Recombinant Hep G2 cells that express alcohol dehydrogenase and cytochrome P450 2E1 as a model of ethanol-elicited cytotoxicity

International Journal of Biochemistry and Cell Biology

Volumn 38, Issue 1, 2006, Pages 92-101

  Donohue, Terrence M ^a,b,c   Osna, Natalia A ^a,b   Clemens, Dahn L ^a,b  

^a VA NEBRASKA WESTERN IOWA HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c Jr Liver Study Unit   (United States)

Author keywords

Acetaldehyde; Ethanol; Hep G2 cells; Proteasome; Toxicity

Indexed keywords

ALCOHOL; ALCOHOL DEHYDROGENASE; CASPASE 3; CHYMOTRYPSIN; CYTOCHROME P450 2E1; LACTATE DEHYDROGENASE; LACTIC ACID; PROTEASOME; PYRUVIC ACID;

ALCOHOL CONSUMPTION; APOPTOSIS; ARTICLE; CELL STRAIN HEPG2; CELL TYPE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIVER CELL; PROTEIN DEGRADATION;

ALCOHOL DEHYDROGENASE; ANTIDOTES; APOPTOSIS; CASPASE 3; CASPASES; CELL LINE, TUMOR; CYTOCHROME P-450 CYP2E1; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEPATOCYTES; HUMANS; MICE; PROTEASOME ENDOPEPTIDASE COMPLEX; PYRAZOLES; RATS; SOLVENTS;

MURINAE;

EID: 27544457323     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2005.07.010     Document Type: Article

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