Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2- dependent pathway

Science

Volumn 275, Issue 5297, 1997, Pages 200-203

  Natoli, Gioacchino ^a   Costanzo, Antonio ^a   Ianni, Angelo ^a   Templeton, Dennis J ^b   Woodgett, James R ^c   Balsano, Clara ^d   Levrero, Massimo ^a  

^a POLICLINICO UMBERTO I   (Italy)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c PRINCESS MARGARET HOSPITAL   (Canada)

^d UNIVERSITY OF L'AQUILA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; COMPLEMENTARY DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MONOCLONAL ANTIBODY; PROTEIN KINASE; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL DEATH; CELL LINE; CYTOTOXICITY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; EXPRESSION VECTOR; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ACETYLCYSTEINE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; APOPTOSIS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CARRIER PROTEINS; CELL LINE; DACTINOMYCIN; ENZYME ACTIVATION; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; FREE RADICAL SCAVENGERS; HELA CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; REACTIVE OXYGEN SPECIES; RECEPTORS, TUMOR NECROSIS FACTOR; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 1; TNF RECEPTOR-ASSOCIATED FACTOR 2; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031013545     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.275.5297.200     Document Type: Article

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