-
1
-
-
0028244816
-
Tumor necrosis factor: A pleiotropic cytokine and therapeutic target
-
Tracey, K. J. and Cerami, A. (1994) Tumor necrosis factor: a pleiotropic cytokine and therapeutic target. Annu. Rev. Med. 45, 491-503
-
(1994)
Annu. Rev. Med.
, vol.45
, pp. 491-503
-
-
Tracey, K.J.1
Cerami, A.2
-
2
-
-
0027333425
-
Tumor necrosis factor, other cytokines and disease
-
Tracey, K. J. and Cerami, A. (1993) Tumor necrosis factor, other cytokines and disease. Annu. Rev. Cell Biol. 9, 317-343
-
(1993)
Annu. Rev. Cell Biol.
, vol.9
, pp. 317-343
-
-
Tracey, K.J.1
Cerami, A.2
-
3
-
-
0035444539
-
Signal transduction by tumor necrosis factor and its relatives
-
DOI 10.1016/S0962-8924(01)02064-5, PII S0962892401020645
-
Baud, V. and Karin, M. (2001) Signal transduction by tumor necrosis factor and its relatives. Trends Cell Biol. 11, 372-377 (Pubitemid 32900529)
-
(2001)
Trends in Cell Biology
, vol.11
, Issue.9
, pp. 372-377
-
-
Baud, V.1
Karin, M.2
-
4
-
-
0037204948
-
TNF-R1 signaling: A beautiful pathway
-
Chen, G. and Goeddel, D. V. (2002) TNF-R1 signaling: a beautiful pathway. Science 296, 1634-1635
-
(2002)
Science
, vol.296
, pp. 1634-1635
-
-
Chen, G.1
Goeddel, D.V.2
-
5
-
-
0036184885
-
TNF ligands and receptors - A matter of life and death
-
MacEwan, D. J. (2002) TNF ligands and receptors - a matter of life and death. Br. J. Pharmacol. 135, 855-875
-
(2002)
Br. J. Pharmacol.
, vol.135
, pp. 855-875
-
-
MacEwan, D.J.1
-
6
-
-
0036806622
-
The TNF-TNF receptor system
-
Hehlgans, T. and Mannel, D. N. (2002) The TNF-TNF receptor system. Biol. Chem. 383, 1581-1585
-
(2002)
Biol. Chem.
, vol.383
, pp. 1581-1585
-
-
Hehlgans, T.1
Mannel, D.N.2
-
7
-
-
85047692516
-
Signalling pathways of the TNF superfamily: A double-edged sword
-
Aggarwal, B. B. (2003) Signalling pathways of the TNF superfamily: a double-edged sword. Nat. Rev. Immunol. 3, 745-756
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 745-756
-
-
Aggarwal, B.B.1
-
8
-
-
37249063841
-
TNFα blockade in human diseases: An overview of efficacy and safety
-
Lin, J., Ziring, D., Desai, S., Kim, S., Wong, M., Korin, Y., Braun, J., Reed, E., Gjertson, D. and Singh, R. R. (2008) TNFα blockade in human diseases: an overview of efficacy and safety. Clin. Immunol. 126, 13-30
-
(2008)
Clin. Immunol.
, vol.126
, pp. 13-30
-
-
Lin, J.1
Ziring, D.2
Desai, S.3
Kim, S.4
Wong, M.5
Korin, Y.6
Braun, J.7
Reed, E.8
Gjertson, D.9
Singh, R.R.10
-
9
-
-
37849052961
-
TNFα blockade in human diseases: Mechanisms and future directions
-
Wong, M., Ziring, D., Korin, Y., Desai, S., Kim, S., Lin, J., Gjertson, D., Braun, J., Reed, E. and Singh, R. R. (2008) TNFα blockade in human diseases: mechanisms and future directions. Clin. Immunol. 126, 121-136
-
(2008)
Clin. Immunol.
, vol.126
, pp. 121-136
-
-
Wong, M.1
Ziring, D.2
Korin, Y.3
Desai, S.4
Kim, S.5
Lin, J.6
Gjertson, D.7
Braun, J.8
Reed, E.9
Singh, R.R.10
-
10
-
-
0003180184
-
Die Heilwirkung des Erysipels auf Geschwulste
-
Bruns, P. (1868) Die Heilwirkung des Erysipels auf Geschwulste Beitr. Klin. Chir. 3, 443-446
-
(1868)
Beitr. Klin. Chir.
, vol.3
, pp. 443-446
-
-
Bruns, P.1
-
11
-
-
0000937789
-
Contribution to the knowledge of Sarcoma
-
Coley, W. B. (1891) Contribution to the knowledge of Sarcoma. Ann. Surg. 14, 199-220
-
(1891)
Ann. Surg.
, vol.14
, pp. 199-220
-
-
Coley, W.B.1
-
12
-
-
0016723594
-
An endotoxin-induced serum factor that causes necrosis of tumors
-
Carswell, E. A., Old, L. J., Kassel, R. L., Green, S., Fiore, N. and Williamson, B. (1975) An endotoxin-induced serum factor that causes necrosis of tumors. Proc. Natl. Acad. Sci. U. S. A. 72, 3666-3670
-
(1975)
Proc. Natl. Acad. Sci. U. S. A.
, vol.72
, pp. 3666-3670
-
-
Carswell, E.A.1
Old, L.J.2
Kassel, R.L.3
Green, S.4
Fiore, N.5
Williamson, B.6
-
13
-
-
0022369998
-
Tumor necrosis factor (TNF)
-
Old, L. J. (1985) Tumor necrosis factor (TNF). Science 230, 630-632
-
(1985)
Science
, vol.230
, pp. 630-632
-
-
Old, L.J.1
-
14
-
-
0021923645
-
Human tumor necrosis factor. Production, purification, and characterization
-
Aggarwal, B. B., Kohr, W. J., Hass, P. E., Moffat, B., Spencer, S. A., Henzel, W. J., Bringman, T. S., Nedwin, G. E., Goeddel, D. V. and Harkins, R. N. (1985) Human tumor necrosis factor. Production, purification, and characterization. J. Biol. Chem. 260, 2345-2354
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 2345-2354
-
-
Aggarwal, B.B.1
Kohr, W.J.2
Hass, P.E.3
Moffat, B.4
Spencer, S.A.5
Henzel, W.J.6
Bringman, T.S.7
Nedwin, G.E.8
Goeddel, D.V.9
Harkins, R.N.10
-
15
-
-
0021344360
-
Human lymphotoxin production by a lymphoblastoid cell line, purification, and initial characterization
-
Aggarwal, B. B., Moffat, B. and Harkins, R. N. (1984) Human lymphotoxin production by a lymphoblastoid cell line, purification, and initial characterization. J. Biol. Chem. 259, 686-691
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 686-691
-
-
Aggarwal, B.B.1
Moffat, B.2
Harkins, R.N.3
-
16
-
-
34250014777
-
How TNF was recognized as a key mechanism of disease
-
Clark, I. A. (2007) How TNF was recognized as a key mechanism of disease. Cytokine Growth Factor Rev. 18, 335-343
-
(2007)
Cytokine Growth Factor Rev.
, vol.18
, pp. 335-343
-
-
Clark, I.A.1
-
17
-
-
0028485654
-
Processing of tumour necrosis factor-α precursor by metalloproteinases
-
DOI 10.1038/370555a0
-
Gearing, A. J., Beckett, P., Christodoulou, M., Churchill, M., Clements, J., Davidson, A. H., Drummond, A. H., Galloway, W. A., Gilbert, R., Gordon, J. L. et al. (1994) Processing of tumour necrosis factor-α precursor by metalloproteinases. Nature 370, 555-557 (Pubitemid 24264920)
-
(1994)
Nature
, vol.370
, Issue.6490
, pp. 555-557
-
-
Gearing, A.J.H.1
Beckett, P.2
Christodoulou, M.3
Churchill, M.4
Clements, J.5
Davidson, A.H.6
Drummond, A.H.7
Galloway, W.A.8
Gilbert, R.9
Gordon, J.L.10
Leber, T.M.11
Mangan, M.12
Miller, K.13
Nayee, P.14
Owen, K.15
Patel, S.16
Thomas, W.17
Wells, G.18
Wood, L.M.19
Wooley, K.20
more..
-
18
-
-
0036133646
-
Tumor necrosis factor-α converting enzyme
-
Black, R. A. (2002) Tumor necrosis factor-α converting enzyme. Int. J. Biochem. Cell Biol. 34, 1-5
-
(2002)
Int. J. Biochem. Cell Biol.
, vol.34
, pp. 1-5
-
-
Black, R.A.1
-
19
-
-
0034254453
-
TNF α and the TNF receptor superfamily: Structure-function relationship(s)
-
Idriss, H. T. and Naismith, J. H. (2000) TNF α and the TNF receptor superfamily: structure-function relationship(s). Microsc. Res. Tech. 50, 184-195
-
(2000)
Microsc. Res. Tech.
, vol.50
, pp. 184-195
-
-
Idriss, H.T.1
Naismith, J.H.2
-
20
-
-
8044257704
-
A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
-
DOI 10.1038/385729a0
-
Black, R. A., Rauch, C. T., Kozlosky, C. J., Peschon, J. J., Slack, J. L., Wolfson, M. F., Castner, B. J., Stocking, K. L., Reddy, P., Srinivasan, S. et al. (1997) A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells. Nature 385, 729-733 (Pubitemid 27098094)
-
(1997)
Nature
, vol.385
, Issue.6618
, pp. 729-733
-
-
Black, R.A.1
Rauch, C.T.2
Kozlosky, C.J.3
Peschon, J.J.4
Slack, J.L.5
Wolfson, M.F.6
Castner, B.J.7
Stocking, K.L.8
Reddy, P.9
Srinivasan, S.10
Nelson, N.11
Boiani, N.12
Schooley, K.A.13
Gerhart, M.14
Davis, R.15
Fitzner, J.N.16
Johnson, R.S.17
Paxton, R.J.18
March, C.J.19
Cerretti, D.P.20
more..
-
21
-
-
8044250278
-
Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α
-
DOI 10.1038/385733a0
-
Moss, M. L., Jin, S. L., Milla, M. E., Bickett, D. M., Burkhart, W., Carter, H. L., Chen, W. J., Clay, W. C., Didsbury, J. R., Hassler, D. et al. (1997) Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α. Nature 385, 733-736 (Pubitemid 27098095)
-
(1997)
Nature
, vol.385
, Issue.6618
, pp. 733-736
-
-
Moss, M.L.1
Jin, S.-L.C.2
Milla, M.E.3
Burkhart, W.4
Carter, H.L.5
Chen, W.-J.6
Clay, W.C.7
Didsbury, J.R.8
Hassler, D.9
Hoffman, C.R.10
Kost, T.A.11
Lambert, M.H.12
Leesnitzer, M.A.13
McCauley, P.14
McGeehan, G.15
Mitchell, J.16
Moyer, M.17
Pahel, G.18
Rocque, W.19
Overton, L.K.20
Schoenen, F.21
Seaton, T.22
Su, J.-L.23
Warner, J.24
Willard, D.25
Becherer, J.D.26
more..
-
22
-
-
0002469445
-
The 3-D structure of TNF
-
Beutler, B, ed., Raven Press, New York, USA
-
Sprang, S. R. and Eck, M. J. (1992) The 3-D structure of TNF. In Tumor Necrosis Factors: the Molecules and Their Emerging Role in Medicine (Beutler, B, ed.), pp. 11-32, Raven Press, New York, USA
-
(1992)
Tumor Necrosis Factors: The Molecules and Their Emerging Role in Medicine
, pp. 11-32
-
-
Sprang, S.R.1
Eck, M.J.2
-
23
-
-
0032746314
-
Signal transduction by tumour necrosis factor and tumour necrosis factor related ligands and their receptors
-
Darnay, B. G. and Aggarwal, B. B. (1999) Signal transduction by tumour necrosis factor and tumour necrosis factor related ligands and their receptors. Ann. Rheum. Dis. 58 (Suppl. 1), 12-113
-
(1999)
Ann. Rheum. Dis.
, vol.58
, Issue.SUPPL. 1
, pp. 12-113
-
-
Darnay, B.G.1
Aggarwal, B.B.2
-
24
-
-
44849097798
-
The TNF Superfamily-2008
-
Ware, C. F. (2008) The TNF Superfamily-2008. Cytokine Growth Factor Rev. 19, 183-186
-
(2008)
Cytokine Growth Factor Rev.
