-
1
-
-
0032555020
-
Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease
-
AALTONEN LA, SALOVAARA R, KRISTO P, CANZIAN F, HEMMINKI A, PELTOMAKI P, CHADWICK RB, KAARIAINEN H, ESKELINEN M, JARVINEN H, MECKLIN JP, DE LA CHAPELLE A: Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease. N Engl J Med 338: 1481-1487, 1998.
-
(1998)
N Engl J Med
, vol.338
, pp. 1481-1487
-
-
Aaltonen La1
Salovaara, R.2
Kristo, P.3
Canzian, F.4
Hemminki, A.5
Peltomaki, P.6
Chadwick, R.B.7
Kaariainen, H.8
Eskelinen, M.9
Jarvinen, H.10
Mecklin, J.P.11
De la Chapelle, A.12
-
2
-
-
0029861118
-
Fanconi's anemia and malignancies
-
ALTER BP: Fanconi's anemia and malignancies. Am J Hematol 53: 99-110, 1996.
-
(1996)
Am J Hematol
, vol.53
, pp. 99-110
-
-
Alter, B.P.1
-
3
-
-
0036223483
-
Radiosensitivity in Fanconi's anemia patients
-
ALTER BP: Radiosensitivity in Fanconi's anemia patients. Radiother Oncol 62: 345-347, 2002.
-
(2002)
Radiother Oncol
, vol.62
, pp. 345-347
-
-
Alter, B.P.1
-
4
-
-
4043133287
-
ATR couples FANCD2 monoubiquitination to the DNAdamage response
-
ANDREASSEN PR, D'ANDREA AD, TANIGUCHI T: ATR couples FANCD2 monoubiquitination to the DNAdamage response. Genes Dev 18: 1958-1963, 2004.
-
(2004)
Genes Dev
, vol.18
, pp. 1958-1963
-
-
Andreassen, P.R.1
D'Andrea, A.D.2
Taniguchi, T.3
-
5
-
-
77955039099
-
Oral poly(ADP ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial
-
AUDEH MW, CARMICHAEL J, PENSON RT, FRIEDLANDER M, POWELL B, BELL-MCGUINN KM, SCOTT C, WEITZEL JN, OAKNIN A, LOMAN N, LU K, SCHMUTZLER RK, MATULONIS U, WICKENS M, TUTT A: Oral poly(ADP ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. Lancet 376: 245-251, 2010.
-
(2010)
Lancet
, vol.376
, pp. 245-251
-
-
Audeh, M.W.1
Carmichael, J.2
Penson, R.T.3
Friedlander, M.4
Powell, B.5
Bell-Mcguinn, K.M.6
Scott, C.7
Weitzel, J.N.8
Oaknin, A.9
Loman, N.10
Lu, K.11
Schmutzler, R.K.12
Matulonis, U.13
Wickens, M.14
Tutt, A.15
-
6
-
-
0027861014
-
Fanconi anemia diagnosis and the diepoxybutane (DEB) test
-
AUERBACH AD: Fanconi anemia diagnosis and the diepoxybutane (DEB) test. Exp Hematol 21: 731-733, 1993.
-
(1993)
Exp Hematol
, vol.21
, pp. 731-733
-
-
Auerbach, A.D.1
-
7
-
-
14844356005
-
DNA interstrand cross-link repair in the Saccharomyces cerevisiae cell cycle: overlapping roles for PSO2 (SNM1) with MutS factors and EXO1 during S phase
-
BARBER LJ, WARD TA, HARTLEY JA, MCHUGH PJ: DNA interstrand cross-link repair in the Saccharomyces cerevisiae cell cycle: overlapping roles for PSO2 (SNM1) with MutS factors and EXO1 during S phase. Mol Cell Biol 25: 2297-2309, 2005.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2297-2309
-
-
Barber, L.J.1
Ward, T.A.2
Hartley, J.A.3
Mchugh, P.J.4
-
8
-
-
10944251591
-
Repair and genetic consequences of endogenous DNA base damage in mammalian cells
-
BARNES DE, LINDAHL T: Repair and genetic consequences of endogenous DNA base damage in mammalian cells. Annu Rev Genet 38: 445-476, 2004.
-
(2004)
Annu Rev Genet
, vol.38
, pp. 445-476
-
-
Barnes, D.E.1
Lindahl, T.2
-
9
-
-
0037080115
-
Effect of BRCA mutations on the length of survival in epithelial ovarian tumors
-
NATIONAL ISRAELI STUDY OF OVARIAN CANCER
-
BEN DAVID Y, CHETRIT A, HIRSH-YECHEZKEL G, FRIEDMAN E, BECK BD, BELLER U, BEN-BARUCH G, FISHMAN A, LEVAVI H, LUBIN F, MENCZER J, PIURA B, STRUEWING JP, MODAN B; NATIONAL ISRAELI STUDY OF OVARIAN CANCER: Effect of BRCA mutations on the length of survival in epithelial ovarian tumors. J Clin Oncol 20: 463-466, 2002.
-
(2002)
J Clin Oncol
, vol.20
, pp. 463-466
-
-
Ben David, Y.1
Chetrit, A.2
Hirsh-Yechezkel, G.3
Friedman, E.4
Beck, B.D.5
Beller, U.6
Ben-Baruch, G.7
Fishman, A.8
Levavi, H.9
Lubin, F.10
Menczer, J.11
Piura, B.12
Struewing, J.P.13
Modan, B.14
-
10
-
-
41149094512
-
Regulation of DNA repair throughout the cell cycle
-
BRANZEI D, FOIANI M: Regulation of DNA repair throughout the cell cycle. Nat Rev Mol Cell Biol 9: 297-308, 2008.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 297-308
-
-
Branzei, D.1
Foiani, M.2
-
11
-
-
17244375049
-
Specific killing of BRCA2-deficient tumourswith inhibitors of poly(ADP-ribose) polymerase
-
BRYANT HE, SCHULTZ N, THOMAS HD, PARKER KM, FLOWER D, LOPEZ E, KYLE S, MEUTH M, CURTIN NJ, HELLEDAY T: Specific killing of BRCA2-deficient tumourswith inhibitors of poly(ADP-ribose) polymerase. Nature 434: 913-916, 2005.
-
(2005)
Nature
, vol.434
, pp. 913-916
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
Parker, K.M.4
Flower, D.5
Lopez, E.6
Kyle, S.7
Meuth, M.8
Curtin, N.J.9
Helleday, T.10
-
12
-
-
1442281478
-
The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations
-
CANTOR S, DRAPKIN R, ZHANG F, LIN Y, HAN J, PAMIDI S, LIVINGSTONE DM: The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations. Proc Natl Acad Sci U S A 101: 2357-2362, 2004.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2357-2362
-
-
Cantor, S.1
Drapkin, R.2
Zhang, F.3
Lin, Y.4
Han, J.5
Pamidi, S.6
Livingstone, D.M.7
-
13
-
-
0036336280
-
Analysis of the Fanconi anaemia complementation group A gene in acute myeoloid leukaemia
-
CONDIE A, POWLES RL, HUDSON CD, SHEPHERD V, BEVAN S, YUILLE MR, HOULSTON RS: Analysis of the Fanconi anaemia complementation group A gene in acute myeoloid leukaemia. Leuk Lymphoma 43: 1849-1853, 2002.
