The histamine H4 receptor and potential therapeutic uses for H4 ligands

Mini-Reviews in Medicinal Chemistry

Volumn 4, Issue 9, 2004, Pages 993-1000

  Jablonowski, Jill A ^a   Carruthers, Nicholas I ^a   Thurmond, Robin L ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA METHYLHISTAMINE; ANTIHISTAMINIC AGENT; ASTEMIZOLE; BURIMAMIDE; CETIRIZINE; CHLORPHENIRAMINE; CIMETIDINE; CIPROXIFAN; CLOBENPROPIT; CLOZAPINE; CYPROHEPTADINE; DIMAPRIT; DIPHENHYDRAMINE; HISTAMINE DERIVATIVE; HISTAMINE H1 RECEPTOR ANTAGONIST; HISTAMINE H3 RECEPTOR; HISTAMINE H4 RECEPTOR; HYDROXYZINE; IMETIT; IMIDAZOLE DERIVATIVE; IMPROMIDINE; KETOTIFEN; LIGAND; LORATADINE; MEPYRAMINE; N METHYLHISTAMINE; RANITIDINE; THIOPERAMIDE; TRIPELENNAMINE; UNINDEXED DRUG; HISTAMINE RECEPTOR; PIPERAZINE; PIPERAZINE DERIVATIVE;

ALLERGIC RHINITIS; ANTIINFLAMMATORY ACTIVITY; ASTHMA; ATOPIC DERMATITIS; AUTOIMMUNE DISEASE; CHEMOTAXIS; COLITIS; DISEASE EXACERBATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; HISTAMINE RELEASE; HUMAN; INFLAMMATION; NEUROTRANSMITTER RELEASE; NONHUMAN; PAW EDEMA; RECEPTOR AFFINITY; SHORT SURVEY; STOMACH ACID SECRETION; STRUCTURE ACTIVITY RELATION; URTICARIA; ANIMAL; CHEMISTRY; METABOLISM; REVIEW;

ANIMALS; HISTAMINE ANTAGONISTS; HUMANS; LIGANDS; PIPERAZINES; RECEPTORS, HISTAMINE;

EID: 6444239061     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389557043403152     Document Type: Short Survey

References (58)

