-
1
-
-
51349156218
-
Insulin sensitivity: Modulation by nutrients and inflammation
-
Schenk, S., Saberi, M., Olefsky, J. M. (2008) Insulin sensitivity: modulation by nutrients and inflammation. J. Clin. Invest. 118, 2992-3002.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 2992-3002
-
-
Schenk, S.1
Saberi, M.2
Olefsky, J.M.3
-
2
-
-
33845866857
-
Inflammation and metabolic disorders
-
Hotamisligil, G. S. (2006) Inflammation and metabolic disorders. Nature 444, 860-867.
-
(2006)
Nature
, vol.444
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
3
-
-
19044393872
-
Adipose tissue, inflammation, and cardiovascular disease
-
DOI 10.1161/01.RES.0000163635.62927.34
-
Berg, A. H., Scherer, P. E. (2005) Adipose tissue, inflammation, and cardiovascular disease. Circ. Res. 96, 939-949. (Pubitemid 40712793)
-
(2005)
Circulation Research
, vol.96
, Issue.9
, pp. 939-949
-
-
Berg, A.H.1
Scherer, P.E.2
-
4
-
-
69249205739
-
Obesity, inflammation, and atherosclerosis
-
Rocha, V. Z., Libby, P. (2009) Obesity, inflammation, and atherosclerosis. Nat. Rev. Cardiol. 6, 399-409.
-
(2009)
Nat. Rev. Cardiol.
, vol.6
, pp. 399-409
-
-
Rocha, V.Z.1
Libby, P.2
-
5
-
-
0032779351
-
Molecular mechanism of metabolic syndrome X: Contribution of adipocytokines adipocyte-derived bioactive substances
-
Matsuzawa, Y., Funahashi, T., Nakamura, T. (1999) Molecular mechanism of metabolic syndrome X: contribution of adipocytokines adipocyte-derived bioactive substances. Ann. N. Y. Acad. Sci. 892, 146-154.
-
(1999)
Ann. N. Y. Acad. Sci.
, vol.892
, pp. 146-154
-
-
Matsuzawa, Y.1
Funahashi, T.2
Nakamura, T.3
-
6
-
-
33745834319
-
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
-
DOI 10.1172/JCI29126
-
Kadowaki, T., Yamauchi, T., Kubota, N., Hara, K., Ueki, K., Tobe, K. (2006) Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J. Clin. Invest. 116, 1784-1792. (Pubitemid 44033298)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.7
, pp. 1784-1792
-
-
Kadowaki, T.1
Yamauchi, T.2
Kubota, N.3
Hara, K.4
Ueki, K.5
Tobe, K.6
-
7
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R. L., Ferrante Jr., A. W. (2003) Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest. 112, 1796-1808.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante Jr., A.W.6
-
8
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., Chen, H. (2003) Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest. 112, 1821-1830.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
9
-
-
7744226149
-
Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects
-
Clement, K., Viguerie, N., Poitou, C., Carette, C., Pelloux, V., Curat, C. A., Sicard, A., Rome, S., Benis, A., Zucker, J. D., Vidal, H., Laville, M., Barsh, G. S., Basdevant, A., Stich, V., Cancello, R., Langin, D. (2004) Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects. FASEB J. 18, 1657-1669.
-
(2004)
FASEB J.
, vol.18
, pp. 1657-1669
-
-
Clement, K.1
Viguerie, N.2
Poitou, C.3
Carette, C.4
Pelloux, V.5
Curat, C.A.6
Sicard, A.7
Rome, S.8
Benis, A.9
Zucker, J.D.10
Vidal, H.11
Laville, M.12
Barsh, G.S.13
Basdevant, A.14
Stich, V.15
Cancello, R.16
Langin, D.17
-
10
-
-
3042710511
-
-
Washington, DC, USA, American Physiology Society
-
Wasserman, F. (1965) Handbook of Physiology. Washington, DC, USA, American Physiology Society.
-
(1965)
Handbook of Physiology
-
-
Wasserman, F.1
-
11
-
-
30044449982
-
Resolution of inflammation: The beginning programs the end
-
Serhan, C. N., Savill, J. (2005) Resolution of inflammation: the beginning programs the end. Nat. Immunol. 6, 1191-1197.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1191-1197
-
-
Serhan, C.N.1
Savill, J.2
-
12
-
-
47949099098
-
Origin and physiological roles of inflammation
-
Medzhitov, R. (2008) Origin and physiological roles of inflammation. Nature 454, 428-435.
-
(2008)
Nature
, vol.454
, pp. 428-435
-
-
Medzhitov, R.1
-
13
-
-
34249719581
-
Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels
-
Nishimura, S., Manabe, I., Nagasaki, M., Hosoya, Y., Yamashita, H., Fujita, H., Ohsugi, M., Tobe, K., Kadowaki, T., Nagai, R., Sigiura, S. (2007) Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels. Diabetes 56, 1517-1526.
