-
1
-
-
64849104137
-
L-Carnitine in the lipid and protein protection against ethanol-induced oxidative stress
-
Augustyniak A., Skrzydlewska E. l-Carnitine in the lipid and protein protection against ethanol-induced oxidative stress. Alcohol 2009, 43:217-223.
-
(2009)
Alcohol
, vol.43
, pp. 217-223
-
-
Augustyniak, A.1
Skrzydlewska, E.2
-
2
-
-
0035026194
-
Chronic ethanol consumption alters the glutathione/glutathione peroxidase-1 system and protein oxidation status in rat liver
-
Bailey S.M., Patel V.B., Young T.A., Asayama K., Cunningham C.C. Chronic ethanol consumption alters the glutathione/glutathione peroxidase-1 system and protein oxidation status in rat liver. Alcoholism: Clinical and Experimental Research 2001, 25:726-733.
-
(2001)
Alcoholism: Clinical and Experimental Research
, vol.25
, pp. 726-733
-
-
Bailey, S.M.1
Patel, V.B.2
Young, T.A.3
Asayama, K.4
Cunningham, C.C.5
-
3
-
-
33751082953
-
S-Adenosylmethionine prevents chronic alcohol-induced mitochondrial dysfunction in the rat liver
-
Bailey S.M., Robinson G., Pinner A., Chamlee L., Ulasova E., Pompilius M., Page G.P., Chhieng D., Jhala N., Landar A., Kharbanda K.K., Ballinger S., Darley-Usmar V. S-Adenosylmethionine prevents chronic alcohol-induced mitochondrial dysfunction in the rat liver. American Journal of Physiology - Gastrointestinal and Liver Physiology 2006, 291:G857-G867.
-
(2006)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.291
-
-
Bailey, S.M.1
Robinson, G.2
Pinner, A.3
Chamlee, L.4
Ulasova, E.5
Pompilius, M.6
Page, G.P.7
Chhieng, D.8
Jhala, N.9
Landar, A.10
Kharbanda, K.K.11
Ballinger, S.12
Darley-Usmar, V.13
-
4
-
-
33747605553
-
Cytochrome P450 2E1-dependent oxidant stress and upregulation of anti-oxidant defense in liver cells
-
Cederbaum A.I. Cytochrome P450 2E1-dependent oxidant stress and upregulation of anti-oxidant defense in liver cells. Journal of Gastroenterology and Hepatology 2006, 21:S22-S25.
-
(2006)
Journal of Gastroenterology and Hepatology
, vol.21
-
-
Cederbaum, A.I.1
-
6
-
-
0031812227
-
Cytotoxicity and apoptosis produced by arachidonic acid in HepG2 cells overexpressing human cytochrome P-4502E1
-
Chen Q., Galleano M., Cederbaum A.I. Cytotoxicity and apoptosis produced by arachidonic acid in HepG2 cells overexpressing human cytochrome P-4502E1. Alcoholism: Clinical and Experimental Research 1998, 22:782-784.
-
(1998)
Alcoholism: Clinical and Experimental Research
, vol.22
, pp. 782-784
-
-
Chen, Q.1
Galleano, M.2
Cederbaum, A.I.3
-
7
-
-
77249150883
-
TGF-beta enhances alcohol dependent hepatocyte damage via down-regulation of alcohol dehydrogenase I
-
Ciuclan L., Ehnert S., Ilkavets I., Wend H.L., Gaitantzi H., Tsukamoto H., Ueberham E., Meindl-Beinker N.M., Singer M.V., Breitkopf K., Dooley S. TGF-beta enhances alcohol dependent hepatocyte damage via down-regulation of alcohol dehydrogenase I. Journal of Hepatology 2010, 52:407-416.
-
(2010)
Journal of Hepatology
, vol.52
, pp. 407-416
-
-
Ciuclan, L.1
Ehnert, S.2
Ilkavets, I.3
Wend, H.L.4
Gaitantzi, H.5
Tsukamoto, H.6
Ueberham, E.7
Meindl-Beinker, N.M.8
Singer, M.V.9
Breitkopf, K.10
Dooley, S.11
-
8
-
-
0029147693
-
Establishment of a recombinant hepatic cell line stably expressing alcohol dehydrogenase
-
Clemens D.L., Halgard C.M., Miles R.R., Sorrell M.F., Tuma D.J. Establishment of a recombinant hepatic cell line stably expressing alcohol dehydrogenase. Archives of Biochemistry and Biophysics 1995, 321:311-318.
-
(1995)
Archives of Biochemistry and Biophysics
, vol.321
, pp. 311-318
-
-
Clemens, D.L.1
Halgard, C.M.2
Miles, R.R.3
Sorrell, M.F.4
Tuma, D.J.5
-
9
-
-
66149103602
-
Exogenous thioredoxin prevents ethanol-induced oxidative damage and apoptosis in mouse liver
-
Cohen J.I., Roychowdhury S., DiBello P.M., Jacobsen D.W., Nagy L.E. Exogenous thioredoxin prevents ethanol-induced oxidative damage and apoptosis in mouse liver. Hepatology 2009, 49:1709-1717.
-
(2009)
Hepatology
, vol.49
, pp. 1709-1717
-
-
Cohen, J.I.1
Roychowdhury, S.2
DiBello, P.M.3
Jacobsen, D.W.4
Nagy, L.E.5
-
10
-
-
77955474503
-
Complement and alcoholic liver disease: role of C1q in the pathogenesis of ethanol-induced liver injury in mice
-
(674.e1)
-
Cohen J.I., Roychowdhury S., McMullen M.R., Stavitsky A.B., Nagy L.E. Complement and alcoholic liver disease: role of C1q in the pathogenesis of ethanol-induced liver injury in mice. Gastroenterology 2010, 139:664-674. (674.e1).
