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Volumn 95, Issue 3, 2003, Pages 214-221

BRCA2 germline mutations in familial pancreatic carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

BRCA2 PROTEIN; GENOMIC DNA; MUTANT PROTEIN;

EID: 0037420026     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/95.3.214     Document Type: Article
Times cited : (423)

References (39)
  • 2
    • 0034901004 scopus 로고    scopus 로고
    • Increased risk of incident pancreatic cancer among first-degree relatives of patients with familial pancreatic cancer
    • Tersmette AC, Petersen GM, Offerhaus GJ, Falatko FC, Brune KA, Goggins M, et al. Increased risk of incident pancreatic cancer among first-degree relatives of patients with familial pancreatic cancer. Clin Cancer Res 2001;7:738-44.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 738-744
    • Tersmette, A.C.1    Petersen, G.M.2    Offerhaus, G.J.3    Falatko, F.C.4    Brune, K.A.5    Goggins, M.6
  • 3
    • 0032797516 scopus 로고    scopus 로고
    • Diabetes mellitus, other medical conditions and familial history of cancer as risk factors for pancreatic cancer
    • Silverman DT, Schiffman M, Everhart J, Goldstein A, Lillemoe KD, Swanson GM, et al. Diabetes mellitus, other medical conditions and familial history of cancer as risk factors for pancreatic cancer. Br J Cancer 1999; 80:1830-7.
    • (1999) Br. J. Cancer , vol.80 , pp. 1830-1837
    • Silverman, D.T.1    Schiffman, M.2    Everhart, J.3    Goldstein, A.4    Lillemoe, K.D.5    Swanson, G.M.6
  • 4
    • 0031950026 scopus 로고    scopus 로고
    • Recent discoveries in cancer genetics of exocrine pancreatic neoplasia
    • Hahn SA, Schmiegel WH. Recent discoveries in cancer genetics of exocrine pancreatic neoplasia. Digestion 1998;59:493-501.
    • (1998) Digestion , vol.59 , pp. 493-501
    • Hahn, S.A.1    Schmiegel, W.H.2
  • 7
    • 0025963801 scopus 로고
    • Pancreatic cancer and the familial atypical multiple mole melanoma (FAMMM) syndrome
    • Lynch HT, Fusaro RM. Pancreatic cancer and the familial atypical multiple mole melanoma (FAMMM) syndrome. Pancreas 1991;6:127-31.
    • (1991) Pancreas , vol.6 , pp. 127-131
    • Lynch, H.T.1    Fusaro, R.M.2
  • 12
    • 0027248156 scopus 로고
    • Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: An updated review
    • Lynch HT, Smyrk TC, Watson P, Lanspa SJ, Lynch JF, Lynch PM, et al. Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review. Gastroenterology 1993; 104:1535-49.
    • (1993) Gastroenterology , vol.104 , pp. 1535-1549
    • Lynch, H.T.1    Smyrk, T.C.2    Watson, P.3    Lanspa, S.J.4    Lynch, J.F.5    Lynch, P.M.6
  • 15
    • 0029102927 scopus 로고
    • A familial syndrome of pancreatic carcinoma and melanoma with a mutation in the CDKN2 tumor suppressor gene
    • Whelan AJ, Bartsch D, Goodfellow PJ. A familial syndrome of pancreatic carcinoma and melanoma with a mutation in the CDKN2 tumor suppressor gene. N Engl J Med 1995;333:975-7.
    • (1995) N. Engl. J. Med. , vol.333 , pp. 975-977
    • Whelan, A.J.1    Bartsch, D.2    Goodfellow, P.J.3
  • 16
    • 0028059330 scopus 로고
    • Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma
    • Caldas C, Hahn SA, da Costa LT, Redston MS, Schutte M, Seymour AB, et al. Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma. Nat Genet 1994;8:27-32.
