메뉴 건너뛰기




Volumn 43, Issue 3, 2011, Pages 198-211

Sirtuin 1 in lipid metabolism and obesity

Author keywords

Metabolic syndrome; metabolism; SIRT1

Indexed keywords

ADENYLATE KINASE; ADIPONECTIN; FATTY ACID; SIRTUIN 1;

EID: 79953898189     PISSN: 07853890     EISSN: 13652060     Source Type: Journal    
DOI: 10.3109/07853890.2010.547211     Document Type: Article
Times cited : (236)

References (115)
  • 1
    • 17144380822 scopus 로고    scopus 로고
    • The metabolic syndrome
    • DOI 10.1016/S0140-6736(05)66378-7
    • Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet. 2005;365:1415-28. (Pubitemid 40523737)
    • (2005) Lancet , vol.365 , Issue.9468 , pp. 1415-1428
    • Eckel, R.H.1    Grundy, S.M.2    Zimmet, P.Z.3
  • 3
    • 17144429302 scopus 로고    scopus 로고
    • Calorie restriction, SIRT1 and metabolism: Understanding longevity
    • DOI 10.1038/nrm1616
    • Bordone L, Guarente L. Calorie restriction, SIRT1 and metabolism: understanding longevity. Nat Rev Mol Cell Biol. 2005;6:298-305. (Pubitemid 40516896)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.4 , pp. 298-305
    • Bordone, L.1    Guarente, L.2
  • 4
    • 33645470211 scopus 로고    scopus 로고
    • Drug therapy of the metabolic syndrome: Minimizing the emerging crisis in polypharmacy
    • Grundy SM. Drug therapy of the metabolic syndrome: minimizing the emerging crisis in polypharmacy. Nat Rev Drug Discov. 2006;5:295-309.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 295-309
    • Grundy, S.M.1
  • 5
    • 55249098186 scopus 로고    scopus 로고
    • White adipose tissue as endocrine organ and its role in obesity
    • Vazquez-Vela ME, Torres N, Tovar AR. White adipose tissue as endocrine organ and its role in obesity. Arch Med Res. 2008;39:715-28.
    • (2008) Arch Med Res , vol.39 , pp. 715-28
    • Vazquez-Vela, M.E.1    Torres, N.2    Tovar, A.R.3
  • 6
    • 1842506529 scopus 로고    scopus 로고
    • The current biology of resistin
    • DOI 10.1111/j.1365-2796.2004.01306.x
    • Steppan CM, Lazar MA. The current biology of resistin. J Intern Med. 2004;255:439-47. (Pubitemid 38446357)
    • (2004) Journal of Internal Medicine , vol.255 , Issue.4 , pp. 439-447
    • Steppan, C.M.1    Lazar, M.A.2
  • 7
    • 4344607526 scopus 로고    scopus 로고
    • Endocrine regulation of energy metabolism: Review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin
    • DOI 10.1373/clinchem.2004.032482
    • Meier U, Gressner AM. Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin. Clin Chem. 2004;50:1511-25. (Pubitemid 39121218)
    • (2004) Clinical Chemistry , vol.50 , Issue.9 , pp. 1511-1525
    • Meier, U.1    Gressner, A.M.2
  • 8
    • 44449124672 scopus 로고    scopus 로고
    • The secretory function of adipocytes in the physiology of white adipose tissue
    • DOI 10.1002/jcp.21386
    • Wang P, Mariman E, Renes J, Keijer J. The secretory function of adipocytes in the physiology of white adipose tissue. J Cell Physiol. 2008;216:3-13. (Pubitemid 351813090)
    • (2008) Journal of Cellular Physiology , vol.216 , Issue.1 , pp. 3-13
    • Wang, P.1    Mariman, E.2    Renes, J.3    Keijer, J.4
  • 10
    • 0034677535 scopus 로고    scopus 로고
    • Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
    • DOI 10.1038/35001622
    • Imai S, Armstrong CM, Kaeberlein M, Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature. 2000;403:795-800. (Pubitemid 30111843)
    • (2000) Nature , vol.403 , Issue.6771 , pp. 795-800
    • Imai, S.-I.1    Armstrong, C.M.2    Kaeberlein, M.3    Guarente, L.4
  • 13
    • 3943054839 scopus 로고    scopus 로고
    • The Sir2 family of protein deacetylases
    • DOI 10.1146/annurev.biochem.73.011303.073651
    • Blander G, Guarente L. The Sir2 family of protein deacetylases. Annu Rev Biochem. 2004;73:417-35. (Pubitemid 39050375)
    • (2004) Annual Review of Biochemistry , vol.73 , pp. 417-435
    • Blander, G.1    Guarente, L.2
  • 15
    • 33645774382 scopus 로고    scopus 로고
    • Increased life span due to calorie restriction in respiratory-defi cient yeast
    • author reply e4
    • Lin SJ, Guarente L. Increased life span due to calorie restriction in respiratory-defi cient yeast. PLoS Genet. 2006;2:e33; author reply e4.