-
(2010)
Gastroenterology
, vol.139
, pp. 664-674
-
-
Cohen, J.I.1
Roychowdhury, S.2
McMullen, M.R.3
Stavitsky, A.B.4
Nagy, L.E.5
-
11
-
-
74549208029
-
Chronic ethanol consumption results in atypical liver injury in copper/zinc superoxide dismutase deficient mice
-
Curry-McCoy T.V., Osna N.A., Nanji A.A., Donohue T.M. Chronic ethanol consumption results in atypical liver injury in copper/zinc superoxide dismutase deficient mice. Alcoholism: Clinical and Experimental Research 2010, 34:251-261.
-
(2010)
Alcoholism: Clinical and Experimental Research
, vol.34
, pp. 251-261
-
-
Curry-McCoy, T.V.1
Osna, N.A.2
Nanji, A.A.3
Donohue, T.M.4
-
12
-
-
33646820349
-
Geldanamycin, an inhibitor of Hsp90, potentiates cytochrome P4502E1-mediated toxicity in HepG2 cells
-
Dey A., Cederbaum A.I. Geldanamycin, an inhibitor of Hsp90, potentiates cytochrome P4502E1-mediated toxicity in HepG2 cells. Journal of Pharmacology and Experimental Therapeutics 2006, 317:1391-1399.
-
(2006)
Journal of Pharmacology and Experimental Therapeutics
, vol.317
, pp. 1391-1399
-
-
Dey, A.1
Cederbaum, A.I.2
-
13
-
-
34250375240
-
Induction of cytochrome P450 2E1 [corrected] promotes liver injury in ob/ob mice
-
Dey A., Cederbaum A.I. Induction of cytochrome P450 2E1 [corrected] promotes liver injury in ob/ob mice. Hepatology 2007, 45:1355-1365.
-
(2007)
Hepatology
, vol.45
, pp. 1355-1365
-
-
Dey, A.1
Cederbaum, A.I.2
-
15
-
-
27544457323
-
Recombinant HepG2 cells that express alcohol dehydrogenase and cytochrome P450 2E1 as a model of ethanol-elicited cytotoxicity
-
Donohue T.M., Osna N.A., Clemens D.L. Recombinant HepG2 cells that express alcohol dehydrogenase and cytochrome P450 2E1 as a model of ethanol-elicited cytotoxicity. International Journal of Biochemistry Cell Biology 2006, 38:92-101.
-
(2006)
International Journal of Biochemistry Cell Biology
, vol.38
, pp. 92-101
-
-
Donohue, T.M.1
Osna, N.A.2
Clemens, D.L.3
-
16
-
-
0024546914
-
Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P-450 (P-450IIE1)
-
Ekström G., Ingelman-Sundberg M. Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P-450 (P-450IIE1). Biochemical Pharmacology 1989, 38:1313-1319.
-
(1989)
Biochemical Pharmacology
, vol.38
, pp. 1313-1319
-
-
Ekström, G.1
Ingelman-Sundberg, M.2
-
17
-
-
77954595108
-
Glucolipotoxicity alters lipid partitioning and causes mitochondrial dysfunction, cholesterol, and ceramide deposition and reactive oxygen species production in INS832/13 ss-cells
-
El-Assaad W., Joly E., Barbeau A., Sladek R., Buteau J., Maestre I., Pepin E., Zhao S., Iglesias J., Roche E., Prentki M. Glucolipotoxicity alters lipid partitioning and causes mitochondrial dysfunction, cholesterol, and ceramide deposition and reactive oxygen species production in INS832/13 ss-cells. Endocrinology 2010, 151:3061-3073.
-
(2010)
Endocrinology
, vol.151
, pp. 3061-3073
-
-
El-Assaad, W.1
Joly, E.2
Barbeau, A.3
Sladek, R.4
Buteau, J.5
Maestre, I.6
Pepin, E.7
Zhao, S.8
Iglesias, J.9
Roche, E.10
Prentki, M.11
-
18
-
-
61349140665
-
Effects of N-acetylcysteine on alcohol abstinence and alcohol-induced adverse effects in rats
-
Ferreira Seiva F.R., Amauchi J.F., Ribeiro Rocha K.K., Souza G.A., Ebaid G.X., Burneiko R.M., Novelli E.L. Effects of N-acetylcysteine on alcohol abstinence and alcohol-induced adverse effects in rats. Alcohol 2009, 43:127-135.
-
(2009)
Alcohol
, vol.43
, pp. 127-135
-
-
Ferreira Seiva, F.R.1
Amauchi, J.F.2
Ribeiro Rocha, K.K.3
Souza, G.A.4
Ebaid, G.X.5
Burneiko, R.M.6
Novelli, E.L.7
-
19
-
-
33644790212
-
Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1
-
Gong P., Cederbaum A.I. Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1. Hepatology 2006, 43:144-153.
-
(2006)
Hepatology
, vol.43
, pp. 144-153
-
-
Gong, P.1
Cederbaum, A.I.2
-
20
-
-
0042531793
-
Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway
-
Gong P., Cederbaum A.I., Nieto N. Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway. Journal of Biological Chemistry 2003, 278:29693-29700.
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 29693-29700
-
-
Gong, P.1
Cederbaum, A.I.2
Nieto, N.3
-
21
-
-
33845953191
-
The 2006 Bernard B. Brodie Award Lecture. Cyp2e1
-
Gonzalez F.J. The 2006 Bernard B. Brodie Award Lecture. Cyp2e1. Drug Metabolism and Disposition 2007, 35:1-8.