-
(2002)
Leuk Lymphoma
, vol.43
, pp. 1849-1853
-
-
Condie, A.1
Powles, R.L.2
Hudson, C.D.3
Shepherd, V.4
Bevan, S.5
Yuille, M.R.6
Houlston, R.S.7
-
14
-
-
12544255089
-
Germ line Fanconi anemia complementation group C mutations and pancreatic cancer
-
COUCH FJ, JOHNSON MR, RABE K, BOARDMAN L, MCWILLIAMS R, DE ANDRADE M, PETERSEN G: Germ line Fanconi anemia complementation group C mutations and pancreatic cancer. Cancer Res 65: 383-386, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 383-386
-
-
Couch, F.J.1
Johnson, M.R.2
Rabe, K.3
Boardman, L.4
Mcwilliams, R.5
De Andrade, M.6
Petersen, G.7
-
15
-
-
0037268338
-
The Fanconi anaemia/BRCA pathway
-
D'ANDREA AD, GROMPE M: The Fanconi anaemia/BRCA pathway. Nat Rev Cancer 3: 23-34, 2003.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 23-34
-
-
D'Andrea, A.D.1
Grompe, M.2
-
16
-
-
77952600845
-
Susceptibility pathways in Fanconi's anemia and breast cancer
-
D'ANDREA AD: Susceptibility pathways in Fanconi's anemia and breast cancer. N Engl J Med 362: 1909-1919, 2010.
-
(2010)
N Engl J Med
, vol.362
, pp. 1909-1919
-
-
D'Andrea, A.D.1
-
17
-
-
0033781210
-
Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstand cross-links in mammalian cells
-
DE SILVA IU, MCHUGH PJ, CLINGEN PH, HARTLEY JA: Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstand cross-links in mammalian cells. Mol Cell Biol 20: 7980-7990, 2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 7980-7990
-
-
De Silva, I.U.1
Mchugh, P.J.2
Clingen, P.H.3
Hartley, J.A.4
-
18
-
-
77955847245
-
Multiple roles of ATM in monitoring and maintaining DNA intergrity
-
DERHEIMER FA, KASTAN MB: Multiple roles of ATM in monitoring and maintaining DNA intergrity. FEBS Lett 584: 3675-3681, 2010.
-
(2010)
FEBS Lett
, vol.584
, pp. 3675-3681
-
-
Derheimer, F.A.1
Kastan, M.B.2
-
19
-
-
13644254920
-
CpG methylation of the FHIT, FANCF, cyclin-D2, BRCA2 and RUNX3 genes in Granulosa cell tumors (GCTs) of ovarian origin
-
DHILLON VS, SHAHID M, HUSAIN SA: CpG methylation of the FHIT, FANCF, cyclin-D2, BRCA2 and RUNX3 genes in Granulosa cell tumors (GCTs) of ovarian origin. Mol Cancer 3: 33, 2004.
-
(2004)
Mol Cancer
, vol.3
, pp. 33
-
-
Dhillon, V.S.1
Shahid, M.2
Husain, S.A.3
-
20
-
-
0036491931
-
The BRCA1 suppressor hypothesis: an explanation for the tissue-specific tumor development in BRCA1 patients
-
ELLEDGE SJ, AMON A: The BRCA1 suppressor hypothesis: an explanation for the tissue-specific tumor development in BRCA1 patients. Cancer Cell 1: 129-132, 2002.
-
(2002)
Cancer Cell
, vol.1
, pp. 129-132
-
-
Elledge, S.J.1
Amon, A.2
-
21
-
-
79960954284
-
Clinical characteristics and outcomes of BRCA-associated ovarian cancer (OC): Genotype and survival
-
ENGELSTAEDTER V, CRISTEA MC, GARBER JE, NEUHAUSEN SL, FRANKEL PH, SAND S, STEELE L, MATULONIS U, LIU J, WEITZEL J: Clinical characteristics and outcomes of BRCA-associated ovarian cancer (OC): Genotype and survival. J Clin Oncol 28: 15s, 2010.
-
(2010)
J Clin Oncol
, vol.28
-
-
Engelstaedter, V.1
Cristea, M.C.2
Garber, J.E.3
Neuhausen, S.L.4
Frankel, P.H.5
Sand, S.6
Steele, L.7
Matulonis, U.8
Liu, J.9
Weitzel, J.10
-
22
-
-
52449111109
-
Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin
-
EVERS B, DROST R, SCHUT E, DE BRUIN M, VAN DER BURG E, DERKSEN PW, HOLSTEGE H, LIU X, VAN DRUNEN E, BEVERLOO HB, SMITH GC, MARTIN NM, LAU A, O'CONNOR MJ, JONKERS J: Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin. Clin Cancer Res 14: 3916-3925, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3916-3925
-
-
Evers, B.1
Drost, R.2
Schut, E.3
De Bruin, M.4
Van Der Burg, E.5
Derksen, P.W.6
Holstege, H.7
Liu, X.8
Van Drunen, E.9
Beverloo, H.B.10
Smith, G.C.11
Martin, N.M.12
Lau, A.13
O'connor, M.J.14
Jonkers, J.15
-
23
-
-
77955278619
-
Targeting homologous recombination repair defects in cancer
-
EVERS B, HELLEDAY T, JONKER J: Targeting homologous recombination repair defects in cancer. Trends Pharmacol Sci 31: 372-380, 2010.
-
(2010)
Trends Pharmacol Sci
, vol.31
, pp. 372-380
-
-
Evers, B.1
Helleday, T.2
Jonker, J.3
-
24
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
FARMER H, MCCABE N, LORD CJ, TUTT ANJ, JOHNSON DA, RICHARDSON TB, SANTAROSA M, DILLON KJ, HICKSON I, KNIGHTS C, MARTIN NMB, JACKSON SP, SMITH GCM, ASHWORT A: Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 434: 917-921, 2005.
-
(2005)
Nature
, vol.434
, pp. 917-921
-
-
Farmer, H.1
Mccabe, N.2
Lord, C.J.3
Tutt, A.N.J.4
Johnson, D.A.5
Richardson, T.B.6
Santarosa, M.7
Dillon, K.J.8
Hickson, I.9
Knights, C.10
Martin, N.M.B.11
Jackson, S.P.12
Smith, G.C.M.13
Ashwort, A.14
-
26
-
-
25144445294
-
BRCA1 and BRCA2 pathways and the risk o cancers other than breast or ovarian
-
FRIEDENSON B: BRCA1 and BRCA2 pathways and the risk o cancers other than breast or ovarian. MedGenMed 7: 60, 2005.