-
(2007)
Diabetes
, vol.56
, pp. 1517-1526
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
Hosoya, Y.4
Yamashita, H.5
Fujita, H.6
Ohsugi, M.7
Tobe, K.8
Kadowaki, T.9
Nagai, R.10
Sigiura, S.11
-
14
-
-
38849118568
-
In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue
-
Nishimura, S., Manabe, I., Nagasaki, M., Seo, K., Yamashita, H., Hosoya, Y., Ohsugi, M., Tobe, K., Kadowaki, T., Nagai, R., Sigiura, S. (2008) In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue. J. Clin. Invest. 118, 710-721.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 710-721
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
Seo, K.4
Yamashita, H.5
Hosoya, Y.6
Ohsugi, M.7
Tobe, K.8
Kadowaki, T.9
Nagai, R.10
Sigiura, S.11
-
15
-
-
31044456529
-
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
-
Weisberg, S. P., Hunter, D., Huber, R., Lemieux, J., Slaymaker, S., Vaddi, K., Charo, I., Leibel, R. L., Ferrante Jr., A. W. (2006) CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J. Clin. Invest. 116, 115-124.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 115-124
-
-
Weisberg, S.P.1
Hunter, D.2
Huber, R.3
Lemieux, J.4
Slaymaker, S.5
Vaddi, K.6
Charo, I.7
Leibel, R.L.8
Ferrante Jr., A.W.9
-
16
-
-
33745216724
-
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
-
Kanda, H., Tateya, S., Tamori, Y., Kotani, K., Hiasa, K., Kitazawa, R., Kitazawa, S., Miyachi, H., Maeda, S., Egashira, K., Kasuga, M. (2006) MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J. Clin. Invest. 116, 1494-1505.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1494-1505
-
-
Kanda, H.1
Tateya, S.2
Tamori, Y.3
Kotani, K.4
Hiasa, K.5
Kitazawa, R.6
Kitazawa, S.7
Miyachi, H.8
Maeda, S.9
Egashira, K.10
Kasuga, M.11
-
17
-
-
33748750917
-
Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance
-
Kamei, N., Tobe, K., Suzuki, R., Ohsugi, M., Watanabe, T., Kubota, N., Ohtsuka-Kowatari, N., Kumagai, K., Sakamoto, K., Kobayashi, M., Yamauchi, T., Ueki, K., Oishi, Y., Nishimura, S., Manabe, I., Hashimoto, H., Ohnishi, Y., Ogata, H., Tokuyama, K., Tsunoda, M., Ide, T., Murakami, K., Nagai, R., Kadowaki, T. (2006) Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance. J. Biol. Chem. 281, 26602-26614.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 26602-26614
-
-
Kamei, N.1
Tobe, K.2
Suzuki, R.3
Ohsugi, M.4
Watanabe, T.5
Kubota, N.6
Ohtsuka-Kowatari, N.7
Kumagai, K.8
Sakamoto, K.9
Kobayashi, M.10
Yamauchi, T.11
Ueki, K.12
Oishi, Y.13
Nishimura, S.14
Manabe, I.15
Hashimoto, H.16
Ohnishi, Y.17
Ogata, H.18
Tokuyama, K.19
Tsunoda, M.20
Ide, T.21
Murakami, K.22
Nagai, R.23
Kadowaki, T.24
more..
-
18
-
-
58149102605
-
Role of CC chemokine receptor 2 in bone marrow cells in the recruitment of macrophages into obese adipose tissue
-
Ito, A., Suganami, T., Yamauchi, A., Degawa-Yamauchi, M., Tanaka, M., Kouyama, R., Kobayashi, Y., Nitta, N., Yasuda, K., Hirata, Y., Kuziel, W. A., Takeya, M., Kanegasaki, S., Kamei, Y., Ogawa, Y. (2008) Role of CC chemokine receptor 2 in bone marrow cells in the recruitment of macrophages into obese adipose tissue. J. Biol. Chem. 283, 35715-35723.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 35715-35723
-
-
Ito, A.1
Suganami, T.2
Yamauchi, A.3
Degawa-Yamauchi, M.4
Tanaka, M.5
Kouyama, R.6
Kobayashi, Y.7
Nitta, N.8
Yasuda, K.9
Hirata, Y.10
Kuziel, W.A.11
Takeya, M.12
Kanegasaki, S.13
Kamei, Y.14
Ogawa, Y.15
-
19
-
-
34948813665
-
Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice
-
Nomiyama, T., Perez-Tilve, D., Ogawa, D., Gizard, F., Zhao, Y., Heywood, E. B., Jones, K. L., Kawamori, R., Cassis, L. A., Tschop, M. H., Bruemmer, D. (2007) Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice. J. Clin. Invest. 117, 2877-2888.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2877-2888
-
-
Nomiyama, T.1
Perez-Tilve, D.2
Ogawa, D.3
Gizard, F.4
Zhao, Y.5
Heywood, E.B.6
Jones, K.L.7
Kawamori, R.8
Cassis, L.A.9
Tschop, M.H.10
Bruemmer, D.11
-
20
-
-
35648947853
-
Disruption of CXC motif chemokine ligand-14 in mice ameliorates obesity-induced insulin resistance
-
Nara, N., Nakayama, Y., Okamoto, S., Tamura, H., Kiyono, M., Muraoka, M., Tanaka, K., Taya, C., Shitara, H., Ishii, R., Yonekawa, H., Minokoshi, Y., Hara, T. (2007) Disruption of CXC motif chemokine ligand-14 in mice ameliorates obesity-induced insulin resistance. J. Biol. Chem. 282, 30794-30803.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 30794-30803
-
-
Nara, N.1
Nakayama, Y.2
Okamoto, S.3
Tamura, H.4
Kiyono, M.5
Muraoka, M.6
Tanaka, K.7
Taya, C.8
Shitara, H.9
Ishii, R.10
Yonekawa, H.11
Minokoshi, Y.12
Hara, T.13
-
21
-
-
69149090011
-
Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance
-
Tabata, M., Kadomatsu, T., Fukuhara, S., Miyata, K., Ito, Y., Endo, M., Urano, T., Zhu, H. J., Tsukano, H., Tazume, H., Kaikita, K., Miyashita, K., Iwawaki, T., Shimabukuro, M., Sakaguchi, K., Ito, T., Nakagata, N., Yamada, T., Katagiri, H., Kasuga, M., Ando, Y., Ogawa, H., Mochizuki, N., Itoh, H., Suda, T., Oike, Y. (2009) Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance. Cell Metab. 10, 178-188.
-
(2009)
Cell Metab.
