Absence of specific cell killing of the BRCA2-deficient human cancer cell line CAPAN1 by poly(ADP-ribose) polymerase inhibition

Cancer Biology and Therapy

Volumn 4, Issue 7, 2005, Pages 703-706

  Gallmeier, Eike ^a   Kern, Scott E ^a,b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

BRCA2; Breast cancer; CAPAN1; Pancreatic cancer; PARP inhibition; Poly(ADP ribose) polymerase; Selective cell killing

Indexed keywords

8 HYDROXY 2 METHYL 4(3H) QUINAZOLINONE; BRCA2 PROTEIN; CYTOTOXIC AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR;

CANCER CELL CULTURE; CANCER CELL DESTRUCTION; CANCER CHEMOTHERAPY; CELL KILLING; CLONOGENIC ASSAY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; FRAMESHIFT MUTATION; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; SHORT SURVEY; STATISTICAL SIGNIFICANCE;

EID: 25144432400     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.4.7.1909     Document Type: Short Survey

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