, vol.19
, pp. 183-186
-
-
Ware, C.F.1
-
25
-
-
0036121098
-
TNF receptor subtype signalling: Differences and cellular consequences
-
MacEwan, D. J. (2002) TNF receptor subtype signalling: differences and cellular consequences. Cell. Signalling 14, 477-492
-
(2002)
Cell. Signalling
, vol.14
, pp. 477-492
-
-
MacEwan, D.J.1
-
26
-
-
0025313006
-
A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins
-
Smith, C. A., Davis, T., Anderson, D., Solam, L., Beckmann, M. P., Jerzy, R., Dower, S. K., Cosman, D. and Goodwin, R. G. (1990) A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins. Science 248, 1019-1023
-
(1990)
Science
, vol.248
, pp. 1019-1023
-
-
Smith, C.A.1
Davis, T.2
Anderson, D.3
Solam, L.4
Beckmann, M.P.5
Jerzy, R.6
Dower, S.K.7
Cosman, D.8
Goodwin, R.G.9
-
27
-
-
0029114596
-
Two tumour necrosis factor receptors: Structure and function
-
Vandenabeele, P., Declercq, W., Beyaert, R. and Fiers, W. (1995) Two tumour necrosis factor receptors: structure and function. Trends Cell Biol. 5, 392-399
-
(1995)
Trends Cell Biol.
, vol.5
, pp. 392-399
-
-
Vandenabeele, P.1
Declercq, W.2
Beyaert, R.3
Fiers, W.4
-
28
-
-
0034733682
-
A domain in TNF receptors that mediates ligand-independent receptor assembty and signaling
-
DOI 10.1126/science.288.5475.2351
-
Chan, F. K., Chun, H. J., Zheng, L., Siegel, R. M., Bui, K. L. and Lenardo, M. J. (2000) A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling. Science 288, 2351-2354 (Pubitemid 30448156)
-
(2000)
Science
, vol.288
, Issue.5475
, pp. 2351-2354
-
-
Chan, F.K.-M.1
Chun, H.J.2
Zheng, L.3
Siegel, R.M.4
Bui, K.L.5
Lenardo, M.J.6
-
29
-
-
0029551303
-
Tumor necrosis factor (TNF) receptors in cellular signaling of soluble and membrane-expressed TNF
-
Grell, M. (1995) Tumor necrosis factor (TNF) receptors in cellular signaling of soluble and membrane-expressed TNF. J. Inflamm. 47, 8-17
-
(1995)
J. Inflamm.
, vol.47
, pp. 8-17
-
-
Grell, M.1
-
30
-
-
0028866022
-
The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80kDa tumor necrosis factor receptor
-
Grell, M., Douni, E., Wajant, H., Lohden, M., Clauss, M., Maxeiner, B., Georgopoulos, S., Lesslauer, W., Kollias, G., Pfizenmaier, K. and Scheurich, P. (1995) The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80kDa tumor necrosis factor receptor. Cell 83, 793-802
-
(1995)
Cell
, vol.83
, pp. 793-802
-
-
Grell, M.1
Douni, E.2
Wajant, H.3
Lohden, M.4
Clauss, M.5
Maxeiner, B.6
Georgopoulos, S.7
Lesslauer, W.8
Kollias, G.9
Pfizenmaier, K.10
Scheurich, P.11
-
31
-
-
0031882913
-
The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor
-
Grell, M., Wajant, H., Zimmermann, G. and Scheurich, P. (1998) The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor. Proc. Natl. Acad. Sci. U. S. A. 95, 570-575
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 570-575
-
-
Grell, M.1
Wajant, H.2
Zimmermann, G.3
Scheurich, P.4
-
32
-
-
0037276438
-
Tumor necrosis factor signaling
-
Wajant, H., Pfizenmaier, K. and Scheurich, P. (2003) Tumor necrosis factor signaling. Cell Death Differ. 10, 45-65
-
(2003)
Cell Death Differ.
, vol.10
, pp. 45-65
-
-
Wajant, H.1
Pfizenmaier, K.2
Scheurich, P.3
-
33
-
-
0035380712
-
A novel p75TNF receptor isoform mediating NF-κ-B activation
-
Seitz, C., Muller, P., Krieg, R. C., Mannel, D. N. and Hehlgans, T. (2001) A novel p75TNF receptor isoform mediating NF-κ-B activation. J. Biol. Chem. 276, 19390-19395
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19390-19395
-
-
Seitz, C.1
Muller, P.2
Krieg, R.C.3
Mannel, D.N.4
Hehlgans, T.5
-
34
-
-
0032969285
-
Tumor necrosis factor receptor and Fas signaling mechanisms
-
Wallach, D., Varfolomeev, E. E., Malinin, N. L., Goltsev, Y. V., Kovalenko, A. V. and Boldin, M. P. (1999) Tumor necrosis factor receptor and Fas signaling mechanisms. Annu. Rev. Immunol. 17, 331-367
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 331-367
-
-
Wallach, D.1
Varfolomeev, E.E.2
Malinin, N.L.3
Goltsev, Y.V.4
Kovalenko, A.V.5
Boldin, M.P.6
-
35
-
-
0027275490
-
A novel domain within the 55 kd TNF receptor signals cell death
-
Tartaglia, L. A., Ayres, T. M., Wong, G. H. and Goeddel, D. V. (1993) A novel domain within the 55 kd TNF receptor signals cell death. Cell 74, 845-853
-
(1993)
Cell
, vol.74
, pp. 845-853
-
-
Tartaglia, L.A.1
Ayres, T.M.2
Wong, G.H.3
Goeddel, D.V.4
-
36
-
-
0033593655
-
Prevention of constitutive TNF receptor 1signaling by silencer of death domains
-
Jiang, Y., Woronicz, J. D., Liu, W. and Goeddel, D. V. (1999) Prevention of constitutive TNF receptor 1signaling by silencer of death domains. Science 283, 543-546
-
(1999)
Science
, vol.283
, pp. 543-546
-
-
Jiang, Y.1
Woronicz, J.D.2
Liu, W.3
Goeddel, D.V.4
-
37
-
-
0028295054
-
Differential roles of two types of the TNF receptor in TNF-induced cytotoxicity, DNA fragmentation, and differentiation
-
Higuchi, M. and Aggarwal, B. B. (1994) Differential roles of two types of the TNF receptor in TNF-induced cytotoxicity, DNA fragmentation, and differentiation. J. Immunol. 152, 4017-4025 (Pubitemid 24111073)
-
(1994)
Journal of Immunology
, vol.152
, Issue.8
, pp. 4017-4025
-
-
Higuchi, M.1
Aggarwal, B.B.2
-
38
-
-
0033538073
-
Inhibition of receptor internalization by monodansylcadaverine selectively blocks p55 tumor necrosis factor receptor death domain signaling
-
Schutze, S., Machleidt, T., Adam, D., Schwandner, R., Wiegmann, K., Kruse, M. L., Heinrich, M., Wickel, M. and Kranke, M. (1999) Inhibition of receptor internalization by monodansylcadaverine selectively blocks p55 tumor necrosis factor receptor death domain signaling. J. Biol. Chem. 274, 10203-10212
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10203-10212
-
-
Schutze, S.1
Machleidt, T.2
Adam, D.3
Schwandner, R.4
Wiegmann, K.5
Kruse, M.L.6
Heinrich, M.7
Wickel, M.8
Kranke, M.9
-
39
-
-
0030032106
-
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
-
Hsu, H., Shu, H. B., Pan, M. G. and Goeddel, D. V. (1996) TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 84, 299-308
-
(1996)
Cell
, vol.84
, pp. 299-308
-
-
Hsu, H.1
Shu, H.B.2
Pan, M.G.3
Goeddel, D.V.4
-
40
-
-
0030298294
-
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
-
DOI 10.1016/S0092-8674(00)81375-6
-
Liu, Z. G., Hsu, H., Goeddel, D. V. and Karin, M. (1996) Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell 87, 565-576 (Pubitemid 26374329)
-
(1996)
Cell
, vol.87
, Issue.3
, pp. 565-576
-
-
Liu, Z.G.1
Hsu, H.2
Goeddel, D.V.3
Karin, M.4
-
41
-
-
0030746401
-
Apoptosis and carcinogenesis
-
Wyllie, A. H. (1997) Apoptosis and carcinogenesis. Eur. J. Cell Biol. 73, 189-197
-
(1997)
Eur. J. Cell Biol.
, vol.73
, pp. 189-197
-
-
Wyllie, A.H.1
-
42
-
-
0035085627
-
Apoptotic and necrotic cell death induced by death domain receptors
-
Denecker, G., Vercammen, D., Declercq, W. and Vandenabeele, P. (2001) Apoptotic and necrotic cell death induced by death domain receptors. Cell. Mol. Life Sci. 58, 356-370
-
(2001)
Cell. Mol. Life Sci.
, vol.58
, pp. 356-370
-
-
Denecker, G.1
Vercammen, D.2
Declercq, W.3
Vandenabeele, P.4
-
43
-
-
0034910509
-
Death receptor-induced apoptotic and necrotic cell death: Differential role of caspases and mitochondria
-
DOI 10.1038/sj.cdd.4400883
-
Denecker, G., Vercammen, D., Steemans, M., Vanden Berghe, T., Brouckaert, G., Van Loo, G., Zhivotovsky, B., Fiers, W., Grooten, J., Declercq, W. and Vandenabeele, P. (2001) Death receptor- induced apoptotic and necrotic cell death: differential role of caspases and mitochondria. Cell Death Differ. 8, 829-840 (Pubitemid 32725534)
-
(2001)
Cell Death and Differentiation
, vol.8
, Issue.8
, pp. 829-840
-
-
Denecker, G.1
Vercammen, D.2
Steemans, M.3
Vanden, B.T.4
Brouckaert, G.5
Van, L.G.6
Zhivotovsky, B.7
Fiers, W.8
Grooten, J.9
Declercq, W.10
Vandenabeele, P.11
-
44
-
-
34247641557
-
Signaling for survival and apoptosis in the immune system
-
Mak, T. W. and Yeh, W. C. (2002) Signaling for survival and apoptosis in the immune system. Arthritis Res. 4 (Suppl. 3), S243-S252
-
(2002)
Arthritis Res.
, vol.4
, Issue.SUPPL. 3
-
-
Mak, T.W.1
Yeh, W.C.2
-
45
-
-
0029007855
-
The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation
-
Hsu, H., Xiong, J. and Goeddel, D. V. (1995) The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation. Cell 81, 495-504
-
(1995)
Cell
, vol.81
, pp. 495-504
-
-
Hsu, H.1
Xiong, J.2
Goeddel, D.V.3
-
46
-
-
0032575714
-
Death receptors: Signaling and modulation
-
Ashkenazi, A. and Dixit, V. M. (1998) Death receptors: signaling and modulation. Science 281, 1305-1308
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
47
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo, X., Budihardjo, I., Zou, H., Slaughter, C. and Wang, X. (1998) Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94, 481-490 (Pubitemid 28391864)
-
(1998)
Cell
, vol.94
, Issue.4
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
48
-
-
0035890085
-
The expanding role of mitochondria in apoptosis
-
Wang, X. (2001) The expanding role of mitochondria in apoptosis. Genes Dev. 15, 2922-2933
-
(2001)
Genes Dev.