    • (2006) PLoS Genet , vol.2
    • Lin, S.J.1    Guarente, L.2
  • 17
    • 4944245398 scopus 로고    scopus 로고
    • Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin
    • DOI 10.1016/j.molcel.2004.08.031, PII S1097276504005180
    • Vaquero A, Scher M, Lee D, Erdjument-Bromage H, Tempst P, Reinberg D. Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. Molecular cell. 2004;16:93-105. (Pubitemid 39330155)
    • (2004) Molecular Cell , vol.16 , Issue.1 , pp. 93-105
    • Vaquero, A.1    Scher, M.2    Lee, D.3    Erdjument-Bromage, H.4    Tempst, P.5    Reinberg, D.6
  • 18
    • 66049160126 scopus 로고    scopus 로고
    • The ageing epigenome: Damaged beyond repair?
    • Sinclair DA, Oberdoerffer P. The ageing epigenome: damaged beyond repair? Ageing Res Rev. 2009;8:189-98.
    • (2009) Ageing Res Rev , vol.8 , pp. 189-98
    • Sinclair, D.A.1    Oberdoerffer, P.2
  • 19
  • 20
    • 33846861558 scopus 로고    scopus 로고
    • Comparison of body fat composition and serum adiponectin levels in diabetic obesity and non-diabetic obesity
    • Kim C, Park J, Kang E, Ahn C, Cha B, Lim S, et al. Comparison of body fat composition and serum adiponectin levels in diabetic obesity and non-diabetic obesity. Obesity (Silver Spring). 2006;14:1164-71. (Pubitemid 46219682)
    • (2006) Obesity , vol.14 , Issue.7 , pp. 1164-1171
    • Kim, C.1    Park, J.2    Park, J.3    Kang, E.4    Ahn, C.5    Cha, B.6    Lim, S.7    Kim, K.8    Lee, H.9
  • 22
    • 0034703217 scopus 로고    scopus 로고
    • Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
    • Lin SJ, Defossez PA, Guarente L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science. 2000;289:2126-8.
    • (2000) Science , vol.289 , pp. 2126-8
    • Lin, S.J.1    Defossez, P.A.2    Guarente, L.3
  • 23
    • 28844469898 scopus 로고    scopus 로고
    • Medicine: Increase in activity during calorie restriction requires Sirt1
    • DOI 10.1126/science.1118357
    • Chen D, Steele AD, Lindquist S, Guarente L. Increase in activity during calorie restriction requires Sirt1. Science. 2005;310:1641. (Pubitemid 41780779)
    • (2005) Science , vol.310 , Issue.5754 , pp. 1641
    • Chen, D.1    Steele, A.D.2    Lindquist, S.3    Guarente, L.4
  • 25
    • 72849130743 scopus 로고    scopus 로고
    • Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction
    • Cohen DE, Supinski AM, Bonkowski MS, Donmez G, Guarente LP. Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction. Genes Dev. 2009; 23:2812-7.
    • (2009) Genes Dev , vol.23 , pp. 2812-7
    • Cohen, D.E.1    Supinski, A.M.2    Bonkowski, M.S.3    Donmez, G.4    Guarente, L.P.5
  • 27
    • 65549139675 scopus 로고    scopus 로고
    • Regulation of the aging process by autophagy
    • Salminen A, Kaarniranta K. Regulation of the aging process by autophagy. Trends Mol Med. 2009;15:217-24.
