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Volumn 50, Issue 9, 2004, Pages 1511-1525

Endocrine regulation of energy metabolism: Review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; GHRELIN; LEPTIN; LEPTIN RECEPTOR; RESISTIN;

EID: 4344607526     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2004.032482     Document Type: Review
Times cited : (832)

References (136)
  • 1
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature 1998;22:763-70.
    • (1998) Nature , vol.22 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 3
    • 0036963628 scopus 로고    scopus 로고
    • Leptin - From a signal of adiposity to a hormone mediator in peripheral tissues
    • Baratta M. Leptin - from a signal of adiposity to a hormone mediator in peripheral tissues. Med Sci Monit 2002;8:RA282-92.
    • (2002) Med Sci Monit , vol.8
    • Baratta, M.1
  • 4
    • 0037590894 scopus 로고    scopus 로고
    • Energy balance in obesity
    • Webber J. Energy balance in obesity. Proc Nutr Soc 2003;62: 539-43.
    • (2003) Proc Nutr Soc , vol.62 , pp. 539-543
    • Webber, J.1
  • 5
    • 0034534905 scopus 로고    scopus 로고
    • Expression of the long and short leptin receptor isoforms in peripheral blood mononuclear cells: Implications for leptin's actions
    • Tsiotra PC, Pappa V, Raphis SA, Tsigos C. Expression of the long and short leptin receptor isoforms in peripheral blood mononuclear cells: implications for leptin's actions. Metabolism 2000; 49:1537-41.
    • (2000) Metabolism , vol.49 , pp. 1537-1541
    • Tsiotra, P.C.1    Pappa, V.2    Raphis, S.A.3    Tsigos, C.4
  • 8
    • 0034008963 scopus 로고    scopus 로고
    • Measurement of leptin and leptin binding in the human circulation
    • Wallace AM. Measurement of leptin and leptin binding in the human circulation. Ann Clin Biochem 2000;37:244-52.
    • (2000) Ann Clin Biochem , vol.37 , pp. 244-252
    • Wallace, A.M.1
  • 9
    • 0038076280 scopus 로고    scopus 로고
    • Distribution, function, and properties of leptin receptors in the brain
    • Funahashi H, Yada T, Suzuki R, Shioda S. Distribution, function, and properties of leptin receptors in the brain. Int Rev Cytol 2003;224:1-27.
    • (2003) Int Rev Cytol , vol.224 , pp. 1-27
    • Funahashi, H.1    Yada, T.2    Suzuki, R.3    Shioda, S.4
  • 10
    • 0037233878 scopus 로고    scopus 로고
    • Serum ghrelin levels in obese patients: The relationship to serum leptin levels and soluble leptin receptor levels
    • Rosicka M, Krsek M, Matoulek M, Jarkovska Z, Marek J, Justova V, et al. Serum ghrelin levels in obese patients: the relationship to serum leptin levels and soluble leptin receptor levels. Physiol Res 2003;52:61-6.
    • (2003) Physiol Res , vol.52 , pp. 61-66
    • Rosicka, M.1    Krsek, M.2    Matoulek, M.3    Jarkovska, Z.4    Marek, J.5    Justova, V.6
  • 11
    • 0032747280 scopus 로고    scopus 로고
    • Recombinant leptin for weight loss in obese and lean adults: A randomized, controlled, dose-escalation trial
    • Heymsfield SB, Greenberg AS, Fujioka K, Dixon RM, Kushner R, Hunt T, et al. Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial. JAMA 1999;282:1568-75.
    • (1999) JAMA , vol.282 , pp. 1568-1575
    • Heymsfield, S.B.1    Greenberg, A.S.2    Fujioka, K.3    Dixon, R.M.4    Kushner, R.5    Hunt, T.6
  • 12
    • 0033931981 scopus 로고    scopus 로고
    • Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity
    • El-Haschimi K, Pierroz DD, Hileman SM, Bjorback C, Flier JS. Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity, J Clin Invest 2000;105:1827-32.
    • (2000) J Clin Invest , vol.105 , pp. 1827-1832
    • El-Haschimi, K.1    Pierroz, D.D.2    Hileman, S.M.3    Bjorback, C.4    Flier, J.S.5
  • 14
  • 16
    • 0037301932 scopus 로고    scopus 로고
    • Hormonal control of the neuropeptide Y system
    • Magni P. Hormonal control of the neuropeptide Y system. Curr Protein Pept Sci 2003;4:45-57.
    • (2003) Curr Protein Pept Sci , vol.4 , pp. 45-57
    • Magni, P.1
  • 18
    • 0029941188 scopus 로고    scopus 로고
    • Role of NPY neurones in GH-dependent feedback signalling to the brain
    • Chan YY, Clifton DK, Steiner RA. Role of NPY neurones in GH-dependent feedback signalling to the brain. Horm Res 1996; 145:12-4.
    • (1996) Horm Res , vol.145 , pp. 12-14
    • Chan, Y.Y.1    Clifton, D.K.2    Steiner, R.A.3
  • 19
    • 0032899005 scopus 로고    scopus 로고
    • Many LH peaks are needed to physiologically stimulate testosterone secretion: Modulation by fasting and NPY
    • Pierroz DD, Aebi AC, Huhtaniemi IT, Aubert ML. Many LH peaks are needed to physiologically stimulate testosterone secretion: modulation by fasting and NPY. Am J Physiol 1999;276:E603-10.
    • (1999) Am J Physiol , vol.276
    • Pierroz, D.D.1    Aebi, A.C.2    Huhtaniemi, I.T.3    Aubert, M.L.4
  • 20
    • 0036116417 scopus 로고    scopus 로고
    • Aspects of the neuroendocrine regulation of body weight homeostasis
    • Rohner-Jeanrenaud F. Aspects of the neuroendocrine regulation of body weight homeostasis. Am Endocrinol 2002;63:125-8.
    • (2002) Am Endocrinol , vol.63 , pp. 125-128
    • Rohner-Jeanrenaud, F.1
  • 23
    • 0036870538 scopus 로고    scopus 로고
    • Does body mass play a role in the regulation of food intake?