, vol.10
, pp. 178-188
-
-
Tabata, M.1
Kadomatsu, T.2
Fukuhara, S.3
Miyata, K.4
Ito, Y.5
Endo, M.6
Urano, T.7
Zhu, H.J.8
Tsukano, H.9
Tazume, H.10
Kaikita, K.11
Miyashita, K.12
Iwawaki, T.13
Shimabukuro, M.14
Sakaguchi, K.15
Ito, T.16
Nakagata, N.17
Yamada, T.18
Katagiri, H.19
Kasuga, M.20
Ando, Y.21
Ogawa, H.22
Mochizuki, N.23
Itoh, H.24
Suda, T.25
Oike, Y.26
more..
-
22
-
-
0037032817
-
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
-
Johnson, G. L., Lapadat, R. (2002) Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298, 1911-1912.
-
(2002)
Science
, vol.298
, pp. 1911-1912
-
-
Johnson, G.L.1
Lapadat, R.2
-
23
-
-
14544298335
-
The role of MAPKs in adipocyte differentiation and obesity
-
Bost, F., Aouadi, M., Caron, L., Binetruy, B. (2005) The role of MAPKs in adipocyte differentiation and obesity. Biochimie 87, 51-56.
-
(2005)
Biochimie
, vol.87
, pp. 51-56
-
-
Bost, F.1
Aouadi, M.2
Caron, L.3
Binetruy, B.4
-
24
-
-
0037153158
-
A central role for JNK in obesity and insulin resistance
-
Hirosumi, J., Tuncman, G., Chang, L., Gorgun, C. Z., Uysal, K. T., Maeda, K., Karin, M., Hotamisligil, G. S. (2002) A central role for JNK in obesity and insulin resistance. Nature 420, 333-336.
-
(2002)
Nature
, vol.420
, pp. 333-336
-
-
Hirosumi, J.1
Tuncman, G.2
Chang, L.3
Gorgun, C.Z.4
Uysal, K.T.5
Maeda, K.6
Karin, M.7
Hotamisligil, G.S.8
-
25
-
-
2042538029
-
Structure and regulation of MAPK phosphatases
-
Farooq, A., Zhou, M. M. (2004) Structure and regulation of MAPK phosphatases. Cell. Signal. 16, 769-779.
-
(2004)
Cell. Signal.
, vol.16
, pp. 769-779
-
-
Farooq, A.1
Zhou, M.M.2
-
26
-
-
0034096201
-
Protein phosphatases and the regulation of mitogen-activated protein kinase signaling
-
Keyse, S. M. (2000) Protein phosphatases and the regulation of mitogen-activated protein kinase signaling. Curr. Opin. Cell Biol. 12, 186-192.
-
(2000)
Curr. Opin. Cell Biol.
, vol.12
, pp. 186-192
-
-
Keyse, S.M.1
-
27
-
-
34548541264
-
Role of MAPK phosphatase-1 in the induction of monocyte chemoattractant protein-1 during the course of adipocyte hypertrophy
-
Ito, A., Suganami, T., Miyamoto, Y., Yoshimasa, Y., Takeya, M., Kamei, Y., Ogawa, Y. (2007) Role of MAPK phosphatase-1 in the induction of monocyte chemoattractant protein-1 during the course of adipocyte hypertrophy. J. Biol. Chem. 282, 25445-25452.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 25445-25452
-
-
Ito, A.1
Suganami, T.2
Miyamoto, Y.3
Yoshimasa, Y.4
Takeya, M.5
Kamei, Y.6
Ogawa, Y.7
-
28
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan, U., Cao, Q., Yilmaz, E., Lee, A. H., Iwakoshi, N. N., Ozdelen, E., Tuncman, G., Gorgun, C., Glimcher, L. H., Hotamisligil, G. S. (2004) Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306, 457-461.
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Ozdelen, E.6
Tuncman, G.7
Gorgun, C.8
Glimcher, L.H.9
Hotamisligil, G.S.10
-
29
-
-
34047119110
-
Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation
-
Hosogai, N., Fukuhara, A., Oshima, K., Miyata, Y., Tanaka, S., Segawa, K., Furukawa, S., Tochino, Y., Komuro, R., Matsuda, M., Shimomura, I. (2007) Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation. Diabetes 56, 901-911.
-
(2007)
Diabetes
, vol.56
, pp. 901-911
-
-
Hosogai, N.1
Fukuhara, A.2
Oshima, K.3
Miyata, Y.4
Tanaka, S.5
Segawa, K.6
Furukawa, S.7
Tochino, Y.8
Komuro, R.9
Matsuda, M.10
Shimomura, I.11
-
30
-
-
85030434746
-
Increased oxidative stress in obesity and its impact on metabolic syndrome
-
Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., Shimomura, I. (2004) Increased oxidative stress in obesity and its impact on metabolic syndrome. J. Clin. Invest. 114, 1752-1761.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1752-1761
-
-
Furukawa, S.1
Fujita, T.2
Shimabukuro, M.3
Iwaki, M.4
Yamada, Y.5
Nakajima, Y.6
Nakayama, O.7
Makishima, M.8
Matsuda, M.9
Shimomura, I.10
-
31
-
-
26244448904
-
A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: Role of free fatty acids and tumor necrosis factor α
-
Suganami, T., Nishida, J., Ogawa, Y. (2005) A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor α. Arterioscler. Thromb. Vasc. Biol. 25, 2062-2068.
-
(2005)
Arterioscler. Thromb. Vasc. Biol.
, vol.25
, pp. 2062-2068
-
-
Suganami, T.1
Nishida, J.2
Ogawa, Y.3
-
32
-
-
33846323706
-
Role of the Toll-like receptor 4/NF-κB pathway in saturated fatty acid-induced inflammatory changes in the interaction between adipocytes and macrophages
-
Suganami, T., Tanimoto-Koyama, K., Nishida, J., Itoh, M., Yuan, X., Mizuarai, S., Kotani, H., Yamaoka, S., Miyake, K., Aoe, S., Kamei, Y., Ogawa, Y. (2007) Role of the Toll-like receptor 4/NF-κB pathway in saturated fatty acid-induced inflammatory changes in the interaction between adipocytes and macrophages. Arterioscler. Thromb. Vasc. Biol. 27, 84-91.