-
(2007)
Drug Metabolism and Disposition
, vol.35
, pp. 1-8
-
-
Gonzalez, F.J.1
-
22
-
-
0033872080
-
Inhibition of ethanol-induced liver disease in the intragastric feeding rat model by chlormethiazole
-
Gouillon Z., Lucas D., Li J., Hagbjork A.L., French B.A., Fu P. Inhibition of ethanol-induced liver disease in the intragastric feeding rat model by chlormethiazole. Proceeding of the Society for Experimental Biology Medicine 2000, 224:302-308.
-
(2000)
Proceeding of the Society for Experimental Biology Medicine
, vol.224
, pp. 302-308
-
-
Gouillon, Z.1
Lucas, D.2
Li, J.3
Hagbjork, A.L.4
French, B.A.5
Fu, P.6
-
23
-
-
33748892142
-
Review article: alcoholic liver disease-pathophysiological aspects and risk factors
-
Gramenzi A., Caputo F., Biselli M., Kuria F., Loggi E., Andreone P., Bernardi M. Review article: alcoholic liver disease-pathophysiological aspects and risk factors. Alimentary Pharmacology and Therapeutics 2006, 24:1151-1161.
-
(2006)
Alimentary Pharmacology and Therapeutics
, vol.24
, pp. 1151-1161
-
-
Gramenzi, A.1
Caputo, F.2
Biselli, M.3
Kuria, F.4
Loggi, E.5
Andreone, P.6
Bernardi, M.7
-
24
-
-
77749261106
-
Ethanol-induced oxidative stress and mitochondrial dysfunction in rat placenta: relevance to pregnancy loss
-
Gundogan F., Elwood G., Mark P., Feijoo A., Longato L., Tong M., de la Monte S.M. Ethanol-induced oxidative stress and mitochondrial dysfunction in rat placenta: relevance to pregnancy loss. Alcoholism: Clinical and Experimental Research 2010, 34:415-423.
-
(2010)
Alcoholism: Clinical and Experimental Research
, vol.34
, pp. 415-423
-
-
Gundogan, F.1
Elwood, G.2
Mark, P.3
Feijoo, A.4
Longato, L.5
Tong, M.6
de la Monte, S.M.7
-
25
-
-
77649282341
-
Alcohol dehydrogenase accentuates ethanol-induced myocardial dysfunction and mitochondrial damage in mice: role of mitochondrial death pathway
-
Guo R., Ren J. Alcohol dehydrogenase accentuates ethanol-induced myocardial dysfunction and mitochondrial damage in mice: role of mitochondrial death pathway. Public Library of Science One 2010, 5:e8757.
-
(2010)
Public Library of Science One
, vol.5
-
-
Guo, R.1
Ren, J.2
-
26
-
-
33645935393
-
The effect of ethanol, ethanol metabolizing enzyme inhibitors, and Vitamin E on regulating glutathione, glutathione S-transferase, and S-adenosylmethionine in mouse primary hepatocyte
-
Gyamfi M.A., Wan Y.J. The effect of ethanol, ethanol metabolizing enzyme inhibitors, and Vitamin E on regulating glutathione, glutathione S-transferase, and S-adenosylmethionine in mouse primary hepatocyte. Hepatology Research 2006, 35:53-61.
-
(2006)
Hepatology Research
, vol.35
, pp. 53-61
-
-
Gyamfi, M.A.1
Wan, Y.J.2
-
27
-
-
0032610934
-
Glutathione and the regulation of cell death
-
Hall A.G. Glutathione and the regulation of cell death. Advances in Experimental Medical Biology 1999, 457:199-203.
-
(1999)
Advances in Experimental Medical Biology
, vol.457
, pp. 199-203
-
-
Hall, A.G.1
-
28
-
-
56049117834
-
Mechanism of alcohol-induced oxidative stress and neuronal injury
-
Haorah J., Ramirez S.H., Floreani N., Gorantla S., Morsey B., Persidsky Y. Mechanism of alcohol-induced oxidative stress and neuronal injury. Free Radical Biology and Medicine 2008, 45:1542-1550.
-
(2008)
Free Radical Biology and Medicine
, vol.45
, pp. 1542-1550
-
-
Haorah, J.1
Ramirez, S.H.2
Floreani, N.3
Gorantla, S.4
Morsey, B.5
Persidsky, Y.6
-
29
-
-
0028842190
-
The hepatocellular metabolism of 4-hydroxynonenal by alcohol dehydrogenase, aldehyde dehydrogenase, and glutathione S-transferase
-
Hartley D.P., Ruth J.A., Petersen D.R. The hepatocellular metabolism of 4-hydroxynonenal by alcohol dehydrogenase, aldehyde dehydrogenase, and glutathione S-transferase. Archives of Biochemistry and Biophysics 1995, 316:197-205.
-
(1995)
Archives of Biochemistry and Biophysics
, vol.316
, pp. 197-205
-
-
Hartley, D.P.1
Ruth, J.A.2
Petersen, D.R.3
-
30
-
-
1642524322
-
Toxicity of ethanol and acetaldehyde in hepatocytes treated with ursodeoxycholic or tauroursodeoxycholic acid
-
Henzel K., Thorborg C., Hofmann M., Zimmer G., Leuschner U. Toxicity of ethanol and acetaldehyde in hepatocytes treated with ursodeoxycholic or tauroursodeoxycholic acid. Biochimica et Biophysics Acta 2004, 1644:37-45.