-
(2005)
MedGenMed
, vol.7
, pp. 60
-
-
Friedenson, B.1
-
27
-
-
33746488809
-
DNA repair: from molecular mechanisms to human disease
-
FRIEDBERG EC, AGUILERA A, GELLERT M, HANAWALT PC, HAYS JB, LEHMANN AR, LINDAHL T, LOWNDES N, SARASIN A, WOOD RD: DNA repair: from molecular mechanisms to human disease. DNA Repair (Amst) 5: 986-996, 2006.
-
(2006)
DNA Repair (Amst)
, vol.5
, pp. 986-996
-
-
Friedberg, E.C.1
Aguilera, A.2
Gellert, M.3
Hanawalt, P.C.4
Hays, J.B.5
Lehmann, A.R.6
Lindahl, T.7
Lowndes, N.8
Sarasin, A.9
Wood, R.D.10
-
28
-
-
33744539631
-
Targeted disruption of FANCC and FANCG in human cancer provides a preclinical model for specific therapeutic options
-
GALLMEIER E, CALHOUN ES, RAGO C, BRODY JR, CUNNINGHAM SC, HUCL T, GOROSPE M, KOHLI M, LENGAUER C, KERN SE: Targeted disruption of FANCC and FANCG in human cancer provides a preclinical model for specific therapeutic options. Gastroenterology 130: 2145-2154, 2006.
-
(2006)
Gastroenterology
, vol.130
, pp. 2145-2154
-
-
Gallmeier, E.1
Calhoun, E.S.2
Rago, C.3
Brody, J.R.4
Cunningham, S.C.5
Hucl, T.6
Gorospe, M.7
Kohli, M.8
Lengauer, C.9
Kern, S.E.10
-
29
-
-
33947213975
-
High-throughput screening identifies novel agents eliciting hypersensitivity in Fanconi pathway-deficient cancer cells
-
GALLMEIER E, HUCL T, BRODY JR, DEZENTJE DA, TAHIR K, KASPARKOVA J, BRABEC V, BACHMAN KE, KERN SE: High-throughput screening identifies novel agents eliciting hypersensitivity in Fanconi pathway-deficient cancer cells. Cancer Res 67: 2169-2177, 2007a.
-
(2007)
Cancer Res
, vol.67
, pp. 2169-2177
-
-
Gallmeier, E.1
Hucl, T.2
Brody, J.R.3
Dezentje, D.A.4
Tahir, K.5
Kasparkova, J.6
Brabec, V.7
Bachman, K.E.8
Kern, S.E.9
-
30
-
-
25144432400
-
Absence of specific cell killing of the BRCA2-deficient human cancer cell line CAPAN1 by poly(ADP-ribose) polymerase inhibition
-
GALLMEIER E, KERN SE: Absence of specific cell killing of the BRCA2-deficient human cancer cell line CAPAN1 by poly(ADP-ribose) polymerase inhibition. Cancer Biol Ther 4: 703-706, 2005.
-
(2005)
Cancer Biol Ther
, vol.4
, pp. 703-706
-
-
Gallmeier, E.1
Kern, S.E.2
-
31
-
-
34548247158
-
Gene-specific selection against experimental fanconi anemia gene inactivation in human cancer
-
GALLMEIER E, HUCL T, CALHOUN ES, CUNNINGHAM SC, BUNZ F, BRODY JR, KERN SE: Gene-specific selection against experimental fanconi anemia gene inactivation in human cancer. Cancer Biol Ther 6: 654-660, 2007b.
-
(2007)
Cancer Biol Ther
, vol.6
-
-
Gallmeier, E.1
Hucl, T.2
Calhoun, E.S.3
Cunningham, S.C.4
Bunz, F.5
Brody, J.R.6
Kern, S.E.7
-
32
-
-
33846333535
-
Targeting fanconi anemia/BRCA2 pathway defects in cancer: the significance of preclinical pharmacogenomic models
-
GALLMEIER E, KERN SE: Targeting fanconi anemia/BRCA2 pathway defects in cancer: the significance of preclinical pharmacogenomic models. Clin Cancer Res 13: 4-9, 2007.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4-9
-
-
Gallmeier, E.1
Kern, S.E.2
-
33
-
-
12644253827
-
Germline BRCA2ge ne mutations in patients with apparently sporadic pancreatic carcinomas
-
GOGGINS M, SCHUTTE M, LU J, MOSKALUK CA, WEINSTEIN CL, PETERSEN GM, YEO CJ, JACKSON CE, LYNCH HT, HRUBAN RH, KERN SE: Germline BRCA2ge ne mutations in patients with apparently sporadic pancreatic carcinomas. Cancer Res 56: 5360-5364, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 5360-5364
-
-
Goggins, M.1
Schutte, M.2
Lu, J.3
Moskaluk, C.A.4
Weinstein, C.L.5
Petersen, G.M.6
Yeo, C.J.7
Jackson, C.E.8
Lynch, H.T.9
Hruban, R.H.10
Kern, S.E.11
-
34
-
-
0028125830
-
Evaluation of granulocyte-macrophage colonystimulating factor for treatment of pancytopenia in children with fanconi anemia
-
GUINAN EC, LOPEZ KD, HUHN RD, FELSER JM, NATHAN DG: Evaluation of granulocyte-macrophage colonystimulating factor for treatment of pancytopenia in children with fanconi anemia. J Pediatr 14: 144-150, 1994.
-
(1994)
J Pediatr
, vol.14
, pp. 144-150
-
-
Guinan, E.C.1
Lopez, K.D.2
Huhn, R.D.3
Felser, J.M.4
Nathan, D.G.5
-
35
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
HAHN SA, SCHUTTE M, HOQUE AT, MOSKALUK CA, DA COSTA LT, ROZENBLUM E, WEINSTEIN CL, FISCHER A, YEO CJ, HRUBAN RH, KERN SE: DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271: 350-353, 1996.
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.3
Moskaluk, C.A.4
Da Costa, L.T.5
Rozenblum, E.6
Weinstein, C.L.7
Fischer, A.8
Yeo, C.J.9
Hruban, R.H.10
Kern, S.E.11
-
36
-
-
0037420026
-
BRCA2 germline mutations in familial pancreatic carcinoma
-
HAHN SA, GREENHALF B, ELLIS I, SINA-FREY M, RIEDER H, KORTE B, GERDES B, KRESS R, ZIEGLER A, RAEBURN JA, CAMPRA D, GRUTZMANN R, REHDER H, ROTHMUND M, SCHMIEGEL W, NEOPTOLEMOS JP, BARTSCH DK: BRCA2 germline mutations in familial pancreatic carcinoma. J Natl Cancer Inst 95: 214-221, 2003.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 214-221
-
-
Hahn, S.A.1
Greenhalf, B.2
Ellis, I.3
Sina-Frey, M.4
Rieder, H.5
Korte, B.6
Gerdes, B.7
Kress, R.8
Ziegler, A.9
Raeburn, J.A.10
Campra, D.11
Grutzmann, R.12
Rehder, H.13
Rothmund, M.14
Schmiegel, W.15
Neoptolemos, J.P.16
Bartsch, D.K.17
-
37
-
-
0034500024
-
DNA mismatch repair and genetic instability
-
HARFE BD, JINKS-ROBERTSON S: DNA mismatch repair and genetic instability. Annu Rev Genet 34: 359-399, 2000.