-
(2007)
Arterioscler. Thromb. Vasc. Biol.
, vol.27
, pp. 84-91
-
-
Suganami, T.1
Tanimoto-Koyama, K.2
Nishida, J.3
Itoh, M.4
Yuan, X.5
Mizuarai, S.6
Kotani, H.7
Yamaoka, S.8
Miyake, K.9
Aoe, S.10
Kamei, Y.11
Ogawa, Y.12
-
33
-
-
0035907302
-
Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
-
Lee, J. Y., Sohn, K. H., Rhee, S. H., Hwang, D. (2001) Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. J. Biol. Chem. 276, 16683-16689.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16683-16689
-
-
Lee, J.Y.1
Sohn, K.H.2
Rhee, S.H.3
Hwang, D.4
-
34
-
-
33846302361
-
Attenuation of obesity-induced adipose tissue inflammation in C3H/HeJ mice carrying a Toll-like receptor 4 mutation
-
DOI 10.1016/j.bbrc.2006.12.190, PII S0006291X06027793
-
Suganami, T., Mieda, T., Itoh, M., Shimoda, Y., Kamei, Y., Ogawa, Y. (2007) Attenuation of obesity-induced adipose tissue inflammation in C3H/HeJ mice carrying a Toll-like receptor 4 mutation. Biochem. Biophys. Res. Commun. 354, 45-49. (Pubitemid 46123196)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.354
, Issue.1
, pp. 45-49
-
-
Suganami, T.1
Mieda, T.2
Itoh, M.3
Shimoda, Y.4
Kamei, Y.5
Ogawa, Y.6
-
35
-
-
0036083377
-
Lipopolysaccharide stimulation of ERK1/2 increases TNF-α production via Egr-1
-
Shi, L., Kishore, R., McMullen, M. R., Nagy, L. E. (2002) Lipopolysaccharide stimulation of ERK1/2 increases TNF-α production via Egr-1. Am. J. Physiol. Cell Physiol. 282, C1205-C1211.
-
(2002)
Am. J. Physiol. Cell Physiol.
, vol.282
-
-
Shi, L.1
Kishore, R.2
McMullen, M.R.3
Nagy, L.E.4
-
36
-
-
34247884376
-
C3H/HeJ mice carrying a Toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet
-
Poggi, M., Bastelica, D., Gual, P., Iglesias, M. A., Gremeaux, T., Knauf, C., Peiretti, F., Verdier, M., Juhan-Vague, I., Tanti, J. F., Burcelin, R., Alessi, M. C. (2007) C3H/HeJ mice carrying a Toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet. Diabetologia 50, 1267-1276.
-
(2007)
Diabetologia
, vol.50
, pp. 1267-1276
-
-
Poggi, M.1
Bastelica, D.2
Gual, P.3
Iglesias, M.A.4
Gremeaux, T.5
Knauf, C.6
Peiretti, F.7
Verdier, M.8
Juhan-Vague, I.9
Tanti, J.F.10
Burcelin, R.11
Alessi, M.C.12
-
37
-
-
34547602916
-
Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance
-
Tsukumo, D. M., Carvalho-Filho, M. A., Carvalheira, J. B., Prada, P. O., Hirabara, S. M., Schenka, A. A., Araujo, E. P., Vassallo, J., Curi, R., Velloso, L. A., Saad, M. J. (2007) Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance. Diabetes 56, 1986-1998.
-
(2007)
Diabetes
, vol.56
, pp. 1986-1998
-
-
Tsukumo, D.M.1
Carvalho-Filho, M.A.2
Carvalheira, J.B.3
Prada, P.O.4
Hirabara, S.M.5
Schenka, A.A.6
Araujo, E.P.7
Vassallo, J.8
Curi, R.9
Velloso, L.A.10
Saad, M.J.11
-
38
-
-
70350389389
-
Hematopoietic cell-specific deletion of Toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice
-
Saberi, M., Woods, N. B., de Luca, C., Schenk, S., Lu, J. C., Bandyopadhyay, G., Verma, I. M., Olefsky, J. M. (2009) Hematopoietic cell-specific deletion of Toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice. Cell Metab. 10, 419-429.
-
(2009)
Cell Metab.
, vol.10
, pp. 419-429
-
-
Saberi, M.1
Woods, N.B.2
De Luca, C.3
Schenk, S.4
Lu, J.C.5
Bandyopadhyay, G.6
Verma, I.M.7
Olefsky, J.M.8
-
39
-
-
0038143617
-
Differential modulation of Toll-like receptors by fatty acids: Preferential inhibition by n-3 polyunsaturated fatty acids
-
DOI 10.1194/jlr.M200361-JLR200
-
Lee, J. Y., Plakidas, A., Lee, W. H., Heikkinen, A., Chanmugam, P., Bray, G., Hwang, D. H. (2003) Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids. J. Lipid Res. 44, 479-486. (Pubitemid 37279695)
-
(2003)
Journal of Lipid Research
, vol.44
, Issue.3
, pp. 479-486
-
-
Lee, J.Y.1
Plakidas, A.2
Lee, W.H.3
Heikkinen, A.4
Chanmugam, P.5
Bray, G.6
Hwang, D.H.7
-
40
-
-
34548274430
-
Increased adiponectin secretion by highly purified eicosapentaenoic acid in rodent models of obesity and human obese subjects
-
Itoh, M., Suganami, T., Satoh, N., Tanimoto-Koyama, K., Yuan, X., Tanaka, M., Kawano, H., Yano, T., Aoe, S., Takeya, M., Shimatsu, A., Kuzuya, H., Kamei, Y., Ogawa, Y. (2007) Increased adiponectin secretion by highly purified eicosapentaenoic acid in rodent models of obesity and human obese subjects. Arterioscler. Thromb. Vasc. Biol. 27, 1918-1925.