, vol.15
, pp. 2922-2933
-
-
Wang, X.1
-
49
-
-
0035283079
-
Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3
-
Wieder, T., Essmann, F., Prokop, A., Schmelz, K., Schulze-Osthoff, K., Beyaert, R., Dorken, B. and Daniel, P. T. (2001) Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3. Blood 97, 1378-1387
-
(2001)
Blood
, vol.97
, pp. 1378-1387
-
-
Wieder, T.1
Essmann, F.2
Prokop, A.3
Schmelz, K.4
Schulze-Osthoff, K.5
Beyaert, R.6
Dorken, B.7
Daniel, P.T.8
-
50
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis, R. J. (2000) Signal transduction by the JNK group of MAP kinases. Cell 103, 239-252
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
51
-
-
0035504199
-
Type II tumour necrosis factor-α receptor (TNFR2) activates c-Jun N-terminal kinase (JNK) but not mitogen-activated protein kinase (MAPK) or p38 MAPK pathways
-
DOI 10.1042/0264-6021:3590525
-
Jupp, O. J., McFarlane, S. M., Anderson, H. M., Littlejohn, A. F., Mohamed, A. A., MacKay, R. H., Vandenabeele, P. and MacEwan, D. J. (2001) Type II tumour necrosis factor-α receptor (TNFR2) activates c-Jun N-terminal kinase (JNK) but not mitogen-activated protein kinase (MAPK) or p38 MAPK pathways. Biochem. J. 359, 525-535 (Pubitemid 33063376)
-
(2001)
Biochemical Journal
, vol.359
, Issue.3
, pp. 525-535
-
-
Jupp, O.J.1
McFarlane, S.M.2
Anderson, H.M.3
Littlejohn, A.F.4
Mohamed, A.A.A.5
MacKay, R.H.6
Vandenabeele, P.7
MacEwan, D.J.8
-
52
-
-
0033563101
-
Signaling by proinflammatory cytokines: Oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain
-
Baud, V., Liu, Z. G., Bennett, B., Suzuki, N., Xia, Y. and Karin, M. (1999) Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain. Genes Dev. 13, 1297-1308 (Pubitemid 29250197)
-
(1999)
Genes and Development
, vol.13
, Issue.10
, pp. 1297-1308
-
-
Baud, V.1
Liu, Z.-G.2
Bennett, B.3
Suzuki, N.4
Xia, Y.5
Karin, M.6
-
53
-
-
0031013545
-
Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway
-
Natoli, G., Costanzo, A., Ianni, A., Templeton, D. J., Woodgett, J. R., Balsano, C. and Levrero, M. (1997) Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway. Science 275, 200-203
-
(1997)
Science
, vol.275
, pp. 200-203
-
-
Natoli, G.1
Costanzo, A.2
Ianni, A.3
Templeton, D.J.4
Woodgett, J.R.5
Balsano, C.6
Levrero, M.7
-
54
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
-
Ichijo, H., Nishida, E., Irie, K., ten Dijke, P., Saitoh, M., Moriguchi, T., Takagi, M., Matsumoto, K., Miyazono, K. and Gotoh, Y. (1997) Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275, 90-94
-
(1997)
Science
, vol.275
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
Ten Dijke, P.4
Saitoh, M.5
Moriguchi, T.6
Takagi, M.7
Matsumoto, K.8
Miyazono, K.9
Gotoh, Y.10
-
55
-
-
0032158987
-
ASK1 is essential for JNK/SAPK activation by TRAF2
-
Nishitoh, H., Saitoh, M., Mochida, Y., Takeda, K., Nakano, H., Rothe, M., Miyazono, K. and Ichijo, H. (1998) ASK1 is essential for JNK/SAPK activation by TRAF2. Mol. Cell 2, 389-395 (Pubitemid 128379279)
-
(1998)
Molecular Cell
, vol.2
, Issue.3
, pp. 389-395
-
-
Nishitoh, H.1
Saitoh, M.2
Mochida, Y.3
Takeda, K.4
Nakano, H.5
Rothe, M.6
Miyazono, K.7
Ichijo, H.8
-
56
-
-
0032575591
-
Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting protein associates with a mitogen-activated protein kinase kinase kinase upstream of MKK6 and p38
-
Yuasa, T., Ohno, S., Kehrl, J. H. and Kyriakis, J. M. (1998) Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting protein associates with a mitogen-activated protein kinase kinase kinase upstream of MKK6 and p38. J. Biol. Chem. 273, 22681-22692
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 22681-22692
-
-
Yuasa, T.1
Ohno, S.2
Kehrl, J.H.3
Kyriakis, J.M.4
-
58
-
-
0038433303
-
JunD mediates survival signaling by the JNK signal transduction pathway
-
DOI 10.1016/S1097-2765(03)00203-X
-
Lamb, J. A., Ventura, J. J., Hess, P., Flavell, R. A. and Davis, R. J. (2003) JunD mediates survival signaling by the JNK signal transduction pathway. Mol. Cell 11, 1479-1489 (Pubitemid 36776535)
-
(2003)
Molecular Cell
, vol.11
, Issue.6
, pp. 1479-1489
-
-
Lamb, J.A.1
Ventura, J.-J.2
Hess, P.3
Flavell, R.A.4
Davis, R.J.5
-
59
-
-
10044265209
-
JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species
-
DOI 10.1101/gad.1223004
-
Ventura, J. J., Cogswell, P., Flavell, R. A., Baldwin, Jr, A. S. and Davis, R. J. (2004) JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species. Genes Dev. 18, 2905-2915 (Pubitemid 39602309)
-
(2004)
Genes and Development
, vol.18
, Issue.23
, pp. 2905-2915
-
-
Ventura, J.-J.1
Cogswell, P.2
Flavell, R.A.3
Baldwin Jr., A.S.4
Davis, R.J.5
-
60
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
-
Saitoh, M., Nishitoh, H., Fujii, M., Takeda, K., Tobiume, K., Sawada, Y., Kawabata, M., Miyazono, K. and Ichijo, H. (1998) Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J. 17, 2596-2606
-
(1998)
EMBO J.
, vol.17
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
Takeda, K.4
Tobiume, K.5
Sawada, Y.6
Kawabata, M.7
Miyazono, K.8
Ichijo, H.9
-
61
-
-
0032504189
-
Reactive oxygen species-and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-α signal transduction
-
Gotoh, Y. and Cooper, J. A. (1998) Reactive oxygen species-and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-α signal transduction. J. Biol. Chem. 273, 17477-17482
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17477-17482
-
-
Gotoh, Y.1
Cooper, J.A.2
-
62
-
-
14844327760
-
Reactive oxygen species promote TNFα-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
-
DOI 10.1016/j.cell.2004.12.041
-
Kamata, H., Honda, S., Maeda, S., Chang, L., Hirata, H. and Karin, M. (2005) Reactive oxygen species promote TNFα-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 120, 649-661 (Pubitemid 40343077)
-
(2005)
Cell
, vol.120
, Issue.5
, pp. 649-661
-
-
Kamata, H.1
Honda, S.-I.2
Maeda, S.3
Chang, L.4
Hirata, H.5
Karin, M.6
-
63
-
-
33749341552
-
TNF receptor superfamily-induced cell death: Redox-dependent execution
-
Shen, H. M. and Pervaiz, S. (2006) TNF receptor superfamily-induced cell death: redox-dependent execution. FASEB J. 20, 1589-1598
-
(2006)
FASEB J.
, vol.20
, pp. 1589-1598
-
-
Shen, H.M.1
Pervaiz, S.2
-
64
-
-
0030906497
-
AP-1 function and regulation
-
Karin, M., Liu, Z. and Zandi, E. (1997) AP-1 function and regulation. Curr. Opin. Cell Biol. 9, 240-246
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 240-246
-
-
Karin, M.1
Liu, Z.2
Zandi, E.3
-
65
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis, J. M. and Avruch, J. (2001) Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev. 81, 807-869
-
(2001)
Physiol. Rev.
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
66
-
-
0033214236
-
Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
-
Lin, Y., Devin, A., Rodriguez, Y. and Liu, Z. G. (1999) Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev. 13, 2514-2526
-
(1999)
Genes Dev.
, vol.13
, pp. 2514-2526
-
-
Lin, Y.1
Devin, A.2
Rodriguez, Y.3
Liu, Z.G.4
-
67
-
-
0036205260
-
Arachidonic acid release by CPLA2 may be causally related to NO-induced apoptosis in vascular smooth muscle cells
-
Pilane, C. M. and LaBelle, E. F. (2002) Arachidonic acid release by CPLA2 may be causally related to NO-induced apoptosis in vascular smooth muscle cells. J. Cell. Physiol. 191, 191-197
-
(2002)
J. Cell. Physiol.
, vol.191
, pp. 191-197
-
-
Pilane, C.M.1
LaBelle, E.F.2
-
68
-
-
0032619056
-
Characterization of arachidonic acid-induced apoptosis
-
Wolf, L. A. and Laster, S. M. (1999) Characterization of arachidonic acid-induced apoptosis. Cell Biochem. Biophys. 30, 353-368
-
(1999)
Cell Biochem. Biophys.
, vol.30
, pp. 353-368
-
-
Wolf, L.A.1
Laster, S.M.2
-
69
-
-
0032827976
-
Potentiation by vitamin D analogs of TNFα and ceramide-induced apoptosis in MCF-7 cells is associated with activation of cytosolic phospholipase A2
-
Pirianov, G., Danielsson, C., Carlberg, C., James, S. Y. and Colston, K. W. (1999) Potentiation by vitamin D analogs of TNFα and ceramide-induced apoptosis in MCF-7 cells is associated with activation of cytosolic phospholipase A2. Cell Death Differ. 6, 890-901
-
(1999)
Cell Death Differ.
, vol.6
, pp. 890-901
-
-
Pirianov, G.1
Danielsson, C.2
Carlberg, C.3
James, S.Y.4
Colston, K.W.5
-
70
-
-
33645804600
-
Secretory phospholipase A2 induces apoptosis through TNF-α and cytochrome c-mediated caspase cascade in murine macrophage RAW 264.7 cells
-
Lee, C., Park, D. W., Lee, J., Lee, T. I., Kim, Y J., Lee, Y. S. and Baek, S. H. (2006) Secretory phospholipase A2 induces apoptosis through TNF-α and cytochrome c-mediated caspase cascade in murine macrophage RAW 264.7 cells. Eur. J. Pharmacol. 536, 47-53
-
(2006)
Eur. J. Pharmacol.
, vol.536
, pp. 47-53
-
-
Lee, C.1
Park, D.W.2
Lee, J.3
Lee, T.I.4
Kim, Y.J.5
Lee, Y.S.6
Baek, S.H.7
-
71
-
-
0032193215
-
Selective inhibitors of cytosolic or secretory phospholipase A2 block TNF-induced activation of transcription factor nuclear factor-κB and expression of ICAM-1
-
Thommesen, L., Sjursen, W., Gasvik, K., Hanssen, W., Brekke, O. L., Skattebol, L., Holmeide, A. K., Espevik, T., Johansen, B. and Laegreid, A. (1998) Selective inhibitors of cytosolic or secretory phospholipase A2 block TNF-induced activation of transcription factor nuclear factor-κB and expression of ICAM-1. J. Immunol. 161, 3421-3430
-
(1998)
J. Immunol.
, vol.161
, pp. 3421-3430
-
-
Thommesen, L.1
Sjursen, W.2
Gasvik, K.3
Hanssen, W.4
Brekke, O.L.5
Skattebol, L.6
Holmeide, A.K.7
Espevik, T.8
Johansen, B.9
Laegreid, A.10
-
72
-
-
0035839557
-
Functional coupling between secretory and cytosolic phospholipase A2 modulates tumor necrosis factor-α- and interleukin-1β-induced NF-κB activation
-
Anthonsen, M. W., Solhaug, A. and Johansen, B. (2001) Functional coupling between secretory and cytosolic phospholipase A2 modulates tumor necrosis factor-α- and interleukin-1β-induced NF-κB activation. J. Biol. Chem. 276, 30527-30536
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30527-30536
-
-
Anthonsen, M.W.1
Solhaug, A.2
Johansen, B.3
-
73
-
-
0032402976
-
Differential activation of phospholipases during necrosis or apoptosis: A comparative study using tumor necrosis factor and anti-Fas antibodies
-
De Valck, D., Vercammen, D., Fiers, W. and Beyaert, R. (1998) Differential activation of phospholipases during necrosis or apoptosis: a comparative study using tumor necrosis factor and anti-Fas antibodies. J. Cell. Biochem. 71, 392-399
-
(1998)
J. Cell. Biochem.
, vol.71
, pp. 392-399
-
-
De Valck, D.1
Vercammen, D.2
Fiers, W.3
Beyaert, R.4
-
74
-
-
0032526890
-
Failure to activate cytosolic phospholipase A2 causes TNF resistance in human leukemic cells
-
Wu, Y. L., Jiang, X. R., Newland, A. C. and Kelsey, S. M. (1998) Failure to activate cytosolic phospholipase A2 causes TNF resistance in human leukemic cells. J. Immunol. 160, 5929-5935
-
(1998)
J. Immunol.
, vol.160
, pp. 5929-5935
-
-
Wu, Y.L.1
Jiang, X.R.2
Newland, A.C.3
Kelsey, S.M.4
-
75
-
-
0032520043
-
1,25-Dihydroxyvitamin D3 protects human leukemic cells from tumor necrosis factor-induced apoptosis via inactivation of cytosolic phospholipase A2
-
Wu, Y. L., Jiang, X. R., Lillington, D. M., Allen, P. D., Newland, A. C. and Kelsey, S. M. (1998) 1,25-Dihydroxyvitamin D3 protects human leukemic cells from tumor necrosis factor-induced apoptosis via inactivation of cytosolic phospholipase A2. Cancer Res. 58, 633-640
-
(1998)
Cancer Res.
, vol.58
, pp. 633-640
-
-
Wu, Y.L.1
Jiang, X.R.2
Lillington, D.M.3
Allen, P.D.4
Newland, A.C.5
Kelsey, S.M.6
-
76
-
-
0030611270
-
Phospholipase A2 is necessary for tumor necrosis factor α-induced ceramide generation in L929 cells
-
Jayadev, S., Hayter, H. L., Andrieu, N., Gamard, C. J., Liu, B., Balu, R., Hayakawa, M., Ito, F. and Hannun, Y. A. (1997) Phospholipase A2 is necessary for tumor necrosis factor α-induced ceramide generation in L929 cells. J. Biol. Chem. 272, 17196-17203
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17196-17203
-
-
Jayadev, S.1
Hayter, H.L.2
Andrieu, N.3
Gamard, C.J.4
Liu, B.5
Balu, R.6
Hayakawa, M.7
Ito, F.8
Hannun, Y.A.9
-
77
-
-
0025810578
-
A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP
-
Clark, J. D., Lin, L. L., Kriz, R. W., Ramesha, C. S., Sultzman, L. A., Lin, A. Y., Milona, N. and Knopf, J. L. (1991) A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP. Cell 65, 1043-1051
-
(1991)
Cell
, vol.65
, pp. 1043-1051
-
-
Clark, J.D.1
Lin, L.L.2
Kriz, R.W.3
Ramesha, C.S.4
Sultzman, L.A.5
Lin, A.Y.6
Milona, N.7
Knopf, J.L.8
-
78
-
-
0029671282
-
Elevated cPLA2 levels as a mechanism by which the p70 TNF and p75 NGF receptors enhance apoptosis
-
MacEwan, D. J. (1996) Elevated cPLA2 levels as a mechanism by which the p70 TNF and p75 NGF receptors enhance apoptosis. FEBS Lett. 379, 77-81
-
(1996)
FEBS Lett.
