Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 9, 2009, Pages 3276-3281

  McManus, Kirk J ^a   Barrett, Irene J ^a   Nouhi, Yasaman ^a   Hieter, Philip ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Cancer therapeutics; Chromosome instability; Synthetic lethality

Indexed keywords

FLAP ENDONUCLEASE; FUNGAL PROTEIN; PROTEIN FEN1; PROTEIN RAD27; RAD54 PROTEIN; RAD54B PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CHROMOSOMAL INSTABILITY; COLORECTAL CANCER; CONTROLLED STUDY; CYTOTOXICITY; GENE INTERACTION; GENE MUTATION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; MICROSCOPY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE CULTURE;

APOPTOSIS; CHROMOSOMAL INSTABILITY; COLORECTAL NEOPLASMS; DNA HELICASES; FLAP ENDONUCLEASES; GENE SILENCING; HUMANS; NUCLEAR PROTEINS; PHENOTYPE; SUBSTRATE SPECIFICITY; TISSUE CULTURE TECHNIQUES;

MAMMALIA;

EID: 62549124623     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0813414106     Document Type: Article

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