-
(2007)
Arterioscler. Thromb. Vasc. Biol.
, vol.27
, pp. 1918-1925
-
-
Itoh, M.1
Suganami, T.2
Satoh, N.3
Tanimoto-Koyama, K.4
Yuan, X.5
Tanaka, M.6
Kawano, H.7
Yano, T.8
Aoe, S.9
Takeya, M.10
Shimatsu, A.11
Kuzuya, H.12
Kamei, Y.13
Ogawa, Y.14
-
41
-
-
0030756346
-
Protection from obesity-induced insulin resistance in mice lacking TNF-α function
-
Uysal, K. T., Wiesbrock, S. M., Marino, M. W., Hotamisligil, G. S. (1997) Protection from obesity-induced insulin resistance in mice lacking TNF-α function. Nature 389, 610-614.
-
(1997)
Nature
, vol.389
, pp. 610-614
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Marino, M.W.3
Hotamisligil, G.S.4
-
42
-
-
17944365228
-
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
-
Yamauchi, T., Kamon, J., Waki, H., Terauchi, Y., Kubota, N., Hara, K., Mori, Y., Ide, T., Murakami, K., Tsuboyama-Kasaoka, N., Ezaki, O., Akanuma, Y., Gavrilova, O., Vinson, C., Reitman, M. L., Kagechika, H., Shudo, K., Yoda, M., Nakano, Y., Tobe, K., Nagai, R., Kimura, S., Tomita, M., Froguel, P., Kadowaki, T. (2001) The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat. Med. 7, 941-946.
-
(2001)
Nat. Med.
, vol.7
, pp. 941-946
-
-
Yamauchi, T.1
Kamon, J.2
Waki, H.3
Terauchi, Y.4
Kubota, N.5
Hara, K.6
Mori, Y.7
Ide, T.8
Murakami, K.9
Tsuboyama-Kasaoka, N.10
Ezaki, O.11
Akanuma, Y.12
Gavrilova, O.13
Vinson, C.14
Reitman, M.L.15
Kagechika, H.16
Shudo, K.17
Yoda, M.18
Nakano, Y.19
Tobe, K.20
Nagai, R.21
Kimura, S.22
Tomita, M.23
Froguel, P.24
Kadowaki, T.25
more..
-
43
-
-
0036063777
-
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30
-
Maeda, N., Shimomura, I., Kishida, K., Nishizawa, H., Matsuda, M., Nagaretani, H., Furuyama, N., Kondo, H., Takahashi, M., Arita, Y., Komuro, R., Ouchi, N., Kihara, S., Tochino, Y., Okutomi, K., Horie, M., Takeda, S., Aoyama, T., Funahashi, T., Matsuzawa, Y. (2002) Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nat. Med. 8, 731-737.
-
(2002)
Nat. Med.
, vol.8
, pp. 731-737
-
-
Maeda, N.1
Shimomura, I.2
Kishida, K.3
Nishizawa, H.4
Matsuda, M.5
Nagaretani, H.6
Furuyama, N.7
Kondo, H.8
Takahashi, M.9
Arita, Y.10
Komuro, R.11
Ouchi, N.12
Kihara, S.13
Tochino, Y.14
Okutomi, K.15
Horie, M.16
Takeda, S.17
Aoyama, T.18
Funahashi, T.19
Matsuzawa, Y.20
more..
-
44
-
-
77149154977
-
An increase in the circulating concentration of monocyte chemoattractant protein-1 elicits systemic insulin resistance irrespective of adipose tissue inflammation in mice
-
Tateya, S., Tamori, Y., Kawaguchi, T., Kanda, H., Kasuga, M. (2010) An increase in the circulating concentration of monocyte chemoattractant protein-1 elicits systemic insulin resistance irrespective of adipose tissue inflammation in mice. Endocrinology 151, 971-979.
-
(2010)
Endocrinology
, vol.151
, pp. 971-979
-
-
Tateya, S.1
Tamori, Y.2
Kawaguchi, T.3
Kanda, H.4
Kasuga, M.5
-
45
-
-
0032848779
-
Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin
-
Ogawa, Y., Masuzaki, H., Hosoda, K., Aizawa-Abe, M., Suga, J., Suda, M., Ebihara, K., Iwai, H., Matsuoka, N., Satoh, N., Odaka, H., Kasuga, H., Fujisawa, Y., Inoue, G., Nishimura, H., Yoshimasa, Y., Nakao, K. (1999) Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin. Diabetes 48, 1822-1829.
-
(1999)
Diabetes
, vol.48
, pp. 1822-1829
-
-
Ogawa, Y.1
Masuzaki, H.2
Hosoda, K.3
Aizawa-Abe, M.4
Suga, J.5
Suda, M.6
Ebihara, K.7
Iwai, H.8
Matsuoka, N.9
Satoh, N.10
Odaka, H.11
Kasuga, H.12
Fujisawa, Y.13
Inoue, G.14
Nishimura, H.15
Yoshimasa, Y.16
Nakao, K.17
-
46
-
-
0032558725
-
Leptin and the regulation of body weight in mammals
-
DOI 10.1038/27376
-
Friedman, J. M., Halaas, J. L. (1998) Leptin and the regulation of body weight in mammals. Nature 395, 763-770. (Pubitemid 28485436)
-
(1998)
Nature
, vol.395
, Issue.6704
, pp. 763-770
-
-
Friedman, J.M.1
Halaas, J.L.2
-
47
-
-
76049099485
-
Role of central leptin signaling in renal macrophage infiltration
-
Tanaka, M., Suganami, T., Sugita, S., Shimoda, Y., Kasahara, M., Aoe, S., Takeya, M., Takeda, S., Kamei, Y., Ogawa, Y. (2010) Role of central leptin signaling in renal macrophage infiltration. Endocr. J. 57, 61-72.