, vol.379
, pp. 77-81
-
-
MacEwan, D.J.1
-
79
-
-
0027336294
-
Cytoplasmic phospholipase A2 activity and gene expression are stimulated by tumor necrosis factor: Dexamethasone blocks the induced synthesis
-
Hoeck, W. G., Ramesha, C. S., Chang, D. J., Fan, N. and Heller, R. A. (1993) Cytoplasmic phospholipase A2 activity and gene expression are stimulated by tumor necrosis factor: dexamethasone blocks the induced synthesis. Proc. Natl. Acad. Sci. U. S. A. 90, 4475-4479
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 4475-4479
-
-
Hoeck, W.G.1
Ramesha, C.S.2
Chang, D.J.3
Fan, N.4
Heller, R.A.5
-
80
-
-
0026471205
-
Cell killing and induction of manganous superoxide dismutase by tumor necrosis factor-α is mediated by lipoxygenase metabolites of arachidonic acid
-
Chang, D. J., Ringold, G. M. and Heller, R. A. (1992) Cell killing and induction of manganous superoxide dismutase by tumor necrosis factor-α is mediated by lipoxygenase metabolites of arachidonic acid. Biochem. Biophys. Res. Commun. 188, 538-546
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.188
, pp. 538-546
-
-
Chang, D.J.1
Ringold, G.M.2
Heller, R.A.3
-
81
-
-
0037084504
-
All TRAFs are not created equal: Common and distinct molecular mechanisms of TRAF-mediated signal transduction
-
Chung, J. Y., Park, Y. C., Ye, H. and Wu, H. (2002) All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction. J. Cell Sci. 115, 679-688
-
(2002)
J. Cell Sci.
, vol.115
, pp. 679-688
-
-
Chung, J.Y.1
Park, Y.C.2
Ye, H.3
Wu, H.4
-
83
-
-
0034705271
-
A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction
-
Park, Y. C., Ye, H., Hsia, C., Segal, D., Rich, R. L., Liou, H. C., Myszka, D. G. and Wu, H. (2000) A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction. Cell 101, 777-787
-
(2000)
Cell
, vol.101
, pp. 777-787
-
-
Park, Y.C.1
Ye, H.2
Hsia, C.3
Segal, D.4
Rich, R.L.5
Liou, H.C.6
Myszka, D.G.7
Wu, H.8
-
84
-
-
0033725155
-
The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation
-
Devin, A., Cook, A., Lin, Y., Rodriguez, Y., Kelliher, M. and Liu, Z. (2000) The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation. Immunity 12, 419-429
-
(2000)
Immunity
, vol.12
, pp. 419-429
-
-
Devin, A.1
Cook, A.2
Lin, Y.3
Rodriguez, Y.4
Kelliher, M.5
Liu, Z.6
-
85
-
-
0032033132
-
The death domain kinase RIP mediates the TNF-induced NF-κB signal
-
Kelliher, M. A., Grimm, S., Ishida, Y., Kuo, F., Stanger, B. Z. and Leder, P. (1998) The death domain kinase RIP mediates the TNF-induced NF-κB signal. Immunity 8, 297-303
-
(1998)
Immunity
, vol.8
, pp. 297-303
-
-
Kelliher, M.A.1
Grimm, S.2
Ishida, Y.3
Kuo, F.4
Stanger, B.Z.5
Leder, P.6
-
86
-
-
0035965232
-
Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-κB activation and protection from cell death
-
Tada, K., Okazaki, T., Sakon, S., Kobarai, T., Kurosawa, K., Yamaoka, S., Hashimoto, H., Mak, T. W., Yagita, H., Okumura, K. et al. (2001) Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-κB activation and protection from cell death. J. Biol. Chem. 276, 36530-36534
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 36530-36534
-
-
Tada, K.1
Okazaki, T.2
Sakon, S.3
Kobarai, T.4
Kurosawa, K.5
Yamaoka, S.6
Hashimoto, H.7
Mak, T.W.8
Yagita, H.9
Okumura, K.10
-
87
-
-
0031897632
-
NF-κB and Rel proteins: Evolutionarily conserved mediators of immune responses
-
Ghosh, S., May, M. J. and Kopp, E. B. (1998) NF-κB and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16, 225-260
-
(1998)
Annu. Rev. Immunol.
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
May, M.J.2
Kopp, E.B.3
-
88
-
-
0028174061
-
Function and activation of NF-κB in the immune system
-
Baeuerle, P. A. and Henkel, T. (1994) Function and activation of NF-κB in the immune system. Annu. Rev. Immunol. 12, 141-179
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 141-179
-
-
Baeuerle, P.A.1
Henkel, T.2
-
89
-
-
34147099560
-
TNFR1-induced NF-κB, but not ERK, p38MAPK or JNK activation, mediates TNF-induced ICAM-1 and VCAM-1 expression on endothelial cells
-
Zhou, Z., Connell, M. C. and MacEwan, D. J. (2007) TNFR1-induced NF-κB, but not ERK, p38MAPK or JNK activation, mediates TNF-induced ICAM-1 and VCAM-1 expression on endothelial cells. Cell. Signalling 19, 1238-1248
-
(2007)
Cell. Signalling
, vol.19
, pp. 1238-1248
-
-
Zhou, Z.1
Connell, M.C.2
MacEwan, D.J.3
-
90
-
-
4444376712
-
Signaling to NF-κB
-
Hayden, M. S. and Ghosh, S. (2004) Signaling to NF-κB. Genes Dev. 18, 2195-2224
-
(2004)
Genes Dev.
, vol.18
, pp. 2195-2224
-
-
Hayden, M.S.1
Ghosh, S.2
-
92
-
-
33645312379
-
Circuitry of nuclear factor κB signaling
-
Hoffmann, A. and Baltimore, D. (2006) Circuitry of nuclear factor κB signaling. Immunol. Rev. 210, 171-186
-
(2006)
Immunol. Rev.
, vol.210
, pp. 171-186
-
-
Hoffmann, A.1
Baltimore, D.2
-
93
-
-
0036234459
-
Missing pieces in the NF-κB puzzle
-
Ghosh, S. and Karin, M. (2002) Missing pieces in the NF-κB puzzle. Cell (Suppl.) 109, S81-S96
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
Ghosh, S.1
Karin, M.2
-
94
-
-
0035021123
-
The α and κ subunits of IκB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF
-
Devin, A., Lin, Y., Yamaoka, S., Li, Z., Karin, M. and Liu, Z. (2001) The α and κ subunits of IκB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF. Mol. Cell. Biol. 21, 3986-3994
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3986-3994
-
-
Devin, A.1
Lin, Y.2
Yamaoka, S.3
Li, Z.4
Karin, M.5
Liu, Z.6
-
95
-
-
0033712615
-
Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation
-
Zhang, S. Q., Kovalenko, A., Cantarella, G. and Wallach, D. (2000) Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation. Immunity 12, 301-311
-
(2000)
Immunity
, vol.12
, pp. 301-311
-
-
Zhang, S.Q.1
Kovalenko, A.2
Cantarella, G.3
Wallach, D.4
-
96
-
-
0031017618
-
MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1
-
Malinin, N. L., Boldin, M. P., Kovalenko, A. V. and Wallach, D. (1997) MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1. Nature 385, 540-544
-
(1997)
Nature
, vol.385
, pp. 540-544
-
-
Malinin, N.L.1
Boldin, M.P.2
Kovalenko, A.V.3
Wallach, D.4
-
97
-
-
0032583947
-
NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176
-
Ling, L., Cao, Z. and Goeddel, D. V. (1998) NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176. Proc. Natl. Acad. Sci. U. S. A. 95, 3792-3797
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 3792-3797
-
-
Ling, L.1
Cao, Z.2
Goeddel, D.V.3
-
98
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-κB activity
-
Karin, M. and Ben-Neriah, Y (2000) Phosphorylation meets ubiquitination: the control of NF-κB activity. Annu. Rev. Immunol. 18, 621-663
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
99
-
-
0035891320
-
Inhibition of JNK activation through NF-κB target genes
-
Tang, G., Minemoto, Y., Dibling, B., Purcell, N. H., Li, Z., Karin, M. and Lin, A. (2001) Inhibition of JNK activation through NF-κB target genes. Nature 414, 313-317
-
(2001)
Nature
, vol.414
, pp. 313-317
-
-
Tang, G.1
Minemoto, Y.2
Dibling, B.3
Purcell, N.H.4
Li, Z.5
Karin, M.6
Lin, A.7
-
100
-
-
0035889252
-
Induction of gadd45β by NF-κB downregulates pro-apoptotic JNK signalling
-
De Smaele, E., Zazzeroni, F., Papa, S., Nguyen, D. U., Jin, R., Jones, J., Cong, R. and Franzoso, G. (2001) Induction of gadd45β by NF-κB downregulates pro-apoptotic JNK signalling. Nature 414, 308-313
-
(2001)
Nature
, vol.414
, pp. 308-313
-
-
De Smaele, E.1
Zazzeroni, F.2
Papa, S.3
Nguyen, D.U.4
Jin, R.5
Jones, J.6
Cong, R.7
Franzoso, G.8
-
101
-
-
0030746740
-
Casper is a FADD- and caspase-related inducer of apoptosis
-
Shu, H. B., Halpin, D. R. and Goeddel, D. V. (1997) Casper is a FADD- and caspase-related inducer of apoptosis. Immunity 6, 751-763
-
(1997)
Immunity
, vol.6
, pp. 751-763
-
-
Shu, H.B.1
Halpin, D.R.2
Goeddel, D.V.3
-
102
-
-
0042467735
-
Cell signalling: Cell survival and a Gadd45-factor deficiency
-
Amanullah, A., Azam, N., Balliet, A., Hollander, C., Hoffman, B., Fornace, A. and Liebermann, D. (2003) Cell signalling: cell survival and a Gadd45-factor deficiency. Nature 424, 741
-
(2003)
Nature
, vol.424
, pp. 741
-
-
Amanullah, A.1
Azam, N.2
Balliet, A.3
Hollander, C.4
Hoffman, B.5
Fornace, A.6
Liebermann, D.7
-
103
-
-
0035037802
-
Characterization of XIAP-deficient mice
-
Harlin, H., Reffey, S. B., Duckett, C. S., Lindsten, T. and Thompson, C. B. (2001) Characterization of XIAP-deficient mice. Mol. Cell. Biol. 21, 3604-3608
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3604-3608
-
-
Harlin, H.1
Reffey, S.B.2
Duckett, C.S.3
Lindsten, T.4
Thompson, C.B.5
-
104
-
-
27144526668
-
NF-κB meets ROS: An 'iron-ic' encounter
-
Papa, S., Bubici, C., Pham, C. G., Zazzeroni, F. and Franzoso, G. (2005) NF-κB meets ROS: an 'iron-ic' encounter. Cell Death Differ. 12, 1259-1262
-
(2005)
Cell Death Differ.
, vol.12
, pp. 1259-1262
-
-
Papa, S.1
Bubici, C.2
Pham, C.G.3
Zazzeroni, F.4
Franzoso, G.5
-
105
-
-
1542405935
-
Reactive oxygen species (ROS), troublemakers between nuclear factor-κB (NF-κB) and c-Jun NH(2)-terminal kinase (JNK)
-
Zhang, Y. and Chen, F. (2004) Reactive oxygen species (ROS), troublemakers between nuclear factor-κB (NF-κB) and c-Jun NH(2)-terminal kinase (JNK). Cancer Res. 64, 1902-1905
-
(2004)
Cancer Res.
, vol.64
, pp. 1902-1905
-
-
Zhang, Y.1
Chen, F.2
-
106
-
-
85047685805
-
NF-κB-dependent MnSOD expression protects adenocarcinoma cells from TNF-α-induced apoptosis
-
Delhalle, S., Deregowski, V., Benoit, V., Merville, M. P. and Bours, V. (2002) NF-κB-dependent MnSOD expression protects adenocarcinoma cells from TNF-α-induced apoptosis. Oncogene 21, 3917-3924
-
(2002)
Oncogene
, vol.21
, pp. 3917-3924
-
-
Delhalle, S.1
Deregowski, V.2
Benoit, V.3
Merville, M.P.4
Bours, V.5
-
107
-
-
8344260568
-
Ferritin heavy chain upregulation by NF-κB inhibits TNFα-induced apoptosis by suppressing reactive oxygen species
-
Pham, C. G., Bubici, C., Zazzeroni, F., Papa, S., Jones, J., Alvarez, K., Jayawardena, S., De Smaele, E., Cong, R., Beaumont, C., Torti, F. M., Torti, S. V. and Franzoso, G. (2004) Ferritin heavy chain upregulation by NF-κB inhibits TNFα-induced apoptosis by suppressing reactive oxygen species. Cell 119, 529-542
-
(2004)
Cell
, vol.119
, pp. 529-542
-
-
Pham, C.G.1
Bubici, C.2
Zazzeroni, F.3
Papa, S.4
Jones, J.5
Alvarez, K.6
Jayawardena, S.7
De Smaele, E.8
Cong, R.9
Beaumont, C.10
Torti, F.M.11
Torti, S.V.12
Franzoso, G.13
-
108
-
-
0030854676
-
How does superoxide dismutase protect against tumor necrosis factor: A hypothesis informed by effect of superoxide on 'free' iron
-
Liochev, S. I. and Fridovich, I. (1997) How does superoxide dismutase protect against tumor necrosis factor: a hypothesis informed by effect of superoxide on 'free' iron. Free Radical Biol. Med. 23, 668-671
-
(1997)
Free Radical Biol. Med.
