Lipid-induced up-regulation of human acyl-CoA synthetase 5 promotes hepatocellular apoptosis

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1801, Issue 9, 2010, Pages 1025-1035

  Reinartz, Andrea ^a   Ehling, Josef ^a   Leue, Andrea ^a   Liedtke, Christian ^a   Schneider, Ursula ^a   Kopitz, Jürgen ^b   Weiss, Thomas ^c   Hellerbrand, Claus ^c   Weiskirchen, Ralf ^a   Knüchel, Ruth ^a   Gassler, Nikolaus ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Acyl CoA synthesis; Fatty acid metabolism; Lipoapoptosis; Steatosis; TNF ; TRAIL

Indexed keywords

CASPASE 3; CASPASE 7; DEATH RECEPTOR 4; DEATH RECEPTOR 5; FAS ANTIGEN; LONG CHAIN FATTY ACID COENZYME A LIGASE; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; ACSL5 PROTEIN, HUMAN; LIPID; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR;

ACSL5 GENE; APOPTOSIS; ARTICLE; CELL STRAIN HEPG2; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; FATTY ACID METABOLISM; GENE; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CELL; LIVER CELL CULTURE; LIVER CELL DAMAGE; NONALCOHOLIC FATTY LIVER; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYMOLOGY; FATTY LIVER; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HEPG2 CELL LINE; LIVER; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; COENZYME A LIGASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FATTY LIVER; FLUORESCENT ANTIBODY TECHNIQUE; HEP G2 CELLS; HEPATOCYTES; HUMANS; IMMUNOENZYME TECHNIQUES; LIPIDS; LIVER; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; UP-REGULATION;

EID: 77954656608     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2010.04.010     Document Type: Article

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