-
1
-
-
52949096557
-
Hypothalamic IKKβ/NF-κB and ER stress link overnutrition to energy imbalance and obesity
-
Zhang, X.; Zhang, G.; Zhang, H.; Karin, M.; Bai, H. and Cai, D. (2008) Hypothalamic IKKβ/NF-κB and ER stress link overnutrition to energy imbalance and obesity. Cell, 135, 61-73.
-
(2008)
Cell
, vol.135
, pp. 61-73
-
-
Zhang, X.1
Zhang, G.2
Zhang, H.3
Karin, M.4
Bai, H.5
Cai, D.6
-
2
-
-
77956666561
-
Adipose tissue inflammation and insulin resistance: All obese humans are not created equal
-
Gauthier, M.S. and Ruderman, NB. (2010) Adipose tissue inflammation and insulin resistance: all obese humans are not created equal. Biochem. J., 430, e1-4.
-
(2010)
Biochem. J.
, vol.430
-
-
Gauthier, M.S.1
Ruderman, N.B.2
-
3
-
-
0036232742
-
Obesity, metabolic syndrome X, and inflammation
-
Das, U.N. (2002) Obesity, metabolic syndrome X, and inflammation. Nutrition, 18, 430-432.
-
(2002)
Nutrition
, vol.18
, pp. 430-432
-
-
Das, U.N.1
-
4
-
-
36849013098
-
Low-grade inflammation, obesity, and insulin resistance in adolescents
-
Herder, C.; Schneitler, S.; Rathmann, W.; Haastert, B.; Schneitler, H.; Winkler, H.; Bredahl, R.; Hahnloser, E. and Martin, S. (2007) Low-grade inflammation, obesity, and insulin resistance in adolescents. J. Clin. Endocrinol. Metab., 92, 4569-4574.
-
(2007)
J. Clin. Endocrinol. Metab.
, vol.92
, pp. 4569-4574
-
-
Herder, C.1
Schneitler, S.2
Rathmann, W.3
Haastert, B.4
Schneitler, H.5
Winkler, H.6
Bredahl, R.7
Hahnloser, E.8
Martin, S.9
-
5
-
-
12344266697
-
How obesity causes diabetes: Not a tall tale
-
Lazar MA. (2005) How obesity causes diabetes: not a tall tale. Science, 307, 373-375.
-
(2005)
Science
, vol.307
, pp. 373-375
-
-
Lazar, M.A.1
-
6
-
-
79953005424
-
Inflammation and insulin resistance: An old story with new ideas
-
Kim, J.K. (2010) Inflammation and insulin resistance: an old story with new ideas. Korean Diabetes J., 34, 137-145.
-
(2010)
Korean Diabetes J
, vol.34
, pp. 137-145
-
-
Kim, J.K.1
-
7
-
-
0033562455
-
Markers of inflammation and prediction of diabetes mellitus in adults [Atherosclerosis Risk in Communities study]: A cohort study
-
Schmidt, M.I.; Duncan, B.B.; Sharrett, A.R.; Lindberg, G.; Savage, P.J.; Offenbacher, S.; Azambuja, M.I.; Tracy, R.P. and Heiss, G. (1999) Markers of inflammation and prediction of diabetes mellitus in adults [Atherosclerosis Risk in Communities study]: a cohort study. Lancet, 353, 1649-1652.
-
(1999)
Lancet
, vol.353
, pp. 1649-1652
-
-
Schmidt, M.I.1
Duncan, B.B.2
Sharrett, A.R.3
Lindberg, G.4
Savage, P.J.5
Offenbacher, S.6
Azambuja, M.I.7
Tracy, R.P.8
Heiss, G.9
-
8
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
Kahn, S.E.; Hull, R.L. and Utzschneider, K.M. (2006) Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature, 444, 840-846.
-
(2006)
Nature
, vol.444
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
9
-
-
77956223799
-
Type 2 diabetes and obesity in adults
-
Whitmore, C. (2010) Type 2 diabetes and obesity in adults. Br. J. Nurs., 19, 882-886.
-
(2010)
Br. J. Nurs.
, vol.19
, pp. 882-886
-
-
Whitmore, C.1
-
10
-
-
77950672195
-
The energetics of obesity: A review: Monitoring energy intake and energy expenditure in humans
-
Sazonov, E.S. and Schuckers, S. (2010) The energetics of obesity: a review: monitoring energy intake and energy expenditure in humans. IEEE Eng. Med. Biol. Mag., 29, 31-35.
-
(2010)
IEEE Eng. Med. Biol. Mag.
, vol.29
, pp. 31-35
-
-
Sazonov, E.S.1
Schuckers, S.2
-
11
-
-
35548943962
-
JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity
-
Solinas, G.; Vilcu, C.; Neels, J.G.; Bandyopadhyay, G.K.; Luo, J.L.; Naugler, W.; Grivennikov, S; Wynshaw-Boris, A; Scadeng, M; Olefsky, J.M. and Karin, M. (2007) JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity. Cell Metab., 6, 386-397.
-
(2007)
Cell Metab
, vol.6
, pp. 386-397
-
-
Solinas, G.1
Vilcu, C.2
Neels, J.G.3
Bandyopadhyay, G.K.4
Luo, J.L.5
Naugler, W.6
Grivennikov, S.7
Wynshaw-Boris, A.8
Scadeng, M.9
Olefsky, J.M.10
Karin, M.11
-
12
-
-
77956383646
-
Cellularity and adipogenic profile of the abdominal subcutaneous adipose tissue from obese adolescents: Association with insulin resistance and hepatic steatosis
-
Kursawe, R.; Eszlinger, M.; Narayan, D.; Liu, T.; Bazuine, M.; Cali, AM.; D'Adamo, E.; Shaw, M.; Pierpont, B.; Shulman, G.I.; Cushman, S.W.; Sherman, A. and Caprio, S. (2010) Cellularity and adipogenic profile of the abdominal subcutaneous adipose tissue from obese adolescents: association with insulin resistance and hepatic steatosis. Diabetes, 59, 2288-2296.
