Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation

Journal of Experimental Medicine

Volumn 193, Issue 2, 2001, Pages 263-269

  Kawazoe, Yoshinori ^a   Naka, Tetsuji ^a   Fujimoto, Minoru ^a   Kohzaki, Hidetsugu ^a   Morita, Yoshiaki ^a   Narazaki, Masashi ^a   Okumura, Kohichi ^d   Saitoh, Hiroshi ^a   Nakagawa, Reiko ^a   Uchiyama, Yasuo ^a   Akira, Shizuo ^b   Kishimoto, Tadamitsu ^c  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d BIOMOL ENG RESEARCH INSTITUTE   (Japan)

Author keywords

Diabetes; Insulin; IRS 1; Janus kinase; SSI 1 SOCS1 signaling

Indexed keywords

CYTOKINE; INSULIN RECEPTOR SUBSTRATE 1; JANUS KINASE; STAT PROTEIN;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; BASE SEQUENCE; CARRIER PROTEINS; DNA PRIMERS; FEEDBACK; HYPOGLYCEMIA; INSULIN; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEINS; PHOSPHORYLATION; REPRESSOR PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 0035862334     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.193.2.263     Document Type: Article

References (24)

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