Ethanol-induced cytochrome P4502E1 causes carcinogenic etheno-DNA lesions in alcoholic liver disease

Hepatology

Volumn 50, Issue 2, 2009, Pages 453-461

  Wang, Ying ^a,b,d   Millonig, Gunda ^a   Nair, Jagadeesan ^b   Patsenker, Eleonora ^c   Stickel, Felix ^c   Mueller, Sebastian ^a   Bartsch, Helmut ^b   Seitz, Helmut K ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c UNIVERSITY OF BERN   (Switzerland)

^d HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; ALCOHOL; CLOMETHIAZOLE; CYTOCHROME P450 2E1; 4-HYDROXY-2-NONENAL; ALDEHYDE;

ADULT; AGED; ALCOHOL LIVER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRAIN HEPG2; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; ENZYME ACTIVITY; ENZYME INDUCTION; ETHENO DNA ADDUCT; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIPID PEROXIDATION; LIVER CARCINOGENESIS; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; BIOPSY; LIVER; METABOLISM; MIDDLE AGED; TUMOR CELL LINE; ZUCKER RAT;

ADULT; AGED; ALDEHYDES; ANIMALS; BIOPSY; CELL LINE, TUMOR; CYTOCHROME P-450 CYP2E1; DNA ADDUCTS; ETHANOL; FEMALE; HUMANS; LIVER; LIVER DISEASES, ALCOHOLIC; MALE; MIDDLE AGED; RATS; RATS, ZUCKER;

EID: 68949165996     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.22978     Document Type: Article

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