-
(2010)
Endocr. J.
, vol.57
, pp. 61-72
-
-
Tanaka, M.1
Suganami, T.2
Sugita, S.3
Shimoda, Y.4
Kasahara, M.5
Aoe, S.6
Takeya, M.7
Takeda, S.8
Kamei, Y.9
Ogawa, Y.10
-
48
-
-
0347823193
-
Leptin Promotes Vascular Remodeling and Neointimal Growth in Mice
-
DOI 10.1161/01.ATV.0000105904.02142.e7
-
Schafer, K., Halle, M., Goeschen, C., Dellas, C., Pynn, M., Loskutoff, D. J., Konstantinides, S. (2004) Leptin promotes vascular remodeling and neointimal growth in mice. Arterioscler. Thromb. Vasc. Biol. 24, 112-117. (Pubitemid 38082420)
-
(2004)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.24
, Issue.1
, pp. 112-117
-
-
Schafer, K.1
Halle, M.2
Goeschen, C.3
Dellas, C.4
Pynn, M.5
Loskutoff, D.J.6
Konstantinides, S.7
-
49
-
-
0242721942
-
Neointimal Formation after Endovascular Arterial Injury Is Markedly Attenuated in db/db Mice
-
DOI 10.1161/01.ATV.0000096394.32433.E9
-
Stephenson, K., Tunstead, J., Tsai, A., Gordon, R., Henderson, S., Dansky, H. M. (2003) Neointimal formation after endovascular arterial injury is markedly attenuated in db/db mice. Arterioscler. Thromb. Vasc. Biol. 23, 2027-2033. (Pubitemid 37433196)
-
(2003)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.23
, Issue.11
, pp. 2027-2033
-
-
Stephenson, K.1
Tunstead, J.2
Tsai, A.3
Gordon, R.4
Henderson, S.5
Dansky, H.M.6
-
50
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
Lumeng, C. N., Bodzin, J. L., Saltiel, A. R. (2007) Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J. Clin. Invest. 117, 175-184.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
51
-
-
58149347227
-
Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes
-
Lumeng, C. N., DelProposto, J. B., Westcott, D. J., Saltiel, A. R. (2008) Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes. Diabetes 57, 3239-3246.
-
(2008)
Diabetes
, vol.57
, pp. 3239-3246
-
-
Lumeng, C.N.1
DelProposto, J.B.2
Westcott, D.J.3
Saltiel, A.R.4
-
52
-
-
44349161098
-
Alternative M2 Activation of Kupffer Cells by PPARδ Ameliorates Obesity-Induced Insulin Resistance
-
DOI 10.1016/j.cmet.2008.04.003, PII S1550413108001137
-
Odegaard, J. I., Ricardo-Gonzalez, R. R., Red Eagle, A., Vats, D., Morel, C. R., Goforth, M. H., Subramanian, V., Mukundan, L., Ferrante, A. W., Chawla, A. (2008) Alternative M2 activation of Kupffer cells by PPARδ ameliorates obesity-induced insulin resistance. Cell Metab. 7, 496-507. (Pubitemid 351729205)
-
(2008)
Cell Metabolism
, vol.7
, Issue.6
, pp. 496-507
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Red Eagle, A.3
Vats, D.4
Morel, C.R.5
Goforth, M.H.6
Subramanian, V.7
Mukundan, L.8
Ferrante, A.W.9
Chawla, A.10
-
53
-
-
34347354309
-
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
-
Odegaard, J. I., Ricardo-Gonzalez, R. R., Goforth, M. H., Morel, C. R., Subramanian, V., Mukundan, L., Red Eagle, A., Vats, D., Brombacher, F., Ferrante, A. W., Chawla, A. (2007) Macrophage-specific PPARγ controls alternative activation and improves insulin resistance. Nature 447, 1116-1120.
-
(2007)
Nature
, vol.447
, pp. 1116-1120
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Goforth, M.H.3
Morel, C.R.4
Subramanian, V.5
Mukundan, L.6
Red Eagle, A.7
Vats, D.8
Brombacher, F.9
Ferrante, A.W.10
Chawla, A.11
-
54
-
-
44349112305
-
Adipocyte-Derived Th2 Cytokines and Myeloid PPARδ Regulate Macrophage Polarization and Insulin Sensitivity
-
DOI 10.1016/j.cmet.2008.04.002, PII S1550413108001125
-
Kang, K., Reilly, S. M., Karabacak, V., Gangl, M. R., Fitzgerald, K., Hatano, B., Lee, C. H. (2008) Adipocyte-derived Th2 cytokines and myeloid PPARδ regulate macrophage polarization and insulin sensitivity. Cell Metab. 7, 485-495. (Pubitemid 351729204)
-
(2008)
Cell Metabolism
, vol.7
, Issue.6
, pp. 485-495
-
-
Kang, K.1
Reilly, S.M.2
Karabacak, V.3
Gangl, M.R.4
Fitzgerald, K.5
Hatano, B.6
Lee, C.-H.7
-
55
-
-
67949091182
-
Activating transcription factor 3 constitutes a negative feedback mechanism that attenuates saturated fatty acid/Toll-like receptor 4 signaling and macrophage activation in obese adipose tissue
-
Suganami, T., Yuan, X., Shimoda, Y., Uchio-Yamada, K., Nakagawa, N., Shirakawa, I., Usami, T., Tsukahara, T., Nakayama, K., Miyamoto, Y., Yasuda, K., Matsuda, J., Kamei, Y., Kitajima, S., Ogawa, Y. (2009) Activating transcription factor 3 constitutes a negative feedback mechanism that attenuates saturated fatty acid/Toll-like receptor 4 signaling and macrophage activation in obese adipose tissue. Circ. Res. 105, 25-32.
-
(2009)
Circ. Res.