    • Speakman JR, Stubbs RJ, Mercer JG. Does body mass play a role in the regulation of food intake? Proc Nutr Soc 2002;61:473-87.
    • (2002) Proc Nutr Soc , vol.61 , pp. 473-487
    • Speakman, J.R.1    Stubbs, R.J.2    Mercer, J.G.3
  • 25
    • 0041802722 scopus 로고    scopus 로고
    • Characterization of leptin pulse dynamics and relationship to fat mass, growth hormone, cortisol, and insulin
    • Koutkia P, Canavan B, Johnson ML, DePaoli A, Grinspoon S. Characterization of leptin pulse dynamics and relationship to fat mass, growth hormone, cortisol, and insulin. Am J Physiol Endocrinol Metab 2003;285:E372-9.
    • (2003) Am J Physiol Endocrinol Metab , vol.285
    • Koutkia, P.1    Canavan, B.2    Johnson, M.L.3    DePaoli, A.4    Grinspoon, S.5
  • 26
    • 0036791464 scopus 로고    scopus 로고
    • The role of leptin in the control of body weight
    • Leibel RL. The role of leptin in the control of body weight. Nutr Rev 2002;60:315-9, discussion S68-84, 85-7.
    • (2002) Nutr Rev , vol.60 , pp. 315-319
    • Leibel, R.L.1
  • 28
    • 0036871125 scopus 로고    scopus 로고
    • Recent advances in the physiology of eating
    • French S, Castiglione K. Recent advances in the physiology of eating. Proc Nutr Soc 2002;61:489-96.
    • (2002) Proc Nutr Soc , vol.61 , pp. 489-496
    • French, S.1    Castiglione, K.2
  • 30
    • 0037269657 scopus 로고    scopus 로고
    • Leptin-induced weight loss is not solely mediated by anorexia
    • Dötsch J, Meissner U, Rascher W. Leptin-induced weight loss is not solely mediated by anorexia. Eur J Endocrinol 2003;148:11-2.
    • (2003) Eur J Endocrinol , vol.148 , pp. 11-12
    • Dötsch, J.1    Meissner, U.2    Rascher, W.3
  • 32
    • 0029860791 scopus 로고    scopus 로고
    • Modulation of insulin activities by leptin
    • Cohen B, Novick D, Rubinstein M. Modulation of insulin activities by leptin. Science 1996;274:1185-8.
    • (1996) Science , vol.274 , pp. 1185-1188
    • Cohen, B.1    Novick, D.2    Rubinstein, M.3
  • 33
  • 34
    • 0036168190 scopus 로고    scopus 로고
    • Characterization of short isoforms of the leptin receptor in rat cerebral microvessels and of brain uptake of leptin in mouse models of obesity
    • Hileman SM, Pierroz DD, Masuzaki H, Bjorback C, El-Haschimi K, Banks WA, et al. Characterization of short isoforms of the leptin receptor in rat cerebral microvessels and of brain uptake of leptin in mouse models of obesity. Endocrinology 2002;143:775-83.
    • (2002) Endocrinology , vol.143 , pp. 775-783
    • Hileman, S.M.1    Pierroz, D.D.2    Masuzaki, H.3    Bjorback, C.4    El-Haschimi, K.5    Banks, W.A.6
  • 35
    • 17744388106 scopus 로고    scopus 로고
    • Transcellular transport of leptin by the short leptin receptor isoform ObRa in Madin-Darby canine kidney cells
    • Hileman SM, Tornoe J, Flier JS, Bjorback C. Transcellular transport of leptin by the short leptin receptor isoform ObRa in Madin-Darby canine kidney cells. Endocrinology 2000;141:1955-61.
    • (2000) Endocrinology , vol.141 , pp. 1955-1961
    • Hileman, S.M.1    Tornoe, J.2    Flier, J.S.3    Bjorback, C.4
  • 36
    • 0037195916 scopus 로고    scopus 로고
    • Generation of soluble leptin receptor by ectodomain shedding of membrane-spanning receptors in vitro and in vivo
    • Ge HF, Huang L, Pourbahram T, Li C. Generation of soluble leptin receptor by ectodomain shedding of membrane-spanning receptors in vitro and in vivo. J Biol Chem 2002;277:45898-903.
    • (2002) J Biol Chem , vol.277 , pp. 45898-45903
    • Ge, H.F.1    Huang, L.2    Pourbahram, T.3    Li, C.4
  • 37
    • 0035794211 scopus 로고    scopus 로고
    • Modulation of circulating leptin levels by its soluble receptor
    • Huang L, Wang Z, Li C. Modulation of circulating leptin levels by its soluble receptor. J Biol Chem 2001;276:6343-9.
    • (2001) J Biol Chem , vol.276 , pp. 6343-6349
    • Huang, L.1    Wang, Z.2    Li, C.3
  • 39
    • 0037381982 scopus 로고    scopus 로고
    • Adiponectin: Stability in plasma over 36 hours and within-person variation over 1 year
    • Pischon T, Hotamisligil GS, Rimm E. Adiponectin: stability in plasma over 36 hours and within-person variation over 1 year. Clin Chem 2003;49:650-2.
    • (2003) Clin Chem , vol.49 , pp. 650-652
    • Pischon, T.1    Hotamisligil, G.S.2    Rimm, E.3
  • 42
    • 0034087734 scopus 로고    scopus 로고
    • Serum leptin levels in patients with hyperlipidemias
    • Haluzik M, Fiedler J, Nedvidkova J, Ceska R. Serum leptin levels in patients with hyperlipidemias. Nutrition 2000;16:429-33.
    • (2000) Nutrition , vol.16 , pp. 429-433
    • Haluzik, M.1    Fiedler, J.2    Nedvidkova, J.3    Ceska, R.4
  • 43
    • 0003156924 scopus 로고    scopus 로고
    • Reference ranges of serum leptin
    • Blum WF, et al., eds. Heidelberg: Johann Ambrosius Verlag
    • Blum WF, Juul A. Reference ranges of serum leptin. In: Blum WF, et al., eds. Leptin - the voice of adipose tissue. Heidelberg: Johann Ambrosius Verlag, 1997:318-26.