-
(2010)
Diabetes
, vol.59
, pp. 2288-2296
-
-
Kursawe, R.1
Eszlinger, M.2
Narayan, D.3
Liu, T.4
Bazuine, M.5
Cali, A.M.6
D'Adamo, E.7
Shaw, M.8
Pierpont, B.9
Shulman, G.I.10
Cushman, S.W.11
Sherman, A.12
Caprio, S.13
-
13
-
-
0035862334
-
Signal transducer and activator of transcription [STAT]-induced STAT inhibitor 1 [SSI-1]/suppressor of cytokine signalling 1 [SOCS1] inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 [IRS-1] phosphorylation
-
Kawazoe, Y.; Naka, T.; Fujimoto, M.; Kohzaki, H.; Morita, Y.; Narazaki, M.; Okumura, K.; Saitoh, H; Nakagawa, R.; Uchiyama, Y.; Akira, S. and Kishimoto, T. (2001) Signal transducer and activator of transcription [STAT]-induced STAT inhibitor 1 [SSI-1]/suppressor of cytokine signalling 1 [SOCS1] inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 [IRS-1] phosphorylation. J. Exp. Med., 193, 263-269.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 263-269
-
-
Kawazoe, Y.1
Naka, T.2
Fujimoto, M.3
Kohzaki, H.4
Morita, Y.5
Narazaki, M.6
Okumura, K.7
Saitoh, H.8
Nakagawa, R.9
Uchiyama, Y.10
Akira, S.11
Kishimoto, T.12
-
14
-
-
0036228456
-
Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-α
-
Sewter C.; Berger, D.; Considine, R.V.; Medina, G.; Rochford, J.; Ciaraldi, T.; Henry, R.; Dohm, L.; Flier J.S.; O'Rahilly, S. and Vidal-Puig, A.J. (2002) Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-α. Diabetes, 51, 1035-1041.
-
(2002)
Diabetes
, vol.51
, pp. 1035-1041
-
-
Sewter, C.1
Berger, D.2
Considine, R.V.3
Medina, G.4
Rochford, J.5
Ciaraldi, T.6
Henry, R.7
Dohm, L.8
Flier, J.S.9
O'Rahilly, S.10
Vidal-Puig, A.J.11
-
15
-
-
0035029812
-
Regulation by insulin of gene expression in human skeletal muscle and adipose tissue: Evidence for specific defects in type 2 diabetes
-
Ducluzeau, P.H.; Perretti, N.; Laville, M.; Andreelli, F.; Vega, N.; Riou, J.P. and Vidal, H. (2001) Regulation by insulin of gene expression in human skeletal muscle and adipose tissue: evidence for specific defects in type 2 diabetes. Diabetes, 50, 1134-1142.
-
(2001)
Diabetes
, vol.50
, pp. 1134-1142
-
-
Ducluzeau, P.H.1
Perretti, N.2
Laville, M.3
Andreelli, F.4
Vega, N.5
Riou, J.P.6
Vidal, H.7
-
16
-
-
0031963963
-
Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1
-
Kim, J.B.; Sarraf, P.; Wright, M.; Yao, K.M.; Mueller, E.; Solanes, G.; Lowell, B.B. and Spiegelman, B.M. (1998) Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1. J. Clin. Invest., 101, 1-9.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1-9
-
-
Kim, J.B.1
Sarraf, P.2
Wright, M.3
Yao, K.M.4
Mueller, E.5
Solanes, G.6
Lowell, B.B.7
Spiegelman, B.M.8
-
17
-
-
0025945012
-
Insulin resistance--mechanisms, syndromes, and implications
-
Moller, D.E. and Flier, J.S. (1991) Insulin resistance--mechanisms, syndromes, and implications. N. Engl. J. Med., 325, 938-948.
-
(1991)
N. Engl. J. Med.
, vol.325
, pp. 938-948
-
-
Moller, D.E.1
Flier, J.S.2
-
18
-
-
0022861271
-
Regulation of lipoprotein lipase synthesis by recombinant tumor necrosis factorthe primary regulatory role of the hormone in 3T3-L1 adipocytes
-
Price, S.R.; Olivecrona, T. and Pekala, P.H. (1986) Regulation of lipoprotein lipase synthesis by recombinant tumor necrosis factorthe primary regulatory role of the hormone in 3T3-L1 adipocytes. Arch. Biochem. Biophys., 251, 738-746.
-
(1986)
Arch. Biochem. Biophys.
, vol.251
, pp. 738-746
-
-
Price, S.R.1
Olivecrona, T.2
Pekala, P.H.3
-
19
-
-
0026032419
-
The metabolic effects of tumor necrosis factor and other cytokines
-
Grunfeld, C. and Feingold, K.R. (1991) The metabolic effects of tumor necrosis factor and other cytokines. Biotherapy, 3, 143-158.
-
(1991)
Biotherapy
, vol.3
, pp. 143-158
-
-
Grunfeld, C.1
Feingold, K.R.2
-
21
-
-
0141835015
-
Insulin resistance, inflammation, and the prediabetic state
-
S.M. (2003) Insulin resistance, inflammation, and the prediabetic state. Am. J. Cardiol., 92, 18J-26J.
-
(2003)
Am. J. Cardiol.
, vol.92
-
-
-
22
-
-
77955362775
-
Chronic inflammation in obesity and the metabolic syndrome
-
[Epub ahead of print]
-
Monteiro, R. and Azevedo, I. (2010) Chronic inflammation in obesity and the metabolic syndrome. Mediators Inflamm., [Epub ahead of print].
-
(2010)
Mediators Inflamm
-
-
Monteiro, R.1
Azevedo, I.2
-
23
-
-
70350539525
-
FoxO1 links insulin resistance to proinflammatory cytokine IL-1β production in macrophages
-
Su, D.; Coudriet, G.M.; Hyun Kim, D.; Lu, Y.; Perdomo, G.; Qu, S.; Slusher, S.; Tse, H.M.; Piganelli, J.; Giannoukakis, N.; Zhang, J. and Dong, H. (2009) FoxO1 links insulin resistance to proinflammatory cytokine IL-1β production in macrophages. Diabetes, 58, 2624-2633.
-
(2009)
Diabetes
, vol.58
, pp. 2624-2633
-
-
Su, D.1
Coudriet, G.M.2
Hyun Kim, D.3
Lu, Y.4
Perdomo, G.5
Qu, S.6
Slusher, S.7
Tse, H.M.8
Piganelli, J.9
Giannoukakis, N.10
Zhang, J.11
Dong, H.12
-
24
-
-
4644338458
-
Circulating mononuclear cells in the obese are in a proinflammatory state
-
Ghanim, H.; Aljada, A.; Hofmeyer, D.; Syed, T.; Mohanty, P. and Dandona, P. (2004) Circulating mononuclear cells in the obese are in a proinflammatory state. Circulation, 110, 1564-1571.
-
(2004)
Circulation
, vol.110
, pp. 1564-1571
-
-
Ghanim, H.1
Aljada, A.2
Hofmeyer, D.3
Syed, T.4
Mohanty, P.5
Dandona, P.6
-
25
-
-
0032943709
-
C-reactive protein in healthy subjects: Associations with obesity, insulin resistance, and endothelial dysfunction: A potential role for cytokines originating from adipose tissue?
-
Yudkin, J.S.; Stehouwer, C.D.; Emeis, J.J. and Coppack, S.W. (1999) C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue? Arterioscler. Thromb. Vasc. Biol., 19, 972-978.
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 972-978
-
-
Yudkin, J.S.1
Stehouwer, C.D.2
Emeis, J.J.3
Coppack, S.W.4
-
26
-
-
0030735542
-
Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-α, in vivo
-
Mohamed-Ali, V.; Goodrick, S.; Rawesh, A.; Katz D.R.; Miles, J.M.; Yudkin, J.S.; Klein, S. and Coppack, S.W. (1997) Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-α, in vivo. J. Clin. Endocrinol. Metab., 82, 4196-4200.
