Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine

Hepatology

Volumn 51, Issue 1, 2010, Pages 246-254

  Saito, Chieko ^a   Zwingmann, Claudia ^b   Jaeschke, Hartmut ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; GLUTATHIONE; PARACETAMOL; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CITRIC ACID CYCLE; CONTROLLED STUDY; DNA FRAGMENTATION; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG MEGADOSE; DRUG OVERDOSE; ENERGY METABOLISM; LIVER PROTECTION; LIVER TOXICITY; LOW DRUG DOSE; MALE; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PRIMARY PREVENTION; PRIORITY JOURNAL; THERAPY DELAY;

ACETAMINOPHEN; ACETYLCYSTEINE; ANIMALS; DRUG-INDUCED LIVER INJURY; ENERGY METABOLISM; GLUTATHIONE; MALE; MICE; MICE, INBRED C3H; MITOCHONDRIA, LIVER; OVERDOSE; PEROXYNITROUS ACID; REACTIVE OXYGEN SPECIES; UP-REGULATION;

EID: 73449143152     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.23267     Document Type: Article

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