, vol.23
, pp. 668-671
-
-
Liochev, S.I.1
Fridovich, I.2
-
109
-
-
0035379555
-
Akt stimulates the transactivation potential of the RelA/P65 Subunit of NF-κB through utilization of the IκB kinase and activation of the mitogen-activated protein kinase p38
-
Madrid, L. V., Mayo, M. W., Reuther, J. Y. and Baldwin, Jr, A. S. (2001) Akt stimulates the transactivation potential of the RelA/P65 Subunit of NF-κB through utilization of the IκB kinase and activation of the mitogen-activated protein kinase p38. J. Biol. Chem. 276, 18934-18940
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18934-18940
-
-
Madrid, L.V.1
Mayo, M.W.2
Reuther, J.Y.3
Baldwin Jr., A.S.4
-
110
-
-
0034720896
-
Kinase regulation in inflammatory response
-
Delhase, M., Li, N. and Karin, M. (2000) Kinase regulation in inflammatory response. Nature 406, 367-368
-
(2000)
Nature
, vol.406
, pp. 367-368
-
-
Delhase, M.1
Li, N.2
Karin, M.3
-
111
-
-
0034612636
-
Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation
-
Hoeflich, K. P., Luo, J., Rubie, E. A., Tsao, M. S., Jin, O. and Woodgett, J. R. (2000) Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation. Nature 406, 86-90
-
(2000)
Nature
, vol.406
, pp. 86-90
-
-
Hoeflich, K.P.1
Luo, J.2
Rubie, E.A.3
Tsao, M.S.4
Jin, O.5
Woodgett, J.R.6
-
112
-
-
0030447483
-
The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor lsignaling complex
-
Shu, H. B., Takeuchi, M. and Goeddel, D. V. (1996) The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor lsignaling complex. Proc. Natl. Acad. Sci. U. S. A. 93, 13973-13978
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 13973-13978
-
-
Shu, H.B.1
Takeuchi, M.2
Goeddel, D.V.3
-
113
-
-
0029595282
-
The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins
-
Rothe, M., Pan, M. G., Henzel, W. J., Ayres, T. M. and Goeddel, D. V. (1995) The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. Cell 83, 1243-1252
-
(1995)
Cell
, vol.83
, pp. 1243-1252
-
-
Rothe, M.1
Pan, M.G.2
Henzel, W.J.3
Ayres, T.M.4
Goeddel, D.V.5
-
114
-
-
0030698127
-
The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
-
Roy, N., Deveraux, Q. L., Takahashi, R., Salvesen, G. S. and Reed, J. C. (1997) The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J. 16, 6914-6925
-
(1997)
EMBO J.
, vol.16
, pp. 6914-6925
-
-
Roy, N.1
Deveraux, Q.L.2
Takahashi, R.3
Salvesen, G.S.4
Reed, J.C.5
-
115
-
-
0034282432
-
The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7
-
Huang, H., Joazeiro, C. A., Bonfoco, E., Kamada, S., Leverson, J. D. and Hunter, T. (2000) The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7. J. Biol. Chem. 275, 26661-26664
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26661-26664
-
-
Huang, H.1
Joazeiro, C.A.2
Bonfoco, E.3
Kamada, S.4
Leverson, J.D.5
Hunter, T.6
-
116
-
-
0026094301
-
Tumor necrosis factor induces rapid production of 1′2′ diacylglycerol by a phosphatidylcholine-specific phospholipase C
-
Schutze, S., Berkovic, D., Tomsing, O., Unger, C. and Kronke, M. (1991) Tumor necrosis factor induces rapid production of 1′2′diacylglycerol by a phosphatidylcholine-specific phospholipase C. J. Exp. Med. 174, 975-988
-
(1991)
J. Exp. Med.
, vol.174
, pp. 975-988
-
-
Schutze, S.1
Berkovic, D.2
Tomsing, O.3
Unger, C.4
Kronke, M.5
-
117
-
-
0026778831
-
Human 55-kDa receptor for tumor necrosis factor coupled to signal transduction cascades
-
Wiegmann, K., Schutze, S., Kampen, E., Himmler, A., Machleidt, T. and Kronke, M. (1992) Human 55-kDa receptor for tumor necrosis factor coupled to signal transduction cascades. J. Biol. Chem. 267, 17997-18001
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 17997-18001
-
-
Wiegmann, K.1
Schutze, S.2
Kampen, E.3
Himmler, A.4
Machleidt, T.5
Kronke, M.6
-
118
-
-
0034667519
-
Phosphatidylcholine-specific phospholipase C and phospholipase D are respectively implicated in mitogen-activated protein kinase and nuclear factor κB activation in tumour-necrosis-factor-α-treated immature acute-myeloid-leukaemla cells
-
Pio, I., Lautier, D., Levade, T., Sekouri, H., Jaffrezou, J. P., Laurent, G. and Bettaieb, A. (2000) Phosphatidylcholine-specific phospholipase C and phospholipase D are respectively implicated in mitogen-activated protein kinase and nuclear factor κB activation in tumour-necrosis-factor-α-treated immature acute-myeloid-leukaemla cells. Biochem. J. 351, 459-467
-
(2000)
Biochem. J.
, vol.351
, pp. 459-467
-
-
Pio, I.1
Lautier, D.2
Levade, T.3
Sekouri, H.4
Jaffrezou, J.P.5
Laurent, G.6
Bettaieb, A.7
-
119
-
-
0026451081
-
Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
-
Nishizuka, Y. (1992) Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C Science 258, 607-614
-
(1992)
Science
, vol.258
, pp. 607-614
-
-
Nishizuka, Y.1
-
120
-
-
0027398962
-
Tumor necrosis factor cytotoxicity is associated with phospholipase D activation
-
De Valck, D., Beyaert, R., Van Roy, F. and Fiers, W. (1993) Tumor necrosis factor cytotoxicity is associated with phospholipase D activation. Eur. J. Biochem. 212, 491-497
-
(1993)
Eur. J. Biochem.
, vol.212
, pp. 491-497
-
-
De Valck, D.1
Beyaert, R.2
Van Roy, F.3
Fiers, W.4
-
121
-
-
0032584077
-
Changes of phospholipase D activity in TNF-α and anti-Fas/Apo1 monoclonal antibody induced apoptosis in HL-60 and A20 cells
-
Kang, J. H., Shin, I. and Han, J. S. (1998) Changes of phospholipase D activity in TNF-α and anti-Fas/Apo1 monoclonal antibody induced apoptosis in HL-60 and A20 cells. Exp. Mol. Med. 30, 21-27
-
(1998)
Exp. Mol. Med.
, vol.30
, pp. 21-27
-
-
Kang, J.H.1
Shin, I.2
Han, J.S.3
-
122
-
-
0035019077
-
PLD pathway involved in carbachol-induced CI- secretion: Possible role of TNF-α
-
Oprins, J. C., van der Burg, C., Meijer, H. P., Munnik, T. and Groot, J. A. (2001) PLD pathway involved in carbachol-induced CI- secretion: possible role of TNF-α. Am. J. Physiol. Cell Physiol. 280, C789-C795
-
(2001)
Am. J. Physiol. Cell Physiol.
, vol.280
-
-
Oprins, J.C.1
Van Der Burg, C.2
Meijer, H.P.3
Munnik, T.4
Groot, J.A.5
-
123
-
-
0035943693
-
Phospholipase D is required in the signaling pathway leading to p38 MAPK activation in neutrophil-like HL-60 cells, stimulated by N-formyl-methionyl- leucyl-phenylalanine
-
Bechoua, S. and Daniel, L. W. (2001) Phospholipase D is required in the signaling pathway leading to p38 MAPK activation in neutrophil-like HL-60 cells, stimulated by N-formyl-methionyl-leucyl-phenylalanine. J. Biol. Chem. 276, 31752-31759
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 31752-31759
-
-
Bechoua, S.1
Daniel, L.W.2
-
124
-
-
0036177948
-
Tumour necrosis factor α potentiates ion secretion induced by histamine in a human intestinal epithelial cell line and in mouse colon: Involvement of the phospholipase D pathway
-
Oprins, J. C., van der Burg, C., Meijer, H. P., Munnik, T. and Groot, J. A. (2002) Tumour necrosis factor α potentiates ion secretion induced by histamine in a human intestinal epithelial cell line and in mouse colon: involvement of the phospholipase D pathway. Gut 50, 314-321
-
(2002)
Gut
, vol.50
, pp. 314-321
-
-
Oprins, J.C.1
Van Der Burg, C.2
Meijer, H.P.3
Munnik, T.4
Groot, J.A.5
-
125
-
-
0031843535
-
Phospholipase D: A novel major player in signal transduction
-
Gomez-Cambronero, J. and Keire, P. (1998) Phospholipase D: a novel major player in signal transduction. Cell Signalling 10, 387-397
-
(1998)
Cell Signalling
, vol.10
, pp. 387-397
-
-
Gomez-Cambronero, J.1
Keire, P.2
-
126
-
-
23644455714
-
Phospholipase D: A lipid centric review
-
Jenkins, G. M. and Frohman, M. A. (2005) Phospholipase D: a lipid centric review. Cell. Mol. Life Sci. 62, 2305-2316
-
(2005)
Cell. Mol. Life Sci.
, vol.62
, pp. 2305-2316
-
-
Jenkins, G.M.1
Frohman, M.A.2
-
127
-
-
34248373648
-
The potential for phospholipase D as a new therapeutic target
-
Huang, P. and Frohman, M. A. (2007) The potential for phospholipase D as a new therapeutic target. Expert Opin. Ther. Targets 11, 707-716
-
(2007)
Expert Opin. Ther. Targets
, vol.11
, pp. 707-716
-
-
Huang, P.1
Frohman, M.A.2
-
128
-
-
2342639554
-
Phospholipase D
-
McDermott, M., Wakelam, M. J. and Morris, A. J. (2004) Phospholipase D. Biochem. Cell Biol. 82, 225-253
-
(2004)
Biochem. Cell Biol.
, vol.82
, pp. 225-253
-
-
McDermott, M.1
Wakelam, M.J.2
Morris, A.J.3
-
129
-
-
0036196957
-
Phospholipase D and immune receptor signalling
-
Melendez, A. J. and Allen, J. M. (2002) Phospholipase D and immune receptor signalling. Semin. Immunol. 14, 49-55
-
(2002)
Semin. Immunol.
, vol.14
, pp. 49-55
-
-
Melendez, A.J.1
Allen, J.M.2
-
130
-
-
44449140589
-
Phospholipase D1 plays a key role in TNF-α signaling
-
Sethu, S., Mendez-Corao, G. and Melendez, A. J. (2008) Phospholipase D1 plays a key role in TNF-α signaling. J. Immunol. 180, 6027-6034
-
(2008)
J. Immunol.
, vol.180
, pp. 6027-6034
-
-
Sethu, S.1
Mendez-Corao, G.2
Melendez, A.J.3
-
132
-
-
0037201947
-
The role of phosphatidic acid in the regulation of the Ras/MEK/Erk signaling cascade
-
Andresen, B. T., Rizzo, M. A., Shome, K. and Romero, G. (2002) The role of phosphatidic acid in the regulation of the Ras/MEK/Erk signaling cascade. FEBS Lett. 531, 65-68
-
(2002)
FEBS Lett.
, vol.531
, pp. 65-68
-
-
Andresen, B.T.1
Rizzo, M.A.2
Shome, K.3
Romero, G.4
-
133
-
-
0037203353
-
Roles of phospholipase D in apoptosis and pro-survival
-
Nozawa, Y. (2002) Roles of phospholipase D in apoptosis and pro-survival. Biochim. Biophys. Acta 1585, 77-86
-
(2002)
Biochim. Biophys. Acta
, vol.1585
, pp. 77-86
-
-
Nozawa, Y.1
-
134
-
-
33750577641
-
Phospholipase D protects ECV304 cells against TNFα-induced apoptosis
-
Birbes, H., Zeiller, C., Komati, H., Nemoz, G., Lagarde, M. and Prigent, A. F. (2006) Phospholipase D protects ECV304 cells against TNFα-induced apoptosis. FEBS Lett. 580, 6224-6232
-
(2006)
FEBS Lett.