    • (1997) Leptin - The Voice of Adipose Tissue , pp. 318-326
    • Blum, W.F.1    Juul, A.2
  • 44
    • 0942279569 scopus 로고    scopus 로고
    • Energy homeostasis, obesity and eating disorders: Recent advances in endocrinology
    • Gale SM, Castracane VD, Mantzoros CS. Energy homeostasis, obesity and eating disorders: recent advances in endocrinology. J Nutr 2004;134:295-8.
    • (2004) J Nutr , vol.134 , pp. 295-298
    • Gale, S.M.1    Castracane, V.D.2    Mantzoros, C.S.3
  • 46
    • 0842312989 scopus 로고    scopus 로고
    • Simultaneous and continuous 24-hour plasma and cerebrospinal fluid leptin measurements: Dissociation of concentrations in central and peripheral compartments
    • Wong ML, Licinio J, Yildiz BO, Mantzoros CS, Prolo P, Kling M, et al. Simultaneous and continuous 24-hour plasma and cerebrospinal fluid leptin measurements: dissociation of concentrations in central and peripheral compartments. J Clin Endocrinol Metab 2004;89:258-65.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 258-265
    • Wong, M.L.1    Licinio, J.2    Yildiz, B.O.3    Mantzoros, C.S.4    Prolo, P.5    Kling, M.6
  • 47
    • 0346157283 scopus 로고    scopus 로고
    • The involvement of the blood-brain and the blood-cerebrospinal fluid barriers in the distribution of leptin into and out of the rat brain
    • Kurrimbux D, Gaffen Z, Farrell CL, Martin D, Thomas SA. The involvement of the blood-brain and the blood-cerebrospinal fluid barriers in the distribution of leptin into and out of the rat brain. Neuroscience 2004;123:527-36.
    • (2004) Neuroscience , vol.123 , pp. 527-536
    • Kurrimbux, D.1    Gaffen, Z.2    Farrell, C.L.3    Martin, D.4    Thomas, S.A.5
  • 48
    • 0036293591 scopus 로고    scopus 로고
    • Leptin signaling, adiposity, and energy balance
    • Jequier E. Leptin signaling, adiposity, and energy balance. Ann N Y Acad Sci 2002;967:379-88.
    • (2002) Ann N Y Acad Sci , vol.967 , pp. 379-388
    • Jequier, E.1
  • 49
    • 0842328001 scopus 로고    scopus 로고
    • Update on adipocyte hormones: Regulation of energy balance and carbohydrate/lipid metabolism
    • Havel PJ. Update on adipocyte hormones: regulation of energy balance and carbohydrate/lipid metabolism. Diabetes 2004; 53(Suppl 1):S143-51.
    • (2004) Diabetes , vol.53 , Issue.1 SUPPL.
    • Havel, P.J.1
  • 50
    • 3042534522 scopus 로고    scopus 로고
    • Soluble leptin receptor and soluble receptor-bound fraction of leptin in the metabolic syndrome
    • Sandhofer A, Laimer M, Ebenbichler CF, Kaser S, Paulweber B, Patsch JR. Soluble leptin receptor and soluble receptor-bound fraction of leptin in the metabolic syndrome. Obes Res 2003; 11:760-8.
    • (2003) Obes Res , vol.11 , pp. 760-768
    • Sandhofer, A.1    Laimer, M.2    Ebenbichler, C.F.3    Kaser, S.4    Paulweber, B.5    Patsch, J.R.6
  • 51
    • 12244309089 scopus 로고    scopus 로고
    • Elevated serum levels of leptin and leptin receptor in patients with advanced chronic heart failure
    • Schulze PC, Kratzsch J, Linke A, Schoene N, Adams V, Gielen S, et al. Elevated serum levels of leptin and leptin receptor in patients with advanced chronic heart failure. Eur J Heart Fail 2003;5:33-40.
    • (2003) Eur J Heart Fail , vol.5 , pp. 33-40
    • Schulze, P.C.1    Kratzsch, J.2    Linke, A.3    Schoene, N.4    Adams, V.5    Gielen, S.6
  • 54
    • 0346949031 scopus 로고    scopus 로고
    • Structural divergence of human ghrelin. Identification of multiple ghrelin-derived molecules produced by posttranslational processing
    • Hosoda H, Kojima M, Mitzushima T, Shimizu S, Kangawa K. Structural divergence of human ghrelin. Identification of multiple ghrelin-derived molecules produced by posttranslational processing. J Biol Chem 2003;278:67-70.
    • (2003) J Biol Chem , vol.278 , pp. 67-70
    • Hosoda, H.1    Kojima, M.2    Mitzushima, T.3    Shimizu, S.4    Kangawa, K.5
  • 55
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M, Hosoda H, Date Y. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999;402: 656-60.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3
  • 56
    • 0013493636 scopus 로고    scopus 로고
    • Ghrelin: The link connecting growth with metabolism and energy homeostasis
    • Casanueva FF, Dieguez C. Ghrelin: the link connecting growth with metabolism and energy homeostasis. Rev Endocrinol Metab Disord 2002;3:326-38.
    • (2002) Rev Endocrinol Metab Disord , vol.3 , pp. 326-338
    • Casanueva, F.F.1    Dieguez, C.2
  • 57
    • 0036977178 scopus 로고    scopus 로고
    • Structure and regulation of the growth hormone secretagogue receptor
    • Petersenn S. Structure and regulation of the growth hormone secretagogue receptor. Minerva Endocrinol 2002;27:243-56.