-
(2000)
Annu Rev Genet
, vol.34
, pp. 359-399
-
-
Harfe, B.D.1
Jinks-Robertson, S.2
-
38
-
-
0030667434
-
Integrating genetic approaches into the discovery of anticancer drugs
-
HARTWELL L, SZANKASI P, ROBERTS C, MURRAY A, FRIEND S: Integrating genetic approaches into the discovery of anticancer drugs. Science 278: 1064-1068, 1997.
-
(1997)
Science
, vol.278
, pp. 1064-1068
-
-
Hartwell, L.1
Szankasi, P.2
Roberts, C.3
Murray, A.4
Friend, S.5
-
39
-
-
77952319560
-
The role of radiation therapy in pancreas cancer
-
HAZARD L: The role of radiation therapy in pancreas cancer. Gastrointest Cancer Res 3: 20-28, 2009.
-
(2009)
Gastrointest Cancer Res
, vol.3
, pp. 20-28
-
-
Hazard, L.1
-
40
-
-
34249945536
-
DNA double-strand break repair: from mechanistic understanding to cancer treatment
-
HELLEDAY T, LO J, VAN GENT DC, ENGELWARD BP: DNA double-strand break repair: from mechanistic understanding to cancer treatment. DNA Repair (Amst) 6: 923-935, 2007.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 923-935
-
-
Helleday, T.1
Lo, J.2
Van Gent, D.C.3
Engelward, B.P.4
-
41
-
-
0035902108
-
Genome maintenance mechanisms for preventing cancer
-
HOEIJMAKERS JHJ: Genome maintenance mechanisms for preventing cancer. Nature 411: 366-374, 2001.
-
(2001)
Nature
, vol.411
, pp. 366-374
-
-
Hoeijmakers, J.H.J.1
-
42
-
-
77955259651
-
Successful treatment of esophageal squamous cell carcinoma in a patient with Fanconi anemia
-
HOSOYA Y, LEFOR Y, HIRASHIMA Y, NOKUBI M, YAMAGUTI T, JINBU Y, MUROI K, NAKAZAWA M, YASUDA Y: Successful treatment of esophageal squamous cell carcinoma in a patient with Fanconi anemia. Jpn J Clin Oncol 40: 805-810, 2010.
-
(2010)
Jpn J Clin Oncol
, vol.40
, pp. 805-810
-
-
Hosoya, Y.1
Lefor, Y.2
Hirashima, Y.3
Nokubi, M.4
Yamaguti, T.5
Jinbu, Y.6
Muroi, K.7
Nakazawa, M.8
Yasuda, Y.9
-
43
-
-
0033532342
-
Action of DNA repair endonuclease ERCC1/XPF in living cells
-
HOUTSMULLER AB, RADEMAKERS S, NIGG AL, HOOGSTRATEN D, HOEIJMAKERS JH, VERMEULEN W: Action of DNA repair endonuclease ERCC1/XPF in living cells. Science 284: 958-961, 1999.
-
(1999)
Science
, vol.284
, pp. 958-961
-
-
Houtsmuller, A.B.1
Rademakers, S.2
Nigg, A.L.3
Hoogstraten, D.4
Hoeijmakers, J.H.5
Vermeulen, W.6
-
44
-
-
18444362122
-
Biallelic inactivation of BRCA2 in Fanconi anemia
-
HOWLETT NG, TANIGUCHI T, OLSON S, COX B, WAISFISZ Q, DE DIE-SMULDERS C, PERSKY N, GROMPE M, JOENJE H, PALS G, IKEDA H, FOX EA, D'ANDREA AD: Biallelic inactivation of BRCA2 in Fanconi anemia. Science 297: 606-609, 2002.
-
(2002)
Science
, vol.297
, pp. 606-609
-
-
Howlett, N.G.1
Taniguchi, T.2
Olson, S.3
Cox, B.4
Waisfisz, Q.5
De Die-Smulders, C.6
Persky, N.7
Grompe, M.8
Joenje, H.9
Pals, G.10
Ikeda, H.11
Fox, E.A.12
D'andrea, A.D.13
-
45
-
-
48549084778
-
A syngeneic variance library for functional annotation of human variation: application to BRCA2
-
HUCL T, RAGO C, GALLMEIER E, BRODY JR, GOROSPE M, KERN SE: A syngeneic variance library for functional annotation of human variation: application to BRCA2. Cancer Res 68: 5023-5030, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 5023-5030
-
-
Hucl, T.1
Rago, C.2
Gallmeier, E.3
Brody, J.R.4
Gorospe, M.5
Kern, S.E.6
-
46
-
-
34547686652
-
Distinguishing rational from irrational applications of pharmacogenetic synergies from the bench to clinical trials
-
HUCL T, GALLMEIER E, KERN SE: Distinguishing rational from irrational applications of pharmacogenetic synergies from the bench to clinical trials. Cell Cycle 6: 1336-1341, 2007.
-
(2007)
Cell Cycle
, vol.6
, pp. 1336-1341
-
-
Hucl, T.1
Gallmeier, E.2
Kern, S.E.3
-
47
-
-
55549137026
-
FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway
-
ISHIAI M, KITAO H, SMOGORZEWSKA A, TOMIDA J, KINOMURA A, UCHIDA E, SABERI A, KINOSHITA E, KINOSHITA-KIKUTA E, KOIKE T, TASHIRO S, ELLEDGE SJ, TAKATA M: FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway. Nat Struct Mol Biol 15: 1138-1146, 2008.
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 1138-1146
-
-
Ishiai, M.1
Kitao, H.2
Smogorzewska, A.3
Tomida, J.4
Kinomura, A.5
Uchida, E.6
Saberi, A.7
Kinoshita, E.8
Kinoshita-Kikuta, E.9
Koike, T.10
Tashiro, S.11
Elledge, S.J.12
Takata, M.13
-
48
-
-
64849092309
-
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene
-
JONES S, HRUBAN RH, KAMIYAMA M, BORGES M, ZHANG X, PARSONS DW, LIN JC, PALMISANO E, BRUNE K, JAFFEE EM, IACOBUZIO-DONAHUE CA, MAITRA A, PARMIGIANI G, KERN SE, VELCULESCU VE, KINZLER KW, VOGELSTEIN B, ESHLEMAN JR, GOGGINS M, KLEIN AP: Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene. Science 324: 217, 2009.
-
(2009)
Science
, vol.324
, pp. 217
-
-
Jones, S.1
Hruban, R.H.2
Kamiyama, M.3
Borges, M.4
Zhang, X.5
Parsons, D.W.6
Lin, J.C.7
Palmisano, E.8
Brune, K.9
Jaffee, E.M.10
Iacobuzio-Donahue, C.A.11
Maitra, A.12
Parmigiani, G.13
Kern, S.E.14
Velculescu, V.E.15
Kinzler, K.W.16
Vogelstein, B.17
Eshleman, J.R.18
Goggins, M.19
Klein, A.P.20
more..