, vol.580
, pp. 6224-6232
-
-
Birbes, H.1
Zeiller, C.2
Komati, H.3
Nemoz, G.4
Lagarde, M.5
Prigent, A.F.6
-
135
-
-
0033140462
-
Phospholipase D activation in endothelial cells is redox sensitive
-
Parinandi, N. L., Scribner, W. M., Vepa, S., Shi, S. and Natarajan, V. (1999) Phospholipase D activation in endothelial cells is redox sensitive. Antioxid. Redox Signalling 1, 193-210
-
(1999)
Antioxid. Redox Signalling
, vol.1
, pp. 193-210
-
-
Parinandi, N.L.1
Scribner, W.M.2
Vepa, S.3
Shi, S.4
Natarajan, V.5
-
136
-
-
0028076002
-
The role of diacylglycerol and ceramide in tumor necrosis factor and interleukin-1 signal transduction
-
Schutze, S., Machleidt, T. and Kranke, M. (1994) The role of diacylglycerol and ceramide in tumor necrosis factor and interleukin-1 signal transduction. J. Leukocyte Biol. 56, 533-541
-
(1994)
J. Leukocyte Biol.
, vol.56
, pp. 533-541
-
-
Schutze, S.1
Machleidt, T.2
Kranke, M.3
-
137
-
-
0034703090
-
Functional dichotomy of protein kinase C (PKC) in tumor necrosis factor-α (TNF-α) signal transduction in L929 cells. Translocation and inactivation of PKC by TNF-α
-
Lee, J. Y., Hannun, Y. A. and Obeid, L. M. (2000) Functional dichotomy of protein kinase C (PKC) in tumor necrosis factor-α (TNF-α) signal transduction in L929 cells. Translocation and inactivation of PKC by TNF-α. J. Biol. Chem. 275, 29290-29298
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 29290-29298
-
-
Lee, J.Y.1
Hannun, Y.A.2
Obeid, L.M.3
-
138
-
-
0033551661
-
Involvement of protein kinase C-β and ceramide in tumor necrosis factor-α-induced but not Fas-induced apoptosis of human myeloid leukemia cells
-
Laouar, A., Glesne, D. and Huberman, E. (1999) Involvement of protein kinase C-β and ceramide in tumor necrosis factor-α-induced but not Fas-induced apoptosis of human myeloid leukemia cells. J. Biol. Chem. 274, 23526-23534
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 23526-23534
-
-
Laouar, A.1
Glesne, D.2
Huberman, E.3
-
139
-
-
0030931876
-
Caspases: The executioners of apoptosis
-
Cohen, G. M. (1997) Caspases: the executioners of apoptosis. Biochem. J. 326, 1-16
-
(1997)
Biochem. J.
, vol.326
, pp. 1-16
-
-
Cohen, G.M.1
-
140
-
-
0029003788
-
PKC zeta is a molecular switch in signal transduction of TNF-α, bifunctionally regulated by ceramide and arachidonic acid
-
Muller, G., Ayoub, M., Storz, P., Rennecke, J., Fabbro, D. and Pfizenmaier, K. (1995) PKC zeta is a molecular switch in signal transduction of TNF-α, bifunctionally regulated by ceramide and arachidonic acid. EMBO J. 14, 1961-1969
-
(1995)
EMBO J.
, vol.14
, pp. 1961-1969
-
-
Muller, G.1
Ayoub, M.2
Storz, P.3
Rennecke, J.4
Fabbro, D.5
Pfizenmaier, K.6
-
141
-
-
0033153320
-
The interaction of p62 with RIP links the atypical PKCs to NF-κB activation
-
Sanz, L., Sanchez, P., Lallena, M. J., Diaz-Meco, M. T. and Moscat, J. (1999) The interaction of p62 with RIP links the atypical PKCs to NF-κB activation. EMBO J. 18, 3044-3053
-
(1999)
EMBO J.
, vol.18
, pp. 3044-3053
-
-
Sanz, L.1
Sanchez, P.2
Lallena, M.J.3
Diaz-Meco, M.T.4
Moscat, J.5
-
142
-
-
0033559395
-
Role of the protein kinase C lambda/iota isoform in nuclear factor-κB activation by interleukin-1β or tumor necrosis factor-α: Cell type specificities
-
Bonizzi, G., Piette, J., Schoonbroodt, S., Merville, M. P. and Bours, V. (1999) Role of the protein kinase C lambda/iota isoform in nuclear factor-κB activation by interleukin-1β or tumor necrosis factor-α: cell type specificities. Biochem. Pharmacol. 57, 713-720
-
(1999)
Biochem. Pharmacol.
, vol.57
, pp. 713-720
-
-
Bonizzi, G.1
Piette, J.2
Schoonbroodt, S.3
Merville, M.P.4
Bours, V.5
-
143
-
-
0026560014
-
Tumor necrosis factor-α activates the sphingomyelin signal transduction pathway in a cell-free system
-
Dressler, K. A., Mathias, S. and Kolesnick, R. N. (1992) Tumor necrosis factor-α activates the sphingomyelin signal transduction pathway in a cell-free system. Science 255, 1715-1718
-
(1992)
Science
, vol.255
, pp. 1715-1718
-
-
Dressler, K.A.1
Mathias, S.2
Kolesnick, R.N.3
-
144
-
-
0028031699
-
Neutral sphingomyelinase action stimulates signal transduction of tumor necrosis factor-α in the synthesis of cholesteryl esters in human fibroblasts
-
Chatterjee, S. (1994) Neutral sphingomyelinase action stimulates signal transduction of tumor necrosis factor-α in the synthesis of cholesteryl esters in human fibroblasts. J. Biol. Chem. 269, 879-882
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 879-882
-
-
Chatterjee, S.1
-
145
-
-
0026458406
-
TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced 'acidic' sphingomyelin breakdown
-
Schutze, S., Potthoff, K., Machleidt, T., Berkovic, D., Wiegmann, K. and Kranke, M. (1992) TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced 'acidic' sphingomyelin breakdown. Cell 71, 765-776
-
(1992)
Cell
, vol.71
, pp. 765-776
-
-
Schutze, S.1
Potthoff, K.2
Machleidt, T.3
Berkovic, D.4
Wiegmann, K.5
Kranke, M.6
-
146
-
-
0028108015
-
Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling
-
Wiegmann, K., Schutze, S., Machleidt, T., Witte, D. and Kranke, M. (1994) Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling. Cell 78, 1005-1015
-
(1994)
Cell
, vol.78
, pp. 1005-1015
-
-
Wiegmann, K.1
Schutze, S.2
Machleidt, T.3
Witte, D.4
Kranke, M.5
-
147
-
-
0023574186
-
Acid sphingomyelinase from human urine: Purification and characterization
-
Quintern, L. E., Weitz, G., Nehrkorn, H., Tager, J. M., Schram, A. W. and Sandhoff, K. (1987) Acid sphingomyelinase from human urine: purification and characterization. Biochim. Biophys. Acta 922, 323-336
-
(1987)
Biochim. Biophys. Acta
, vol.922
, pp. 323-336
-
-
Quintern, L.E.1
Weitz, G.2
Nehrkorn, H.3
Tager, J.M.4
Schram, A.W.5
Sandhoff, K.6
-
148
-
-
0023555012
-
1,2-Diacylglycerols but not phorbol esters stimulate sphingomyelin hydrolysis in GH3 pituitary cells
-
Kolesnick, R. N. (1987) 1,2-Diacylglycerols but not phorbol esters stimulate sphingomyelin hydrolysis in GH3 pituitary cells. J. Biol. Chem. 262, 16759-16762
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 16759-16762
-
-
Kolesnick, R.N.1
-
149
-
-
0027183695
-
Tumor necrosis factor activation of the sphingomyelin pathway signals nuclear factor κB translocation in intact HL-60 cells
-
Yang, Z., Costanzo, M., Golde, D. W. and Kolesnick, R. N. (1993) Tumor necrosis factor activation of the sphingomyelin pathway signals nuclear factor κB translocation in intact HL-60 cells. J. Biol. Chem. 268, 20520-20523
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 20520-20523
-
-
Yang, Z.1
Costanzo, M.2
Golde, D.W.3
Kolesnick, R.N.4
-
150
-
-
0032958623
-
TNF-α increases ceramide without inducing apoptosis in alveolar type II epithelial cells
-
Mallampalli, R. K., Peterson, E. J., Carter, A. B., Salome, R. G., Mathur, S. N. and Koretzky, G. A. (1999) TNF-α increases ceramide without inducing apoptosis in alveolar type II epithelial cells. Am. J. Physiol. 276, L481-L490
-
(1999)
Am. J. Physiol.
, vol.276
-
-
Mallampalli, R.K.1
Peterson, E.J.2
Carter, A.B.3
Salome, R.G.4
Mathur, S.N.5
Koretzky, G.A.6
-
151
-
-
0027327212
-
Tumor necrosis factor-α (TNF-α) signal transduction through ceramide. Dissociation of growth inhibitory effects of TNF-α from activation of nuclear factor-κB
-
Dbaibo, G. S., Obeid, L. M. and Hannun, Y. A. (1993) Tumor necrosis factor-α (TNF-α) signal transduction through ceramide. Dissociation of growth inhibitory effects of TNF-α from activation of nuclear factor-κB. J. Biol. Chem. 268, 17762-17766
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 17762-17766
-
-
Dbaibo, G.S.1
Obeid, L.M.2
Hannun, Y.A.3
-
152
-
-
0034661482
-
Sphingosine 1-phosphate signalling in mammalian cells
-
Pyne, S. and Pyne, N. J. (2000) Sphingosine 1-phosphate signalling in mammalian cells. Biochem. J. 349, 385-402
-
(2000)
Biochem. J.
, vol.349
, pp. 385-402
-
-
Pyne, S.1
Pyne, N.J.2
-
153
-
-
15244341285
-
Sphingosine kinase signalling in immune cells
-
Kee, T. H., Vit, P. and Melendez, A. J. (2005) Sphingosine kinase signalling in immune cells. Clin. Exp. Pharmacol. Physiol. 32, 153-161
-
(2005)
Clin. Exp. Pharmacol. Physiol.
, vol.32
, pp. 153-161
-
-
Kee, T.H.1
Vit, P.2
Melendez, A.J.3
-
154
-
-
38149117052
-
Sphingosine kinase signalling in immune cells: Potential as novel therapeutic targets
-
Melendez, A. J. (2008) Sphingosine kinase signalling in immune cells: potential as novel therapeutic targets. Biochim. Biophys. Acta 1784, 66-75
-
(2008)
Biochim. Biophys. Acta
, vol.1784
, pp. 66-75
-
-
Melendez, A.J.1
-
155
-
-
33744929865
-
Sphingosine kinase 1 regulates pro-inflammatory responses triggered by TNFa in primary human monocytes
-
Zhi, L., Leung, B. P. and Melendez, A. J. (2006) Sphingosine kinase 1 regulates pro-inflammatory responses triggered by TNFa in primary human monocytes. J. Cell. Physiol. 208, 109-115
-
(2006)
J. Cell. Physiol.
, vol.208
, pp. 109-115
-
-
Zhi, L.1
Leung, B.P.2
Melendez, A.J.3
-
156
-
-
0035124607
-
Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia
-
Barone, F. C., Irving, E. A., Ray, A. M., Lee, J. C., Kassis, S., Kumar, S., Badger, A. M., Legos, J. J., Erhardt, J. A., Ohlstein, E. H. et al. (2001) Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia. Med. Res. Rev. 21, 129-145
-
(2001)
Med. Res. Rev.
, vol.21
, pp. 129-145
-
-
Barone, F.C.1
Irving, E.A.2
Ray, A.M.3
Lee, J.C.4
Kassis, S.5
Kumar, S.6
Badger, A.M.7
Legos, J.J.8
Erhardt, J.A.9
Ohlstein, E.H.10
-
157
-
-
0035062840
-
MEK and p38MAPK inhibitors potentiate TNF-α induced apoptosis in U937 cells
-
Nakada, S., Kawano, T., Saito-akita, S., Iwase, S., Horiguchi-Yamada, J., Ohno, T. and Yamada, H. (2001) MEK and p38MAPK inhibitors potentiate TNF-α induced apoptosis in U937 cells. Anticancer Res. 21, 167-171
-
(2001)
Anticancer Res.
, vol.21
, pp. 167-171
-
-
Nakada, S.1
Kawano, T.2
Saito-akita, S.3
Iwase, S.4
Horiguchi-Yamada, J.5
Ohno, T.6
Yamada, H.7
-
158
-
-
2942530310
-
ERK and p38 MAPK-activated protein kinases: A family of protein kinases with diverse biological functions
-
Roux, P. P. and Blenis, J. (2004) ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol. Mol. Biol. Rev. 68, 320-344
-
(2004)
Microbiol. Mol. Biol. Rev.