    • (2009) Trends Mol Med , vol.15 , pp. 217-24
    • Salminen, A.1    Kaarniranta, K.2
  • 28
    • 77954813618 scopus 로고    scopus 로고
    • SIRTing out the link between autophagy and ageing
    • Goligorsky MS. SIRTing out the link between autophagy and ageing. Nephrol Dial Transplant. 2010;25:2434-6.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 2434-6
    • Goligorsky, M.S.1
  • 29
    • 77954623119 scopus 로고    scopus 로고
    • Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: Implication in pathogenesis of COPD
    • Hwang JW, Chung S, Sundar IK, Yao H, Arunachalam G, McBurney MW, et al. Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD. Arch Biochem Biophys. 2010;500:203-9.
    • (2010) Arch Biochem Biophys. , vol.500 , pp. 203-9
    • Hwang, J.W.1    Chung, S.2    Sundar, I.K.3    Yao, H.4    Arunachalam, G.5    McBurney, M.W.6
  • 30
    • 77957294848 scopus 로고    scopus 로고
    • Autophagic pathways and metabolic stress
    • Kaushik S, Singh R, Cuervo AM. Autophagic pathways and metabolic stress. Diabetes Obes Metab. 2010;12 Suppl 2: 4-14.
    • (2010) Diabetes Obes Metab , vol.12 , Issue.SUPPL. 2 , pp. 4-14
    • Kaushik, S.1    Singh, R.2    Cuervo, A.M.3
  • 40
    • 33845868198 scopus 로고    scopus 로고
    • Sirtuins as potential targets for metabolic syndrome
    • DOI 10.1038/nature05486, PII NATURE05486
    • Guarente L. Sirtuins as potential targets for metabolic syndrome. Nature. 2006;444:868-74. (Pubitemid 46024994)
    • (2006) Nature , vol.444 , Issue.7121 , pp. 868-874
    • Guarente, L.1
  • 41
    • 12244302878 scopus 로고    scopus 로고
    • Influence of age and caloric restriction on liver glycolytic enzyme activities and metabolite concentrations in mice
    • DOI 10.1016/S0531-5565(02)00203-6, PII S0531556502002036
    • Hagopian K, Ramsey JJ, Weindruch R. Infl uence of age and caloric restriction on liver glycolytic enzyme activities and metabolite concentrations in mice. Exp Gerontol. 2003;38: 253-66. (Pubitemid 36170320)
    • (2003) Experimental Gerontology , vol.38 , Issue.3 , pp. 253-266
    • Hagopian, K.1    Ramsey, J.J.2    Weindruch, R.3
  • 44
    • 77249156847 scopus 로고    scopus 로고
    • Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle
    • Canto C, Jiang LQ, Deshmukh AS, Mataki C, Coste A, Lagouge M, et al. Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle. Cell Metab. 2010;11:213-9.
    • (2010) Cell Metab. , vol.11 , pp. 213-9
    • Canto, C.1    Jiang, L.Q.2    Deshmukh, A.S.3    Mataki, C.4    Coste, A.5    Lagouge, M.6
  • 45
    • 77951872309 scopus 로고    scopus 로고
    • Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1
    • Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, et al. Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1. Nature. 2010;464:1313-9.
    • (2010) Nature , vol.464 , pp. 1313-9
    • Iwabu, M.1    Yamauchi, T.2    Okada-Iwabu, M.3    Sato, K.4    Nakagawa, T.5    Funata, M.6
  • 46
    • 14544282413 scopus 로고    scopus 로고
    • Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
    • DOI 10.1038/nature03354
    • Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature. 2005;434:113-8. (Pubitemid 40349395)
    • (2005) Nature , vol.434 , Issue.7029 , pp. 113-118
    • Rodgers, J.T.1    Lerin, C.2    Haas, W.3    Gygi, S.P.4    Spiegelman, B.M.5    Puigserver, P.6
  • 47
    • 76649085804 scopus 로고    scopus 로고
    • Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice
    • Escande C, Chini CC, Nin V, Dykhouse KM, Novak CM, Levine J, et al. Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice. J Clin Invest. 2010;120:545-58.
