Enhanced glutathione biosynthetic capacity promotes resistance to As3+-induced apoptosis

Toxicology Letters

Volumn 193, Issue 1, 2010, Pages 33-40

  Thompson, James A ^a   Franklin, Christopher C ^a,b  

^a University of Colorado Denver Anschutz Medical Campus   (United States)

^b UNIVERSITY OF COLORADO CANCER CENTER   (United States)

Author keywords

Apoptosis; Arsenic; Arsenite; GCL; Glutamate cysteine ligase; Glutathione

Indexed keywords

ARSENIC TRIOXIDE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; HOLOENZYME;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME SUBSTRATE COMPLEX; ENZYME SUBUNIT; GENE OVEREXPRESSION; LIVER CELL; MOUSE; NONHUMAN; PEPTIDE ANALYSIS; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; STABLE TRANSFECTION;

ANIMALS; APOPTOSIS; ARSENITES; BLOTTING, WESTERN; CASPASES; CELL LINE, TUMOR; CYTOCHROMES C; CYTOPLASM; ENZYME ACTIVATION; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; INDICATORS AND REAGENTS; MICE;

EID: 75749094680     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.12.004     Document Type: Article

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