Identification of 4-(1H-Imidazol-4(5)-ylmethyl)pyridine (Immethridine) as a Novel, Potent, and Highly Selective Histamine H3 Receptor Agonist

Journal of Medicinal Chemistry

Volumn 47, Issue 10, 2004, Pages 2414-2417

  Kitbunnadaj, Ruengwit ^a,b   Zuiderveld, Obbe P ^a   Christophe, Bernard ^c   Hulscher, Saskia ^a   Menge, Wiro M P B ^a   Gelens, Edith ^a   Snip, Erwin ^a   Bakker, Remko A ^a   Celanire, Sylvain ^c   Gillard, Michel ^c   Talaga, Patrice ^c   Timmerman, Henk ^a   Leurs, Rob ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b NARESUAN UNIVERSITY   (Thailand)

^c UCB PHARMA   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

HISTAMINE H3 RECEPTOR AGONIST; HISTAMINE H4 RECEPTOR; IMMEPIP; IMMETHRIDINE; PIPERIDINE DERIVATIVE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG IDENTIFICATION; DRUG RECEPTOR BINDING;

ANIMALS; CELL LINE; GUINEA PIGS; HISTAMINE AGONISTS; HUMANS; ILEUM; IMIDAZOLES; MUSCLE CONTRACTION; MUSCLE, SMOOTH; MYENTERIC PLEXUS; PYRIDINES; RADIOLIGAND ASSAY; RECEPTORS, HISTAMINE H3; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 2342470022     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049932u     Document Type: Article

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