    • (2002) Minerva Endocrinol , vol.27 , pp. 243-256
    • Petersenn, S.1
  • 58
    • 0141522754 scopus 로고    scopus 로고
    • Appetite regulation by ghrelin - A novel neuro-endocrine gastric peptide hormone in the gut-brain-axis
    • Hagemann D, Meier JJ, Gallwitz B, Schmidt WE. Appetite regulation by ghrelin - a novel neuro-endocrine gastric peptide hormone in the gut-brain-axis [Review]. Z Gastroenterol 2003;41: 929-36.
    • (2003) Z Gastroenterol , vol.41 , pp. 929-936
    • Hagemann, D.1    Meier, J.J.2    Gallwitz, B.3    Schmidt, W.E.4
  • 60
    • 0642272476 scopus 로고    scopus 로고
    • Ghrelin: A recently discovered gut-brain peptide
    • Lazarczyk MA, Lazarczyk M, Grzela T. Ghrelin: a recently discovered gut-brain peptide. Int J Mol Med 2003;12:279-87.
    • (2003) Int J Mol Med , vol.12 , pp. 279-287
    • Lazarczyk, M.A.1    Lazarczyk, M.2    Grzela, T.3
  • 61
    • 0036904031 scopus 로고    scopus 로고
    • Ghrelin, an orexigenic signaling molecule from the gastrointestinal tract
    • Kojima M, Kangawa K. Ghrelin, an orexigenic signaling molecule from the gastrointestinal tract. Curr Opin Pharmacol 2002;2: 665-8.
    • (2002) Curr Opin Pharmacol , vol.2 , pp. 665-668
    • Kojima, M.1    Kangawa, K.2
  • 62
    • 0037066587 scopus 로고    scopus 로고
    • Neurodendocrine and peripheral activities of ghrelin: Implications in metabolism and obesity
    • Muccioli G, Tschöp M, Papotti M, Dghenghi R, Heiman M, Ghigo E. Neurodendocrine and peripheral activities of ghrelin: implications in metabolism and obesity. Eur J Pharmacol 2002;440: 235-54.
    • (2002) Eur J Pharmacol , vol.440 , pp. 235-254
    • Muccioli, G.1    Tschöp, M.2    Papotti, M.3    Dghenghi, R.4    Heiman, M.5    Ghigo, E.6
  • 63
    • 1342317555 scopus 로고    scopus 로고
    • Peripheral signals in the control of satiety and hunger
    • Drazen DL, Woods SC. Peripheral signals in the control of satiety and hunger. Curr Opin Clin Nutr Metab Care 2003;6:621-9.
    • (2003) Curr Opin Clin Nutr Metab Care , vol.6 , pp. 621-629
    • Drazen, D.L.1    Woods, S.C.2
  • 64
    • 0141761123 scopus 로고    scopus 로고
    • Ghrelin, a widespread hormone: Insights into molecular and cellular regulation of its expression and metabolism of action
    • Gualillo O, Lago F, Gomez-Reino J, Casanueva FF, Dieguez C. Ghrelin, a widespread hormone: insights into molecular and cellular regulation of its expression and metabolism of action [Review]. FEBS Lett 2003;552:105-9.
    • (2003) FEBS Lett , vol.552 , pp. 105-109
    • Gualillo, O.1    Lago, F.2    Gomez-Reino, J.3    Casanueva, F.F.4    Dieguez, C.5
  • 65
    • 0043030280 scopus 로고    scopus 로고
    • Minireview: From anorexia to obesity - The yin and yang of body weight control
    • Zigman JM, Elmquist JK. Minireview: from anorexia to obesity - the yin and yang of body weight control. Endocrinology 2003; 144:3749-56.
    • (2003) Endocrinology , vol.144 , pp. 3749-3756
    • Zigman, J.M.1    Elmquist, J.K.2
  • 68
    • 0036263016 scopus 로고    scopus 로고
    • Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity
    • Shuto Y, Shibasaki T, Otagiri A, Kuriyama H, Ohala H, Tamura H, et al. Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity. J Clin Invest 2002;109:1429-36.
    • (2002) J Clin Invest , vol.109 , pp. 1429-1436
    • Shuto, Y.1    Shibasaki, T.2    Otagiri, A.3    Kuriyama, H.4    Ohala, H.5    Tamura, H.6
  • 69
    • 0242660829 scopus 로고    scopus 로고
    • Neuropeptide Y: A physiological orexigen modulated by the feedback action of ghrelin and leptin
    • Kalra SP, Kalra PS. Neuropeptide Y: a physiological orexigen modulated by the feedback action of ghrelin and leptin. Endocrine 2003;22:49-56.
    • (2003) Endocrine , vol.22 , pp. 49-56
    • Kalra, S.P.1    Kalra, P.S.2
  • 70
    • 0036073405 scopus 로고    scopus 로고
    • Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure
    • Banks WA, Tschöp M, Robinson SM, Heiman ML. Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure. J Pharmacol Exp Ther 2002;302:822-7.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 822-827
    • Banks, W.A.1    Tschöp, M.2    Robinson, S.M.3    Heiman, M.L.4
  • 71
    • 0742287004 scopus 로고    scopus 로고
    • Evaluation of the comparability of commercial ghrelin assays
    • Gröschl M, Uhr M, Kraus T. Evaluation of the comparability of commercial ghrelin assays. Clin Chem 2004;50:457-8.
    • (2004) Clin Chem , vol.50 , pp. 457-458
    • Gröschl, M.1    Uhr, M.2    Kraus, T.3
  • 72
    • 0347755156 scopus 로고    scopus 로고
    • Ghrelin levels in obesity and anorexia nervosa: Effect of weight reduction or recuperation
    • Soriano-Guillen L, Barrios V, Campos-Barros A, Argente J. Ghrelin levels in obesity and anorexia nervosa: effect of weight reduction or recuperation. J Pediatr 2004;144:30-5.