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 4196-4200
-
-
Mohamed-Ali, V.1
Goodrick, S.2
Rawesh, A.3
Katz, D.R.4
Miles, J.M.5
Yudkin, J.S.6
Klein, S.7
Coppack, S.W.8
-
27
-
-
0030066399
-
Elaboration of type-1 plasminogen activator inhibitor from adipocytes: A potential pathogenetic link between obesity and cardiovascular disease
-
Lundgren, C.H.; Brown, S.L.; Nordt, T.K.; Sobel, B.E. and Fujii, S. (1996) Elaboration of type-1 plasminogen activator inhibitor from adipocytes: a potential pathogenetic link between obesity and cardiovascular disease. Circulation, 93, 106-110.
-
(1996)
Circulation
, vol.93
, pp. 106-110
-
-
Lundgren, C.H.1
Brown, S.L.2
Nordt, T.K.3
Sobel, B.E.4
Fujii, S.5
-
28
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg, S.P.; McCann, D.; Desai, M.; Rosenbaum, M.; Leibel, R.L. and Ferrante, A.W. Jr. (2003) Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest., 112, 1796-1808.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante Jr., A.W.6
-
29
-
-
72449191699
-
Adipose tissue as an endocrine organ
-
Galic, S.; Oakhill, J.S. and Steinberg, G.R. (2010) Adipose tissue as an endocrine organ. Mol. Cell. Endocrinol., 316, 129-139.
-
(2010)
Mol. Cell. Endocrinol.
, vol.316
, pp. 129-139
-
-
Galic, S.1
Oakhill, J.S.2
Steinberg, G.R.3
-
31
-
-
77953509678
-
Adipose tissue, inflammation and atherosclerosis
-
Gustafson, B. (2010) Adipose tissue, inflammation and atherosclerosis. J. Atheroscler. Thromb., 17, 332-341.
-
(2010)
J. Atheroscler. Thromb.
, vol.17
, pp. 332-341
-
-
Gustafson, B.1
-
32
-
-
39149143637
-
Adipokines: The missing link between insulin resistance and obesity
-
Antuna-Puente, B.; Feve, B.; Fellahi, S. and Bastard, J.P. (2008) Adipokines: the missing link between insulin resistance and obesity. Diabetes Metab., 34, 2-11.
-
(2008)
Diabetes Metab
, vol.34
, pp. 2-11
-
-
Antuna-Puente, B.1
Feve, B.2
Fellahi, S.3
Bastard, J.P.4
-
33
-
-
0034891684
-
Weight reduction increases plasma levels of an adipose-derived antiinflammatory protein, adiponectin
-
Yang, W.S.; Lee, W.J.; Funahashi, T.; Tanaka, S.; Matsuzawa, Y.; Chao, C.L.; Chen, C.L.; Tai, T.Y. and Chuang, L.M. (2001) Weight reduction increases plasma levels of an adipose-derived antiinflammatory protein, adiponectin. J. Clin. Endocrinol. Metab., 86, 3815-3819.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 3815-3819
-
-
Yang, W.S.1
Lee, W.J.2
Funahashi, T.3
Tanaka, S.4
Matsuzawa, Y.5
Chao, C.L.6
Chen, C.L.7
Tai, T.Y.8
Chuang, L.M.9
-
34
-
-
0033802857
-
Leptin stimulates uncoupling protein-2 mRNA expression and Krebs cycle activity and inhibits lipid synthesis in isolated rat white adipocytes
-
Ceddia, R.B.; William, W.N. Jr.; Lima, F.B.; Flandin, P.; Curi, R. and Giacobino, J.P. (2000) Leptin stimulates uncoupling protein-2 mRNA expression and Krebs cycle activity and inhibits lipid synthesis in isolated rat white adipocytes. Eur. J. Biochem., 267, 5952-5958.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 5952-5958
-
-
Ceddia, R.B.1
William Jr., W.N.2
Lima, F.B.3
Flandin, P.4
Curi, R.5
Giacobino, J.P.6
-
35
-
-
0030898516
-
Direct antidiabetic effect of leptin through triglyceride depletion of tissues
-
Shimabukuro, M.; Koyama, K.; Chen, G.; Wang, M.Y.; Trieu, F.; Lee, Y.; Newgard, C.B. and Unger, R.H. (1997) Direct antidiabetic effect of leptin through triglyceride depletion of tissues. Proc. Natl. Acad. Sci., 94, 4637-4641.
-
(1997)
Proc. Natl. Acad. Sci.
, vol.94
, pp. 4637-4641
-
-
Shimabukuro, M.1
Koyama, K.2
Chen, G.3
Wang, M.Y.4
Trieu, F.5
Lee, Y.6
Newgard, C.B.7
Unger, R.H.8
-
36
-
-
77949442621
-
TNF-α and obesity
-
Tzanavari, T.; Giannogonas, P. And Karalis, K.P. (2010) TNF-α and obesity. Curr. Dir. Autoimmun., 11, 145-156.
-
(2010)
Curr. Dir. Autoimmun.
, vol.11
, pp. 145-156
-
-
Tzanavari, T.1
Giannogonas, P.2
Karalis, K.P.3
-
37
-
-
0031892271
-
TNF-α and insulin resistance: Summary and future prospects
-
Peraldi, P. and Spiegelman, B. (1998) TNF-α and insulin resistance: summary and future prospects. Mol. Cell. Biochem., 182, 169-175.
-
(1998)
Mol. Cell. Biochem.
, vol.182
, pp. 169-175
-
-
Peraldi, P.1
Spiegelman, B.2
-
38
-
-
0033060675
-
Down regulation of peroxisome proliferator-activated receptor gamma expression by inflammatory cytokines and its reversal by thiazolidinediones
-
Tanaka, T.; Itoh, H.; Doi, K.; Fukunaga, Y.; Hosoda, K.; Shintani, M.; Yamashita, J.; Chun, T.H.; Inoue, M.; Masatsugu, K.; Sawada, N.; Saito, T.; Inoue, G.; Nishimura, H.; Yoshimasa, Y. and Nakao, K. (1999) Down regulation of peroxisome proliferator-activated receptor gamma expression by inflammatory cytokines and its reversal by thiazolidinediones. Diabetologia, 42, 702-710.
