The discovery of the microsomal ethanol oxidizing system and its physiologic and pathologic role

Drug Metabolism Reviews

Volumn 36, Issue 3-4, 2004, Pages 511-529

  Lieber, Charles S ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Alcohol dehydrogenase; CYP2E1; Microsomal ethanol oxidizing system; Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis

Indexed keywords

ALCOHOL; ALCOHOL DEHYDROGENASE; CATALASE; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; DILINOLEOYLPHOSPHATIDYLCHOLINE; DRUG METABOLIZING ENZYME; FREE RADICAL; GLUTATHIONE; LIVER PROTECTIVE AGENT; MICROSOMAL ETHANOL OXIDIZING SYSTEM; PARACETAMOL; POLYENE PHOSPHATIDYLCHOLINE; RETINOL; SOLVENT; UNCLASSIFIED DRUG;

ALCOHOL CONSUMPTION; ALCOHOL INTOXICATION; ALCOHOL LIVER DISEASE; ALCOHOL OXIDATION; ALCOHOL TOLERANCE; ALCOHOLISM; DRUG ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME MECHANISM; ENZYME REGULATION; FATTY ACID OXIDATION; GLUCONEOGENESIS; HISTOPATHOLOGY; HUMAN; KUPFFER CELL; LIVER CANCER; LIVER CARCINOGENESIS; LIVER CIRRHOSIS; LIVER MICROSOME; LIVER TOXICITY; LONG TERM EXPOSURE; METABOLIC INHIBITION; NONALCOHOLIC FATTY LIVER; NONHUMAN; OXIDATIVE STRESS; REVIEW; SMOOTH ENDOPLASMIC RETICULUM; VITAMIN METABOLISM; XENOBIOTIC METABOLISM;

ALCOHOL DRINKING; ANIMALS; CYTOCHROME P-450 CYP2E1; ETHANOL; FREE RADICALS; HUMANS; MICROSOMES, LIVER; OXIDATION-REDUCTION;

EID: 7544222395     PISSN: 03602532     EISSN: None     Source Type: Journal    
DOI: 10.1081/DMR-200033441     Document Type: Review

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