Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1 expression

Mutagenesis

Volumn 22, Issue 3, 2007, Pages 189-194

  Hodges, Nikolas J ^a   Green, Richard M ^a   Chipman, James K ^a   Graham, Mark ^b  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 AMINOBENZOTRIAZOLE; ALCOHOL; BUTHIONINE SULFOXIMINE; CYTOCHROME P450; CYTOCHROME P450 2E1; DICHLOROFLUORESCEIN; DOXYCYCLINE; GLUTATHIONE; PARINARIC ACID; REACTIVE OXYGEN METABOLITE;

ARTICLE; CARCINOGENICITY; COMET ASSAY; CONTROLLED STUDY; DNA STRAND BREAKAGE; ENZYME ACTIVITY; FEMALE; GENE INDUCTION; GENE OVEREXPRESSION; HELA CELL; HUMAN; HUMAN CELL; INCUBATION TIME; LIPID PEROXIDATION; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; WESTERN BLOTTING;

CARCINOGENICITY TESTS; COMET ASSAY; CYTOCHROME P-450 CYP2E1; DNA BREAKS, SINGLE-STRANDED; ENZYME INDUCTION; ETHANOL; GLUTATHIONE; HELA CELLS; HUMANS; LIPID PEROXIDATION; METHIONINE SULFOXIMINE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 34548382456     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/gem001     Document Type: Article

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