-
(1999)
Diabetologia
, vol.42
, pp. 702-710
-
-
Tanaka, T.1
Itoh, H.2
Doi, K.3
Fukunaga, Y.4
Hosoda, K.5
Shintani, M.6
Yamashita, J.7
Chun, T.H.8
Inoue, M.9
Masatsugu, K.10
Sawada, N.11
Saito, T.12
Inoue, G.13
Nishimura, H.14
Yoshimasa, Y.15
Nakao, K.16
-
39
-
-
33847280286
-
T-cell accumulation and regulated on activation, normal T cell expressed and secreted upregulation in adipose tissue in obesity
-
Wu, H.; Ghosh, S.; Perrard, X.D.; Feng, L.; Garcia, G.E.; Perrard, J.L.; Sweeney, J.F.; Peterson, L.E.; Chan, L.; Smith, C.W. and Ballantyne, C.M. (2007) T-cell accumulation and regulated on activation, normal T cell expressed and secreted upregulation in adipose tissue in obesity. Circulation, 115, 1029-1038.
-
(2007)
Circulation
, vol.115
, pp. 1029-1038
-
-
Wu, H.1
Ghosh, S.2
Perrard, X.D.3
Feng, L.4
Garcia, G.E.5
Perrard, J.L.6
Sweeney, J.F.7
Peterson, L.E.8
Chan, L.9
Smith, C.W.10
Ballantyne, C.M.11
-
40
-
-
0034918334
-
RANTES: A versatile and controversial chemokine
-
Appay, V. and Rowland-Jones, S.L. (2001) RANTES: a versatile and controversial chemokine. Trends Immunol., 22, 83-87.
-
(2001)
Trends Immunol
, vol.22
, pp. 83-87
-
-
Appay, V.1
Rowland-Jones, S.L.2
-
41
-
-
73849125378
-
CCL5 promotes macrophage recruitment and survival in human adipose tissue
-
Keophiphath, M.; Rouault, C.; Divoux, A.; Clément, K. and Lacasa, D. (2010) CCL5 promotes macrophage recruitment and survival in human adipose tissue. Arterioscler. Thromb. Vasc. Biol., 30, 39-45.
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 39-45
-
-
Keophiphath, M.1
Rouault, C.2
Divoux, A.3
Clément, K.4
Lacasa, D.5
-
42
-
-
0030065879
-
CC chemokines induce the generation of killer cells from CD56+ cells
-
Maghazachi, A.A.; Al-Aoukaty, A. and Schall, T.J. (1996) CC chemokines induce the generation of killer cells from CD56+ cells. Eur. J. Immunol., 26, 315-319.
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 315-319
-
-
Maghazachi, A.A.1
Al-Aoukaty, A.2
Schall, T.J.3
-
43
-
-
77951178397
-
Inducible nitric oxide synthase induction underlies lipid-induced hepatic insulin resistance in mice: Potential role of tyrosine nitration of insulin signaling proteins
-
Charbonneau, A. and Marette, A. (2010) Inducible nitric oxide synthase induction underlies lipid-induced hepatic insulin resistance in mice: potential role of tyrosine nitration of insulin signaling proteins. Diabetes, 59, 861-871.
-
(2010)
Diabetes
, vol.59
, pp. 861-871
-
-
Charbonneau, A.1
Marette, A.2
-
44
-
-
15944384240
-
Inducible nitric oxide synthase has divergent effects on vascular and metabolic function in obesity
-
Noronha, B.T.; Li, J.M.; Wheatcroft, S.B.; Shah, A.M. and Kearney, M.T. (2005) Inducible nitric oxide synthase has divergent effects on vascular and metabolic function in obesity. Diabetes, 54, 1082-1089.
-
(2005)
Diabetes
, vol.54
, pp. 1082-1089
-
-
Noronha, B.T.1
Li, J.M.2
Wheatcroft, S.B.3
Shah, A.M.4
Kearney, M.T.5
-
45
-
-
0034254655
-
FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family
-
Holcomb, I.N.; Kabakoff, R.C.; Chan, B.; Baker, T.W.; Gurney, A.; Henzel, W.; Nelson, C.; Lowman, H.B.; Wright, B.D.; Skelton, N.J.; Frantz G.D.; Tumas, D.B.; Peale, F.V. Jr.; Shelton, D.L. and Hébert, C.C. (2000) FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family. EMBO J., 19, 4046-4055.
-
(2000)
EMBO J
, vol.19
, pp. 4046-4055
-
-
Holcomb, I.N.1
Kabakoff, R.C.2
Chan, B.3
Baker, T.W.4
Gurney, A.5
Henzel, W.6
Nelson, C.7
Lowman, H.B.8
Wright, B.D.9
Skelton, N.J.10
Frantz, G.D.11
Tumas, D.B.12
Peale Jr., F.V.13
Shelton, D.L.14
Hébert, C.C.15
-
46
-
-
0037686319
-
Identification of RELMγ, a novel resistin-like molecule with a distinct expression pattern
-
Gerstmayer, B.; Küsters, D.; Gebel, S.; Müller, T.; Van Miert, E.; Hofmann, K. and Bosio, A. (2003) Identification of RELMγ, a novel resistin-like molecule with a distinct expression pattern. Genomics, 81, 588-595.
-
(2003)
Genomics
, vol.81
, pp. 588-595
-
-
Gerstmayer, B.1
Küsters, D.2
Gebel, S.3
Müller, T.4
van Miert, E.5
Hofmann, K.6
Bosio, A.7
-
47
-
-
63849103057
-
Role of resistin in insulin sensitivity in rodents and humans
-
Barnes, K.M. and Miner, J.L. (2009) Role of resistin in insulin sensitivity in rodents and humans. Curr. Protein Pept. Sci., 10, 96-107.
-
(2009)
Curr. Protein Pept. Sci.
, vol.10
, pp. 96-107
-
-
Barnes, K.M.1
Miner, J.L.2
-
48
-
-
10744220840
-
Plasma resistin concentrations measured by enzyme-linked immunosorbent assay using a newly developed monoclonal antibody are elevated in individuals with type 2 diabetes mellitus
-
Youn, B.S.; Yu, K.Y.; Park, H.J.; Lee, N.S.; Min, S.S.; Youn, M.Y.; Cho, Y.M.; Park, Y.J.; Kim, S.Y.; Lee, H.K. and Park, K.S. (2004) Plasma resistin concentrations measured by enzyme-linked immunosorbent assay using a newly developed monoclonal antibody are elevated in individuals with type 2 diabetes mellitus. J. Clin. Endocrinol. Metab., 89, 150-156.
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 150-156
-
-
Youn, B.S.1
Yu, K.Y.2
Park, H.J.3
Lee, N.S.4
Min, S.S.5
Youn, M.Y.6
Cho, Y.M.7
Park, Y.J.8
Kim, S.Y.9
Lee, H.K.10
Park, K.S.11
-
49
-
-
78650006092
-
Correlation of plasma resistin with obesity and insulin resistance in type 2 diabetic patients
-
[Epub ahead of print]
-
Gharibeh, M.Y.; Al Tawallbeh, G.M.; Abboud, M.M.; Radaideh, A.; Alhader, A.A. and Khabour, O.F. (2010) Correlation of plasma resistin with obesity and insulin resistance in type 2 diabetic patients. Diabetes Metab., [Epub ahead of print].