    • (2004) J Pediatr , vol.144 , pp. 30-35
    • Soriano-Guillen, L.1    Barrios, V.2    Campos-Barros, A.3    Argente, J.4
  • 73
    • 1942473108 scopus 로고    scopus 로고
    • Plasma ghrelin concentrations are decreased in insulin-resistant obese adults relative to equally obese insulin-sensitive controls
    • McLaughlin T, Abbasi F, Lamendola C, Frayo RS, Cummings DE. Plasma ghrelin concentrations are decreased in insulin-resistant obese adults relative to equally obese insulin-sensitive controls. J Clin Endocrinol Metab 2004;89:1630-5.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 1630-1635
    • McLaughlin, T.1    Abbasi, F.2    Lamendola, C.3    Frayo, R.S.4    Cummings, D.E.5
  • 74
    • 1942537123 scopus 로고    scopus 로고
    • Growth hormone and ghrelin responses to an oral glucose load in adolescent girls with anorexia nervosa and controls
    • Misra M, Miller KK, Herzog DB, Ramaswamy K, Aggarwal A, Almazan C, et al. Growth hormone and ghrelin responses to an oral glucose load in adolescent girls with anorexia nervosa and controls. J Clin Endocrinol Metab 2004;89:1605-12.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 1605-1612
    • Misra, M.1    Miller, K.K.2    Herzog, D.B.3    Ramaswamy, K.4    Aggarwal, A.5    Almazan, C.6
  • 76
    • 1942437617 scopus 로고    scopus 로고
    • Response of circulating ghrelin levels to insulin therapy in children with newly diagnosed type I diabetes mellitus
    • Soriano-Guillen L, Barrios V, Lechuga-Sancho A, Chowen JA, Argente J. Response of circulating ghrelin levels to insulin therapy in children with newly diagnosed type I diabetes mellitus. Pediatr Res 2004;55:830-5.
    • (2004) Pediatr Res , vol.55 , pp. 830-835
    • Soriano-Guillen, L.1    Barrios, V.2    Lechuga-Sancho, A.3    Chowen, J.A.4    Argente, J.5
  • 77
    • 1442303291 scopus 로고    scopus 로고
    • The relationship between active ghrelin levels and human obesity involves alterations in resting energy expenditure
    • Marzullo P, Verti B, Savia G, Walker GE, Guzzaloni G, Tagliaferri M, et al. the relationship between active ghrelin levels and human obesity involves alterations in resting energy expenditure. J Clin Endocrinol Metab 2004;89:936-9.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 936-939
    • Marzullo, P.1    Verti, B.2    Savia, G.3    Walker, G.E.4    Guzzaloni, G.5    Tagliaferri, M.6
  • 79
    • 1642354552 scopus 로고    scopus 로고
    • Ghrelin: Integrative neuroendocrine peptide in health and disease
    • Wu JT, Kral JG. Ghrelin: integrative neuroendocrine peptide in health and disease. Ann Surg 2004;239:464-74.
    • (2004) Ann Surg , vol.239 , pp. 464-474
    • Wu, J.T.1    Kral, J.G.2
  • 80
    • 0037232608 scopus 로고    scopus 로고
    • Endocrine and non-endocrine actions of ghrelin
    • Broglio F, Gottero C, Arvat E, Ghigo E. Endocrine and non-endocrine actions of ghrelin. Horm Res 2003;59:109-17.
    • (2003) Horm Res , vol.59 , pp. 109-117
    • Broglio, F.1    Gottero, C.2    Arvat, E.3    Ghigo, E.4
  • 81
    • 0347358002 scopus 로고    scopus 로고
    • Gastrointestinal satiety signals I. An overview of gastrointestinal signals that influence food intake
    • Woods SC. Gastrointestinal satiety signals I. An overview of gastrointestinal signals that influence food intake. Am J Physiol Gastrointest Liver Physiol 2004;286:G7-13.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.286
    • Woods, S.C.1
  • 82
    • 4344680499 scopus 로고    scopus 로고
    • Endocrinological activities of ghrelin: New insights
    • Ukkola O. Endocrinological activities of ghrelin: new insights. Eur J Intern Med 2003;14:351-6.
    • (2003) Eur J Intern Med , vol.14 , pp. 351-356
    • Ukkola, O.1
  • 83
    • 0036511213 scopus 로고    scopus 로고
    • ACRP 30/adiponectin: An adipokine regulating glucose and lipid metabolism
    • Berg AH, Combs TP, Scherer PE. ACRP 30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab 2002;13:84-9.
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 84-89
    • Berg, A.H.1    Combs, T.P.2    Scherer, P.E.3
  • 84
    • 0032510463 scopus 로고    scopus 로고
    • The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor
    • Shapiro L, Scherer PE. The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor. Curr Biol 1998;12:335-8.
    • (1998) Curr Biol , vol.12 , pp. 335-338
    • Shapiro, L.1    Scherer, P.E.2
  • 85
    • 0037494960 scopus 로고    scopus 로고
    • Cloning of adiponectin receptors that mediate anti-diabetic metabolic effects
    • Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, et al. Cloning of adiponectin receptors that mediate anti-diabetic metabolic effects. Nature 2003;423:762-9.
    • (2003) Nature , vol.423 , pp. 762-769
    • Yamauchi, T.1    Kamon, J.2    Ito, Y.3    Tsuchida, A.4    Yokomizo, T.5    Kita, S.6
  • 86
    • 3142761477 scopus 로고    scopus 로고
    • T-Cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin
    • Hug C, Wang J, Ahmad NS, Bogan JS, Tsao TS, Lodish HF. T-Cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin. Proc Natl Acad Sci USA 2004; 101:10308-13.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10308-10313
    • Hug, C.1    Wang, J.2    Ahmad, N.S.3    Bogan, J.S.4    Tsao, T.S.5    Lodish, H.F.6
  • 87
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp 30 enhances hepatic insulin action
    • Berg AH, Combs TP, Du X, Brownlee M, Scherer PE. The adipocyte-secreted protein Acrp 30 enhances hepatic insulin action. Nat Med 2001;7:947-53.
