-
1
-
-
18444362122
-
Biallelic inactivation of BRCA2 in Fanconi anemia
-
Howlett NG, Taniguchi T, Olson S, Cox B, Waisfisz Q, De Die-Smulders C, Persky N, Grompe M, Joenje H, Pals G, Ikeda H, Fox EA, D'Andrea AD: Biallelic inactivation of BRCA2 in Fanconi anemia. Science 2002, 297:606-609
-
(2002)
Science
, vol.297
, pp. 606-609
-
-
Howlett, N.G.1
Taniguchi, T.2
Olson, S.3
Cox, B.4
Waisfisz, Q.5
De Die-Smulders, C.6
Persky, N.7
Grompe, M.8
Joenje, H.9
Pals, G.10
Ikeda, H.11
Fox, E.A.12
D'Andrea, A.D.13
-
2
-
-
12644253827
-
Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas
-
Goggins M, Schutte M, Lu J, Moskaluk CA, Weinstein CL, Petersen GM, Yeo CJ, Jackson CE, Lynch HT, Hruban RH, Kern SE: Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas. Cancer Res 1996, 56:5360-5364
-
(1996)
Cancer Res
, vol.56
, pp. 5360-5364
-
-
Goggins, M.1
Schutte, M.2
Lu, J.3
Moskaluk, C.A.4
Weinstein, C.L.5
Petersen, G.M.6
Yeo, C.J.7
Jackson, C.E.8
Lynch, H.T.9
Hruban, R.H.10
Kern, S.E.11
-
3
-
-
0036644884
-
Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: Deleterious BRCA2 mutations in 17%
-
Murphy KM, Brune KA, Griffin C, Sollenberger JE, Petersen GM, Bansal R, Hruban RH, Kern SE: Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17%. Cancer Res 2002, 62:3789-3793
-
(2002)
Cancer Res
, vol.62
, pp. 3789-3793
-
-
Murphy, K.M.1
Brune, K.A.2
Griffin, C.3
Sollenberger, J.E.4
Petersen, G.M.5
Bansal, R.6
Hruban, R.H.7
Kern, S.E.8
-
4
-
-
0035099690
-
The rate of the 6174delT founder Jewish mutation in BRCA2 in patients with non-colonic gastrointestinal tract tumours in Israel
-
Figer A, Irmin L, Geva R, Flex D, Sulkes J, Sulkes A, Friedman E: The rate of the 6174delT founder Jewish mutation in BRCA2 in patients with non-colonic gastrointestinal tract tumours in Israel. Br J Cancer 2001, 84:478-481
-
(2001)
Br J Cancer
, vol.84
, pp. 478-481
-
-
Figer, A.1
Irmin, L.2
Geva, R.3
Flex, D.4
Sulkes, J.5
Sulkes, A.6
Friedman, E.7
-
5
-
-
0037420026
-
BRCA2 germline mutations in familial pancreatic carcinoma
-
Hahn SA, Greenhalf B, Ellis I, Sina-Frey M, Rieder H, Korte B, Gerdes B, Kress R, Ziegler A, Raeburn JA, Campra D, Grutzmann R. Rehder H, Rothmund M, Schmiegel W, Neoptolemos JP, Bartsch DK: BRCA2 germline mutations in familial pancreatic carcinoma. J Natl Cancer Inst 2003, 95:214-221
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 214-221
-
-
Hahn, S.A.1
Greenhalf, B.2
Ellis, I.3
Sina-Frey, M.4
Rieder, H.5
Korte, B.6
Gerdes, B.7
Kress, R.8
Ziegler, A.9
Raeburn, J.A.10
Campra, D.11
Grutzmann, R.12
Rehder, H.13
Rothmund, M.14
Schmiegel, W.15
Neoptolemos, J.P.16
Bartsch, D.K.17
-
6
-
-
0037505830
-
Fanconi anemia gene mutations in young-onset pancreatic cancer
-
van der Heijden MS, Yeo CJ, Hruban RH, Kern SE: Fanconi anemia gene mutations in young-onset pancreatic cancer. Cancer Res 2003, 63:2585-2588
-
(2003)
Cancer Res
, vol.63
, pp. 2585-2588
-
-
Van Der Heijden, M.S.1
Yeo, C.J.2
Hruban, R.H.3
Kern, S.E.4
-
7
-
-
0033503579
-
Complete clinical remission in a patient with advanced pancreatic cancer using mitomycin C-based chemotherapy: The role of adjunctive heparin
-
Sadoff L, Latino F: Complete clinical remission in a patient with advanced pancreatic cancer using mitomycin C-based chemotherapy: the role of adjunctive heparin. Am J Clin Oncol 1999, 22:187-190
-
(1999)
Am J Clin Oncol
, vol.22
, pp. 187-190
-
-
Sadoff, L.1
Latino, F.2
-
8
-
-
0032415443
-