-
(2010)
Diabetes Metab
-
-
Gharibeh, M.Y.1
Al Tawallbeh, G.M.2
Abboud, M.M.3
Radaideh, A.4
Alhader, A.A.5
Khabour, O.F.6
-
50
-
-
2042438401
-
Changes in glycemia by leptin administration or high- fat feeding in rodent models of obe sity/type 2 diabetes suggest a link between resistin expression and control of glucose homeostasis
-
Asensio, C.; Cettour-Rose, P.; Theander-Carrillo, C.; Rohner-Jeanrenaud, F. and Muzzin P. (2004) Changes in glycemia by leptin administration or high- fat feeding in rodent models of obe sity/type 2 diabetes suggest a link between resistin expression and control of glucose homeostasis. Endocrinology, 145, 2206-2213.
-
(2004)
Endocrinology
, vol.145
, pp. 2206-2213
-
-
Asensio, C.1
Cettour-Rose, P.2
Theander-Carrillo, C.3
Rohner-Jeanrenaud, F.4
Muzzin, P.5
-
51
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu, H.; Barnes, G.T.; Yang, Q.; Tan, G.; Yang, D.; Chou, C.J.; Sole, J.; Nichols, A.; Ross, J.S.; Tartaglia, L.A. and Chen, H. (2003) Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest., 112, 1821-1830.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
52
-
-
0032587240
-
The role of TNFα and TNF receptors in obesity and insulin resistance
-
Hotamisligil, G.S. (1999) The role of TNFα and TNF receptors in obesity and insulin resistance. J. Intern. Med., 245, 621-625.
-
(1999)
J. Intern. Med.
, vol.245
, pp. 621-625
-
-
Hotamisligil, G.S.1
-
53
-
-
23044439100
-
Human resistin stimulates the proinflammatory cytokines TNF-α and IL-12 in macrophages by NF-κB-dependent pathway
-
Silswal, N.; Singh, A.K.; Aruna, B.; Mukhopadhyay, S.; Ghosh, S. and Ehtesham, N.Z. (2005) Human resistin stimulates the proinflammatory cytokines TNF-α and IL-12 in macrophages by NF-κB-dependent pathway. Biochem. Biophys. Res. Commun., 334, 1092-1101.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.334
, pp. 1092-1101
-
-
Silswal, N.1
Singh, A.K.2
Aruna, B.3
Mukhopadhyay, S.4
Ghosh, S.5
Ehtesham, N.Z.6
-
54
-
-
0037434632
-
The genomic organization of mouse resistin reveals major differences from the human resistin: Functional implications
-
Ghosh, S.; Singh, A.K.; Aruna, B.; Mukhopadhyay, S. and Ehtesham, N.Z. (2003) The genomic organization of mouse resistin reveals major differences from the human resistin: functional implications. Gene, 305, 27-34.
-
(2003)
Gene
, vol.305
, pp. 27-34
-
-
Ghosh, S.1
Singh, A.K.2
Aruna, B.3
Mukhopadhyay, S.4
Ehtesham, N.Z.5
-
55
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
Lumeng, C.N.; Bodzin, J.L. and Saltiel, A.R. (2007) Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J. Clin. Invest., 117, 175-184
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
56
-
-
77954189887
-
Eating ourselves to death (and despair): The contribution of adiposity and inflammation to depression
-
Shelton, R.C. and Miller, A.H. (2010) Eating ourselves to death (and despair): the contribution of adiposity and inflammation to depression. Prog. Neurobiol., 91, 275-299.
-
(2010)
Prog. Neurobiol.
, vol.91
, pp. 275-299
-
-
Shelton, R.C.1
Miller, A.H.2
-
57
-
-
6944237757
-
Adipokines: Inflammation and the pleiotropic role of white adipose tissue
-
Trayhurn, P. and Wood, I.S. (2004) Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br. J. Nutr., 92, 347-355.
-
(2004)
Br. J. Nutr.
, vol.92
, pp. 347-355
-
-
Trayhurn, P.1
Wood, I.S.2
-
58
-
-
0042166015
-
Integrative physiology of human adipose tissue
-
Frayn, K.N.; Karpe, F.; Fielding, B.A.; Macdonald, I.A. and Coppack, S.W. (2003) Integrative physiology of human adipose tissue. Int. J. Obes. Relat. Metab. Disord., 27, 875-888.
-
(2003)
Int. J. Obes. Relat. Metab. Disord.
, vol.27
, pp. 875-888
-
-
Frayn, K.N.1
Karpe, F.2
Fielding, B.A.3
Macdonald, I.A.4
Coppack, S.W.5
-
59
-
-
77958508121
-
Adipose tissue-specific inhibition of hypoxia inducible factor 1α induces obesity and glucose intolerance by impeding energy expenditure in mice
-
[Epub ahead of print]
-
Zhang, X.; Lam, K.S.; Ye, H.; Chung, S.K.; Zhou, M.; Wang, Y. and Xu, A. (2010) Adipose tissue-specific inhibition of hypoxia inducible factor 1α induces obesity and glucose intolerance by impeding energy expenditure in mice. J. Biol. Chem., [Epub ahead of print].
-
(2010)
J. Biol. Chem.
-
-
Zhang, X.1
Lam, K.S.2
Ye, H.3
Chung, S.K.4
Zhou, M.5
Wang, Y.6
Xu, A.7
-
60
-
-
0035313697
-
HIF-1 and mechanisms of hypoxia sensing
-
Semenza, G.L. (2001) HIF-1 and mechanisms of hypoxia sensing, Curr. Opin. Cell Biol., 13, 167-171.
-
(2001)
Curr. Opin. Cell Biol.
, vol.13
, pp. 167-171
-
-
Semenza, G.L.1
-
61
-
-
0142057126
-
Effects of hypoxia on the expression of proangiogenic factors in differentiated 3T3-F442A adipocytes
-
Lolmède, K.; Durand de Saint Front, V.; Galitzky, J.; Lafontan, M. and Bouloumié, A. (2003) Effects of hypoxia on the expression of proangiogenic factors in differentiated 3T3-F442A adipocytes. Int. J. Obes. Relat. Metab. Disord., 27, 1187-1195.
-
(2003)
Int. J. Obes. Relat. Metab. Disord.
, vol.27
, pp. 1187-1195
-
-
Lolmède, K.1
de Saint Front, D.V.2
Galitzky, J.3
Lafontan, M.4
Bouloumié, A.5
-
62
-
-
58149500277
-
Emerging role of adipose tissue hypoxia in obesity and insulin resistance
-
Ye, J. (2009) Emerging role of adipose tissue hypoxia in obesity and insulin resistance. Int. J. Obes., 33, 54-66.
-
(2009)
Int. J. Obes.
, vol.33
, pp. 54-66
-
-
Ye, J.1
-
63
-
-
77955806634
-
JNK1 and IKKbeta: Molecular links between obesity and metabolic dysfunction
-
Solinas, G. and Karin, M. (2010) JNK1 and IKKbeta: molecular links between obesity and metabolic dysfunction. FASEB J., 24, 2596-2611.