, vol.105
, pp. 25-32
-
-
Suganami, T.1
Yuan, X.2
Shimoda, Y.3
Uchio-Yamada, K.4
Nakagawa, N.5
Shirakawa, I.6
Usami, T.7
Tsukahara, T.8
Nakayama, K.9
Miyamoto, Y.10
Yasuda, K.11
Matsuda, J.12
Kamei, Y.13
Kitajima, S.14
Ogawa, Y.15
-
56
-
-
74249084928
-
Unbalanced M1/M2 phenotype of peripheral blood monocytes in obese diabetic patients: Effect of pioglitazone
-
Satoh, N., Shimatsu, A., Himeno, A., Sasaki, Y., Yamakage, H., Yamada, K., Suganami, T., Ogawa, Y. (2010) Unbalanced M1/M2 phenotype of peripheral blood monocytes in obese diabetic patients: effect of pioglitazone. Diabetes Care 33, e7.
-
(2010)
Diabetes Care
, vol.33
-
-
Satoh, N.1
Shimatsu, A.2
Himeno, A.3
Sasaki, Y.4
Yamakage, H.5
Yamada, K.6
Suganami, T.7
Ogawa, Y.8
-
57
-
-
34547492488
-
PPARγ activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties
-
Bouhlel, M. A., Derudas, B., Rigamonti, E., Dievart, R., Brozek, J., Haulon, S., Zawadzki, C., Jude, B., Torpier, G., Marx, N., Staels, B., Chinetti-Gbaguidi, G. (2007) PPARγ activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties. Cell Metab. 6, 137-143.
-
(2007)
Cell Metab.
, vol.6
, pp. 137-143
-
-
Bouhlel, M.A.1
Derudas, B.2
Rigamonti, E.3
Dievart, R.4
Brozek, J.5
Haulon, S.6
Zawadzki, C.7
Jude, B.8
Torpier, G.9
Marx, N.10
Staels, B.11
Chinetti-Gbaguidi, G.12
-
58
-
-
33745428666
-
Oxidative metabolism and PGC-1 attenuate macrophage-mediated inflammation
-
DOI 10.1016/j.cmet.2006.05.011, PII S1550413106002026
-
Vats, D., Mukundan, L., Odegaard, J. I., Zhang, L., Smith, K. L., Morel, C. R., Wagner, R. A., Greaves, D. R., Murray, P. J., Chawla, A. (2006) Oxidative metabolism and PGC-1 attenuate macrophage-mediated inflammation. Cell Metab. 4, 13-24. (Pubitemid 43942258)
-
(2006)
Cell Metabolism
, vol.4
, Issue.1
, pp. 13-24
-
-
Vats, D.1
Mukundan, L.2
Odegaard, J.I.3
Zhang, L.4
Smith, K.L.5
Morel, C.R.6
Greaves, D.R.7
Murray, P.J.8
Chawla, A.9
-
59
-
-
70350560546
-
Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice
-
Fujisaka, S., Usui, I., Bukhari, A., Ikutani, M., Oya, T., Kanatani, Y., Tsuneyama, K., Nagai, Y., Takatsu, K., Urakaze, M., Kobayashi, M., Tobe, K. (2009) Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice. Diabetes 58, 2574-2582.
-
(2009)
Diabetes
, vol.58
, pp. 2574-2582
-
-
Fujisaka, S.1
Usui, I.2
Bukhari, A.3
Ikutani, M.4
Oya, T.5
Kanatani, Y.6
Tsuneyama, K.7
Nagai, Y.8
Takatsu, K.9
Urakaze, M.10
Kobayashi, M.11
Tobe, K.12
-
60
-
-
34249907880
-
Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
-
Hevener, A. L., Olefsky, J. M., Reichart, D., Nguyen, M. T., Bandyopadyhay, G., Leung, H. Y., Watt, M. J., Benner, C., Febbraio, M. A., Nguyen, A. K., Folian, B., Subramaniam, S., Gonzalez, F. J., Glass, C. K., Ricote, M. (2007) Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. J. Clin. Invest. 117, 1658-1669.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1658-1669
-
-
Hevener, A.L.1
Olefsky, J.M.2
Reichart, D.3
Nguyen, M.T.4
Bandyopadyhay, G.5
Leung, H.Y.6
Watt, M.J.7
Benner, C.8
Febbraio, M.A.9
Nguyen, A.K.10
Folian, B.11
Subramaniam, S.12
Gonzalez, F.J.13
Glass, C.K.14
Ricote, M.15
-
61
-
-
75149169811
-
Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice
-
Ohmura, K., Ishimori, N., Ohmura, Y., Tokuhara, S., Nozawa, A., Horii, S., Andoh, Y., Fujii, S., Iwabuchi, K., Onoe, K., Tsutsui, H. (2010) Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice. Arterioscler. Thromb. Vasc. Biol. 30, 193-199.
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 193-199
-
-
Ohmura, K.1
Ishimori, N.2
Ohmura, Y.3
Tokuhara, S.4
Nozawa, A.5
Horii, S.6
Andoh, Y.7
Fujii, S.8
Iwabuchi, K.9
Onoe, K.10
Tsutsui, H.11
-
62
-
-
53149119231
-
Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding
-
Elgazar-Carmon, V., Rudich, A., Hadad, N., Levy, R. (2008) Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding. J. Lipid Res. 49, 1894-1903.
-
(2008)
J. Lipid Res.
, vol.49
, pp. 1894-1903
-
-
Elgazar-Carmon, V.1
Rudich, A.2
Hadad, N.3
Levy, R.4
-
63
-
-
68349150756
-
+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
-
+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat. Med. 15, 914-920.
-
(2009)
Nat. Med.