Prospective randomized trial of 5-fluorouracil, doxorubicin, and mitomycin C for non-resectable pancreatic and biliary carcinoma: Multicenter randomized trial
-
Takada T, Nimura Y, Katoh H, Nagakawa T, Nakayama T, Matsushiro T, Amano H, Wada K: Prospective randomized trial of 5-fluorouracil, doxorubicin, and mitomycin C for non-resectable pancreatic and biliary carcinoma: multicenter randomized trial. Hepatogastroenterology 1998, 45:2020-2026
-
(1998)
Hepatogastroenterology
, vol.45
, pp. 2020-2026
-
-
Takada, T.1
Nimura, Y.2
Katoh, H.3
Nagakawa, T.4
Nakayama, T.5
Matsushiro, T.6
Amano, H.7
Wada, K.8
-
9
-
-
0032009833
-
Resection of locally advanced pancreatic cancer after downstaging with continuous-infusion 5-fluorouracil, mitomycin-C, leucovorin, and dipyridamole
-
Todd KE, Gloor B, Lane JS, Isacoff WH, Reber HA: Resection of locally advanced pancreatic cancer after downstaging with continuous-infusion 5-fluorouracil, mitomycin-C, leucovorin, and dipyridamole. J Gastrointest Surg 1998, 2:159-166
-
(1998)
J Gastrointest Surg
, vol.2
, pp. 159-166
-
-
Todd, K.E.1
Gloor, B.2
Lane, J.S.3
Isacoff, W.H.4
Reber, H.A.5
-
10
-
-
0035874894
-
Homology-directed DNA repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brcal mutation
-
Moynahan ME, Cui TY, Jasin M: Homology-directed DNA repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brcal mutation. Cancer Res 2001, 61:4842-4850
-
(2001)
Cancer Res
, vol.61
, pp. 4842-4850
-
-
Moynahan, M.E.1
Cui, T.Y.2
Jasin, M.3
-
11
-
-
0032126029
-
Double-strand break repair deficiency and radiation sensitivity in BRCA2 mutant cancer cells
-
Abbott DW, Freeman ML, Holt JT: Double-strand break repair deficiency and radiation sensitivity in BRCA2 mutant cancer cells. J Natl Cancer Inst 1998, 90:978-985
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 978-985
-
-
Abbott, D.W.1
Freeman, M.L.2
Holt, J.T.3
-
12
-
-
0032574733
-
The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment
-
Chen PL, Chen CF, Chen Y, Xiao J, Sharp ZD, Lee WH: The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment. Proc Natl Acad Sci USA 1998, 95:5287-5292
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 5287-5292
-
-
Chen, P.L.1
Chen, C.F.2
Chen, Y.3
Xiao, J.4
Sharp, Z.D.5
Lee, W.H.6
-
13
-
-
0028059330
-
Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma
-
Caldas C, Hahn SA, da Costa LT, Redston MS, Schutte M, Seymour AB, Weinstein CL, Hruban RH, Yeo CJ, Kern SE: Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma. Nat Genet 1994, 8:27-32
-
(1994)
Nat Genet
, vol.8
, pp. 27-32
-
-
Caldas, C.1
Hahn, S.A.2
Da Costa, L.T.3
Redston, M.S.4
Schutte, M.5
Seymour, A.B.6
Weinstein, C.L.7
Hruban, R.H.8
Yeo, C.J.9
Kern, S.E.10
-
14
-
-
0028875562
-
Allelotype of pancreatic adenocarcinoma using xenograft enrichment
-
Hahn SA, Seymour AB, Hoque AT, Schutte M. da Costa LT, Redston MS, Caldas C, Weinstein CL, Fischer A, Yeo CJ, Hruban RH, Kern SE: Allelotype of pancreatic adenocarcinoma using xenograft enrichment. Cancer Res 1995, 55:4670-4675
-
(1995)
Cancer Res
, vol.55
, pp. 4670-4675
-
-
Hahn, S.A.1
Seymour, A.B.2
Hoque, A.T.3
Schutte, M.4
Da Costa, L.T.5
Redston, M.S.6
Caldas, C.7
Weinstein, C.L.8
Fischer, A.9
Yeo, C.J.10
Hruban, R.H.11
Kern, S.E.12
-
15
-
-
0029862497
-
A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes
-
Ory DS, Neugeboren BA, Mulligan RC: A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes. Proc Natl Acad Sci USA 1996, 93:11400-11406
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11400-11406
-
-
Ory, D.S.1