1. Ash, A. S. F; Schild, H. O. Br. J. Pharmacology, 1966, 27, 427-439.
2. Solt, A. H.; Walsh, J. H. Annu. Rev. Physiol., 1979 41, 35-53.
3. Arrang, J.M.; Garbarg, M.; Schwartz, J. C. Nature (London) 1983, 302, 832-837
4. Nguyen, T.; Shapiro, D. A.; George, S. R.; Setola, V.; Lee, D. K.; Cheng, R.; Rauser, L.; Lee, S. P.; Lynch, K. R.; Roth, B. L.; O'Dowd, B. F. Mol. Pharmacol., 2001, 59, 427-433.
5. Chen, J.; Liu, C.; Lovenberg, T. W. Eur. J. Pharmacol., 2003, 467, 57-65
6. Wiedemann, P.; Boenisch, H.; Oerters, F.; Bruess, M. J. Neural Transm., 2002, 109, 443-453.
7. Wellendorph, P.; Goodman, M. W.; Burstein, E. S.; Nash, N. R.; Brann, M. R.; Weiner, D. M. Neuropharmacology, 2002, 42, 929-940.
8. Coge, F.; Guenin, S.-P.; Audinot, V.; Renouard-Try, A.; Beauverger, P.; Macia, C.; Ouvry, C.; Nagel, N.; Rique, H.; Boutin, J. A.; Galizzi, J.-P. Biochem. J., 2001, 355, 279-288.
9. Tardivel-Lacombe, J.; Morisset, S.; Gbahou, F.; Schwartz, J.-C.; Arrang, J.-M. Neuroreport, 2001, 12, 321-324.
10. Drutel, G.; Peitsaro, N.; Karlstedt, K.; Wieland, K.; Smit, M. J.; Timmerman, H.; Panula, P.; Leurs, R. Mol. Pharmacol., 2001, 59, 1-8.
11. Liu, C.; Ma, X. J.; Lovenberg, T. W. Mol. Brain Res., 2000, 83, 145-150.
12. Liu, C.; Ma, X.-J.; Jiang, X.; Wilson, S. J.; Hofstra, C. L.; Blevitt, J.; Pyati, J.; Li, X.; Chai, W.; Carruthers, N.; Lovenberg, T. W. Mol. Pharmacol., 2001, 59, 420-426.
13. Zhu, Y.; Michalovich, D.; Wu, H.-L.; Tan, K. B.; Dytko, G. M.; Marman, I. J.; Boyce, R.; Alston, J.; Tierney, L. A.; Li, X.; Herrity, N. C.; Vawter, L.; Sarau, H. M.; Ames, R. S.; Davenport, C. M.; Hieble, J. P.; Wilson, S.; Bergsma, D. J.; Fitzgerald, L. R. Mol. Pharmacol., 2001, 59, 434-441.
14. Oda, T.; Morikawa, N.; Saito, Y.; Masuho, Y.; Matsumoto, S.-I. J. Biol. Chem., 2000, 275, 36781-36786.
15. Lovenberg, T. W.; Pyati, J.; Chang, H.; Wilson, S. J.; Erlander, M. G. J. Pharmacol. Exp. Ther., 2000, 293, 771-778.
16. Morse, K. L.; Behan, J.; Laz, T. M.; West, R. E., Jr.; Greenfeder, S. A.; Anthes, J. C.; Umland, S.; Wan, Y.; Hipkin, R. W.; Gonsiorek, W.; Shin, N.; Gustafson, E. L.; Qiao, X.; Wang, S.; Hedrick, J. A.; Greene, J.; Bayne, M.; Monsma, F. J., Jr. J. Pharmacol. Exp. Ther., 2001, 296, 1058-1066.
17. Hofstra, C. L.; Desai, P. J.; Thurmond, R. L.; Fung-Leung, W. P. J. Pharmacol. Exp. Ther., 2003, 305, 1212-1221.
18. Gantner, F.; Sakai, K.; Tusche, M. W.; Cruikshank, W. W.; Center, D. M.; Bacon, K. B. J. Pharmacol. Exper. Ther., 2002, 303, 300-307.
19. Coge, F.; Guenin, S.-P.; Rique, H.; Boutin, J. A.; Galizzi, J.-P. Biochem. Biophys. Res. Commun., 2001, 284, 301-309.
20. Liu, C.; Wilson, S. J.; Kuei, C.; Lovenberg, T. W. J. Pharmacol. Exp. Ther., 2001, 299, 121-130.
21. Oda, T.; Matsumoto, S.-i.; Masuho, Y.; Takasaki, J.; Matsumoto, M.; Kamohara, M.; Saito, T.; Ohishi, T.; Soga, T.; Hiyama, H.; Matsushime, H.; Furuichi, K. Biochimi. Biophys. Acta, 2002, 1575, 135-138.
22. Lovenberg, T. W.; Roland, B. L.; Wilson, S. J.; Jiang, X.; Pyati, J.; Huvar, A.; Jackson, M. R.; Erlander, M. G. Mol. Pharmacol. 1999, 55, 1101-1107.
23. O'Reilly, M.; Alpert, R.; Jenkinson, S.; Gladue, R. P.; Foo, S.; Trim, S.; Peter, B.; Trevethick, M.; Fidock, M. J.Recpt. Signal Transduct, 2002, 22, 431-448.
24. Hough, L. Mol. Pharmacol., 2001, 59, 415-419.
25. Lim, H. D., Bakker, R. A., Leurs, R. Abstracts European Histamine Research Society, XXXII Annual Meeting, 7-11 May 2003, Noordwijkerhout, The Netherlands, page 114.
26. Shah, C., McAtee, L., Breitenbucher, J. G., Rudolph, D., Li, X., Lovenberg, T. W., Mazur, C., Wilson, S. J., Carruthers, N. I. Bioorgan. Med. Chem. Lett., 2002, 12, 3309-3312.
27. Esbenshade, T. A., Krueger, K. M., Miller, T. R., Kang, C. H., Denny, L. I., Witte, D. G., Yao, B. B., Fox, G. B., Faghih, R., Bennani, Y. L., Williams, M., Hancock, A. A. J. Pharmacol. Exper. Ther., 2003, 305, 887-896.
28. Kathman, M.; Schlicker, E.; Gothert, M. Psychopharmacology 1994, 116,464.