    • (1994) Nat. Genet. , vol.8 , pp. 27-32
    • Caldas, C.1    Hahn, S.A.2    da Costa, L.T.3    Redston, M.S.4    Schutte, M.5    Seymour, A.B.6
  • 18
    • 0031974516 scopus 로고    scopus 로고
    • Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase
    • Jenne DE, Reimann H, Nezu J, Friedel W, Loff S, Jeschke R, et al. Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase. Nat Genet 1998;18:38-43.
    • (1998) Nat. Genet. , vol.18 , pp. 38-43
    • Jenne, D.E.1    Reimann, H.2    Nezu, J.3    Friedel, W.4    Loff, S.5    Jeschke, R.6
  • 19
    • 0032984141 scopus 로고    scopus 로고
    • Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers
    • Su GH, Hruban RH, Bansal RK, Bova GS, Tang DJ, Shekher MC, et al. Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers. Am J Pathol 1999;154:1835-40.
    • (1999) Am. J. Pathol. , vol.154 , pp. 1835-1840
    • Su, G.H.1    Hruban, R.H.2    Bansal, R.K.3    Bova, G.S.4    Tang, D.J.5    Shekher, M.C.6
  • 20
    • 0029041032 scopus 로고
    • Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region
    • Schutte M, da Costa LT, Hahn SA, Moskaluk C, Hoque AT, Rozenblum E, et al. Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region. Proc Natl Acad Sci U S A 1995;92:5950-4.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 5950-5954
    • Schutte, M.1    da Costa, L.T.2    Hahn, S.A.3    Moskaluk, C.4    Hoque, A.T.5    Rozenblum, E.6
  • 21
    • 12644253827 scopus 로고    scopus 로고
    • Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas
    • Goggins M, Schutte M, Lu J, Moskaluk CA, Weinstein CL, Peterson GM, et al. Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas. Cancer Res 1996;56:5360-4.
    • (1996) Cancer Res. , vol.56 , pp. 5360-5364
    • Goggins, M.1    Schutte, M.2    Lu, J.3    Moskaluk, C.A.4    Weinstein, C.L.5    Peterson, G.M.6
  • 23
    • 16044366988 scopus 로고    scopus 로고
    • The carrier frequency of the BRCA26174delT mutation among Ashkenazi Jewish individuals is approximately 1%
    • Oddoux C, Struewing JP, Clayton CM, Neuhausen S, Brody LC, Kaback M, et al. The carrier frequency of the BRCA26174delT mutation among Ashkenazi Jewish individuals is approximately 1%. Nat Genet 1996;14: 188-90.
    • (1996) Nat. Genet. , vol.14 , pp. 188-190
    • Oddoux, C.1    Struewing, J.P.2    Clayton, C.M.3    Neuhausen, S.4    Brody, L.C.5    Kaback, M.6
  • 24
    • 0034650411 scopus 로고    scopus 로고
    • Inherited predisposition to pancreatic adenocarcinoma: Role of family history and germ-line p16, BRCA1, and BRCA2 mutations
    • Lal G, Liu G, Schmocker B, Kaurah P, Ozcelik H, Narod SA, et al. Inherited predisposition to pancreatic adenocarcinoma: role of family history and germ-line p16, BRCA1, and BRCA2 mutations. Cancer Res 2000; 60:409-16.
    • (2000) Cancer Res. , vol.60 , pp. 409-416
    • Lal, G.1    Liu, G.2    Schmocker, B.3    Kaurah, P.4    Ozcelik, H.5    Narod, S.A.6
  • 25
    • 0035283898 scopus 로고    scopus 로고
    • A BRCA2 germ-line mutation in familial pancreatic carcinoma
    • White K, Held KR, Weber BH. A BRCA2 germ-line mutation in familial pancreatic carcinoma. Int J Cancer 2001;91:742-4.
    • (2001) Int. J. Cancer , vol.91 , pp. 742-744
    • White, K.1    Held, K.R.2    Weber, B.H.3
  • 26
    • 0036644884 scopus 로고    scopus 로고
    • Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: Deleterious BRCA2 mutations in 17%
    • Murphy KM, Brune KA, Griffin C, Sollenberger JE, Petersen GM, Bansal R, et al. Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17%. Cancer Res 2002;62:3789-93.