, vol.68
, pp. 320-344
-
-
Roux, P.P.1
Blenis, J.2
-
159
-
-
0031916832
-
Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6
-
Enslen, H., Raingeaud, J. and Davis, R. J. (1998) Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6. J. Biol. Chem. 273, 1741-1748
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1741-1748
-
-
Enslen, H.1
Raingeaud, J.2
Davis, R.J.3
-
160
-
-
0029983730
-
The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor
-
Beyaert, R., Cuenda, A., Vanden Berghe, W., Plaisance, S., Lee, J. C., Haegeman, G., Cohen, P. and Fiers, W. (1996) The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor. EMBO J. 15, 1914-1923
-
(1996)
EMBO J.
, vol.15
, pp. 1914-1923
-
-
Beyaert, R.1
Cuenda, A.2
Vanden Berghe, W.3
Plaisance, S.4
Lee, J.C.5
Haegeman, G.6
Cohen, P.7
Fiers, W.8
-
161
-
-
0032560514
-
Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: Involvement of MEK upstream of Bad phosphorylation
-
Scheid, M. P. and Duronio, V. (1998) Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation. Proc. Natl. Acad. Sci. U. S. A. 95, 7439-7444
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 7439-7444
-
-
Scheid, M.P.1
Duronio, V.2
-
162
-
-
0034653608
-
The PI3K-PDK1 connection: More than just a road to PKB
-
Vanhaesebroeck, B. and Alessi, D. R. (2000) The PI3K-PDK1 connection: more than just a road to PKB. Biochem. J. 346, 561-576
-
(2000)
Biochem. J.
, vol.346
, pp. 561-576
-
-
Vanhaesebroeck, B.1
Alessi, D.R.2
-
163
-
-
0033517189
-
NF-κB activation by tumour necrosis factor requires the Akt serine-threonine kinase
-
Ozes, O. N., Mayo, L. D., Gustin, J. A., Pfeffer, S. R., Pfeffer, L. M. and Donner, D. B. (1999) NF-κB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 401, 82-85
-
(1999)
Nature
, vol.401
, pp. 82-85
-
-
Ozes, O.N.1
Mayo, L.D.2
Gustin, J.A.3
Pfeffer, S.R.4
Pfeffer, L.M.5
Donner, D.B.6
-
164
-
-
0034630509
-
PI3-K/AKT regulation of NF-κB signaling events in suppression of TNF-induced apoptosis
-
Burow, M. E., Weldon, C. B., Melnik, L. I., Duong, B. N., Collins-Burow, B. M., Beckman, B. S. and McLachlan, J. A. (2000) PI3-K/AKT regulation of NF-κB signaling events in suppression of TNF-induced apoptosis. Biochem. Biophys. Res. Commun. 271, 342-345
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.271
, pp. 342-345
-
-
Burow, M.E.1
Weldon, C.B.2
Melnik, L.I.3
Duong, B.N.4
Collins-Burow, B.M.5
Beckman, B.S.6
McLachlan, J.A.7
-
165
-
-
34548187466
-
Distinctive role of integrin-mediated adhesion in TNF-induced PKB/Akt and NF-κB activation and endothelial cell survival
-
Bieler, G., Hasmim, M., Monnier, Y., Imaizumi, N., Ameyar, M., Bamat, J., Ponsonnet, L., Chouaib, S., Grell, M., Goodman, S. L. et al. (2007) Distinctive role of integrin-mediated adhesion in TNF-induced PKB/Akt and NF-κB activation and endothelial cell survival. Oncogene 26, 5722-5732
-
(2007)
Oncogene
, vol.26
, pp. 5722-5732
-
-
Bieler, G.1
Hasmim, M.2
Monnier, Y.3
Imaizumi, N.4
Ameyar, M.5
Bamat, J.6
Ponsonnet, L.7
Chouaib, S.8
Grell, M.9
Goodman, S.L.10
-
166
-
-
0032549670
-
Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals
-
Widmann, C., Gibson, S. and Johnson, G. L. (1998) Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals. J. Biol. Chem. 273, 7141-7147
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 7141-7147
-
-
Widmann, C.1
Gibson, S.2
Johnson, G.L.3
-
167
-
-
0034607914
-
Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473
-
Schubert, K. M., Scheid, M. P. and Duronio, V. (2000) Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473. J. Biol. Chem. 275, 13330-13335
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 13330-13335
-
-
Schubert, K.M.1
Scheid, M.P.2
Duronio, V.3
-
168
-
-
0034816711
-
Ceramide induces the dephosphorylation and inhibition of constitutively activated Akt in PTEN negative U87mg cells
-
Zinda, M. J., Vlahos, C. J. and Lai, M. T. (2001) Ceramide induces the dephosphorylation and inhibition of constitutively activated Akt in PTEN negative U87mg cells. Biochem. Biophys. Res. Commun. 280, 1107-1115
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.280
, pp. 1107-1115
-
-
Zinda, M.J.1
Vlahos, C.J.2
Lai, M.T.3
-
169
-
-
0034724668
-
Cyclic nucleotides suppress tumor necrosis factor α-mediated apoptosis by Inhibiting caspase activation and cytochrome c release in primary hepatocytes via a mechanism independent of Akt activation
-
Li, J., Yang, S. and Billiar, T. R. (2000) Cyclic nucleotides suppress tumor necrosis factor α-mediated apoptosis by Inhibiting caspase activation and cytochrome c release in primary hepatocytes via a mechanism independent of Akt activation. J. Biol. Chem. 275, 13026-13034
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 13026-13034
-
-
Li, J.1
Yang, S.2
Billiar, T.R.3
-
170
-
-
0013202857
-
Pharmacological inhibitors of the ERK signaling pathway: Application as anticancer drugs
-
Kohno, M. and Pouyssegur, J. (2003) Pharmacological inhibitors of the ERK signaling pathway: application as anticancer drugs. Prog. Cell Cycle Res. 5, 219-224
-
(2003)
Prog. Cell Cycle Res.
, vol.5
, pp. 219-224
-
-
Kohno, M.1
Pouyssegur, J.2
-
171
-
-
0035413618
-
MAP kinases
-
Chen, Z., Gibson, T. B., Robinson, F., Silvestro, L., Pearson, G., Xu, B., Wright, A., Vanderbilt, C. and Cobb, M. H. (2001) MAP kinases. Chem. Rev. 101, 2449-2476
-
(2001)
Chem. Rev.
, vol.101
, pp. 2449-2476
-
-
Chen, Z.1
Gibson, T.B.2
Robinson, F.3
Silvestro, L.4
Pearson, G.5
Xu, B.6
Wright, A.7
Vanderbilt, C.8
Cobb, M.H.9
-
172
-
-
0027076644
-
Tumor necrosis factor stimulates multiple serine/threonine protein kinases in Swiss 3T3 and L929 cells. Implication of casein kinase-2 and extracellular signal-regulated kinases in the tumor necrosis factor signal transduction pathway
-
Van Lint, J., Agostinis, P., Vandevoorde, V., Haegeman, G., Fiers, W., Merlevede, W. and Vandenheede, J. R. (1992) Tumor necrosis factor stimulates multiple serine/threonine protein kinases in Swiss 3T3 and L929 cells. Implication of casein kinase-2 and extracellular signal-regulated kinases in the tumor necrosis factor signal transduction pathway. J. Biol. Chem. 267, 25916-25921
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 25916-25921
-
-
Van Lint, J.1
Agostinis, P.2
Vandevoorde, V.3
Haegeman, G.4
Fiers, W.5
Merlevede, W.6
Vandenheede, J.R.7
-
173
-
-
0029948396
-
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
-
Cuvillier, O., Pirianov, G., Kleuser, B., Vanek, P. G., Coso, O. A., Gutkind, S. and Spiegel, S. (1996) Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature 381, 800-803
-
(1996)
Nature
, vol.381
, pp. 800-803
-
-
Cuvillier, O.1
Pirianov, G.2
Kleuser, B.3
Vanek, P.G.4
Coso, O.A.5
Gutkind, S.6
Spiegel, S.7
-
174
-
-
0035154914
-
MAP kinase activation in macrophages
-
Rao, K. M. (2001) MAP kinase activation in macrophages. J. Leukocyte Biol. 69, 3-10
-
(2001)
J. Leukocyte Biol.
, vol.69
, pp. 3-10
-
-
Rao, K.M.1
-
175
-
-
0030910313
-
MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase
-
Schievella, A. R., Chen, J. H., Graham, J. R. and Lin, L. L. (1997) MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase. J. Biol. Chem. 272, 12069-12075
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12069-12075
-
-
Schievella, A.R.1
Chen, J.H.2
Graham, J.R.3
Lin, L.L.4
-
176
-
-
0033532626
-
Identification of Grb2 as a novel binding partner of tumor necrosis factor (TNF) receptor I
-
Hildt, E. and Oess, S. (1999) Identification of Grb2 as a novel binding partner of tumor necrosis factor (TNF) receptor I. J. Exp. Med. 189, 1707-1714
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1707-1714
-
-
Hildt, E.1
Oess, S.2
-
177
-
-
0030595340
-
FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase
-
Adam-Klages, S., Adam, D., Wiegmann, K., Struve, S., Kolanus, W., Schneider-Mergener, J. and Kranke, M. (1996) FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase. Cell 86, 937-947
-
(1996)
Cell
, vol.86
, pp. 937-947
-
-
Adam-Klages, S.1
Adam, D.2
Wiegmann, K.3
Struve, S.4
Kolanus, W.5
Schneider-Mergener, J.6
Kranke, M.7
-
178
-
-
0033522399
-
Impaired neutral sphingomyelinase activation and cutaneous barrier repair in FAN-deficient mice
-
Kreder, D., Krut, O., Adam-Klages, S., Wiegmann, K., Scherer, G., Plitz, T., Jensen, J. M., Proksch, E., Steinmann, J., Pfeffer, K. and Kranke, M. (1999) Impaired neutral sphingomyelinase activation and cutaneous barrier repair in FAN-deficient mice. EMBO J. 18, 2472-2479
-
(1999)
EMBO J.
, vol.18
, pp. 2472-2479
-
-
Kreder, D.1
Krut, O.2
Adam-Klages, S.3
Wiegmann, K.4
Scherer, G.5
Plitz, T.6
Jensen, J.M.7
Proksch, E.8
Steinmann, J.9
Pfeffer, K.10
Kranke, M.11
-
179
-
-
0031779350
-
Distinct adapter proteins mediate acid versus neutral sphingomyelinase activation through the p55 receptor for tumor necrosis factor
-
Adam-Klages, S., Schwandner, R., Adam, D., Kreder, D., Bernardo, K. and Kronke, M. (1998) Distinct adapter proteins mediate acid versus neutral sphingomyelinase activation through the p55 receptor for tumor necrosis factor. J. Leukocyte Biol. 63, 678-682
-
(1998)
J. Leukocyte Biol.
, vol.63
, pp. 678-682
-
-
Adam-Klages, S.1
Schwandner, R.2
Adam, D.3
Kreder, D.4
Bernardo, K.5
Kronke, M.6
-
180
-
-
0027959655
-
Involvement of the tumor necrosis factor receptor p75 in mediating cytotoxicity and gene regulating activities
-
Medvedev, A. E., Sundan, A. and Espevik, T. (1994) Involvement of the tumor necrosis factor receptor p75 in mediating cytotoxicity and gene regulating activities. Eur. J. Immunol. 24, 2842-2849
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 2842-2849
-
-
Medvedev, A.E.1
Sundan, A.2
Espevik, T.3
-
181
-
-
0033152828
-
Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: A role for TNF-Rl activation by endogenous membrane-anchored TNF
-
Grell, M., Zimmermann, G., Gottfried, E., Chen, C. M., Grunwald, U., Huang, D. C., Wu Lee, Y. H., Durkop, H., Engelmann, H., Scheurich, P. et al. (1999) Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-Rl activation by endogenous membrane-anchored TNF. EMBO J. 18, 3034-3043
-
(1999)
EMBO J.
, vol.18
, pp. 3034-3043
-
-
Grell, M.1
Zimmermann, G.2
Gottfried, E.3
Chen, C.M.4
Grunwald, U.5
Huang, D.C.6
Wu Lee, Y.H.7
Durkop, H.8
Engelmann, H.9
Scheurich, P.10
-
182
-
-
0032530378
-
TNFR80-dependent enhancement of TNFR60-induced cell death is mediated by TNFR-associated factor 2 and is specific for TNFR60
-
Weiss, T., Grell, M., Siemienski, K., Muhlenbeck, F., Durkop, H., Pfizenmaier, K., Scheurich, P. and Wajant, H. (1998) TNFR80-dependent enhancement of TNFR60-induced cell death is mediated by TNFR-associated factor 2 and is specific for TNFR60. J. Immunol. 161, 3136-3142
-
(1998)
J. Immunol.
, vol.161
, pp. 3136-3142
-
-
Weiss, T.1
Grell, M.2
Siemienski, K.3
Muhlenbeck, F.4
Durkop, H.5
Pfizenmaier, K.6
Scheurich, P.7
Wajant, H.8
-
183
-
-
0027301244
-
Ligand passing: The 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor
-
Tartaglia, L. A., Pennica, D. and Goeddel, D. V. (1993) Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor. J. Biol. Chem. 268, 18542-18548
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 18542-18548
-
-
Tartaglia, L.A.1
Pennica, D.2
Goeddel, D.V.3
-
184
-
-
0029038912
-
A protein related to a proteasomal subunit binds to the intracellular domain of the p55 TNF receptor upstream to its 'death domain'
-
Boldin, M. P., Mett, I. L. and Wallach, D. (1995) A protein related to a proteasomal subunit binds to the intracellular domain of the p55 TNF receptor upstream to its 'death domain'. FEBS Lett. 367, 39-44
-
(1995)
FEBS Lett.