    • (2010) J Clin Invest , vol.120 , pp. 545-58
    • Escande, C.1    Chini, C.C.2    Nin, V.3    Dykhouse, K.M.4    Novak, C.M.5    Levine, J.6
  • 51
    • 0025768055 scopus 로고
    • The role of the liver in metabolic homeostasis: Implications for inborn errors of metabolism
    • van den Berghe G. The role of the liver in metabolic homeostasis: implications for inborn errors of metabolism. J Inherit Metab Dis. 1991;14:407-20.
    • (1991) J Inherit Metab Dis , vol.14 , pp. 407-20
    • Van Den Berghe, G.1
  • 52
    • 56249100986 scopus 로고    scopus 로고
    • A fasting inducible switch modulates gluco-neogenesis via activator/coactivator exchange
    • Liu Y, Dentin R, Chen D, Hedrick S, Ravnskjaer K, Schenk S, et al. A fasting inducible switch modulates gluco-neogenesis via activator/coactivator exchange. Nature. 2008; 456:269-73.
    • (2008) Nature , vol.456 , pp. 269-73
    • Liu, Y.1    Dentin, R.2    Chen, D.3    Hedrick, S.4    Ravnskjaer, K.5    Schenk, S.6
  • 53
    • 63449112017 scopus 로고    scopus 로고
    • Hepatocyte-specifi c deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and infl ammation
    • Purushotham A, Schug TT, Xu Q, Surapureddi S, Guo X, Li X. Hepatocyte-specifi c deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and infl ammation. Cell Metab. 2009;9:327-38.
    • (2009) Cell Metab , vol.9 , pp. 327-38
    • Purushotham, A.1    Schug, T.T.2    Xu, Q.3    Surapureddi, S.4    Guo, X.5    Li, X.6
  • 54
    • 77953292242 scopus 로고    scopus 로고
    • Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5
    • Dominy JE Jr, Lee Y, Gerhart-Hines Z, Puigserver P. Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5. Biochim Biophys Acta. 2010;1804:1676-83.
    • (2010) Biochim Biophys Acta. , vol.1804 , pp. 1676-83
    • Dominy Jr., J.E.1    Lee, Y.2    Gerhart-Hines, Z.3    Puigserver, P.4
  • 55
    • 34948883324 scopus 로고    scopus 로고
    • SIRT1 deacetylates and positively regulates the nuclear receptor LXR
    • DOI 10.1016/j.molcel.2007.07.032, PII S109727650700620X
    • Li X, Zhang S, Blander G, Tse JG, Krieger M, Guarente L. SIRT1 deacetylates and positively regulates the nuclear receptor LXR. Mol Cell. 2007;28:91-106. (Pubitemid 47531974)
    • (2007) Molecular Cell , vol.28 , Issue.1 , pp. 91-106
    • Li, X.1    Zhang, S.2    Blander, G.3    Tse, J.G.4    Krieger, M.5    Guarente, L.6
  • 56
    • 70350606061 scopus 로고    scopus 로고
    • FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states
    • Kemper JK, Xiao Z, Ponugoti B, Miao J, Fang S, Kanamaluru D, et al. FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states. Cell Metab. 2009;10: 392-404.
    • (2009) Cell Metab , vol.10 , pp. 392-404
    • Kemper, J.K.1    Xiao, Z.2    Ponugoti, B.3    Miao, J.4    Fang, S.5    Kanamaluru, D.6
  • 57
    • 0029562554 scopus 로고
    • The RXR heterodimers and orphan receptors
    • DOI 10.1016/0092-8674(95)90200-7
    • Mangelsdorf DJ, Evans RM. The RXR heterodimers and orphan receptors. Cell. 1995;83:841-50. (Pubitemid 26006526)
    • (1995) Cell , vol.83 , Issue.6 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 58
    • 50649112638 scopus 로고    scopus 로고
    • SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase
    • Hou X, Xu S, Maitland-Toolan KA, Sato K, Jiang B, Ido Y, et al. SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase. J Biol Chem. 2008; 283:20015-26.