-
(2004)
Biochimica et Biophysics Acta
, vol.1644
, pp. 37-45
-
-
Henzel, K.1
Thorborg, C.2
Hofmann, M.3
Zimmer, G.4
Leuschner, U.5
-
31
-
-
34548382456
-
Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1 expression
-
Hodges N.J., Green R.M., Chipman J.K., Graham M. Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1 expression. Mutagenesis 2007, 22:189-194.
-
(2007)
Mutagenesis
, vol.22
, pp. 189-194
-
-
Hodges, N.J.1
Green, R.M.2
Chipman, J.K.3
Graham, M.4
-
32
-
-
37249091222
-
Synergistic toxicity induced by prolonged glutathione depletion and inhibition of nuclear factor-kappaB signaling in liver cells
-
Jimenez-Lopez J.M., Wu D., Cederbaum A.I. Synergistic toxicity induced by prolonged glutathione depletion and inhibition of nuclear factor-kappaB signaling in liver cells. Toxicology In Vitro 2008, 22:106-115.
-
(2008)
Toxicology In Vitro
, vol.22
, pp. 106-115
-
-
Jimenez-Lopez, J.M.1
Wu, D.2
Cederbaum, A.I.3
-
33
-
-
0021925444
-
An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide
-
Jones K.H., Senft J.A. An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide. Journal of Histochemistry and Cytochemistry 1985, 33:77-79.
-
(1985)
Journal of Histochemistry and Cytochemistry
, vol.33
, pp. 77-79
-
-
Jones, K.H.1
Senft, J.A.2
-
34
-
-
37049019073
-
Role of CYP2E1 in diethylnitrosamine-induced hepatocarcinogenesis in vivo
-
Kang J.S., Wanibuchi H., Morimura K., Gonzalez F.J., Fukushima S. Role of CYP2E1 in diethylnitrosamine-induced hepatocarcinogenesis in vivo. Cancer Research 2007, 67:11141-11146.
-
(2007)
Cancer Research
, vol.67
, pp. 11141-11146
-
-
Kang, J.S.1
Wanibuchi, H.2
Morimura, K.3
Gonzalez, F.J.4
Fukushima, S.5
-
35
-
-
77956881587
-
Pancreatic injury in hepatic alcohol dehydrogenase-deficient deer mice after subchronic exposure to ethanol
-
Kaphalia B.S., Bhopale K.K., Kondraganti S., Wu H., Boor P.J., Ansari G.A. Pancreatic injury in hepatic alcohol dehydrogenase-deficient deer mice after subchronic exposure to ethanol. Toxicology and Applied Pharmacology 2010, 246:154-162.
-
(2010)
Toxicology and Applied Pharmacology
, vol.246
, pp. 154-162
-
-
Kaphalia, B.S.1
Bhopale, K.K.2
Kondraganti, S.3
Wu, H.4
Boor, P.J.5
Ansari, G.A.6
-
36
-
-
59049087962
-
Ethanol-induced expression of glutamate-cysteine ligase catalytic subunit gene is mediated by NF-kappaB
-
Kimura T., Kawasaki Y., Okumura F., Sone T., Natsuki R., Isobe M. Ethanol-induced expression of glutamate-cysteine ligase catalytic subunit gene is mediated by NF-kappaB. Toxicology Letters 2009, 185:110-115.
-
(2009)
Toxicology Letters
, vol.185
, pp. 110-115
-
-
Kimura, T.1
Kawasaki, Y.2
Okumura, F.3
Sone, T.4
Natsuki, R.5
Isobe, M.6
-
37
-
-
0022494453
-
Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a
-
Koop D.R. Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a. Molecular Pharmacology 1986, 29:399-404.
-
(1986)
Molecular Pharmacology
, vol.29
, pp. 399-404
-
-
Koop, D.R.1
-
38
-
-
25844469063
-
Use of CYP2E1-transfected human liver cell lines in elucidating the actions of ethanol
-
Lakshman R., Cederbaum A.I., Hoek J.B., Konishi M., Koop D., Donohue T.M. Use of CYP2E1-transfected human liver cell lines in elucidating the actions of ethanol. Alcoholism: Clinical and Experimental Research 2006, 29:1726-1734.
-
(2006)
Alcoholism: Clinical and Experimental Research
, vol.29
, pp. 1726-1734
-
-
Lakshman, R.1
Cederbaum, A.I.2
Hoek, J.B.3
Konishi, M.4
Koop, D.5
Donohue, T.M.6
-
39
-
-
77951543299
-
Chronic alcohol consumption is associated with an increased cytotoxic profile of circulating lymphocytes that may be related with the development of liver injury
-
Laso F.J., Almeida J., Torres E., Vaquero J.M., Marcos M., Orfao A. Chronic alcohol consumption is associated with an increased cytotoxic profile of circulating lymphocytes that may be related with the development of liver injury. Alcoholism: Clinical and Experimental Research 2010, 34:876-885.
-
(2010)
Alcoholism: Clinical and Experimental Research
, vol.34
, pp. 876-885
-
-
Laso, F.J.1
Almeida, J.2
Torres, E.3
Vaquero, J.M.4
Marcos, M.5
Orfao, A.6
-
40
-
-
74549215141
-
Prohibitin is expressed in pancreatic beta-cells and protects against oxidative and proapoptotic effects of ethanol
-
Lee J.H., Nguyen K.H., Mishra S., Nyomba B.L. Prohibitin is expressed in pancreatic beta-cells and protects against oxidative and proapoptotic effects of ethanol. The FEBS Journal 2010, 277:488-500.