-
49
-
-
25444497278
-
The concept of synthetic lethality in the context of anticancer therapy
-
KAELIN WG: The concept of synthetic lethality in the context of anticancer therapy. Nature Rev Cancer 5: 689-698, 2005.
-
(2005)
Nature Rev Cancer
, vol.5
, pp. 689-698
-
-
Kaelin, W.G.1
-
50
-
-
2442658200
-
Lack of sensitivity of primary Fanconi's anemia fibroblast to UV and ionizing radiation
-
KALB R, DUERR M, WAGNER M, HERTERICH S, GROSS M, DIGWEED M, JOENJE H, HOEHN H, SCHINDLER D: Lack of sensitivity of primary Fanconi's anemia fibroblast to UV and ionizing radiation. Radiat Res 161: 318-325, 2004.
-
(2004)
Radiat Res
, vol.161
, pp. 318-325
-
-
Kalb, R.1
Duerr, M.2
Wagner, M.3
Herterich, S.4
Gross, M.5
Digweed, M.6
Joenje, H.7
Hoehn, H.8
Schindler, D.9
-
51
-
-
33747376928
-
DNA repair pathway in clinical practice: lessons from pediatric cancer susceptibility syndromes
-
KENNEDY RD, D'ANDREA AD: DNA repair pathway in clinical practice: lessons from pediatric cancer susceptibility syndromes. J Clin Oncol 24: 3799-3808, 2006.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3799-3808
-
-
Kennedy, R.D.1
D'andrea, A.D.2
-
52
-
-
34248184445
-
Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated
-
KENNEDY RD, CHEN CC, STUCKERT P, ARCHILA EM, DE LA VEGA MA, MOREAU LA, SHIMAURA A, D'ANDREA AD: Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated. J Clin Invest 117: 1440-1449, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 1440-1449
-
-
Kennedy, R.D.1
Chen, C.C.2
Stuckert, P.3
Archila, E.M.4
De La Vega, M.A.5
Moreau, L.A.6
Shimaura, A.7
D'andrea, A.D.8
-
53
-
-
0142178215
-
Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2
-
KING MC, MARKS JH, MANDELL JB: Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Science 302: 643-646, 2003.
-
(2003)
Science
, vol.302
, pp. 643-646
-
-
King, M.C.1
Marks, J.H.2
Mandell, J.B.3
-
54
-
-
72949123930
-
The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair
-
KNIPSCHEER P, RASCHLE M, SMOGORZEWSKA A, ENOIU M, HO TV, SCHARER OD, ELLEDGE SJ, WALTER JC: The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair. Science 326: 1698-1701, 2009.
-
(2009)
Science
, vol.326
, pp. 1698-1701
-
-
Knipscheer, P.1
Raschle, M.2
Smogorzewska, A.3
Enoiu, M.4
Ho, T.V.5
Scharer, O.D.6
Elledge, S.J.7
Walter, J.C.8
-
55
-
-
77955894453
-
Gene expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer
-
KONSTANTINOPOULOS PA, SPENTZOS D, KARLAN BY, TANIGUCHI T, FOUNTZILAS E, FRANCOEUR N, LEVINE DA, CANNISTRA SA: Gene expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer. J Clin Oncol 28: 3555-3561, 2010.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3555-3561
-
-
Konstantinopoulos, P.A.1
Spentzos, D.2
Karlan, B.Y.3
Taniguchi, T.4
Fountzilas, E.5
Francoeur, N.6
Levine, D.A.7
Cannistra, S.A.8
-
56
-
-
33746775293
-
Translesion synthesis in mammalian cells
-
LEHMANN AR: Translesion synthesis in mammalian cells. Exp Cell Res 12: 2673-2676, 2006.
-
(2006)
Exp Cell Res
, vol.12
, pp. 2673-2676
-
-
Lehmann, A.R.1
-
57
-
-
25144457604
-
The DNA helicase BRIP1 is defective in Fanconi anemia complementation group
-
LEVITUS M, WAISISZ Q, GODTHELP BC, DE VRIES Y, HUSSAIN S, WIEGANT WW, ELGHALBZOURIMAGHRANI E, STELTENPOOL J, ROOIMANS MA, PALS G, ARWERT F, MATHEW CG, ZDZIENICKA MZ, HIOM K, DE WINTER JP, JOENJE H: The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J. Nat Genet 37: 934-935, 2005.
-
(2005)
J Nat Genet
, vol.37
, pp. 934-935
-
-
Levitus, M.1
Waisisz, Q.2
Godthelp, B.C.3
De Vries, Y.4
Hussain, S.5
Wiegant, W.W.6
Elghalbzourimaghrani, E.7
Steltenpool, J.8
Rooimans, M.A.9
Pals, G.10
Arwert, F.11
Mathew, C.G.12
Zdzienicka, M.Z.13
Hiom, K.14
De Winter, J.P.15
Joenje, H.16
-
58
-
-
0033520969
-
Quality control by DNA repair
-
LINDAHL T, WOOD RD: Quality control by DNA repair. Science 286: 1897-1905, 1999.
-
(1999)
Science
, vol.286
, pp. 1897-1905
-
-
Lindahl, T.1
Wood, R.D.2
-
59
-
-
77955290719
-
FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair
-
LIU T, GHOSAL G, YUAN J, CHEN J, HUANG J: FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair. Science 329: 693-696, 2010.
-
(2010)
Science
, vol.329
, pp. 693-696
-
-
Liu, T.1
Ghosal, G.2
Yuan, J.3
Chen, J.4
Huang, J.5
-
60
-
-
0003422388
-
DNA replication, repair, and recombination
-
LODISH H, BERK A, ZIPURSKY SL, MATSUDAIRA P, BALTIMORE D, DARNELL JE (eds), W.H. Freeman and Company, New York
-
LODISH H: DNA replication, repair, and recombination. In: Molecular Cell Biology. LODISH H, BERK A, ZIPURSKY SL, MATSUDAIRA P, BALTIMORE D, DARNELL JE (eds), W.H. Freeman and Company, New York, 2000, pp 453-494.
-
(2000)
Molecular Cell Biology
, pp. 453-494
-
-
Lodish, H.1
-
61
-
-
1342301467
-
Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: implications for treatment and survival
-
MARSIT CJ, LIU M, NELSON JJ, POSNER M, SUZUKI M, KELSEY KT. Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: implications for treatment and survival. Oncogene 23: 1000-1004, 2004.
-
(2004)
Oncogene
, vol.23
, pp. 1000-1004
-
-
Marsit, C.J.1
Liu, M.2
Nelson, J.J.3
Posner, M.4
Suzuki, M.5
Kelsey, K.T.6
-
62
-
-
62549124623
-
Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing
-
MCMANUS KJ, BARRETT IJ, NOUHI Y, HIETER P: Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing. Proc Natl Acad Sci U S A 106: 3276-3281, 2009.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 3276-3281
-
-
Mcmanus, K.J.1
Barrett, I.J.2
Nouhi, Y.3
Hieter, P.4
-
63
-
-
43849098620
-
The Fanconi anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly
-
MIRCHANDANI KD, MCCAFFREY RM, D'ANDREA AD: The Fanconi anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly. DNA Repair (Amst) 7: 902-911, 2008.