    • (2002) Cancer Res. , vol.62 , pp. 3789-3793
    • Murphy, K.M.1    Brune, K.A.2    Griffin, C.3    Sollenberger, J.E.4    Petersen, G.M.5    Bansal, R.6
  • 28
    • 0036269812 scopus 로고    scopus 로고
    • Familial pancreatic cancer-concept for study of the National Case Collection and early diagnosis program for high risk people
    • Gerdes B, Kress R, Rieder H, Sina-Frey M, Przypadlo E, Barth P, et al. Familial pancreatic cancer-concept for study of the National Case Collection and early diagnosis program for high risk people. Z Arztl Fortbild Qualitatssich 2002;96:251-5.
    • (2002) Z. Arztl. Fortbild. Qualitatssich , vol.96 , pp. 251-255
    • Gerdes, B.1    Kress, R.2    Rieder, H.3    Sina-Frey, M.4    Przypadlo, E.5    Barth, P.6
  • 29
    • 0034043609 scopus 로고    scopus 로고
    • Genetic testing. Counseling, laboratory, and regulatory issues and the EUROPAC protocol for ethical research in multicenter studies of inherited pancreatic diseases
    • Applebaum SE, Kant JA, Whitcomb DC, Ellis IH. Genetic testing. Counseling, laboratory, and regulatory issues and the EUROPAC protocol for ethical research in multicenter studies of inherited pancreatic diseases. Med Clin North Am 2000;84:575-88.
    • (2000) Med. Clin. North Am. , vol.84 , pp. 575-588
    • Applebaum, S.E.1    Kant, J.A.2    Whitcomb, D.C.3    Ellis, I.H.4
  • 30
    • 0034767957 scopus 로고    scopus 로고
    • Cancer burden in the year 2000. The global picture
    • Parkin DM, Bray FI, Devesa SS. Cancer burden in the year 2000. The global picture. Eur J Cancer 2001;37 Suppl 8:S4-66.
    • (2001) Eur. J. Cancer , vol.37 , Issue.SUPPL. 8
    • Parkin, D.M.1    Bray, F.I.2    Devesa, S.S.3
  • 32
    • 0036466858 scopus 로고    scopus 로고
    • Comprehensive analysis of 989 patients with breast or ovarian cancer provides BRCA1 and BRCA2 mutation profiles and frequencies for the German population
    • Meindl A. Comprehensive analysis of 989 patients with breast or ovarian cancer provides BRCA1 and BRCA2 mutation profiles and frequencies for the German population. Int J Cancer 2002;97:472-80.
    • (2002) Int. J. Cancer , vol.97 , pp. 472-480
    • Meindl, A.1
  • 34
    • 0033842724 scopus 로고    scopus 로고
    • BRCA2 is inactivated late in the development of pancreatic intraepithelial neoplasia: Evidence and implications
    • Goggins M, Hruban RH, Kern SE. BRCA2 is inactivated late in the development of pancreatic intraepithelial neoplasia: evidence and implications. Am J Pathol 2000;156:1767-71.
    • (2000) Am. J. Pathol. , vol.156 , pp. 1767-1771
    • Goggins, M.1    Hruban, R.H.2    Kern, S.E.3
  • 35
    • 0030932869 scopus 로고    scopus 로고
    • Cancer-susceptibility genes. Gatekeepers and caretakers
    • Kinzler KW, Vogelstein B. Cancer-susceptibility genes. Gatekeepers and caretakers. Nature 1997;386:761, 763.
    • (1997) Nature , vol.386 , pp. 761-763
    • Kinzler, K.W.1    Vogelstein, B.2
  • 36
    • 0037169354 scopus 로고    scopus 로고
    • Cancer susceptibility and the functions of BRCA1 and BRCA2
    • Venkitaraman AR. Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 2002;108:171-82.
    • (2002) Cell , vol.108 , pp. 171-182
    • Venkitaraman, A.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.