-
(2010)
The FEBS Journal
, vol.277
, pp. 488-500
-
-
Lee, J.H.1
Nguyen, K.H.2
Mishra, S.3
Nyomba, B.L.4
-
41
-
-
15844419997
-
Role of CYP2E1 in the hepatotoxicity of acetaminophen
-
Lee S.S., Buters J.T., Pineau T., Fernandez-Salguero P., Gonzalez F.J. Role of CYP2E1 in the hepatotoxicity of acetaminophen. Journal of Biological Chemistry 1996, 271:12063-12067.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 12063-12067
-
-
Lee, S.S.1
Buters, J.T.2
Pineau, T.3
Fernandez-Salguero, P.4
Gonzalez, F.J.5
-
42
-
-
0030935567
-
Cytochrome P-4502E1: its physiological and pathological role
-
Lieber C.S. Cytochrome P-4502E1: its physiological and pathological role. Physiological Reviews 1997, 77:517-544.
-
(1997)
Physiological Reviews
, vol.77
, pp. 517-544
-
-
Lieber, C.S.1
-
43
-
-
7544222395
-
The discovery of the microsomal ethanol oxidizing system and its physiologic and pathologic role
-
Lieber C.S. The discovery of the microsomal ethanol oxidizing system and its physiologic and pathologic role. Drug Metabolism Reviews 2004, 36:511-529.
-
(2004)
Drug Metabolism Reviews
, vol.36
, pp. 511-529
-
-
Lieber, C.S.1
-
44
-
-
71849104860
-
Protein measurement with the Folin-phenol reagent
-
Lowry O.H., Rosenbrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin-phenol reagent. Journal of Biological Chemistry 1951, 193:265-275.
-
(1951)
Journal of Biological Chemistry
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosenbrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
45
-
-
75149156623
-
CFTR mediates apoptotic volume decrease and cell death by controlling glutathione efflux and ROS production in cultured mice proximal tubules
-
l'Hoste S., Chargui A., Belfodil R., Corcelle E., Duranton C., Rubera I., Poujeol C., Mograbi B., Tauc M., Poujeol P. CFTR mediates apoptotic volume decrease and cell death by controlling glutathione efflux and ROS production in cultured mice proximal tubules. American Journal of Physiology - Renal Physiology 2010, 298:F435-F453.
-
(2010)
American Journal of Physiology - Renal Physiology
, vol.298
-
-
l'Hoste, S.1
Chargui, A.2
Belfodil, R.3
Corcelle, E.4
Duranton, C.5
Rubera, I.6
Poujeol, C.7
Mograbi, B.8
Tauc, M.9
Poujeol, P.10
-
46
-
-
0034685775
-
CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of gamma-glutamylcysteine synthetase
-
Marí M., Cederbaum A.I. CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of gamma-glutamylcysteine synthetase. Journal of Biological Chemistry 2000, 275:15563-15571.
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 15563-15571
-
-
Marí, M.1
Cederbaum, A.I.2
-
47
-
-
33751003258
-
Inactivation of oxidized and S-nitrosylated mitochondrial proteins in alcoholic fatty liver of rats
-
Moon K.H., Hood B.L., Kim B.J., Hardwick J.P., Conrads T.P., Veenstra T.D., Song B.J. Inactivation of oxidized and S-nitrosylated mitochondrial proteins in alcoholic fatty liver of rats. Hepatology 2006, 44:1218-1230.
-
(2006)
Hepatology
, vol.44
, pp. 1218-1230
-
-
Moon, K.H.1
Hood, B.L.2
Kim, B.J.3
Hardwick, J.P.4
Conrads, T.P.5
Veenstra, T.D.6
Song, B.J.7
-
48
-
-
0027745582
-
Role of cytochrome P4502E1 in alcoholic liver disease pathogenesis
-
Morimoto M., Hagbjork A.L., Nanji A.A., Ingelman-Sundberg M., Lindros K.O., Fu P.C., Albano E., French S.W. Role of cytochrome P4502E1 in alcoholic liver disease pathogenesis. Alcohol 1993, 10:459-464.
-
(1993)
Alcohol
, vol.10
, pp. 459-464
-
-
Morimoto, M.1
Hagbjork, A.L.2
Nanji, A.A.3
Ingelman-Sundberg, M.4
Lindros, K.O.5
Fu, P.C.6
Albano, E.7
French, S.W.8
-
49
-
-
0029016297
-
Modulation of experimental alcohol-induced liver disease by cytochrome P450 2E1 inhibitors
-
Morimoto M., Hagbjork A.L., Wan Y.J., Fu P.C., Clot P., Albano E. Modulation of experimental alcohol-induced liver disease by cytochrome P450 2E1 inhibitors. Hepatology 1995, 21:1610-1617.
-
(1995)
Hepatology
, vol.21
, pp. 1610-1617
-
-
Morimoto, M.1
Hagbjork, A.L.2
Wan, Y.J.3
Fu, P.C.4
Clot, P.5
Albano, E.6
-
51
-
-
29344468246
-
Ethanol rapidly causes activation of JNK associated with ER stress under inhibition of ADH
-
Nishitani Y., Matsumoto H. Ethanol rapidly causes activation of JNK associated with ER stress under inhibition of ADH. FEBS Letters 2006, 580:9-14.
-
(2006)
FEBS Letters
, vol.580
, pp. 9-14
-
-
Nishitani, Y.1
Matsumoto, H.2
-
52
-
-
77952671496
-
Hypochlorite modification of sphingomyelin generates chlorinated lipid species that induce apoptosis and proteome alterations in dopaminergic PC12 neurons in vitro
-
Nusshold C., Kollroser M., Köfeler H., Rechberger G., Reicher H., Ullen A., Bernhart E., Waltl S., Kratzer I., Hermetter A., Hackl H., Trajanoski Z., Hrzenjak A., Malle E., Sattler W. Hypochlorite modification of sphingomyelin generates chlorinated lipid species that induce apoptosis and proteome alterations in dopaminergic PC12 neurons in vitro. Free Radical Biology and Medicine 2010, 48:1588-1600.