-
(2010)
FASEB J
, vol.24
, pp. 2596-2611
-
-
Solinas, G.1
Karin, M.2
-
64
-
-
33750153292
-
Attenuation of leptin and insulin signalling by SOCS proteins
-
Howard, J.K. and Flier, J.S. (2006) Attenuation of leptin and insulin signalling by SOCS proteins. Trends Endocrinol. Metab., 17, 365-371.
-
(2006)
Trends Endocrinol. Metab.
, vol.17
, pp. 365-371
-
-
Howard, J.K.1
Flier, J.S.2
-
65
-
-
72249106180
-
Increase in plasma endotoxin concentrations and the expression of Toll-like receptors and suppressor of cytokine signalling-3 in mononuclear cells after a high-fat, high-carbohydrate meal: Implications for insulin resistance
-
Ghanim, H.; Abuaysheh, S.; Sia, C.L.; Korzeniewski, K.; Chaudhuri, A.; Fernandez-Real J.M. and Dandona, P. (2009) Increase in plasma endotoxin concentrations and the expression of Toll-like receptors and suppressor of cytokine signalling-3 in mononuclear cells after a high-fat, high-carbohydrate meal: implications for insulin resistance. Diabetes Care, 32, 2281-2287.
-
(2009)
Diabetes Care
, vol.32
, pp. 2281-2287
-
-
Ghanim, H.1
Abuaysheh, S.2
Sia, C.L.3
Korzeniewski, K.4
Chaudhuri, A.5
Fernandez-Real, J.M.6
Dandona, P.7
-
66
-
-
0036830636
-
SOCS-1 and SOCS-3 block insulin signalling by ubiquitinmediated degradation of IRS1 and IRS2
-
Rui, L.; Yuan, M.; Frantz, D.; Shoelson, S. and White, M.F. (2002) SOCS-1 and SOCS-3 block insulin signalling by ubiquitinmediated degradation of IRS1 and IRS2. J. Biol. Chem., 277, 42394-42398.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42394-42398
-
-
Rui, L.1
Yuan, M.2
Frantz, D.3
Shoelson, S.4
White, M.F.5
-
67
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan, U.; Cao, Q.; Yilmaz, E.; Lee, A.H.; Iwakoshi, N.N.; Ozdelen, E.; Tuncman, G.; Görgün, C.; Glimcher, L.H. and Hotamisligil, G.S. (2004) Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science, 306, 457-461.
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Ozdelen, E.6
Tuncman, G.7
Görgün, C.8
Glimcher, L.H.9
Hotamisligil, G.S.10
-
68
-
-
77950343252
-
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
-
Hotamisligil, G.S. (2010) Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell, 140, 900-917.
-
(2010)
Cell
, vol.140
, pp. 900-917
-
-
Hotamisligil, G.S.1
-
69
-
-
77954218373
-
Lipopolysaccharide, high glucose and saturated fatty acids induce endoplasmic reticulum stress in cultured primary human adipocytes: Salicylate alleviates this stress
-
Alhusaini, S.; McGee, K.; Schisano, B.; Harte, A.; McTernan, P.; Kumar, S. and Tripathi, G. (2010) Lipopolysaccharide, high glucose and saturated fatty acids induce endoplasmic reticulum stress in cultured primary human adipocytes: Salicylate alleviates this stress. Biochem. Biophys. Res. Commun., 397, 472-478.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.397
, pp. 472-478
-
-
Alhusaini, S.1
McGee, K.2
Schisano, B.3
Harte, A.4
McTernan, P.5
Kumar, S.6
Tripathi, G.7
-
70
-
-
33644886769
-
Nutrients suppress phosphatidylinositol 3-kinase/Akt signalling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation
-
Tzatsos, A. and Kandror K.V. (2006) Nutrients suppress phosphatidylinositol 3-kinase/Akt signalling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation. Mol. Cell. Biol., 26, 63-76.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 63-76
-
-
Tzatsos, A.1
Kandror, K.V.2
-
71
-
-
20844451550
-
Modulation of insulin action by dietary proteins and amino acids: Role of the mammalian target of rapamycin nutrient sensing pathway
-
Tremblay, F.; Jacques, H. and Marette, A. (2005) Modulation of insulin action by dietary proteins and amino acids: role of the mammalian target of rapamycin nutrient sensing pathway. Curr. Opin. Clin. Nutr. Metab. Care, 8, 457-462.
-
(2005)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.8
, pp. 457-462
-
-
Tremblay, F.1
Jacques, H.2
Marette, A.3
-
72
-
-
14244252683
-
Activation of the mammalian target of rapamycin pathway acutely inhibitsinsulin signalling to Akt and glucose transport in 3T3-L1 and human adipocytes
-
Tremblay, F.; Gagnon, A.; Veilleux, A.; Sorisky, A. and Marette, A. (2005) Activation of the mammalian target of rapamycin pathway acutely inhibitsinsulin signalling to Akt and glucose transport in 3T3-L1 and human adipocytes. Endocrinology, 146, 1328-1337.
-
(2005)
Endocrinology
, vol.146
, pp. 1328-1337
-
-
Tremblay, F.1
Gagnon, A.2
Veilleux, A.3
Sorisky, A.4
Marette, A.5
-
73
-
-
33744505375
-
Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1
-
Um, S.H.; D'Alessio, D. and Thomas, G. (2006) Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1. Cell Metab., 3, 393-402.
-
(2006)
Cell Metab
, vol.3
, pp. 393-402
-
-
Um, S.H.1
D'Alessio, D.2
Thomas, G.3
-
74
-
-
77954251401
-
Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetes
-
Ost, A.; Svensson, K.; Ruishalme, I.; Brännmark, C.; Franck, N.; Krook, H.; Sandström, P.; Kjolhede, P. and Strålfors, P. (2010) Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetes. Mol. Med., 16, 235-246.
-
(2010)
Mol. Med.
, vol.16
, pp. 235-246
-
-
Ost, A.1
Svensson, K.2
Ruishalme, I.3
Brännmark, C.4
Franck, N.5
Krook, H.6
Sandström, P.7
Kjolhede, P.8
Strålfors, P.9
-
75
-
-
33846330586
-
Potentiation of insulinstimulated glucose transport by the AMP-activated protein kinase
-
Ju, J.S.; Gitcho, M.A.; Casmaer, C.A.; Patil, P.B.; Han, D.G.; Spencer, S.A. and Fisher, J.S. (2007) Potentiation of insulinstimulated glucose transport by the AMP-activated protein kinase. Am. J. Physiol. Cell Physiol., 292, C564-C572.
-
(2007)
Am. J. Physiol. Cell Physiol.