    • (2008) J Biol Chem , vol.283 , pp. 20015-26
    • Hou, X.1    Xu, S.2    Maitland-Toolan, K.A.3    Sato, K.4    Jiang, B.5    Ido, Y.6
  • 60
    • 48349108293 scopus 로고    scopus 로고
    • Genome-wide coactivation analysis of PGC-1alpha identifi es BAF60a as a regulator of hepatic lipid metabolism
    • Li S, Liu C, Li N, Hao T, Han T, Hill DE, et al. Genome-wide coactivation analysis of PGC-1alpha identifi es BAF60a as a regulator of hepatic lipid metabolism. Cell Metab. 2008;8: 105-17.
    • (2008) Cell Metab , vol.8 , pp. 105-17
    • Li, S.1    Liu, C.2    Li, N.3    Hao, T.4    Han, T.5    Hill, D.E.6
  • 61
    • 35548996710 scopus 로고    scopus 로고
    • DisSIRTing on LXR and cholesterol metabolism
    • DOI 10.1016/j.cmet.2007.10.003, PII S1550413107002963
    • Feige JN, Auwerx J. DisSIRTing on LXR and cholesterol metabolism. Cell Metab. 2007;6:343-5. (Pubitemid 350012003)
    • (2007) Cell Metabolism , vol.6 , Issue.5 , pp. 343-345
    • Feige, J.N.1    Auwerx, J.2
  • 62
    • 72749086098 scopus 로고    scopus 로고
    • Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: What a long, strange tRIP it's been
    • Osborne TF, Espenshade PJ. Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been. Genes Dev. 2009;23: 2578-91.
    • (2009) Genes Dev , vol.23 , pp. 2578-91
    • Osborne, T.F.1    Espenshade, P.J.2
  • 63
    • 77954488637 scopus 로고    scopus 로고
    • Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP
    • Walker AK, Yang F, Jiang K, Ji JY, Watts JL, Purushotham A, et al. Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Genes Dev. 2010;24:1403-17.
    • (2010) Genes Dev. , vol.24 , pp. 1403-17
    • Walker, A.K.1    Yang, F.2    Jiang, K.3    Ji, J.Y.4    Watts, J.L.5    Purushotham, A.6
  • 64
    • 77958595135 scopus 로고    scopus 로고
    • SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism
    • Ponugoti B, Kim DH, Xiao Z, Smith Z, Miao J, Zang M, et al. SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism. J Biol Chem. 2010;285:33959-70.
    • (2010) J Biol Chem. , vol.285 , pp. 33959-70
    • Ponugoti, B.1    Kim, D.H.2    Xiao, Z.3    Smith, Z.4    Miao, J.5    Zang, M.6
  • 67
    • 33845866857 scopus 로고    scopus 로고
    • Infl ammation and metabolic disorders
    • Hotamisligil GS. Infl ammation and metabolic disorders. Nature. 2006;444:860-7.
    • (2006) Nature , vol.444 , pp. 860-7
    • Hotamisligil, G.S.1
  • 69
    • 77954672503 scopus 로고    scopus 로고
    • Adipose tissue macrophages: Their role in adipose tissue remodeling
    • Suganami T, Ogawa Y. Adipose tissue macrophages: their role in adipose tissue remodeling. J Leukoc Biol. 2010;88:33-9.
    • (2010) J Leukoc Biol. , vol.88 , pp. 33-9
    • Suganami, T.1    Ogawa, Y.2
  • 71
    • 42649146208 scopus 로고    scopus 로고
    • SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease
    • DOI 10.1164/rccm.200708-1269OC
    • Rajendrasozhan S, Yang SR, Kinnula VL, Rahman I. SIRT1, an antiinfl ammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2008;177:861-70. (Pubitemid 351600664)
    • (2008) American Journal of Respiratory and Critical Care Medicine , vol.177 , Issue.8 , pp. 861-870
    • Rajendrasozhan, S.1    Yang, S.-R.2    Kinnula, V.L.3    Rahman, I.4
  • 72
  • 74
    • 77956677458 scopus 로고    scopus 로고
    • Myeloid deletion of SIRT1 induces infl am-matory signaling in response to environmental stress
    • Schug TT, Xu Q, Gao H, Peres-da-Silva A, Draper DW, Fessler MB, et al. Myeloid deletion of SIRT1 induces infl am-matory signaling in response to environmental stress. Mol Cell Biol. 2010;30:4712-21.