-
(2010)
Free Radical Biology and Medicine
, vol.48
, pp. 1588-1600
-
-
Nusshold, C.1
Kollroser, M.2
Köfeler, H.3
Rechberger, G.4
Reicher, H.5
Ullen, A.6
Bernhart, E.7
Waltl, S.8
Kratzer, I.9
Hermetter, A.10
Hackl, H.11
Trajanoski, Z.12
Hrzenjak, A.13
Malle, E.14
Sattler, W.15
-
53
-
-
30944453568
-
Ethanol metabolism alters interferon gamma signaling in recombinant HepG2 cells
-
Osna N.A., Clemens D.L., Donohue T.M. Ethanol metabolism alters interferon gamma signaling in recombinant HepG2 cells. Hepatology 2005, 42:1109-1117.
-
(2005)
Hepatology
, vol.42
, pp. 1109-1117
-
-
Osna, N.A.1
Clemens, D.L.2
Donohue, T.M.3
-
54
-
-
11144342818
-
Hepatitis C virus core protein, cytochrome P450 2E1, and alcohol produce combined mitochondrial injury and cytotoxicity in hepatoma cells
-
Otani K., Korenaga M., Beard M.R., Li K., Qian T., Showalter L.A., Singh A.K., Wang T., Weinman S.A. Hepatitis C virus core protein, cytochrome P450 2E1, and alcohol produce combined mitochondrial injury and cytotoxicity in hepatoma cells. Gastroenterology 2005, 128:96-107.
-
(2005)
Gastroenterology
, vol.128
, pp. 96-107
-
-
Otani, K.1
Korenaga, M.2
Beard, M.R.3
Li, K.4
Qian, T.5
Showalter, L.A.6
Singh, A.K.7
Wang, T.8
Weinman, S.A.9
-
55
-
-
36048941086
-
Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis
-
Palmeira C.M., Rolo A.P., Berthiaume J., Bjork J.A., Wallace K.B. Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis. Toxicology and Applied Pharmacology 2007, 225:214-220.
-
(2007)
Toxicology and Applied Pharmacology
, vol.225
, pp. 214-220
-
-
Palmeira, C.M.1
Rolo, A.P.2
Berthiaume, J.3
Bjork, J.A.4
Wallace, K.B.5
-
56
-
-
77957844254
-
Reactive oxygen species, oxidative stress, and cell death correlate with level of CoQ10 deficiency
-
Quinzii C.M., Lopez L.C., Gilkerson R.W., Dorado B., Coku J., Naini A.B., Lagier-Tourenne C., Schuelke M., Salviati L., Carrozzo R., Santorelli F., Rahman S., Tazir M., Koenig M., Dimauro S., Hirano M. Reactive oxygen species, oxidative stress, and cell death correlate with level of CoQ10 deficiency. The FASEB Journal 2010, 24:3733-3743.
-
(2010)
The FASEB Journal
, vol.24
, pp. 3733-3743
-
-
Quinzii, C.M.1
Lopez, L.C.2
Gilkerson, R.W.3
Dorado, B.4
Coku, J.5
Naini, A.B.6
Lagier-Tourenne, C.7
Schuelke, M.8
Salviati, L.9
Carrozzo, R.10
Santorelli, F.11
Rahman, S.12
Tazir, M.13
Koenig, M.14
Dimauro, S.15
Hirano, M.16
-
57
-
-
33749057888
-
4-Hydroxynonenal induces mitochondrial oxidative stress, apoptosis and expression of glutathione S-transferase A4-4 and cytochrome P450 2E1 in PC12 cells
-
Raza H., John A. 4-Hydroxynonenal induces mitochondrial oxidative stress, apoptosis and expression of glutathione S-transferase A4-4 and cytochrome P450 2E1 in PC12 cells. Toxicology and Applied Pharmacology 2006, 216:309-318.
-
(2006)
Toxicology and Applied Pharmacology
, vol.216
, pp. 309-318
-
-
Raza, H.1
John, A.2
-
58
-
-
77954656608
-
Lipid-induced up-regulation of human acyl-CoA synthetase 5 promotes hepatocellular apoptosis
-
Reinartz A., Ehling J., Leue A., Liedtke C., Schneider U., Kopitz J., Weiss T., Hellerbrand C., Weiskirchen R., Knüchel R., Gassler N. Lipid-induced up-regulation of human acyl-CoA synthetase 5 promotes hepatocellular apoptosis. Biochimica et Biophysica Acta 2010, 1801:1025-1035.
-
(2010)
Biochimica et Biophysica Acta
, vol.1801
, pp. 1025-1035
-
-
Reinartz, A.1
Ehling, J.2
Leue, A.3
Liedtke, C.4
Schneider, U.5
Kopitz, J.6
Weiss, T.7
Hellerbrand, C.8
Weiskirchen, R.9
Knüchel, R.10
Gassler, N.11
-
59
-
-
28844465328
-
Alcohol increases tumor necrosis factor alpha and decreases nuclear factor-kappaB to activate hepatic apoptosis in genetically obese mice
-
Robin M.A., Demeilliers C., Sutton A., Paradis V., Maisonneuve C., Dubois S., Poirel O., Lettéron P., Pessayre D., Fromenty B. Alcohol increases tumor necrosis factor alpha and decreases nuclear factor-kappaB to activate hepatic apoptosis in genetically obese mice. Hepatology 2005, 42:1280-1290.