    • (2001) Nat Med , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 88
    • 0037059013 scopus 로고    scopus 로고
    • Enhanced muscle fat oxidation and glucose transport by ACRP 30 globular domain: Acetyl CoA carboxylase inhibition and AMP-activated protein kinase activation
    • Tomas E, Tsao TS, Saha AK, Murrey HE, Zhang CC, Itani SL, et al. Enhanced muscle fat oxidation and glucose transport by ACRP 30 globular domain: acetyl CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Acad Sci USA 2002;99:16309-13.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16309-16313
    • Tomas, E.1    Tsao, T.S.2    Saha, A.K.3    Murrey, H.E.4    Zhang, C.C.5    Itani, S.L.6
  • 89
    • 0038439261 scopus 로고    scopus 로고
    • Plasma acylation-stimulating protein, adiponectin, leptin, and ghrelin before and after weight loss induced by gastric bypass surgery in morbidly obese subjects
    • Faraj M, Havel PJ, Phelis S, Blanck D, Snideman AD, Cianflone K. Plasma acylation-stimulating protein, adiponectin, leptin, and ghrelin before and after weight loss induced by gastric bypass surgery in morbidly obese subjects. J Clin Endocrinol Metab 2003;88:1594-602.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1594-1602
    • Faraj, M.1    Havel, P.J.2    Phelis, S.3    Blanck, D.4    Snideman, A.D.5    Cianflone, K.6
  • 91
    • 0036875149 scopus 로고    scopus 로고
    • Relationship between serum adiponectin concentration and intramyocellular lipid stores in humans
    • Thamer C, Machann J, Tschritter O, Haap M, Wietek B, Haring HU, et al. Relationship between serum adiponectin concentration and intramyocellular lipid stores in humans. Horm Metab Res 2002;34:646-9.
    • (2002) Horm Metab Res , vol.34 , pp. 646-649
    • Thamer, C.1    Machann, J.2    Tschritter, O.3    Haap, M.4    Wietek, B.5    Haring, H.U.6
  • 92
    • 0034881956 scopus 로고    scopus 로고
    • You are what you secrete
    • Saltiel AR. You are what you secrete. Nat Med 2001;7:887-8.
    • (2001) Nat Med , vol.7 , pp. 887-888
    • Saltiel, A.R.1
  • 94
    • 0035462629 scopus 로고    scopus 로고
    • PPARγ ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein
    • Maeda N, Takahashi M, Fuhahashi T, Kihara S, Nishizawa H, Kishida K, et al. PPARγ ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes 2001;50:2094-9.
    • (2001) Diabetes , vol.50 , pp. 2094-2099
    • Maeda, N.1    Takahashi, M.2    Fuhahashi, T.3    Kihara, S.4    Nishizawa, H.5    Kishida, K.6
  • 95
    • 0041374029 scopus 로고    scopus 로고
    • Insulin resistance in adipose tissue: Direct and indirect effects of TNF-α
    • Ruan H, Lodish HF. Insulin resistance in adipose tissue: direct and indirect effects of TNF-α. Cytokine Growth Factor Rev 2003; 14:447-55.
    • (2003) Cytokine Growth Factor Rev , vol.14 , pp. 447-455
    • Ruan, H.1    Lodish, H.F.2
  • 96
    • 0037768826 scopus 로고    scopus 로고
    • Thiazolidinediones - Some recent developments
    • Stumvoll M. Thiazolidinediones - some recent developments. Expert Opin Investig Drugs 2003;12:1179-87.
    • (2003) Expert Opin Investig Drugs , vol.12 , pp. 1179-1187
    • Stumvoll, M.1
  • 97
    • 0042320948 scopus 로고    scopus 로고
    • Peripheral, but not central, administration of adiponectin reduces visceral adiposity and upregulates the expression of uncoupling protein in agouti yellow (Ay/a) obese mice
    • Masaki T, Chiba S, Yasuda T, Tsubone T, Kakuma T, Shimomura I, et al. Peripheral, but not central, administration of adiponectin reduces visceral adiposity and upregulates the expression of uncoupling protein in agouti yellow (Ay/a) obese mice. Diabetes 2003;52:2266-73.
    • (2003) Diabetes , vol.52 , pp. 2266-2273
    • Masaki, T.1    Chiba, S.2    Yasuda, T.3    Tsubone, T.4    Kakuma, T.5    Shimomura, I.6
  • 98
    • 0344081177 scopus 로고    scopus 로고
    • Minireview: The AMP-activated protein kinase cascade: The key sensor of cellular energy status
    • Hardie DG. Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status. Endocrinology 2003;144:5179-83.
    • (2003) Endocrinology , vol.144 , pp. 5179-5183
    • Hardie, D.G.1
  • 99
    • 0036266897 scopus 로고    scopus 로고
    • Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration prevents a decrease in wholebody insulin sensitivity in humans
    • Stefan N, Vozarova B, Funahashi T, Matsuzawa Y, Weyer C, Lindsay RS, et al. Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration prevents a decrease in wholebody insulin sensitivity in humans. Diabetes 2002;51:1884-8.
    • (2002) Diabetes , vol.51 , pp. 1884-1888
    • Stefan, N.1    Vozarova, B.2    Funahashi, T.3    Matsuzawa, Y.4    Weyer, C.5    Lindsay, R.S.6
  • 101
    • 0037020170 scopus 로고    scopus 로고
    • Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis
    • Matsuda M, Shimomura I, Sata M, Arita Y, Nishida K, Matsuzawa Y, et al. Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis. J Biol Chem 2002;277: 37487-91.
    • (2002) J Biol Chem , vol.277 , pp. 37487-37491
    • Matsuda, M.1    Shimomura, I.2    Sata, M.3    Arita, Y.4    Nishida, K.5    Matsuzawa, Y.6
  • 102
    • 0035957040 scopus 로고    scopus 로고
    • Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class a scavenger receptor expression in human monocyte-derived macrophages
    • Ouchi N, Kihara S, Arita Y, Nishida M, Matsuyama A, Matsuzawa Y, et al. Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation 2001;103:1057-63.
