Molecular Determinants of Selective Agonist and Antagonist Binding to the Histamine H4 Receptor

Current Topics in Medicinal Chemistry

Volumn 11, Issue 6, 2011, Pages 661-679

  Istyastono, Enade P ^a   de Graaf, Chris ^a   de Esch, Iwan J P ^a   Leurs, Rob ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Receptor ligand interactions; Site directed mutations; Structure activity relationships

Indexed keywords

1 (5 CHLORO 2 INDOLYLCARBONYL) 4 METHYLPIPERAZINE; 1 [2 (AMIDINOTHIO)ETHYL]GUANIDINE; 4 METHYLHISTAMINE; BENZIMIDAZOLE DERIVATIVE; BENZODIAZEPINE DERIVATIVE; CLOBENPROPIT; CLOZAPINE; GUANIDINE DERIVATIVE; HISTAMINE; HISTAMINE AGONIST; HISTAMINE DERIVATIVE; HISTAMINE H1 RECEPTOR; HISTAMINE H2 RECEPTOR; HISTAMINE H3 RECEPTOR; HISTAMINE H4 RECEPTOR AGONIST; HISTAMINE H4 RECEPTOR ANTAGONIST; PIPERAZINE DERIVATIVE; PYRIMIDINE DERIVATIVE; QUINAZOLINE DERIVATIVE; QUINOXALINE DERIVATIVE; THIOPERAMIDE; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; HUMAN; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION; RECEPTOR BLOCKING; REVIEW; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

EID: 79952977834     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568026611109060661     Document Type: Review

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