Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene

Science

Volumn 324, Issue 5924, 2009, Pages 217-

  Jones, Siân ^a,b   Hruban, Ralph H ^b   Kamiyama, Mihoko ^b   Borges, Michael ^b   Zhang, Xiaosong ^a,b   Parsons, D Williams ^a,b   Lin, Jimmy Cheng Ho ^a,b   Palmisano, Emily ^b   Brune, Kieran ^b   Jaffee, Elizabeth M ^b   Iacobuzio Donahue, Christine A ^b   Maitra, Anirban ^b   Parmigiani, Giovanni ^b   Kern, Scott E ^b   Velculescu, Victor E ^a   Kinzler, Kenneth W ^a   Vogelstein, Bert ^a,b   Eshleman, James R ^b   Goggins, Michael ^b   Klein, Alison P ^b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA2 PROTEIN;

CANCER; DNA; GENE EXPRESSION; GENOME; IDENTIFICATION METHOD; MUTATION; PROTEIN; TUMOR;

AGED; ARTICLE; BREAST CANCER; CARCINOGENESIS; CONTROLLED STUDY; EXON; FAMILIAL CANCER; GENE; GENE DELETION; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; PALB2 GENE; PANCREAS CANCER; PRIORITY JOURNAL;

BREAST NEOPLASMS; CODON, TERMINATOR; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HUMANS; MALE; NUCLEAR PROTEINS; PANCREATIC NEOPLASMS; PEDIGREE; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION; TUMOR SUPPRESSOR PROTEINS;

EID: 64849092309     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1171202     Document Type: Article

References (10)

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10. Supported by the Sol Goldman Pancreatic Cancer Research Center; the Lustgarten Foundation for Pancreatic Cancer Research; the Virginia and D. K. Ludwig Fund for Cancer Research; NIH grants CA62924, CA123483, and RO1CA97075; and the Michael Rolfe Pancreatic Cancer Foundation.