    • (2001) Circulation , vol.103 , pp. 1057-1063
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3    Nishida, M.4    Matsuyama, A.5    Matsuzawa, Y.6
  • 103
    • 10744228583 scopus 로고    scopus 로고
    • Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin
    • Kamada Y, Tamura S, Kiso S, Matsumoto H, Saji Y, Yoshida Y, et al. Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin. Gastroenterology 2003;125:1796-807.
    • (2003) Gastroenterology , vol.125 , pp. 1796-1807
    • Kamada, Y.1    Tamura, S.2    Kiso, S.3    Matsumoto, H.4    Saji, Y.5    Yoshida, Y.6
  • 104
  • 105
    • 0141448772 scopus 로고    scopus 로고
    • Adipokines, inflammation, and the endothelium in diabetes
    • Aldhahi W, Hamdy O. Adipokines, inflammation, and the endothelium in diabetes. Curr Diab Rep 2003;3:293-8.
    • (2003) Curr Diab Rep , vol.3 , pp. 293-298
    • Aldhahi, W.1    Hamdy, O.2
  • 107
    • 1642533456 scopus 로고    scopus 로고
    • Evaluation of an enzyme immunometric assay to measure serum adiponectin concentrations
    • Suominen P. Evaluation of an enzyme immunometric assay to measure serum adiponectin concentrations. Clin Chem 2004; 50:219-21.
    • (2004) Clin Chem , vol.50 , pp. 219-221
    • Suominen, P.1
  • 109
    • 0038293399 scopus 로고    scopus 로고
    • Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: Evidence for independent roles of age and sex
    • Cnop M, Havel PJ, Utzschneider KM, Carr DB, Sinha MK, Boyko EJ, et al. Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex. Diabetologica 2003;46:459-69.
    • (2003) Diabetologica , vol.46 , pp. 459-469
    • Cnop, M.1    Havel, P.J.2    Utzschneider, K.M.3    Carr, D.B.4    Sinha, M.K.5    Boyko, E.J.6
  • 110
    • 0034891684 scopus 로고    scopus 로고
    • Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin
    • Yang WS, Lee WJ, Funahashi T, Tanaka S, Matsuzawa Y, Chao CL, et al. Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. J Clin Endocrinol Metab 2001;86:3815-9.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3815-3819
    • Yang, W.S.1    Lee, W.J.2    Funahashi, T.3    Tanaka, S.4    Matsuzawa, Y.5    Chao, C.L.6
  • 111
    • 0034999667 scopus 로고    scopus 로고
    • Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia
    • Weyer C, Funahashi T, Tanaka S, Hotta K, Matsuzawa Y, Pratley RE, et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 2001;86:1930-5.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1930-1935
    • Weyer, C.1    Funahashi, T.2    Tanaka, S.3    Hotta, K.4    Matsuzawa, Y.5    Pratley, R.E.6
  • 112
    • 0242329843 scopus 로고    scopus 로고
    • Adiponectin: Linking the fat cell to insulin sensitivity
    • Goldfine A, Kahn CR. Adiponectin: linking the fat cell to insulin sensitivity. Lancet 2003;362:1431-2.
    • (2003) Lancet , vol.362 , pp. 1431-1432
    • Goldfine, A.1    Kahn, C.R.2
  • 113
    • 0036299262 scopus 로고    scopus 로고
    • Increased fat intake, impaired fat oxidation, and failure of fat cell proliferation result in ectopic fat storage, insulin resistance, and type 2 diabetes mellitus
    • Ravussin E, Smith SR. Increased fat intake, impaired fat oxidation, and failure of fat cell proliferation result in ectopic fat storage, insulin resistance, and type 2 diabetes mellitus. Ann N Y Acad Sci 2002;967:363-78.
    • (2002) Ann N Y Acad Sci , vol.967 , pp. 363-378
    • Ravussin, E.1    Smith, S.R.2
  • 115
    • 10744232016 scopus 로고    scopus 로고
    • Decreased plasma concentration of a novel anti-inflammatory protein adiponectin in hypertensive men with coronary artery disease
    • Dzielinska Z, Januszewicz A, Wiecek A, Demkow M, Makowiecka-Ciesla M, Ruzyllo W, et al. Decreased plasma concentration of a novel anti-inflammatory protein adiponectin in hypertensive men with coronary artery disease. Thromb Res 2003;110:365-9.
    • (2003) Thromb Res , vol.110 , pp. 365-369
    • Dzielinska, Z.1    Januszewicz, A.2    Wiecek, A.3    Demkow, M.4    Makowiecka-Ciesla, M.5    Ruzyllo, W.6
  • 116
    • 0042820167 scopus 로고    scopus 로고
    • Human recombinant resistin protein displays a tendency to aggregate by forming intermolecular disulfide linkages
    • Aruna B, Ghosh S, Singh AK, Mande SC, Srinivas V, Chauhan R, et al. Human recombinant resistin protein displays a tendency to aggregate by forming intermolecular disulfide linkages. Biochemistry 2003;42:10554-9.
    • (2003) Biochemistry , vol.42 , pp. 10554-10559
    • Aruna, B.1    Ghosh, S.2    Singh, A.K.3    Mande, S.C.4    Srinivas, V.5    Chauhan, R.6
  • 117
    • 0034254655 scopus 로고    scopus 로고
    • FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family
    • Holcomb IN, Kabakoff RC, Chan B, Baker TW, Gurney A, Henzel W, et al. FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family. EMBO J 2000;19:4046-55.
    • (2000) EMBO J , vol.19 , pp. 4046-4055
    • Holcomb, I.N.1    Kabakoff, R.C.2    Chan, B.3    Baker, T.W.4    Gurney, A.5    Henzel, W.6
  • 119
    • 0036020512 scopus 로고    scopus 로고
    • Cell type-specific expression and coregulation of murine resistin and resistin-like molecule-α in adipose tissue
    • Rajala MW, Lin Y, Ranalletta M, Yang XM, Qian H, Gingerich R, et al. Cell type-specific expression and coregulation of murine resistin and resistin-like molecule-α in adipose tissue. Mol Endocrinol 2002;16:1920-30.