    • (2010) Mol Cell Biol. , vol.30 , pp. 4712-21
    • Schug, T.T.1    Xu, Q.2    Gao, H.3    Peres-Da-Silva, A.4    Draper, D.W.5    Fessler, M.B.6
  • 75
    • 3242719545 scopus 로고    scopus 로고
    • Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase
    • DOI 10.1038/sj.emboj.7600244
    • Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA, et al. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 2004;23:2369-80. (Pubitemid 38954844)
    • (2004) EMBO Journal , vol.23 , Issue.12 , pp. 2369-2380
    • Yeung, F.1    Hoberg, J.E.2    Ramsey, C.S.3    Keller, M.D.4    Jones, D.R.5    Frye, R.A.6    Mayo, M.W.7
  • 77
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • DOI 10.1038/nri978
    • Gordon S. Alternative activation of macrophages. Nat Rev Immunol. 2003;3:23-35. (Pubitemid 37328697)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.1 , pp. 23-35
    • Gordon, S.1
  • 78
    • 54549096762 scopus 로고    scopus 로고
    • Mechanisms of macrophage activation in obesity-induced insulin resistance
    • Odegaard JI, Chawla A. Mechanisms of macrophage activation in obesity-induced insulin resistance. Nat Clin Pract Endocrinol Metab. 2008;4:619-26.
    • (2008) Nat Clin Pract Endocrinol Metab , vol.4 , pp. 619-26
    • Odegaard, J.I.1    Chawla, A.2
  • 79
    • 50649097541 scopus 로고    scopus 로고
    • Fat and beyond: The diverse biology of PPARgamma
    • Tontonoz P, Spiegelman BM. Fat and beyond: the diverse biology of PPARgamma. Annu Rev Biochem. 2008;77: 289-312.
    • (2008) Annu Rev Biochem , vol.77 , pp. 289-312
    • Tontonoz, P.1    Spiegelman, B.M.2
  • 80
    • 1942518840 scopus 로고    scopus 로고
    • PPARs and the complex journey to obesity
    • DOI 10.1038/nm1025
    • Evans RM, Barish GD, Wang YX. PPARs and the complex journey to obesity. Nat Med. 2004;10:355-61. (Pubitemid 38508511)
    • (2004) Nature Medicine , vol.10 , Issue.4 , pp. 355-361
    • Evans, R.M.1    Barish, G.D.2    Wang, Y.-X.3
  • 81
    • 0037942739 scopus 로고    scopus 로고
    • Extended longevity in mice lacking the insulin receptor in adipose tissue
    • DOI 10.1126/science.1078223
    • Bluher M, Kahn BB, Kahn CR. Extended longevity in mice lacking the insulin receptor in adipose tissue. Science. 2003;299:572-4. (Pubitemid 36135156)
    • (2003) Science , vol.299 , Issue.5606 , pp. 572-574
    • Bluher, M.1    Kahn, B.B.2    Kahn, C.R.3
  • 83
    • 77956644726 scopus 로고    scopus 로고
    • SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity
    • Ramadori G, Fujikawa T, Fukuda M, Anderson J, Morgan DA, Mostoslavsky R, et al. SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity. Cell Metab. 2010;12:78-87.
    • (2010) Cell Metab , vol.12 , pp. 78-87
    • Ramadori, G.1    Fujikawa, T.2    Fukuda, M.3    Anderson, J.4    Morgan, D.A.5    Mostoslavsky, R.6
  • 84
    • 54849425547 scopus 로고    scopus 로고
    • Specifi c SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation
    • Feige JN, Lagouge M, Canto C, Strehle A, Houten SM, Milne JC, et al. Specifi c SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation. Cell Metab. 2008;8:347-58.
