How obesity causes diabetes: Not a tall tale

Science

Volumn 307, Issue 5708, 2005, Pages 373-375

  Lazar, Mitchell A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDEMIOLOGY; FLAMMABILITY; GENES;

DIABETES; EVOLUTIONARY THEORIES; OBESITY;

DISEASES;

ACYLATION STIMULATING PROTEIN; ADIPOCYTOKINE; ADIPONECTIN; ADIPSIN; ANGIOTENSINOGEN; INTERLEUKIN 6; LEPTIN; MONOCYTE CHEMOTACTIC PROTEIN 1; OROSOMUCOID; PLASMINOGEN ACTIVATOR INHIBITOR 1; RESISTIN; SERUM AMYLOID A; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VISFATIN;

MEDICINE;

BODY FAT; DIABETES MELLITUS; ENERGY METABOLISM; EPIGENETICS; HUMAN; INSULIN RESISTANCE; LIFESTYLE; LIPID STORAGE; NONHUMAN; NUTRITION; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW;

ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; CYTOKINES; DIABETES MELLITUS, TYPE 2; EPIGENESIS, GENETIC; EVOLUTION; FETAL NUTRITION DISORDERS; GLUCOSE; HUMANS; IMMUNITY, NATURAL; INFLAMMATION; INSULIN; INSULIN RESISTANCE; LEPTIN; LIPID METABOLISM; MACROPHAGES; OBESITY; PHENOTYPE; PROTEINS;

EID: 12344266697     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1104342     Document Type: Review

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52. I thank R. Ahima, M. Birnbaum, M. Brown, A. Lazar, S. Mandel, and A. Rubenstein for critical comments on the manuscript and members of my laboratory for helpful discussions. I apologize that many relevant articles could not be cited because of space limitations. Supported by the National Institute of Diabetes, Digestive, and Kidney Diseases.