-
(2008)
DNA Repair (Amst)
, vol.7
, pp. 902-911
-
-
Mirchandani, K.D.1
Mccaffrey, R.M.2
D'Andrea, A.D.3
-
64
-
-
72149119542
-
How the Fanconi anemia pathway guards the genome
-
MOLDOVAN GL, D'ANDREA AD: How the Fanconi anemia pathway guards the genome. Annu Rev Genet 43: 223-249, 2009.
-
(2009)
Annu Rev Genet
, vol.43
, pp. 223-249
-
-
Moldovan, G.L.1
D'Andrea, A.D.2
-
65
-
-
77950974130
-
Development of a functional assay for homologous recombination status in primary cultures of epithelial ovarian tumor and correlation with sensitivity to poly(ADP-ribose) polymerase inhibitors
-
MUKHOPADHYAY A, ALATTAR A, CERBINSKAITE A, WILKINSON SJ, DREW Y, KYLE S, LOS G, HOSTOMSKY Z, EDMONDSON RJ, CURTIN NJ: Development of a functional assay for homologous recombination status in primary cultures of epithelial ovarian tumor and correlation with sensitivity to poly(ADP-ribose) polymerase inhibitors. Clin Cancer Res 16: 2344-2351, 2010.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2344-2351
-
-
Mukhopadhyay, A.1
Alattar, A.2
Cerbinskaite, A.3
Wilkinson, S.J.4
Drew, Y.5
Kyle, S.6
Los, G.7
Hostomsky, Z.8
Edmondson, R.J.9
Curtin, N.J.10
-
66
-
-
0036644884
-
Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17 %
-
MURPHY KM, BRUNE KA, GRIFFIN N, SOLLENBERGER JE, PETERSEN GM, BANSAL R, HRUBAN RH, KERN SE: Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17 %. Cancer Res 62: 3789-3793, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 3789-3793
-
-
Murphy, K.M.1
Brune, K.A.2
Griffin, N.3
Sollenberger, J.E.4
Petersen, G.M.5
Bansal, R.6
Hruban, R.H.7
Kern, S.E.8
-
67
-
-
34248585737
-
Sporadic colorectal cancer and individual susceptibility: a review of the association studies investigating the role of DNA repair genetic polymorphisms
-
NACCARATI A, PARDINI B, HEMMINKI K, VODICKA P: Sporadic colorectal cancer and individual susceptibility: a review of the association studies investigating the role of DNA repair genetic polymorphisms. Mutat Res 635: 118-145, 2007.
-
(2007)
Mutat Res
, vol.635
, pp. 118-145
-
-
Naccarati, A.1
Pardini, B.2
Hemminki, K.3
Vodicka, P.4
-
68
-
-
2342633174
-
Promoter hypermethylation of FANCF: disruption of Fanconi anemia-BRCA pathway in cervical cancer
-
NARAYAN G, ARIAS-PULIDO H, NANDULA SV, BASSO K, SUGIRTHARAJ DD, VARGAS H, MANSUKHANI M, VILLELLA J, MEYER L, SCHNEIDER A, GISSMANN L, DURST M, POTHURI B, MURTY VV: Promoter hypermethylation of FANCF: disruption of Fanconi anemia-BRCA pathway in cervical cancer. Cancer Res 64: 2994-2997, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 2994-2997
-
-
Narayan, G.1
Arias-Pulido, H.2
Nandula, S.V.3
Basso, K.4
Sugirtharaj, D.D.5
Vargas, H.6
Mansukhani, M.7
Villella, J.8
Meyer, L.9
Schneider, A.10
Gissmann, L.11
Durst, M.12
Pothuri, B.13
Murty, V.V.14
-
69
-
-
0345073699
-
A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome
-
O'DRISCOLL M, RUIZ-PEREZ VL, WOODS CG, JEGGO PA, GOODSHIP JA: A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome. Nat Genet 33: 497-501, 2003.
-
(2003)
Nat Genet
, vol.33
, pp. 497-501
-
-
O'driscoll, M.1
Ruiz-Perez, V.L.2
Woods, C.G.3
Jeggo, P.A.4
Goodship, J.A.5
-
70
-
-
77952685261
-
Genetic inactivation of the Fanconi anemia gene FANCC identified in the hepatocellular carcinom a cell line HuH-7 confers sensitivity towards DNA-interstrand crossliniking agents
-
PALAGYI A, NEVELING K, PLINNINGER U, ZIESCH A, TARGOSZ BS, DENK GU, OCHS S, RIZZANI A, MEIER D, THASLER WE, HANENBERG H, DE TONI EN, BASSERMANN F, SCHAFER C, GOKE B, SCHINDLER D, GALLMEIER E: Genetic inactivation of the Fanconi anemia gene FANCC identified in the hepatocellular carcinom a cell line HuH-7 confers sensitivity towards DNA-interstrand crossliniking agents. Mol Cancer 9: 127, 2010.
-
(2010)
Mol Cancer
, vol.9
, pp. 127
-
-
Palagyi, A.1
Neveling, K.2
Plinninger, U.3
Ziesch, A.4
Targosz, B.S.5
Denk, G.U.6
Ochs, S.7
Rizzani, A.8
Meier, D.9
Thasler, W.E.10
Hanenberg, H.11
De Toni, E.N.12
Bassermann, F.13
Schafer, C.14
Goke, B.15
Schindler, D.16
Gallmeier, E.17
-
71
-
-
33749465890
-
Cytogenetic instability in ovarian epithelial cells from women at risk of ovarian cancer
-
PEJOVIC T, YATES JE, LIU HY, HAYS LE, AKKARI Y, TORIMARU Y, KEEBLE W, RATHBUN RK, RODGERS WH, BALE AE, AMAZIANE N, ZWAAN CM, ERRAMI A, THUILLIER P, CAPPUCCINI F, OLSON SB, CAIN JM, BAGBY GC Jr: Cytogenetic instability in ovarian epithelial cells from women at risk of ovarian cancer. Cancer Res 66: 9017-9025, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 9017-9025
-
-
Pejovic, T.1
Yates, J.E.2
Liu, H.Y.3
Hays, L.E.4
Akkari, Y.5
Torimaru, Y.6
Keeble, W.7
Rathbun, R.K.8
Rodgers, W.H.9
Bale, A.E.10
Amaziane, N.11
Zwaan, C.M.12
Errami, A.13
Thuillier, P.14
Cappuccini, F.15
Olson, S.B.16
Cain, J.M.17
Bagby Jr., G.C.18
-
72
-
-
33846625493
-
PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene
-
Breast Cancer Susceptibility Collaboration
-
RAHMAN N, SEAL S, THOMPSON D, KELLY P, RENWICK A, ELLIOTT A, REID S, SPANOVA K, BARFOOT R, CHAGTAI T, JAYATILAKE H, MCGUFFOG L, HANKS S, EVANS DG, ECCLES D, BREAST CANCER SUSCEPTIBILITY COLLABORATION, EASTON DF, STRATTON MR: PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene. Nat Genet 39: 165-167, 2007.
