plasma interleukin-6, tumour necrosis factor α and blood cytokine production in type 2 diabetes
    • DOI 10.1016/S0024-3205(00)00622-6, PII S0024320500006226
    • Pickup JC, Chusney GD, Thomas SM, Burt D. Plasma interleukin-6, tumor necrosis factor α and blood cytokine production in type 2 diabetes. Life Sci 2000;67:291-300 (Pubitemid 30413937)
    • (2000) Life Sciences , vol.67 , Issue.3 , pp. 291-300
    • Pickup, J.C.1    Chusney, G.D.2    Thomas, S.M.3    Burt, D.4
  • 36
    • 38749137749 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart
    • Miller EJ, Li J, Leng L, McDonald C, Atsumi T, Bucala R, Young LH. Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart. Nature 2008;451:578-583
    • (2008) Nature , vol.451 , pp. 578-583
    • Miller, E.J.1    Li, J.2    Leng, L.3    McDonald, C.4    Atsumi, T.5    Bucala, R.6    Young, L.H.7
  • 38
    • 3042739678 scopus 로고    scopus 로고
    • Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: Absence of development of age-related obesity
    • Di Gregorio GB, Hensley L, Lu T, Ranganathan G, Kern PA. Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity. Am J Physiol 2004;287:E182-E187
    • (2004) Am J Physiol , vol.287
    • Di Gregorio, G.B.1    Hensley, L.2    Lu, T.3    Ranganathan, G.4    Kern, P.A.5
  • 41
    • 33645808949 scopus 로고    scopus 로고
    • Exercise increases SOCS-3 expression in rat skeletal muscle: Potential relationship to IL-6 expression
    • Spangenburg EE, Brown DA, Johnson MS, Moore RL. Exercise increases SOCS-3 expression in rat skeletal muscle: potential relationship to IL-6 expression. J Physiol 2006;572:839-848
    • (2006) J Physiol , vol.572 , pp. 839-848
    • Spangenburg, E.E.1    Brown, D.A.2    Johnson, M.S.3    Moore, R.L.4
  • 42
    • 0036720342 scopus 로고    scopus 로고
    • Muscle derived interleukin-6: Mechanisms for activation and possible biological roles
    • Febbraio MA, Pedersen BK. Muscle derived interleukin-6: mechanisms for activation and possible biological roles. FASEB J 2002;16:1335-1347
    • (2002) FASEB J , vol.16 , pp. 1335-1347
    • Febbraio, M.A.1    Pedersen, B.K.2
  • 43
    • 0034658541 scopus 로고    scopus 로고
    • Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors
    • Hirano T, Ishihara K, Hibi M. Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors. Oncogene 2000;19:2548-2556 (Pubitemid 30339210)
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2548-2556
    • Hirano, T.1    Ishihara, K.2    Hibi, M.3
  • 45
    • 0036830636 scopus 로고    scopus 로고
    • SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2
    • DOI 10.1074/jbc.C200444200
    • Rui L, Yuan M, Frantz D, Shoelson S, White MF. SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2. J Biol Chem 2002;277:42394-42398 (Pubitemid 35257562)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.44 , pp. 42394-42398
    • Rui, L.1    Yuan, M.2    Frantz, D.3    Shoelson, S.4    White, M.F.5
  • 46
    • 0037853260 scopus 로고    scopus 로고
    • Suppressor of cytokine-signaling-3 (SCOS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes
    • Senn JJ, Klover PJ, Nowak IA, Zimmers TA, Koniaris LG, Furlanetto RW, Mooney RA. Suppressor of cytokine-signaling-3 (SCOS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes. J Biol Chem 2003;278:13740-13746
    • (2003) J Biol Chem , vol.278 , pp. 13740-13746
    • Senn, J.J.1    Klover, P.J.2    Nowak, I.A.3    Zimmers, T.A.4    Koniaris, L.G.5    Furlanetto, R.W.6    Mooney, R.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.