-
(2005)
Hepatology
, vol.42
, pp. 1280-1290
-
-
Robin, M.A.1
Demeilliers, C.2
Sutton, A.3
Paradis, V.4
Maisonneuve, C.5
Dubois, S.6
Poirel, O.7
Lettéron, P.8
Pessayre, D.9
Fromenty, B.10
-
60
-
-
77249093012
-
The role of ethanol metabolism in development of alcoholic steatohepatitis in the rat
-
Ronis M.J., Korourian S., Blackburn M.L., Badeaux J., Badger T.M. The role of ethanol metabolism in development of alcoholic steatohepatitis in the rat. Alcohol 2010, 44:157-169.
-
(2010)
Alcohol
, vol.44
, pp. 157-169
-
-
Ronis, M.J.1
Korourian, S.2
Blackburn, M.L.3
Badeaux, J.4
Badger, T.M.5
-
61
-
-
70350619895
-
Formation of gamma-ketoaldehyde-protein adducts during ethanol-induced liver injury in mice
-
Roychowdhury S., McMullen M.R., Pritchard M.T., Li W., Salomon R.G., Nagy L.E. Formation of gamma-ketoaldehyde-protein adducts during ethanol-induced liver injury in mice. Free Radical Biology and Medicine 2009, 47:1526-1538.
-
(2009)
Free Radical Biology and Medicine
, vol.47
, pp. 1526-1538
-
-
Roychowdhury, S.1
McMullen, M.R.2
Pritchard, M.T.3
Li, W.4
Salomon, R.G.5
Nagy, L.E.6
-
62
-
-
73449143152
-
Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine
-
Saito C., Zwingmann C., Jaeschke H. Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine. Hepatology 2010, 51:246-254.
-
(2010)
Hepatology
, vol.51
, pp. 246-254
-
-
Saito, C.1
Zwingmann, C.2
Jaeschke, H.3
-
63
-
-
77954381149
-
Cholestasis induces apoptosis in mice cardiac cells: the possible role of nitric oxide and oxidative stress
-
Shafaroodi H., Ebrahimi F., Moezi L., Hashemi M., Doostar Y., Ghasemi M., Dehpour A.R. Cholestasis induces apoptosis in mice cardiac cells: the possible role of nitric oxide and oxidative stress. Liver International 2010, 30:898-905.
-
(2010)
Liver International
, vol.30
, pp. 898-905
-
-
Shafaroodi, H.1
Ebrahimi, F.2
Moezi, L.3
Hashemi, M.4
Doostar, Y.5
Ghasemi, M.6
Dehpour, A.R.7
-
64
-
-
72249097158
-
Chronic oxidative stress sensitizes hepatocytes to death from 4-hydroxynonenal by JNK/c-Jun overactivation
-
Singh R., Wang Y., Schattenberg J.M., Xiang Y., Czaja M.J. Chronic oxidative stress sensitizes hepatocytes to death from 4-hydroxynonenal by JNK/c-Jun overactivation. American Journal of Physiology - Gastrointestinal and Liver Physiology 2009, 297:G907-G917.
-
(2009)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.297
-
-
Singh, R.1
Wang, Y.2
Schattenberg, J.M.3
Xiang, Y.4
Czaja, M.J.5
-
65
-
-
0029829513
-
Ethanol-inducible cytochrome P450 (CYP2E1): biochemistry, molecular biology and clinical relevance
-
Song B.J., Cederbaum A.I., Koop D.R., Ingelman-Sundberg M., Nanji A. Ethanol-inducible cytochrome P450 (CYP2E1): biochemistry, molecular biology and clinical relevance. Alcoholism: Clinical and Experimental Research 1996, 20:138A-146A.
-
(1996)
Alcoholism: Clinical and Experimental Research
, vol.20
-
-
Song, B.J.1
Cederbaum, A.I.2
Koop, D.R.3
Ingelman-Sundberg, M.4
Nanji, A.5
-
66
-
-
79955470486
-
-
HEPG2 Hepatocyte Lipid Peroxidation Assay. Nanotechnology Characterization Laboratory-NCL Method GTA-4 Version 1.0.
-
Stern, S.T., Potter, T.M., Neun, B.W., 2006. HEPG2 Hepatocyte Lipid Peroxidation Assay. Nanotechnology Characterization Laboratory-NCL Method GTA-4 Version 1.0.
-
(2006)
-
-
Stern, S.T.1
Potter, T.M.2
Neun, B.W.3
-
67
-
-
34147117776
-
Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase
-
Suh S.W., Gum E.T., Hamby A.M., Chan P.H., Swanson R.A. Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase. Journal of Clinical Investigation 2007, 117:910-918.
-
(2007)
Journal of Clinical Investigation
, vol.117
, pp. 910-918
-
-
Suh, S.W.1
Gum, E.T.2
Hamby, A.M.3
Chan, P.H.4
Swanson, R.A.5
-
68
-
-
75749094680
-
Enhanced glutathione biosynthetic capacity promotes resistance to As3+-induced apoptosis
-
Thompson J.A., Franklin C.C. Enhanced glutathione biosynthetic capacity promotes resistance to As3+-induced apoptosis. Toxicology Letters 2010, 193:33-40.
-
(2010)
Toxicology Letters
, vol.193
, pp. 33-40
-
-
Thompson, J.A.1
Franklin, C.C.2
-
69
-
-
0014481378
-
Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues
-
Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Analytical Biochemistry 1969, 27:502-522.