, vol.292
-
-
Ju, J.S.1
Gitcho, M.A.2
Casmaer, C.A.3
Patil, P.B.4
Han, D.G.5
Spencer, S.A.6
Fisher, J.S.7
-
76
-
-
0347318052
-
The AMP-activated protein kinase cascade--a unifying system for energy control
-
Carling, D. (2004) The AMP-activated protein kinase cascade--a unifying system for energy control. Trends Biochem. Sci., 29, 18-24.
-
(2004)
Trends Biochem. Sci.
, vol.29
, pp. 18-24
-
-
Carling, D.1
-
77
-
-
2442713803
-
Inhibition of inducible nitric-oxide synthase by activators of AMP-activated protein kinase: A new mechanism of action of insulin-sensitizing drugs
-
Pilon, G.; Dallaire, P. and Marette A. (2004) Inhibition of inducible nitric-oxide synthase by activators of AMP-activated protein kinase: a new mechanism of action of insulin-sensitizing drugs. J. Biol. Chem., 279, 20767-20774.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20767-20774
-
-
Pilon, G.1
Dallaire, P.2
Marette, A.3
-
78
-
-
63649097100
-
CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance
-
Chavey, C.; Lazennec, G.; Lagarrigue, S.; Clapé C.; Iankova, I.; Teyssier, J.; Annicotte, J.S.; Schmidt, J; Mataki, C.; Yamamoto, H.; Sanches, R.; Guma, A.; Stich, V.; Vitkova, M.; Jardin-Watelet, B.; Renard, E.; Strieter, R.; Tuthill, A.; Hotamisligil, G.S.; Vidal-Puig, A.; Zorzano, A.; Langin, D. and Fajas, L. (2009) CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance. Cell Metab., 9, 339-349.
-
(2009)
Cell Metab
, vol.9
, pp. 339-349
-
-
Chavey, C.1
Lazennec, G.2
Lagarrigue, S.3
Clapé, C.4
Iankova, I.5
Teyssier, J.6
Annicotte, J.S.7
Schmidt, J.8
Mataki, C.9
Yamamoto, H.10
Sanches, R.11
Guma, A.12
Stich, V.13
Vitkova, M.14
Jardin-Watelet, B.15
Renard, E.16
Strieter, R.17
Tuthill, A.18
Hotamisligil, G.S.19
Vidal-Puig, A.20
Zorzano, A.21
Langin, D.22
Fajas, L.23
more..
-
79
-
-
77955752307
-
CXCL5 drives obesity to diabetes, and further
-
Chavey, C. and Fajas, L. (2009) CXCL5 drives obesity to diabetes, and further. Aging (Albany NY). 1, 674-677.
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 674-677
-
-
Chavey, C.1
Fajas, L.2
-
80
-
-
28944446431
-
The many faces of PPARγ
-
Lehrke, M. and Lazar, M.A. (2005) The many faces of PPARγ. Cell, 123, 993-999.
-
(2005)
Cell
, vol.123
, pp. 993-999
-
-
Lehrke, M.1
Lazar, M.A.2
-
81
-
-
77954941113
-
Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5
-
Choi, J.H.; Banks, A.S.; Estall, J.L.; Kajimura, S.; Boström, P.; Laznik, D.; Ruas, J.L.; Chalmers, M.J.; Kamenecka, T.M.; Blüher, M; Griffin, P.R. and Spiegelman, B.M. (2010) Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5. Nature, 466, 451-456.
-
(2010)
Nature
, vol.466
, pp. 451-456
-
-
Choi, J.H.1
Banks, A.S.2
Estall, J.L.3
Kajimura, S.4
Boström, P.5
Laznik, D.6
Ruas, J.L.7
Chalmers, M.J.8
Kamenecka, T.M.9
Blüher, M.10
Griffin, P.R.11
Spiegelman, B.M.12
-
82
-
-
77955274518
-
PPARγ in adipocyte differentiation and metabolism--novel insights from genome-wide studies
-
Siersbaek, R.; Nielsen, R. and Mandrup, S. (2010) PPARγ in adipocyte differentiation and metabolism--novel insights from genome-wide studies. FEBS Lett., 584, 3242-3249.
-
(2010)
FEBS Lett
, vol.584
, pp. 3242-3249
-
-
Siersbaek, R.1
Nielsen, R.2
Mandrup, S.3
-
83
-
-
0141446024
-
Liver peroxisome proliferator-activated receptorγ contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass
-
Gavrilova, O.; Haluzik, M.; Matsusue, K.; Cutson, J.J.; Johnson, L.; Dietz, K.R.; Nicol, C.J.; Vinson, C.; Gonzalez, F.J. and Reitman, M.L. (2003) Liver peroxisome proliferator-activated receptorγ contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass. J. Biol. Chem., 278, 34268-34276.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 34268-34276
-
-
Gavrilova, O.1
Haluzik, M.2
Matsusue, K.3
Cutson, J.J.4
Johnson, L.5
Dietz, K.R.6
Nicol, C.J.7
Vinson, C.8
Gonzalez, F.J.9
Reitman, M.L.10
-
84
-
-
77954672503
-
Adipose tissue macrophages: Their role in adipose tissue remodeling
-
Suganami, T. and Ogawa, Y. (2010) Adipose tissue macrophages: their role in adipose tissue remodeling. J. Leukoc. Biol., 88, 33-39.
-
(2010)
J. Leukoc. Biol.
, vol.88
, pp. 33-39
-
-
Suganami, T.1
Ogawa, Y.2
-
85
-
-
77956395533
-
The role of adipose tissue and lipotoxicity in the pathogenesis of type 2 diabetes
-
Cusi, K. (2010) The role of adipose tissue and lipotoxicity in the pathogenesis of type 2 diabetes. Curr. Diab. Rep., 10, 306-315.
-
(2010)
Curr. Diab. Rep.
, vol.10
, pp. 306-315
-
-
Cusi, K.1
-
86
-
-
85036710969
-
A non-TZD PPARα/γ dual agonist CG301360 alleviates insulin resistance and lipid dysregulation in db/db mice
-
[Epub ahead of print]
-
Jeong, H.W.; Lee, J.W.; Kim, W.S.; Choe, S.S.; Shin, H.J.; Lee, G.Y.; Shin, D.; Lee, J.H.; Choi, E.B.; Lee, H.K.; Yon, G.H.; Cho, B.; Kim, H.R.; Choi, S.H.; Chung, Y.S.; Park, S.B.; Chung, H.; Ro, S. and Kim, J.B. (2010) A non-TZD PPARα/γ dual agonist CG301360 alleviates insulin resistance and lipid dysregulation in db/db mice. Mol. Pharmacol., [Epub ahead of print].
-
(2010)
Mol. Pharmacol.
-
-
Jeong, H.W.1
Lee, J.W.2
Kim, W.S.3
Choe, S.S.4
Shin, H.J.5
Lee, G.Y.6
Shin, D.7
Lee, J.H.8
Choi, E.B.9
Lee, H.K.10
Yon, G.H.11
Cho, B.12
Kim, H.R.13
Choi, S.H.14
Chung, Y.S.15
Park, S.B.16
Chung, H.17
Ro, S.18
Kim, J.B.19
-
87
-
-
0031886864
-
The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
-
Ricote, M.; Li, A.C.; Willson, T.M.; Kelly, C.J. and Glass, C.K. (1998) The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature, 391, 79-82.