-
(2007)
Nat Genet
, vol.39
, pp. 165-167
-
-
Rahman, N.1
Seal, S.2
Thompson, D.3
Kelly, P.4
Renwick, A.5
Elliott, A.6
Reid, S.7
Spanova, K.8
Barfoot, R.9
Chagtai, T.10
Jayatilake, H.11
Mcguffog, L.12
Hanks, S.13
Evans, D.G.14
Eccles, D.15
Easton, D.F.16
Stratton, M.R.17
-
73
-
-
33846569450
-
Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer
-
REID S, SCHINDLER D, HANENBERG H, BARKER K, HANKS S, KALB R, NEVELING K, KELLY P, SEAL S, FREUND M, WURM M, BATISH SD, LACH FP, YETGIN S, NEITZEL H, ARIFFIN H, TISCHKOWITZ M, MATHEW CG, AUERBACH AD, RAHMAN N: Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer. Nat Genet 39: 162-164, 2007.
-
(2007)
Nat Genet
, vol.39
, pp. 162-164
-
-
Reid, S.1
Schindler, D.2
Hanenberg, H.3
Barker, K.4
Hanks, S.5
Kalb, R.6
Neveling, K.7
Kelly, P.8
Seal, S.9
Freund, M.10
Wurm, M.11
Batish, S.D.12
Lach, F.P.13
Yetgin, S.14
Neitzel, H.15
Ariffin, H.16
Tischkowitz, M.17
Mathew, C.G.18
Auerbach, A.D.19
Rahman, N.20
more..
-
74
-
-
0347624597
-
Repair kinetics of genomic interstrand DNA cross-links: evidence for DNA doublestrand break-dependent activation of the Fanconi anemia/BRCA pathway
-
ROTHFUSS A, GROMPE M: Repair kinetics of genomic interstrand DNA cross-links: evidence for DNA doublestrand break-dependent activation of the Fanconi anemia/BRCA pathway. Mol Cell Biol 24: 123-134, 2004.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 123-134
-
-
Rothfuss, A.1
Grompe, M.2
-
75
-
-
33750465216
-
Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles
-
Breast Cancer Susceptibility Collaboration (Uk)
-
SEAL S, THOMPSON D, RENWICK A, ELLIOTT A, KELLY P, BARFOOT R, CHAGTAI T, JAYATILAKE H, AHMED M, SPANOVA K, NORTH B, MCGUFFOG L, EVANS DG, ECCLES D; BREAST CANCER SUSCEPTIBILITY COLLABORATION (UK), EASTON DF, STRATTON MF, RAHMAN N: Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles. Nat Genet 38: 1239-1241, 2006.
-
(2006)
Nat Genet
, vol.38
, pp. 1239-1241
-
-
Seal, S.1
Thompson, D.2
Renwick, A.3
Elliott, A.4
Kelly, P.5
Barfoot, R.6
Chagtai, T.7
Jayatilake, H.8
Ahmed, M.9
Spanova, K.10
North, B.11
Mcguffog, L.12
Evans Dg13
Eccles, D.14
Easton, D.F.15
Stratton, M.F.16
Rahman, N.17
-
76
-
-
0034650849
-
Differentiall toxicities of anticancer agents among DNA repair and checkpoint mutants of Saccharomyces cerevisiae
-
SIMON JA, SZANKASI P, NGUYEN DK, LUDLOW C, DUNSTAN HM, ROBERTS CJ, JENSEN EL, HARTWELL LH, FRIEND SH: Differentiall toxicities of anticancer agents among DNA repair and checkpoint mutants of Saccharomyces cerevisiae. Cancer Res 60: 71-83, 1999.
-
(1999)
Cancer Res
, vol.60
, pp. 71-83
-
-
Simon, J.A.1
Szankasi, P.2
Nguyen, D.K.3
Ludlow, C.4
Dunstan, H.M.5
Roberts, C.J.6
Jensen, E.L.7
Hartwell, L.H.8
Friend, S.H.9
-
77
-
-
79251632658
-
SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype
-
STOEPKER C, HAIN K, SCHUSTER B, HILHORST-HOFSTEE Y, ROOIMANS MA, STELTENPOOL J, OOSTRA AB, EIRICH K, KORTHOF ET, NIEUWINT AW, JASPERS NG, BETTECKEN T, JOENJE H, SCHINDLER D, ROUSE J, DE WINTER JP: SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nat Genet 43: 138-141, 2011.
-
(2011)
Nat Genet
, vol.43
, pp. 138-141
-
-
Stoepker, C.1
Hain, K.2
Schuster, B.3
Hilhorst-Hofstee, Y.4
Rooimans, M.A.5
Steltenpool, J.6
Oostra, A.B.7
Eirich, K.8
Korthof, E.T.9
Nieuwint, A.W.10
Jaspers, N.G.11
Bettecken, T.12
Joenje, H.13
Schindler, D.14
Rouse, J.15
De Winter, J.P.16
-
78
-
-
33744481750
-
Molecular pathogenesis of Fanconi anemia: recent progress
-
TANIGUCHI T, D'ANDREA AD: Molecular pathogenesis of Fanconi anemia: recent progress. Blood 107: 4223-4233, 2006.
-
(2006)
Blood
, vol.107
, pp. 4223-4233
-
-
Taniguchi, T.1
D'Andrea, A.D.2
-
79
-
-
0038075462
-
Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors
-
TANIGUCHI T, TISCHKOWITZ M, AMEZIANE N, HODGSON SV, MATHEW CG, JOENJE H, MOK SC, D'ANDREA AD: Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nat Med 9: 568-574, 2003.
-
(2003)
Nat Med
, vol.9
, pp. 568-574
-
-
Taniguchi, T.1
Tischkowitz, M.2
Ameziane, N.3
Hodgson, S.V.4
Mathew, C.G.5
Joenje, H.6
Mok, S.C.7
D'Andrea, A.D.8
-
80
-
-
69349092943
-
Analysis of the gene coding for the BRCA2-interacting protein PALB2 in familial and sporadic pancreatic cancer
-
TISCHKOWITZ MD, SABBAGHIAN N, HAMEL N, BORGIDA A, ROSNER C, TAHERIAN N, SRIVASTAVA A, HOLTER S, ROTHENMUND H, GHADIRIAN P, FOULES WD, GALLINGER: Analysis of the gene coding for the BRCA2-interacting protein PALB2 in familial and sporadic pancreatic cancer. Gastroenterology 137: 1183-1186, 2009.