    • (2002) Mol Endocrinol , vol.16 , pp. 1920-1930
    • Rajala, M.W.1    Lin, Y.2    Ranalletta, M.3    Yang, X.M.4    Qian, H.5    Gingerich, R.6
  • 121
    • 0035905772 scopus 로고    scopus 로고
    • Diabetes: The missing link with obesity?
    • Flier JS. Diabetes: the missing link with obesity? Nature 2001; 409:292-3.
    • (2001) Nature , vol.409 , pp. 292-293
    • Flier, J.S.1
  • 122
    • 0036854472 scopus 로고    scopus 로고
    • Resistin - A mediator of obesity-associated insulin resistance or an innocent bystander?
    • Ukkola O. Resistin - a mediator of obesity-associated insulin resistance or an innocent bystander? Eur J Endocrinol 2002; 147:571-4.
    • (2002) Eur J Endocrinol , vol.147 , pp. 571-574
    • Ukkola, O.1
  • 123
    • 0035522298 scopus 로고    scopus 로고
    • Resistin, obesity, and insulin resistance - The emerging role of the adipocyte as an endocrine organ
    • Shuldiner AR, Yang R, Gong D-W. Resistin, obesity, and insulin resistance - the emerging role of the adipocyte as an endocrine organ. N Engl J Med 2001;345:1345-6.
    • (2001) N Engl J Med , vol.345 , pp. 1345-1346
    • Shuldiner, A.R.1    Yang, R.2    Gong, D.-W.3
  • 124
    • 0242641149 scopus 로고    scopus 로고
    • Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor γ agonists
    • Way JM, Gorgun CZ, TongQ, Uysal KT, Brown KK, Harrington WW, et al. Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor γ agonists. J Biol Chem 2001;276:25651-3.
    • (2001) J Biol Chem , vol.276 , pp. 25651-25653
    • Way, J.M.1    Gorgun, C.Z.2    Tong, Q.3    Uysal, K.T.4    Brown, K.K.5    Harrington, W.W.6
  • 127
    • 0037237719 scopus 로고    scopus 로고
    • The irresistible biology of resistin
    • Hotamisligil G. The irresistible biology of resistin. J Clin Invest 2003;111:173-4.
    • (2003) J Clin Invest , vol.111 , pp. 173-174
    • Hotamisligil, G.1
  • 128
    • 0035487109 scopus 로고    scopus 로고
    • Resistin/FIZZ3 expression in relation to obesity and peroxisome proliferator-activated receptor-γ action in humans
    • Savage DB, Sewter CP, Klenk ES, Segal DG, Vidal-Puig A, Considine RV, et al. Resistin/FIZZ3 expression in relation to obesity and peroxisome proliferator-activated receptor-γ action in humans. Diabetes 2001;50:2199-202.
    • (2001) Diabetes , vol.50 , pp. 2199-2202
    • Savage, D.B.1    Sewter, C.P.2    Klenk, E.S.3    Segal, D.G.4    Vidal-Puig, A.5    Considine, R.V.6
  • 129
    • 0036365870 scopus 로고    scopus 로고
    • Resistin gene expression in human adipocytes is not related to insulin resistance
    • Janke J, Engeli S, Gorzelniak K, Luft FC, Sharma AM. Resistin gene expression in human adipocytes is not related to insulin resistance. Obes Res 2002;10:1-5.
    • (2002) Obes Res , vol.10 , pp. 1-5
    • Janke, J.1    Engeli, S.2    Gorzelniak, K.3    Luft, F.C.4    Sharma, A.M.5
  • 130
    • 0035928668 scopus 로고    scopus 로고
    • Do resistin and resistin-like molecules also link obesity to inflammatory diseases?
    • Gomez-Ambrosi J, Fruehbeck G. Do resistin and resistin-like molecules also link obesity to inflammatory diseases? Am Intern Med 2001;135:306-7.
    • (2001) Am Intern Med , vol.135 , pp. 306-307
    • Gomez-Ambrosi, J.1    Fruehbeck, G.2
  • 131
    • 0037241112 scopus 로고    scopus 로고
    • Adipose derived resistin and gut-derived resistin like molecule-β selectively impair insulin action on glucose protection
    • Rajala MW, Obici S, Scherer PhE, Rosseth L. Adipose derived resistin and gut-derived resistin like molecule-β selectively impair insulin action on glucose protection. J Clin Invest 2003;111: 225-30.
    • (2003) J Clin Invest , vol.111 , pp. 225-230
    • Rajala, M.W.1    Obici, S.2    Scherer, Ph.E.3    Rosseth, L.4
  • 132
    • 10744220840 scopus 로고    scopus 로고
    • Plasma resistin concentrations measured by enzyme-linked immunosorbent assay using a newly developed monoclonal antibody are elevated in individuals with type 2 diabetes mellitus
    • Youn BS, Yu KY, Park HU, Lee NS, Min SS, Youn MY, et al. Plasma resistin concentrations measured by enzyme-linked immunosorbent assay using a newly developed monoclonal antibody are elevated in individuals with type 2 diabetes mellitus. J Clin Endocrinol Metab 2004;89:150-6.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 150-156
    • Youn, B.S.1    Yu, K.Y.2    Park, H.U.3    Lee, N.S.4    Min, S.S.5    Youn, M.Y.6
  • 133
    • 2342445056 scopus 로고    scopus 로고
    • Resistin: An adipocyte-derived hormone. Has it a role in diabetes and obesity?
    • Rea R, Donnelly R. Resistin: an adipocyte-derived hormone. Has it a role in diabetes and obesity? Diabetes Obes Metab 2004; 6:163-70.
    • (2004) Diabetes Obes Metab , vol.6 , pp. 163-170
    • Rea, R.1    Donnelly, R.2
  • 136
    • 1842506529 scopus 로고    scopus 로고
    • The current biology of resistin
    • Steppan CM, Lazar MA. The current biology of resistin. J Intern Med 2004;255:439-47.
    • (2004) J Intern Med , vol.255 , pp. 439-447
    • Steppan, C.M.1    Lazar, M.A.2


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