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
88
-
-
26444471700
-
A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ
-
Pascual, G.; Fong, A.L.; Ogawa, S.; Gamliel, A.; Li, A.C.; Perissi, V.; Rose, D.W.; Willson, T.M.; Rosenfeld, M.G. and Glass, C.K. (2005) A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ. Nature, 437, 759-763.
-
(2005)
Nature
, vol.437
, pp. 759-763
-
-
Pascual, G.1
Fong, A.L.2
Ogawa, S.3
Gamliel, A.4
Li, A.C.5
Perissi, V.6
Rose, D.W.7
Willson, T.M.8
Rosenfeld, M.G.9
Glass, C.K.10
-
89
-
-
0038660699
-
Preadipocyte conversion to macrophage. Evidence of plasticity
-
Charrière, G.; Cousin, B.; Arnaud, E.; André, M.; Bacou, F.; Penicaud, L. and Casteilla, L. (2003) Preadipocyte conversion to macrophage. Evidence of plasticity. J. Biol. Chem., 278, 9850-9855.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9850-9855
-
-
Charrière, G.1
Cousin, B.2
Arnaud, E.3
André, M.4
Bacou, F.5
Penicaud, L.6
Casteilla, L.7
-
90
-
-
85036703441
-
-
University of Virginia study shows that Lisofylline reduces obesity-related inflammation and insulin resistance, (Accessed September 25)
-
University of Virginia study shows that Lisofylline reduces obesity-related inflammation and insulin resistance. http://www.drugs.com/clinical_trials/university-virginia-study-shows-lisofyllinereduces-obesity-related-inflammation-insulin-resistance-3977.html (Accessed September 25, 2010)
-
(2010)
-
-
-
91
-
-
68349150756
-
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
-
Nishimura, S.; Manabe, I.; Nagasaki, M.; Eto, K.; Yamashita, H.; Ohsugi, M.; Otsu, M.; Hara, K.; Ueki, K.; Sugiura, S.; Yoshimura, K.; Kadowaki, T. and Nagai, R. (2009) CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat. Med., 15, 914-920.
-
(2009)
Nat. Med.
, vol.15
, pp. 914-920
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
Eto, K.4
Yamashita, H.5
Ohsugi, M.6
Otsu, M.7
Hara, K.8
Ueki, K.9
Sugiura, S.10
Yoshimura, K.11
Kadowaki, T.12
Nagai, R.13
-
92
-
-
68349137821
-
Normalization of obesity-associated insulin resistance through immunotherapy
-
Winer, S.; Chan, Y.; Paltser, G.; Truong, D.; Tsui, H.; Bahrami, J.; Dorfman, R.; Wang, Y.; Zielenski, J.; Mastronardi, F.; Maezawa, Y.; Drucker, D.J.; Engleman, E.; Winer, D. and Dosch, H.M. (2009) Normalization of obesity-associated insulin resistance through immunotherapy. Nat. Med., 15, 921-929.
-
(2009)
Nat. Med.
, vol.15
, pp. 921-929
-
-
Winer, S.1
Chan, Y.2
Paltser, G.3
Truong, D.4
Tsui, H.5
Bahrami, J.6
Dorfman, R.7
Wang, Y.8
Zielenski, J.9
Mastronardi, F.10
Maezawa, Y.11
Drucker, D.J.12
Engleman, E.13
Winer, D.14
Dosch, H.M.15
-
93
-
-
38449090623
-
Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes
-
Tritt, M.; Sgouroudis, E.; d'Hennezel, E.; Albanese, A. and Piccirillo, C.A. (2008) Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes. Diabetes, 57, 113-123.
-
(2008)
Diabetes
, vol.57
, pp. 113-123
-
-
Tritt, M.1
Sgouroudis, E.2
D'Hennezel, E.3
Albanese, A.4
Piccirillo, C.A.5
-
94
-
-
77954230361
-
The PPE18 of Mycobacterium tuberculosis interacts with TLR2 and activates IL-10 induction in macrophage
-
Nair, S.; Ramaswamy, P.A.; Ghosh, S.; Joshi, D.C.; Pathak, N.; Siddiqui, I.; Sharma, P.; Hasnain, S.E.; Mande, S.C. and Mukhopadhyay, S. (2009) The PPE18 of Mycobacterium tuberculosis interacts with TLR2 and activates IL-10 induction in macrophage. J. Immunol., 183, 6269-6281.
-
(2009)
J. Immunol.
, vol.183
, pp. 6269-6281
-
-
Nair, S.1
Ramaswamy, P.A.2
Ghosh, S.3
Joshi, D.C.4
Pathak, N.5
Siddiqui, I.6
Sharma, P.7
Hasnain, S.E.8
Mande, S.C.9
Mukhopadhyay, S.10
-
95
-
-
77951888771
-
Glutathione-redox balance regulates crel- driven IL-12 production in macrophages: Possible implications in anti-tuberculosis immunotherapy
-
Alam, K.; Ghousunnissa, S.; Nair, S.; Valluri, V.L. and Mukhopadhyay, S. (2010) Glutathione-redox balance regulates crel- driven IL-12 production in macrophages: possible implications in anti-tuberculosis immunotherapy. J. Immunol., 184, 2918-2929.
-
(2010)
J. Immunol.
, vol.184
, pp. 2918-2929
-
-
Alam, K.1
Ghousunnissa, S.2
Nair, S.3
Valluri, V.L.4
Mukhopadhyay, S.5
-
96
-
-
33644766950
-
Oxidative stress in type 2 diabetes: The role of fasting and postprandial glycaemia
-
Wright, E. Jr.; Scism-Bacon, J.L. and Glass, L.C. (2006) Oxidative stress in type 2 diabetes: the role of fasting and postprandial glycaemia. Int. J. Clin. Pract., 60, 308-314.
-
(2006)
Int. J. Clin. Pract.
, vol.60
, pp. 308-314
-
-
Wright Jr., E.1
Scism-Bacon, J.L.2
Glass, L.C.3
-
97
-
-
77953307362
-
Oxidative stress, nitric oxide, and diabetes
-
Pitocco, D.; Zaccardi, F.; Di Stasio, E.; Romitelli, F.; Santini, S.A.; Zuppi, C. and Ghirlanda, G. (2010) Oxidative stress, nitric oxide, and diabetes. Rev. Diabet. Stud., 7, 15-25.
-
(2010)
Rev. Diabet. Stud.
, vol.7
, pp. 15-25
-
-
Pitocco, D.1
Zaccardi, F.2
Di Stasio, E.3
Romitelli, F.4
Santini, S.A.5
Zuppi, C.6
Ghirlanda, G.7
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