-
(1969)
Analytical Biochemistry
, vol.27
, pp. 502-522
-
-
Tietze, F.1
-
70
-
-
67650034524
-
Hepatocyte growth factor protects hepatocytes against oxidative injury induced by ethanol metabolism
-
Valdes-Arzate A., Luna A., Bucio L., Licona C., Clemens D.L., Souza V., Hernandez E., Kershenobich D., Gutierrez-Ruiz M.C., Gomez-Quiroz L.E. Hepatocyte growth factor protects hepatocytes against oxidative injury induced by ethanol metabolism. Free Radical Biology and Medicine 2009, 47:424-430.
-
(2009)
Free Radical Biology and Medicine
, vol.47
, pp. 424-430
-
-
Valdes-Arzate, A.1
Luna, A.2
Bucio, L.3
Licona, C.4
Clemens, D.L.5
Souza, V.6
Hernandez, E.7
Kershenobich, D.8
Gutierrez-Ruiz, M.C.9
Gomez-Quiroz, L.E.10
-
71
-
-
77749258483
-
Betaine protects chronic alcohol and omega-3 PUFA-mediated down-regulations of PON1 gene, serum PON1 and homocysteine thiolactonase activities with restoration of liver GSH
-
Varatharajalu R., Garige M., Leckey L.C., Gong M., Lakshman M.R. Betaine protects chronic alcohol and omega-3 PUFA-mediated down-regulations of PON1 gene, serum PON1 and homocysteine thiolactonase activities with restoration of liver GSH. Alcoholism: Clinical and Experimental Research 2010, 34:424-431.
-
(2010)
Alcoholism: Clinical and Experimental Research
, vol.34
, pp. 424-431
-
-
Varatharajalu, R.1
Garige, M.2
Leckey, L.C.3
Gong, M.4
Lakshman, M.R.5
-
72
-
-
68949165996
-
Ethanol-induced cytochrome P4502E1 causes carcinogenic etheno-DNA lesions in alcoholic liver disease
-
Wang Y., Millonig G., Nair J., Patsenker E., Stickel F., Mueller S., Bartsch H., Seitz H.K. Ethanol-induced cytochrome P4502E1 causes carcinogenic etheno-DNA lesions in alcoholic liver disease. Hepatology 2009, 50:453-461.
-
(2009)
Hepatology
, vol.50
, pp. 453-461
-
-
Wang, Y.1
Millonig, G.2
Nair, J.3
Patsenker, E.4
Stickel, F.5
Mueller, S.6
Bartsch, H.7
Seitz, H.K.8
-
73
-
-
67650725415
-
Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: role of CYP2E1 and TNF-alpha and activation of JNK and P38 MAP kinase
-
Wang X., Lu Y., Xie B., Cederbaum A.I. Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: role of CYP2E1 and TNF-alpha and activation of JNK and P38 MAP kinase. Free Radical Biology and Medicine 2009, 47:518-528.
-
(2009)
Free Radical Biology and Medicine
, vol.47
, pp. 518-528
-
-
Wang, X.1
Lu, Y.2
Xie, B.3
Cederbaum, A.I.4
-
74
-
-
67649968443
-
Oxidative stress and alcoholic liver disease
-
Wu D., Cederbaum A.I. Oxidative stress and alcoholic liver disease. Seminars in Liver Disease 2009, 29:141-154.
-
(2009)
Seminars in Liver Disease
, vol.29
, pp. 141-154
-
-
Wu, D.1
Cederbaum, A.I.2
-
75
-
-
77954142707
-
Activation of ASK-1 and downstream MAP kinases in cytochrome P4502E1 potentiates tumor necrosis factor alpha liver injury
-
Wu D., Cederbaum A. Activation of ASK-1 and downstream MAP kinases in cytochrome P4502E1 potentiates tumor necrosis factor alpha liver injury. Free Radical Biology and Medicine 2010, 49:348-360.
-
(2010)
Free Radical Biology and Medicine
, vol.49
, pp. 348-360
-
-
Wu, D.1
Cederbaum, A.2
-
76
-
-
77954566401
-
Chronic alcohol exposure increases circulating bioactive oxidized phospholipids
-
Yang L., Latchoumycandane C., McMullen M.R., Pratt B.T., Zhang R., Papouchado B.G., Nagy L.E., Feldstein A.E., McIntyre T.M. Chronic alcohol exposure increases circulating bioactive oxidized phospholipids. Journal of Biological Chemistry 2010, 285:22211-22220.
-
(2010)
Journal of Biological Chemistry
, vol.285
, pp. 22211-22220
-
-
Yang, L.1
Latchoumycandane, C.2
McMullen, M.R.3
Pratt, B.T.4
Zhang, R.5
Papouchado, B.G.6
Nagy, L.E.7
Feldstein, A.E.8
McIntyre, T.M.9
-
77
-
-
67049145006
-
The protective role of HO-1 and its generated products (CO, bilirubin, and Fe) in ethanol-induced human hepatocyte damage
-
Yao P., Hao L., Nussler N., Lehmann A., Song F., Zhao J., Neuhaus P., Liu L., Nussler A. The protective role of HO-1 and its generated products (CO, bilirubin, and Fe) in ethanol-induced human hepatocyte damage. American Journal of Physiology - Gastrointestinal and Liver Physiology 2009, 296:G1318-G1323.
-
(2009)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.296
-
-
Yao, P.1
Hao, L.2
Nussler, N.3
Lehmann, A.4
Song, F.5
Zhao, J.6
Neuhaus, P.7
Liu, L.8
Nussler, A.9
|