    • (2008) Cell Metab , vol.8 , pp. 347-58
    • Feige, J.N.1    Lagouge, M.2    Canto, C.3    Strehle, A.4    Houten, S.M.5    Milne, J.C.6
  • 85
    • 33748931457 scopus 로고    scopus 로고
    • Central nervous system control of food intake and body weight
    • DOI 10.1038/nature05026, PII NATURE05026
    • Morton GJ, Cummings DE, Baskin DG, Barsh GS, Schwartz MW. Central nervous system control of food intake and body weight. Nature. 2006;443:289-95. (Pubitemid 44435142)
    • (2006) Nature , vol.443 , Issue.7109 , pp. 289-295
    • Morton, G.J.1    Cummings, D.E.2    Baskin, D.G.3    Barsh, G.S.4    Schwartz, M.W.5
  • 87
    • 77955344258 scopus 로고    scopus 로고
    • SIRT1 promotes the central adaptive response to diet restriction through activation of the dorso-medial and lateral nuclei of the hypothalamus
    • Satoh A, Brace CS, Ben-Josef G, West T, Wozniak DF, Holtzman DM, et al. SIRT1 promotes the central adaptive response to diet restriction through activation of the dorso-medial and lateral nuclei of the hypothalamus. J Neurosci. 2010;30:10220-32.
    • (2010) J Neurosci. , vol.30 , pp. 10220-32
    • Satoh, A.1    Brace, C.S.2    Ben-Josef, G.3    West, T.4    Wozniak, D.F.5    Holtzman, D.M.6
  • 88
    • 77956241193 scopus 로고    scopus 로고
    • Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: Roles for Sirt1 in neuronal fi ring and synaptic plasticity
    • Dietrich MO, Antunes C, Geliang G, Liu ZW, Borok E, Nie Y, et al. Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal fi ring and synaptic plasticity. J Neurosci. 2010;30: 11815-25.
    • (2010) J Neurosci. , vol.30 , pp. 11815-25
    • Dietrich, M.O.1    Antunes, C.2    Geliang, G.3    Liu, Z.W.4    Borok, E.5    Nie, Y.6
  • 90
    • 33845611615 scopus 로고    scopus 로고
    • Interplay of circadian clocks and metabolic rhythms
    • DOI 10.1146/annurev.genet.40.110405.090603
    • Wijnen H, Young MW. Interplay of circadian clocks and metabolic rhythms. Annu Rev Genet. 2006;40:409-48. (Pubitemid 44956792)
    • (2006) Annual Review of Genetics , vol.40 , pp. 409-448
    • Wijnen, H.1    Young, M.W.2
  • 92
    • 14044264801 scopus 로고    scopus 로고
    • BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis
    • Rudic RD, McNamara P, Curtis AM, Boston RC, Panda S, Hogenesch JB, et al. BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis. PLoS Biol. 2004;2:e377.
    • (2004) PLoS Biol , vol.2
    • Rudic, R.D.1    McNamara, P.2    Curtis, A.M.3    Boston, R.C.4    Panda, S.5    Hogenesch, J.B.6
  • 94
    • 58149464684 scopus 로고    scopus 로고
    • High-fat diet delays and fasting advances the circadian expression of adiponectin signaling components in mouse liver
    • Barnea M, Madar Z, Froy O. High-fat diet delays and fasting advances the circadian expression of adiponectin signaling components in mouse liver. Endocrinology. 2009;150: 161-8.
    • (2009) Endocrinology , vol.150 , pp. 161-8
    • Barnea, M.1    Madar, Z.2    Froy, O.3
  • 95
    • 65549128208 scopus 로고    scopus 로고
    • Circadian rhythms. A circadian loop asSIRTs itself
    • Wijnen H. Circadian rhythms. A circadian loop asSIRTs itself. Science. 2009;324:598-9.
    • (2009) Science , vol.324 , pp. 598-9
    • Wijnen, H.1
  • 96
    • 33646145721 scopus 로고    scopus 로고
    • Circadian regulator CLOCK is a histone acetyltransferase
    • Doi M, Hirayama J, Sassone-Corsi P. Circadian regulator CLOCK is a histone acetyltransferase. Cell. 2006;125: 497-508.