29. Thurmond, R. Abstracts European Histamine Research Society, XXXII Annual Meeting, 7-11 May 2003, Noordwijkerhout, The Netherlands, page 153.
30. 4 ligands, Ortho-McNeil Pharmaceutical, Inc., USA. Carruthers, N. I.; Chai, W., Dvorak, C. A, Edwards, J. P., Grice, C. A., Jablonowski, J. A., Karlsson, L., Khatuya, H., Kreisberg, J. D., Kwok, A. K., Lovenberg, T. W., Ly, K. S., Pio, B., Shah, C. R., Sun, S., Thurmond, R. L., Wei, J., Xiao, W. PCT Int. Appl. (2002).
31. Jablonowski, J. A., Grice, C. A., Chai, W., Dvorak, C. A., Venable, J. D., Kwok, A. K., Ly, K. S., Wei, J., Baker, S. M., Desai, P. J., Jiang, W., Wilson, S. J., Thurmond, R. L., Karlsson, L., Edwards, J. P., Lovenberg T. W., Carruthers, N. I. J. Med. Chem., 2003, 46, 3162-3165.
32. Hashimoto, T., Harusawa, S., Araki, L., Zuiderveld, O. P., Smit, M. J., Imazu, T., Takashima, S., Yamamoto, Y., Sakamoto, Y., Kurihara, T., Leurs, R., Bakker, R. A., Yamatodani, A. J. Med. Chem. 2003, 46, 3957-3960.
33. Clark, R. A. F.; Gallin, J. I.; Kaplan, A. P. J. Exp. Med. 1975, 142, 1462-76.
34. Raible, D. G.; Lenahan, T.; Fayvilevich, Y.; Kosinski, R.; Schulman, E. S. Am. J. Resp. Crit. Care Med., 1994, 149 1506-11.
35. Kirby, J. G.; Hargreave, F. E.; Gleich, G. J.; O'Byrne, P. M. Am. Rev. Respir. Dis., 1987, 136, 379-83.
36. Crimi, E.; Chiaramondia, M.; Milanese, M.; Rossi, G. A.; Brusasco, V. Am. Rev. Respir. Dis., 1991, 144, 1282-6.
37. Amin, K.; Ludviksdottir, D.; Janson, C.; Nettelbladt, O.; Bjornsson, E.; Roomans, G. M.; Boman, G.; Seveus, L.; Venge, P. Am. J. Resp. Crit. Care Med., 2000, 162, 2295-301.
38. Gauvreau, G. M.; Lee, J. M.; Watson, R. M.; Irani, A. M.; Schwartz, L. B.; O'Byrne, P. M. Am. J. Resp. Crit. Care Med., 2000, 161, 1473-8.
39. Kassel, O.; De Blay, F.; Duvernelle, C.; Olgart, C.; Israel-Biet, D.; Krieger, P.; Moreau, L.; Muller, C.; Pauli, G.; Frossard, N. Clin. Exp. Allergy, 2001, 31, 1432-1440.
40. Fokkens, W. J.; Godthelp, T.; Holm, A. F.; Blom, H.; Mulder, P. G.; Vroom, T. M.; Rijntjes, E. Clin. Exp. Allergy, 1992, 22, 701-10.
41. Slater, A.; Smallman, L. A.; Drake-Lee, A. B. J. of Laryngol. Otol., 1996, 110, 929-33.
42. Krug, N.; Cruikshank, W. W.; Tschernig, T.; Erpenbeck, V. J.; Balke, K.; Hohlfeld, J. M.; Center, D. M.; Fabel, H. Am. J. Resp. Crit. Care Med., 2000, 162, 105-11.
43. Mashikian, V. M.; Tarpy, R. E.; Saukkonen, J. J.; Lim, K. G.; Fine, G. D.; Cruikshank, W. W.; Center, D. M. J. Allergy Clin. Immunol., 1998, 101, 786-792.
44. Nakamura, T.; Itadani, H.; Hidaka, Y.; Ohta, M.; Tanaka, K. Biochem. Biophys. Res. Commun., 2000, 279, 615-620.
45. Thurmond, R. L.; Desai, P. J.; Dunford, P. J.; Fung-Leung, W. -P.; Hofstra, C. L.; Jiang, W.; Nguyen, S.; Riley, J. P.; Sun, S.; Williams, K. N.; Edwards, J. P.; Karlsson, L. J. Pharmacol. Exper. Ther., 2004, 309, 404-413.
46. Rouleau, A.; Stark, H.; Schunack, W.; Schwartz, J.-C. J. Pharmacol. Exper. Ther., 2000, 295, 219-225.
47. Coruzzi, G.; Poli, E.; Pozzoli, C.; Nosalova, V.; Grandi, D.; Lazzaretti, M.; Schunack, W. Inflammation Research, 2002, 51, S31-S32.
48. Nosalova, V.; Cerna, S.; Schunack, W.; Grandi, D.; Coruzzi, G. Inflammation Research, 2001, 50, S108-S109.
49. Bertaccini, G.; Coruzzi, G.; Poli, E. Pharmacochemistry Library, 1998, 30, 59-111.
50. Howarth, P. H.; Salagean, M.; Dokic, D. Allergy, 2000, 55 Suppl. 64, 7-16.
51. Lordan, J. L.; Holgate, S. T. Clinical Allergy and Immunology, 2002, 17, 221-248.
52. Walsh, G. M. American Journal of Respiratory Medicine, 2002, 1, 27-34.
53. Larsen, J. S. Pharmacotherapy, 2001, 21, 28S-33S.
54. Hagermark, O. Skin Pharmacology, 1992, 5, 1-8.
55. Henz, B. M.; Metzenauer, P.; O'Keefe, E.; Zuberbier, T. Allergy (Copenhagen), 1998, 53, 180-183.
56. Krishnaswamy, G.; Kelley, J.; Johnson, D.; Youngberg, G.; Stone, W.; Huang, S. K.; Bieber, J.; Chi, D. S. Frontiers in Bioscience [online computer file ], 2001, 6, D1109-D1127.
57. Woolley, D. E. New. Eng. J. Med., 2003, 348 1709-1711.
58. Robbie-Ryan, M.; Brown, M. A. Curr. Opin. Immunol., 2002, 14, 728-733.