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We regret the omission of key references; in many cases we have listed recent reviews for brevity. We thank B. Thornton and J. Kroll for the communication of unpublished results; L. Streichert for comments on the manuscript; and R. Klausner for encouragement. Supported by National Cancer Institute (NCI) grant NO1-BC65017 to the NCI Field Station at the Seattle Project, and a grant from Merck Company.
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