-
(2009)
Gastroenterology
, vol.137
, pp. 1183-1186
-
-
Tischkowitz, M.D.1
Sabbaghian, N.2
Hamel, N.3
Borgida, A.4
Rosner, C.5
Taherian, N.6
Srivastava, A.7
Holter, S.8
Rothenmund, H.9
Ghadirian, P.10
Foules, W.D.11
Gallinger12
-
81
-
-
0034795339
-
Use of isogenic human cancer cells for highthroughput screening and drug discovery
-
TORRANCE CJ, AGRAWAL V, VOGELSTEIN B, KINZLER KW: Use of isogenic human cancer cells for highthroughput screening and drug discovery. Nat Biotechnol 19: 940-945, 2001.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 940-945
-
-
Torrance, C.J.1
Agrawal, V.2
Vogelstein, B.3
Kinzler, K.W.4
-
82
-
-
0035801472
-
Mutation in BRCA2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences
-
TUTT A, BERTWISTLE D, VALENTINE J, GABRIEL A, SWIFT S, ROSS G, GRIFFIN C, THACKER J, ASHWORTH A: Mutation in BRCA2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences. EMBO J 20: 4704-4716, 2001.
-
(2001)
EMBO J
, vol.20
, pp. 4704-4716
-
-
Tutt, A.1
Bertwistle, D.2
Valentine, J.3
Gabriel, A.4
Swift, S.5
Ross, G.6
Griffin, C.7
Thacker, J.8
Ashworth, A.9
-
83
-
-
3242789247
-
Functional defects in the fanconi anemia pathway in pancreatic cancer cells
-
VAN DER HEIJDEN MS, BRODY JR, GALLMEIER E, CUNNINGHAM SC, DEZENTJE DA, SHEN D, HRUBAN RH, KERN SE: Functional defects in the fanconi anemia pathway in pancreatic cancer cells. Am J Pathol 165: 651-657, 2004.
-
(2004)
Am J Pathol
, vol.165
, pp. 651-657
-
-
Van Der Heijden, M.S.1
Brody, J.R.2
Gallmeier, E.3
Cunningham, S.C.4
Dezentje, D.A.5
Shen, D.6
Hruban, R.H.7
Kern, S.E.8
-
84
-
-
0037505830
-
Fanconi anemia gene mutations in young-onset pancreatic cancer
-
VAN DER HEIJDEN MS, YEO CJ, HRUBAN RH, KERN SE: Fanconi anemia gene mutations in young-onset pancreatic cancer. Cancer Res 63: 2585-2588, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 2585-2588
-
-
Van der Heijden, M.S.1
Yeo, C.J.2
Hruban, R.H.3
Kern, S.E.4
-
85
-
-
4444279075
-
Gene interactions in the DNA damage-response pathway identified by genome-wide RNA-interference analysis of synthetic lethality
-
VAN HAAFTEN G, VASTENHOUW NL, NOLLEN EAA, PLASTERK RHA, TIJSTERMAN M: Gene interactions in the DNA damage-response pathway identified by genome-wide RNA-interference analysis of synthetic lethality. Proc Natl Acad Sci U S A 101: 12992-12996, 2004.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 12992-12996
-
-
Van Haaften, G.1
Vastenhouw, N.L.2
Nollen, E.A.A.3
Plasterk, R.H.A.4
Tijsterman, M.5
-
86
-
-
7244234131
-
Androgens and liver tumors: Fanconi's anemia and non-Fanconi's conditions
-
VELAZQUEZ I, ALTER BP: Androgens and liver tumors: Fanconi's anemia and non-Fanconi's conditions. Am J Hematol 77: 257-267, 2004.
-
(2004)
Am J Hematol
, vol.77
, pp. 257-267
-
-
Velazquez, I.1
Alter, B.P.2
-
87
-
-
4043181214
-
Cancer gees ad the pathways they control
-
VOGELSTEIN B, KIZLER KW: Cancer gees ad the pathways they control. Nat Med 10: 789-799, 2004.
-
(2004)
Nat Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kizler, K.W.2
-
88
-
-
9144273977
-
RNAi and HTS: exploring cancer by systematic loss-of-function
-
WILLINGHAM AT, DEVERAUX QL, HAMPTON GM, AZA-BLANC P: RNAi and HTS: exploring cancer by systematic loss-of-function. Oncogene 23: 8392-8400, 2004.
-
(2004)
Oncogene
, vol.23
, pp. 8392-8400
-
-
Willingham, A.T.1
Deveraux, Q.L.2
Hampton, G.M.3
Aza-Blanc, P.4
-
89
-
-
33846601829
-
Fanconi anemia is associated with a defect in the BRCA2 partner PALB2
-
XIA B, DORSMAN JC, AMEZIANE N, DE VRIES Y, ROOIMANS MA, SHENG Q, PALS G, ERRAMI A, GLUCKMAN E, LLERA J, WANG W, LIVINGSTON DM, JOENJE H, DE WINTER JP: Fanconi anemia is associated with a defect in the BRCA2 partner PALB2. Nat Genet 39: 159-161, 2007.
-
(2007)
Nat Genet
, vol.39
, pp. 159-161
-
-
Xia, B.1
Dorsman Jc2
Ameziane, N.3
De Vries, Y.4
Rooimans Ma5
Sheng, Q.6
Pals, G.7
Errami, A.8
Gluckman, E.9
Llera, J.10
Wang, W.11
Livingston, D.M.12
Joenje, H.13
De Winter, J.P.14
-
90
-
-
0034486838
-
Aberrant Fanconi Anaemia protein profiles in acute myeloid leukamia cells
-
XIE Y, DE WINTER JP, WAISFISZ Q, NIEUWINT AW, SCHEPER RJ, ARWERT F, HOATLIN ME, OSSENKOPPELE GJ, SCHUURHUIS GJ, JOENJE H: Aberrant Fanconi Anaemia protein profiles in acute myeloid leukamia cells. Br J Haematol 111: 1057-1064, 2000.
-
(2000)
Br J Haematol
, vol.111
, pp. 1057-1064
-
-
Xie, Y.1
De Winter, J.P.2
Waisfisz, Q.3
Nieuwint, A.W.4
Scheper, R.J.5
Arwert, F.6
Hoatlin, M.E.7
Ossenkoppele, G.J.8
Schuurhuis, G.J.9
Joenje, H.10
-
91
-
-
18544372595
-
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
-
YANG H, JEFFREY PD, MILLER J, KINNUCAN E, SUN Y, THOMA NH, ZHENG N, CHEN PL, LEE WH, PAVLETICH NP: BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure. Science 297: 1837-1848, 2002.
-
(2002)
Science
, vol.297
, pp. 1837-1848
-
-
Yang, H.1
Jeffrey, P.D.2
Miller, J.3
Kinnucan, E.4
Sun, Y.5
Thoma, N.H.6
Zheng, N.7
Chen, P.L.8
Lee, W.H.9
Pavletich, N.P.10
-
92
-
-
0037223410
-
Nucleotide excision repairand polymerase η-mediated error-prone removal of mitomycin C interstand cross-links
-
ZHENG H, WANG X, WARREN AJ, LEGERSKI RJ, NAIRN RS, HAMILTON JW, LI L: Nucleotide excision repairand polymerase η-mediated error-prone removal of mitomycin C interstand cross-links. Mol Cell Biol 23: 754-761, 2003.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 754-761
-
-
Zheng, H.1
Wang, X.2
Warren, A.J.3
Legerski, R.J.4
Nairn, R.S.5
Hamilton, J.W.6
Li, L.7
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