    • (2006) Cell , vol.125 , pp. 497-508
    • Doi, M.1    Hirayama, J.2    Sassone-Corsi, P.3
  • 101
    • 38749132992 scopus 로고    scopus 로고
    • Negative regulation of the deacetylase SIRT1 by DBC1
    • DOI 10.1038/nature06515, PII NATURE06515
    • Zhao W, Kruse JP, Tang Y, Jung SY, Qin J, Gu W. Negative regulation of the deacetylase SIRT1 by DBC1. Nature. 2008;451:587-90. (Pubitemid 351186268)
    • (2008) Nature , vol.451 , Issue.7178 , pp. 587-590
    • Zhao, W.1    Kruse, J.-P.2    Tang, Y.3    Jung, S.Y.4    Qin, J.5    Gu, W.6
  • 102
    • 38749088678 scopus 로고    scopus 로고
    • DBC1 is a negative regulator of SIRT1
    • DOI 10.1038/nature06500, PII NATURE06500
    • Kim JE, Chen J, Lou Z. DBC1 is a negative regulator of SIRT1. Nature. 2008;451:583-6. (Pubitemid 351186264)
    • (2008) Nature , vol.451 , Issue.7178 , pp. 583-586
    • Kim, J.-E.1    Chen, J.2    Lou, Z.3
  • 103
    • 35349011726 scopus 로고    scopus 로고
    • Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity
    • Kim EJ, Kho JH, Kang MR, Um SJ. Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity. Mol Cell. 2007;28:277-90.
    • (2007) Mol Cell , vol.28 , pp. 277-90
    • Kim, E.J.1    Kho, J.H.2    Kang, M.R.3    Um, S.J.4
  • 104
    • 35748962613 scopus 로고    scopus 로고
    • SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress
    • DOI 10.1038/ncb1645, PII NCB1645
    • Yang Y, Fu W, Chen J, Olashaw N, Zhang X, Nicosia SV, et al. SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress. Nat Cell Biol. 2007;9:1253-62. (Pubitemid 350042357)
    • (2007) Nature Cell Biology , vol.9 , Issue.11 , pp. 1253-1262
    • Yang, Y.1    Fu, W.2    Chen, J.3    Olashaw, N.4    Zhang, X.5    Nicosia, S.V.6    Bhalla, K.7    Bai, W.8
  • 106
    • 69949138641 scopus 로고    scopus 로고
    • CK2 is the regulator of SIRT1 substrate-binding affi nity, deacetylase activity and cellular response to DNA-damage
    • Kang H, Jung JW, Kim MK, Chung JH. CK2 is the regulator of SIRT1 substrate-binding affi nity, deacetylase activity and cellular response to DNA-damage. PloS One. 2009;4: e6611.
    • (2009) PloS One , vol.4
    • Kang, H.1    Jung, J.W.2    Kim, M.K.3    Chung, J.H.4
  • 108
    • 77951225449 scopus 로고    scopus 로고
    • DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1
    • Guo X, Williams JG, Schug TT, Li X. DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1. J Biol Chem. 2010;285:13223-32.
    • (2010) J Biol Chem. , vol.285 , pp. 13223-32
    • Guo, X.1    Williams, J.G.2    Schug, T.T.3    Li, X.4
  • 109
    • 77949363859 scopus 로고    scopus 로고
    • DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping
    • Kurabayashi N, Hirota T, Sakai M, Sanada K, Fukada Y. DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping. Mol Cell Biol. 2010;30: 1757-68.
    • (2010) Mol Cell Biol. , vol.30 , pp. 1757-68
    • Kurabayashi, N.1    Hirota, T.2    Sakai, M.3    Sanada, K.4    Fukada, Y.5
  • 114
    • 55749101261 scopus 로고    scopus 로고
    • Polymorphisms in the adiponutrin gene are associated with increased insulin secretion and obesity
    • Johansson LE, Lindblad U, Larsson CA, Rastam L, Ridderstrale M. Polymorphisms in the adiponutrin gene are associated with increased insulin secretion and obesity. Eur J Endocrinol. 2008;159:577-83.
    • (2008) Eur J Endocrinol , vol.159 , pp. 577-83
    • Johansson, L.E.1    Lindblad, U.2    Larsson, C.A.3    Rastam, L.4    Ridderstrale, M.5
  • 115
    • 77954868317 scopus 로고    scopus 로고
    • Prediabetes and prehypertension in disease free obese adults correlate with an exacerbated systemic proinfl ammatory milieu
    • Gupta AK, Johnson WD. Prediabetes and prehypertension in disease free obese adults correlate with an exacerbated systemic proinfl ammatory milieu. J Infl amm (Lond). 2010; 7:36.
    • (2010) J Infl Amm (Lond). , vol.7 , pp. 36
    • Gupta, A.K.1    Johnson, W.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.