, vol.15
, pp. 914-920
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
Eto, K.4
Yamashita, H.5
Ohsugi, M.6
Otsu, M.7
Hara, K.8
Ueki, K.9
Sugiura, S.10
Yoshimura, K.11
Kadowaki, T.12
Nagai, R.13
-
64
-
-
68349137821
-
Normalization of obesity-associated insulin resistance through immunotherapy
-
Winer, S., Chan, Y., Paltser, G., Truong, D., Tsui, H., Bahrami, J., Dorfman, R., Wang, Y., Zielenski, J., Mastronardi, F., Maezawa, Y., Drucker, D. J., Engleman, E., Winer, D., Dosch, H. M. (2009) Normalization of obesity-associated insulin resistance through immunotherapy. Nat. Med. 15, 921-929.
-
(2009)
Nat. Med.
, vol.15
, pp. 921-929
-
-
Winer, S.1
Chan, Y.2
Paltser, G.3
Truong, D.4
Tsui, H.5
Bahrami, J.6
Dorfman, R.7
Wang, Y.8
Zielenski, J.9
Mastronardi, F.10
Maezawa, Y.11
Drucker, D.J.12
Engleman, E.13
Winer, D.14
Dosch, H.M.15
-
65
-
-
68349148211
-
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
-
Feuerer, M., Herrero, L., Cipolletta, D., Naaz, A., Wong, J., Nayer, A., Lee, J., Goldfine, A. B., Benoist, C., Shoelson, S., Mathis, D. (2009) Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat. Med. 15, 930-939.
-
(2009)
Nat. Med.
, vol.15
, pp. 930-939
-
-
Feuerer, M.1
Herrero, L.2
Cipolletta, D.3
Naaz, A.4
Wong, J.5
Nayer, A.6
Lee, J.7
Goldfine, A.B.8
Benoist, C.9
Shoelson, S.10
Mathis, D.11
-
66
-
-
46249117032
-
T-lymphocyte infiltration in visceral adipose tissue: A primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance
-
Kintscher, U., Hartge, M., Hess, K., Foryst-Ludwig, A., Clemenz, M., Wabitsch, M., Fischer-Posovszky, P., Barth, T. F., Dragun, D., Skurk, T., Hauner, H., Bluher, M., Unger, T., Wolf, A. M., Knippschild, U., Hombach, V., Marx, N. (2008) T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance. Arterioscler. Thromb. Vasc. Biol. 28, 1304-1310.
-
(2008)
Arterioscler. Thromb. Vasc. Biol.
, vol.28
, pp. 1304-1310
-
-
Kintscher, U.1
Hartge, M.2
Hess, K.3
Foryst-Ludwig, A.4
Clemenz, M.5
Wabitsch, M.6
Fischer-Posovszky, P.7
Barth, T.F.8
Dragun, D.9
Skurk, T.10
Hauner, H.11
Bluher, M.12
Unger, T.13
Wolf, A.M.14
Knippschild, U.15
Hombach, V.16
Marx, N.17
-
67
-
-
75749122181
-
+ lymphoid cells
-
+ lymphoid cells. Nature 463, 540-544.
-
(2010)
Nature
, vol.463
, pp. 540-544
-
-
Moro, K.1
Yamada, T.2
Tanabe, M.3
Takeuchi, T.4
Ikawa, T.5
Kawamoto, H.6
Furusawa, J.7
Ohtani, M.8
Fujii, H.9
Koyasu, S.10
-
68
-
-
0037066502
-
Decoding the patterns of self and nonself by the innate immune system
-
Medzhitov, R., Janeway Jr., C. A. (2002) Decoding the patterns of self and nonself by the innate immune system. Science 296, 298-300.
-
(2002)
Science
, vol.296
, pp. 298-300
-
-
Medzhitov, R.1
Janeway Jr., C.A.2
-
69
-
-
38549136572
-
Macrophage activation by endogenous danger signals
-
Zhang, X., Mosser, D. M. (2008) Macrophage activation by endogenous danger signals. J. Pathol. 214, 161-178.
-
(2008)
J. Pathol.
, vol.214
, pp. 161-178
-
-
Zhang, X.1
Mosser, D.M.2
-
70
-
-
27444437321
-
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
-
Cinti, S., Mitchell, G., Barbatelli, G., Murano, I., Ceresi, E., Faloia, E., Wang, S., Fortier, M., Greenberg, A. S., Obin, M. S. (2005) Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J. Lipid Res. 46, 2347-2355.
-
(2005)
J. Lipid Res.
, vol.46
, pp. 2347-2355
-
-
Cinti, S.1
Mitchell, G.2
Barbatelli, G.3
Murano, I.4
Ceresi, E.5
Faloia, E.6
Wang, S.7
Fortier, M.8
Greenberg, A.S.9
Obin, M.S.10
-
71
-
-
77449083262
-
Adipocyte apoptosis, a link between obesity, insulin resistance, and hepatic steatosis
-
Alkhouri, N., Gornicka, A., Berk, M. P., Thapaliya, S., Dixon, L. J., Kashyap, S., Schauer, P. R., Feldstein, A. E. (2010) Adipocyte apoptosis, a link between obesity, insulin resistance, and hepatic steatosis. J. Biol. Chem. 285, 3428-3438.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 3428-3438
-
-
Alkhouri, N.1
Gornicka, A.2
Berk, M.P.3
Thapaliya, S.4
Dixon, L.J.5
Kashyap, S.6
Schauer, P.R.7
Feldstein, A.E.8
-
72
-
-
74949138985
-
Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice
-
Wueest, S., Rapold, R. A., Schumann, D. M., Rytka, J. M., Schildknecht, A., Nov, O., Chervonsky, A. V., Rudich, A., Schoenle, E. J., Donath, M. Y., Konrad, D. (2010) Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice. J. Clin. Invest. 120, 191-202.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 191-202
-
-
Wueest, S.1
Rapold, R.A.2
Schumann, D.M.3
Rytka, J.M.4
Schildknecht, A.5
Nov, O.6
Chervonsky, A.V.7
Rudich, A.8
Schoenle, E.J.9
Donath, M.Y.10
Konrad, D.11
|