Synthesis of (±)-trans- or cis-(5-aminomethyltetrahydrofuranyl) imidazole by Mitsunobu cyclization: Synthetic studies toward novel histamine H3 or H4-ligands

Chemical and Pharmaceutical Bulletin

Volumn 51, Issue 3, 2003, Pages 325-329

  Harusawa, Shinya ^a   Araki, Lisa ^a   Imazu, Tomonari ^a   Ohishi, Hirofumi ^a   Sakamoto, Yasuhiko ^b   Kurihara, Takushi ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b Azwell Inc   (Japan)

Author keywords

1,4 diol; Cyclization; H3; H4; Mitsunobu reaction

Indexed keywords

(5 AMINOMETHYLTETRAHYDROFURANYL)IMIDAZOLE; GLUTAMIC ACID; HISTAMINE H3 RECEPTOR; HISTAMINE H3 RECEPTOR AGONIST; HISTAMINE H4 RECEPTOR; IMIDAZOLE DERIVATIVE; LIGAND; UNCLASSIFIED DRUG; G PROTEIN COUPLED RECEPTOR; HISTAMINE AGONIST; HISTAMINE RECEPTOR; HRH4 PROTEIN, HUMAN;

ARTICLE; CYCLIZATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; LIGAND BINDING; MITSUNOBU REACTION; CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

CYCLIZATION; HISTAMINE AGONISTS; IMIDAZOLES; LIGANDS; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; RECEPTORS, HISTAMINE H3; STEREOISOMERISM;

EID: 0141940125     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.51.325     Document Type: Article

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