Neugeboren, B.A.2
Mulligan, R.C.3
-
16
-
-
0033000911
-
Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex
-
Garcia-Higuera I, Kuang Y, Naf D, Wasik J, D'Andrea AD: Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex. Mol Cell Biol 1999, 19:4866-4873
-
(1999)
Mol Cell Biol
, vol.19
, pp. 4866-4873
-
-
Garcia-Higuera, I.1
Kuang, Y.2
Naf, D.3
Wasik, J.4
D'Andrea, A.D.5
-
17
-
-
0034283708
-
Carboxy terminal region of the Fanconi anemia protein, FANCG/XRCC9, is required for functional activity
-
Kuang Y, Garcia-Higuera I, Moran A, Mondoux M, Digweed M, D'Andrea AD: Carboxy terminal region of the Fanconi anemia protein, FANCG/XRCC9, is required for functional activity. Blood 2000, 96:1625-1632
-
(2000)
Blood
, vol.96
, pp. 1625-1632
-
-
Kuang, Y.1
Garcia-Higuera, I.2
Moran, A.3
Mondoux, M.4
Digweed, M.5
D'Andrea, A.D.6
-
18
-
-
0031657241
-
Functional activity of the Fanconi anemia protein FAA requires FAC binding and nuclear localization
-
Naf D, Kupfer GM, Suliman A, Lambert K, D'Andrea AD: Functional activity of the Fanconi anemia protein FAA requires FAC binding and nuclear localization. Mol Cell Biol 1998, 18:5952-5960
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5952-5960
-
-
Naf, D.1
Kupfer, G.M.2
Suliman, A.3
Lambert, K.4
D'Andrea, A.D.5
-
19
-
-
0141484612
-
A novel ubiquitin ligase is deficient in Fanconi anemia
-
Meetei AR, de Winter JP, Medhurst AL, Wallisch M, Waisfisz Q, van de Vrugt HJ, Oostra AB, Yan Z, Ling C, Bishop CE, Hoatlin ME, Joenje H, Wang W: A novel ubiquitin ligase is deficient in Fanconi anemia. Nat Genet 2003, 35:165-170
-
(2003)
Nat Genet
, vol.35
, pp. 165-170
-
-
Meetei, A.R.1
De Winter, J.P.2
Medhurst, A.L.3
Wallisch, M.4
Waisfisz, Q.5
Van De Vrugt, H.J.6
Oostra, A.B.7
Yan, Z.8
Ling, C.9
Bishop, C.E.10
Hoatlin, M.E.11
Joenje, H.12
Wang, W.13
-
20
-
-
0037328823
-
Regulation of the Fanconi anemia pathway by monoubiquitination
-
Gregory RC, Taniguchi T, D'Andrea AD: Regulation of the Fanconi anemia pathway by monoubiquitination. Semin Cancer Biol 2003, 13:77-82
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 77-82
-
-
Gregory, R.C.1
Taniguchi, T.2
D'Andrea, A.D.3
-
22
-
-
0035099044
-
BRCA2 is required for homology-directed repair of chromosomal breaks
-
Moynahan ME, Pierce AJ, Jasin M: BRCA2 is required for homology-directed repair of chromosomal breaks. Mol Cell 2001, 7:263-272
-
(2001)
Mol Cell
, vol.7
, pp. 263-272
-
-
Moynahan, M.E.1
Pierce, A.J.2
Jasin, M.3
-
23
-
-
0015891353
-
A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents
-
Sasaki MS, Tonomura A: A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents. Cancer Res 1973, 33:1829-1836
-
(1973)
Cancer Res
, vol.33
, pp. 1829-1836
-
-
Sasaki, M.S.1
Tonomura, A.2
-
24
-
-
0017118656
-
Susceptibility of Fanconi's anaemia fibroblasts to chromosome damage by carcinogens
-
Auerbach AD, Wolman SR: Susceptibility of Fanconi's anaemia fibroblasts to chromosome damage by carcinogens. Nature 1976, 261:494-496
-
(1976)
Nature
, vol.261
, pp. 494-496
-
-
Auerbach, A.D.1
Wolman, S.R.2
-
25
-
-
0035801472
-
Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences
-
Tutt A, Bertwistle D, Valentine J, Gabriel A, Swift S, Ross G, Griffin C, Thacker J, Ashworth A: Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences. EMBO J 2001, 20:4704-4716
-
(2001)
EMBO J
, vol.20
, pp. 4704-4716
-
-
Tutt, A.1
Bertwistle, D.2
Valentine, J.3
Gabriel, A.4
Swift, S.5
Ross, G.6
Griffin, C.7
Thacker, J.8
Ashworth, A.9
-
26
-