, vol.367
, pp. 39-44
-
-
Boldin, M.P.1
Mett, I.L.2
Wallach, D.3
-
185
-
-
0028954475
-
Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor
-
Song, H. Y., Dunbar, J. D., Zhang, Y. X., Guo, D. and Donner, D. B. (1995) Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor. J. Biol. Chem. 270, 3574-3581
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 3574-3581
-
-
Song, H.Y.1
Dunbar, J.D.2
Zhang, Y.X.3
Guo, D.4
Donner, D.B.5
-
186
-
-
0031135534
-
Two-hybrid cloning of a gene encoding TNF receptor-associated protein 2, a protein that interacts with the intracellular domain of the type 1 TNF receptor: Identity with subunit 2 of the 26S protease
-
Dunbar, J. D., Song, H. Y., Guo, D., Wu, L. W. and Donner, D. B. (1997) Two-hybrid cloning of a gene encoding TNF receptor-associated protein 2, a protein that interacts with the intracellular domain of the type 1 TNF receptor: identity with subunit 2 of the 26S protease. J. Immunol. 158, 4252-4259
-
(1997)
J. Immunol.
, vol.158
, pp. 4252-4259
-
-
Dunbar, J.D.1
Song, H.Y.2
Guo, D.3
Wu, L.W.4
Donner, D.B.5
-
187
-
-
0034603178
-
The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties
-
Felts, S. J., Owen, B. A., Nguyen, P., Trepel, J., Donner, D. B. and Toft, D. O. (2000) The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties. J. Biol. Chem. 275, 3305-3312
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 3305-3312
-
-
Felts, S.J.1
Owen, B.A.2
Nguyen, P.3
Trepel, J.4
Donner, D.B.5
Toft, D.O.6
-
188
-
-
0029760873
-
A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock
-
Chen, C. F., Chen, Y., Dai, K., Chen, P. L., Riley, D. J. and Lee, W. H. (1996) A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock. Mol. Cell. Biol. 16, 4691-4699
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4691-4699
-
-
Chen, C.F.1
Chen, Y.2
Dai, K.3
Chen, P.L.4
Riley, D.J.5
Lee, W.H.6
-
189
-
-
0031662251
-
BRE: A modulator of TNF-α action
-
Gu, C., Castellino, A., Chan, J. Y. and Chao, M. V. (1998) BRE: a modulator of TNF-α action. FASEB J. 12, 1101-1108
-
(1998)
FASEB J.
, vol.12
, pp. 1101-1108
-
-
Gu, C.1
Castellino, A.2
Chan, J.Y.3
Chao, M.V.4
-
190
-
-
0031047829
-
A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase
-
Castellino, A. M., Parker, G. J., Boronenkov, I. V., Anderson, R. A. and Chao, M. V. (1997) A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase. J. Biol. Chem. 272, 5861-5870
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 5861-5870
-
-
Castellino, A.M.1
Parker, G.J.2
Boronenkov, I.V.3
Anderson, R.A.4
Chao, M.V.5
-
191
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel, D. P. (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
192
-
-
33747608638
-
NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
-
Taganov, K. D., Boldin, M. P., Chang, K. J. and Baltimore, D. (2006) NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc. Natl. Acad. Sci. U. S. A. 103, 12481-12486
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 12481-12486
-
-
Taganov, K.D.1
Boldin, M.P.2
Chang, K.J.3
Baltimore, D.4
-
193
-
-
33846845071
-
MicroRNA-155 is induced during the macrophage inflammatory response
-
O'Connell, R. M., Taganov, K. D., Boldin, M. P., Cheng, G. and Baltimore, D. (2007) MicroRNA-155 is induced during the macrophage inflammatory response. Proc. Natl. Acad. Sci. U.S.A. 104, 1604-1609
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 1604-1609
-
-
O'Connell, R.M.1
Taganov, K.D.2
Boldin, M.P.3
Cheng, G.4
Baltimore, D.5
-
194
-
-
34247584465
-
Requirement of bic/microRNA-155 for normal immune function
-
Rodriguez, A., Vigorito, E., Clare, S., Warren, M. V., Couttet, P., Soond, D. R., van Dongen, S., Grocock, R. J., Das, P. P., Miska, E. A. et al. (2007) Requirement of bic/microRNA-155 for normal immune function. Science 316, 608-611
-
(2007)
Science
, vol.316
, pp. 608-611
-
-
Rodriguez, A.1
Vigorito, E.2
Clare, S.3
Warren, M.V.4
Couttet, P.5
Soond, D.R.6
Van Dongen, S.7
Grocock, R.J.8
Das, P.P.9
Miska, E.A.10
-
195
-
-
38049030287
-
Modulation of miR-155 and miR-125b levels following lipopolysaccharide/ TNF-α stimulation and their possible roles in regulating the response to endotoxin shock
-
Tili, E., Michaille, J. J., Cimino, A., Costinean, S., Dumitru, C. D., Adair, B., Fabbri, M., Alder, H., Liu, C. G., Calin, G. A. and Croce, C. M. (2007) Modulation of miR-155 and miR-125b levels following lipopolysaccharide/ TNF-α stimulation and their possible roles in regulating the response to endotoxin shock. J. Immunol. 179, 5082-5089
-
(2007)
J. Immunol.
, vol.179
, pp. 5082-5089
-
-
Tili, E.1
Michaille, J.J.2
Cimino, A.3
Costinean, S.4
Dumitru, C.D.5
Adair, B.6
Fabbri, M.7
Alder, H.8
Liu, C.G.9
Calin, G.A.10
Croce, C.M.11
-
196
-
-
73949113629
-
Cutting edge: TNF-induced microRNAs regulate TNF-induced expression of E-selectin and intercellular adhesion molecule-1 on human endothelial cells: Feedback control of inflammation
-
Suarez, Y., Wang, C., Manes, T. D. and Pober, J. S. (2010) Cutting edge: TNF-induced microRNAs regulate TNF-induced expression of E-selectin and intercellular adhesion molecule-1 on human endothelial cells: feedback control of inflammation. J. Immunol. 184, 21-25
-
(2010)
J. Immunol.
, vol.184
, pp. 21-25
-
-
Suarez, Y.1
Wang, C.2
Manes, T.D.3
Pober, J.S.4
-
197
-
-
40349098262
-
Interactions between TNF and GnRH
-
MacEwan, D. J. (2008) Interactions between TNF and GnRH. Neurochem. Res. 33, 678-682
-
(2008)
Neurochem. Res.
, vol.33
, pp. 678-682
-
-
MacEwan, D.J.1
-
198
-
-
38549102077
-
TNF-mediated inflammatory disease
-
Bradley, J. R. (2008) TNF-mediated inflammatory disease. J. Pathol. 214, 149-160
-
(2008)
J. Pathol.
, vol.214
, pp. 149-160
-
-
Bradley, J.R.1
-
199
-
-
35448935612
-
Biological and clinical effects of anti-TNFa treatment
-
Valesini, G., Iannuccelli, C., Marocchi, E., Pascoli, L., Scalzi, V. and Di Franco, M. (2007) Biological and clinical effects of anti-TNFa treatment. Autoimmun. Rev. 7, 35-41
-
(2007)
Autoimmun. Rev.
, vol.7
, pp. 35-41
-
-
Valesini, G.1
Iannuccelli, C.2
Marocchi, E.3
Pascoli, L.4
Scalzi, V.5
Di Franco, M.6
-
200
-
-
38549176118
-
Tumor necrosis factor antagonist mechanisms of action: A comprehensive review
-
Tracey, D., Klareskog, L., Sasso, E. H., Salfeld, J. G. and Tak, P. P. (2008) Tumor necrosis factor antagonist mechanisms of action: a comprehensive review. Pharmacol. Ther. 117, 244-279
-
(2008)
Pharmacol. Ther.
, vol.117
, pp. 244-279
-
-
Tracey, D.1
Klareskog, L.2
Sasso, E.H.3
Salfeld, J.G.4
Tak, P.P.5
-
201
-
-
73649133630
-
Novel TACE inhibitors in drug discovery: A review of patented compounds
-
Murumkar, P. R., DasGupta, S., Chandani, S. R., Giridhar, R. and Yadav, M. R. (2010) Novel TACE inhibitors in drug discovery: a review of patented compounds. Expert Opin. Ther. Pat. 20, 31-57
-
(2010)
Expert Opin. Ther. Pat.
, vol.20
, pp. 31-57
-
-
Murumkar, P.R.1
DasGupta, S.2
Chandani, S.R.3
Giridhar, R.4
Yadav, M.R.5
-
202
-
-
75749115504
-
What have we learnt from targeted anti-TNF therapy?
-
Feldmann, M., Williams, R. O. and Paleolog, E. (2010) What have we learnt from targeted anti-TNF therapy? Ann. Rheum. Dis. 69 (Suppl. 1), i97-i99
-
(2010)
Ann. Rheum. Dis.
, vol.69
, Issue.SUPPL. 1
-
-
Feldmann, M.1
Williams, R.O.2
Paleolog, E.3
-
203
-
-
0027297663
-
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L monocytogenes infection
-
Pfeffer, K., Matsuyama, T., Kundig, T. M., Wakeham, A., Kishihara, K., Shahinian, A., Wiegmann, K., Ohashi, P. S., Kronke, M. and Mak, T. W. (1993) Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L monocytogenes infection. Cell 73, 457-467
-
(1993)
Cell
, vol.73
, pp. 457-467
-
-
Pfeffer, K.1
Matsuyama, T.2
Kundig, T.M.3
Wakeham, A.4
Kishihara, K.5
Shahinian, A.6
Wiegmann, K.7
Ohashi, P.S.8
Kronke, M.9
Mak, T.W.10
-
204
-
-
0036569910
-
TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection
-
Roach, D. R., Bean, A. G., Demangel, C., France, M. P., Briscoe, H. and Britton, W. J. (2002) TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection. J. Immunol. 168, 4620-4627
-
(2002)
J. Immunol.
, vol.168
, pp. 4620-4627
-
-
Roach, D.R.1
Bean, A.G.2
Demangel, C.3
France, M.P.4
Briscoe, H.5
Britton, W.J.6
-
205
-
-
22544436130
-
Reactivation of latent granulomatous infections by infliximab
-
Wallis, R. S., Broder, M., Wong, J., Lee, A. and Hoq, L. (2005) Reactivation of latent granulomatous infections by infliximab. Clin. Infect. Dis. 41 (Suppl. 3), S194-S198
-
(2005)
Clin. Infect. Dis.
, vol.41
, Issue.SUPPL. 3
-
-
Wallis, R.S.1
Broder, M.2
Wong, J.3
Lee, A.4
Hoq, L.5
-
206
-
-
19244362897
-
The effect of a monoclonal antibody to tumor necrosis factor on survival from childhood cerebral malaria
-
Van Hensbroek, M. B., Palmer, A., Onyiorah, E., Schneider, G., Jaffar, S., Dolan, G., Memming, H., Frenkel, J., Enwere, G., Bennett, S., Kwiatkowski, D. and Greenwood, B. (1996) The effect of a monoclonal antibody to tumor necrosis factor on survival from childhood cerebral malaria. J. Infect. Dis. 174, 1091-1097
-
(1996)
J. Infect. Dis.
, vol.174
, pp. 1091-1097
-
-
Van Hensbroek, M.B.1
Palmer, A.2
Onyiorah, E.3
Schneider, G.4
Jaffar, S.5
Dolan, G.6
Memming, H.7
Frenkel, J.8
Enwere, G.9
Bennett, S.10
Kwiatkowski, D.11
Greenwood, B.12
-
207
-
-
0142058174
-
Anti-TNF-α therapies: The next generation
-
Palladino, M. A., Bahjat, F. R., Theodorakis, E. A. and Moldawer, L. L. (2003) Anti-TNF-α therapies: the next generation. Nat. Rev. Drug Discov. 2, 736-746
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 736-746
-
-
Palladino, M.A.1
Bahjat, F.R.2
Theodorakis, E.A.3
Moldawer, L.L.4
-
208
-
-
33745679123
-
Targeting signal transduction as a strategy to treat inflammatory diseases
-
O'Neill, L. A. (2006) Targeting signal transduction as a strategy to treat inflammatory diseases. Nat. Rev. Drug Discov. 5, 549-563
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 549-563
-
-
O'Neill, L.A.1
|