-
0038650956
-
An introduction to pancreatic adenocarcinoma genetics, pathology and therapy
-
Kern SE, Hruban RH, Hidalgo M, Yeo CJ: An introduction to pancreatic adenocarcinoma genetics, pathology and therapy. Cancer Biol Ther 2002, 1:607-613
-
(2002)
Cancer Biol Ther
, vol.1
, pp. 607-613
-
-
Kern, S.E.1
Hruban, R.H.2
Hidalgo, M.3
Yeo, C.J.4
-
27
-
-
0017116304
-
Familial cancer on a Scottish island
-
Hill RD: Familial cancer on a Scottish island. Br Med J 1976, 2:401-402
-
(1976)
Br Med J
, vol.2
, pp. 401-402
-
-
Hill, R.D.1
-
28
-
-
0031985201
-
DNA cross-linker-induced G2/M arrest in group C Fanconi anemia lymphoblasts reflects normal checkpoint function
-
Heinrich MC, Hoatlin ME, Zigler AJ, Silvey KV, Bakke AC, Keeble WW, Zhi Y, Reifsteck CA, Grompe M, Brown MG, Magenis RE, Olson SB, Bagby GC: DNA cross-linker-induced G2/M arrest in group C Fanconi anemia lymphoblasts reflects normal checkpoint function. Blood 1998, 91:275-287
-
(1998)
Blood
, vol.91
, pp. 275-287
-
-
Heinrich, M.C.1
Hoatlin, M.E.2
Zigler, A.J.3
Silvey, K.V.4
Bakke, A.C.5
Keeble, W.W.6
Zhi, Y.7
Reifsteck, C.A.8
Grompe, M.9
Brown, M.G.10
Magenis, R.E.11
Olson, S.B.12
Bagby, G.C.13
-
29
-
-
0024566852
-
Repair analysis of mitomycin C-induced DNA crosslinking in ribosomal RNA genes in lymphoblastoid cells from Fanconi's anemia patients
-
Matsumoto A, Vos JM, Hanawalt PC: Repair analysis of mitomycin C-induced DNA crosslinking in ribosomal RNA genes in lymphoblastoid cells from Fanconi's anemia patients. Mutat Res 1989, 217:185-192
-
(1989)
Mutat Res
, vol.217
, pp. 185-192
-
-
Matsumoto, A.1
Vos, J.M.2
Hanawalt, P.C.3
-
30
-
-
0035691754
-
The 4N cell cycle delay in Fanconi anemia reflects growth arrest in late S phase
-
Akkari YM, Bateman RL, Reifsteck CA, D'Andrea AD, Olson SB, Grompe M: The 4N cell cycle delay in Fanconi anemia reflects growth arrest in late S phase. Mol Genet Metab 2001, 74:403-412
-
(2001)
Mol Genet Metab
, vol.74
, pp. 403-412
-
-
Akkari, Y.M.1
Bateman, R.L.2
Reifsteck, C.A.3
D'Andrea, A.D.4
Olson, S.B.5
Grompe, M.6
-
31
-
-
16944367477
-
Abrogation of the Rb/p16 tumorsuppressive pathway in virtually all pancreatic carcinomas
-
Schutte M, Hruban RH, Geradts J, Maynard R, Hilgers W, Rabindran SK, Moskaluk CA, Hahn SA, Schwarte-Waldhoff I, Schmiegel W, Baylin SB, Kern SE, Herman JG: Abrogation of the Rb/p16 tumorsuppressive pathway in virtually all pancreatic carcinomas. Cancer Res 1997, 57:3126-3130
-
(1997)
Cancer Res
, vol.57
, pp. 3126-3130
-
-
Schutte, M.1
Hruban, R.H.2
Geradts, J.3
Maynard, R.4
Hilgers, W.5
Rabindran, S.K.6
Moskaluk, C.A.7
Hahn, S.A.8
Schwarte-Waldhoff, I.9
Schmiegel, W.10
Baylin, S.B.11
Kern, S.E.12
Herman, J.G.13
-
32
-
-
0028308492
-
p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions
-
Redston MS, Caldas C, Seymour AB, Hruban RH, da Costa L, Yeo CJ, Kern SE: p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions. Cancer Res 1994, 54:3025-3033
-
(1994)
Cancer Res
, vol.54
, pp. 3025-3033
-
-
Redston, M.S.1
Caldas, C.2
Seymour, A.B.3
Hruban, R.H.4
Da Costa, L.5
Yeo, C.J.6
Kern, S.E.7
-
33
-
-
0038075462
-
Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors
-
Taniguchi T, Tischkowitz M, Ameziane N, Hodgson SV, Mathew CG, Joenje H, Mok SC, D'Andrea AD: Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nat Med 2003, 9:568-574
-
(2003)
Nat Med
, vol.9
, pp. 568-574
-
-
Taniguchi, T.1
Tischkowitz, M.2
Ameziane, N.3
Hodgson, S.V.4
Mathew, C.G.5
Joenje, H.6
Mok, S.C.7
D'Andrea, A.D.8
|