-
1
-
-
0030271387
-
NF-κB: Ten years after
-
Baeuerle, P. A., and D. Baltimore. 1996. NF-κB: ten years after. Cell 87:13-20.
-
(1996)
Cell
, vol.87
, pp. 13-20
-
-
Baeuerle, P.A.1
Baltimore, D.2
-
2
-
-
0029874138
-
The NF-κB and IκB proteins - New discoveries and insights
-
Baldwin, A. S. 1996. The NF-κB and IκB proteins - new discoveries and insights. Annu. Rev. Immunnl. 14:649-683.
-
(1996)
Annu. Rev. Immunnl.
, vol.14
, pp. 649-683
-
-
Baldwin, A.S.1
-
3
-
-
0030615201
-
Nuclear factor-κB: A pivotal transcription factor in chronic inflammatory diseases
-
Barnes, P. J., and M. Karin. 1997. Nuclear factor-κB: a pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 336:1066-1071.
-
(1997)
N. Engl. J. Med.
, vol.336
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
4
-
-
0033563101
-
Signaling by proinflammatory cytokines: Oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain
-
Baud, V., Z. G. Liu, B. Bennett, N. Suzuki, Y. Xia, and M. Karin. 1999. Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain. Genes Dev. 13:1297-1308.
-
(1999)
Genes Dev.
, vol.13
, pp. 1297-1308
-
-
Baud, V.1
Liu, Z.G.2
Bennett, B.3
Suzuki, N.4
Xia, Y.5
Karin, M.6
-
5
-
-
0033725155
-
The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation
-
Devin, A., A. Cook, Y. Lin, Y. Rodriguez, M. Kelliher, and Z. G. Liu. 2000. The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation. Immunity 12:419-429.
-
(2000)
Immunity
, vol.12
, pp. 419-429
-
-
Devin, A.1
Cook, A.2
Lin, Y.3
Rodriguez, Y.4
Kelliher, M.5
Liu, Z.G.6
-
6
-
-
0030610362
-
A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
-
DiDonato, J. A., M. Hayakawa, D. M. Rothwarf, E. Zandi, and M. Karin. 1997. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature 388:548-554.
-
(1997)
Nature
, vol.388
, pp. 548-554
-
-
DiDonato, J.A.1
Hayakawa, M.2
Rothwarf, D.M.3
Zandi, E.4
Karin, M.5
-
7
-
-
0003448569
-
-
Cold Spring Harbor Laboratory Press. Cold Spring Harbor, N. Y.
-
Harlow, E., and D. Lane. 1999. Using antibodies: a laboratory manual, p. 323-325. Cold Spring Harbor Laboratory Press. Cold Spring Harbor, N. Y.
-
(1999)
Using Antibodies: A Laboratory Manual
, pp. 323-325
-
-
Harlow, E.1
Lane, D.2
-
8
-
-
0029007855
-
The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation
-
Hsu, H., J. Xiong, and D. V. Goeddel. 1995. The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation. Cell 81:495-504.
-
(1995)
Cell
, vol.81
, pp. 495-504
-
-
Hsu, H.1
Xiong, J.2
Goeddel, D.V.3
-
9
-
-
0030032106
-
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor-1 signal transduction pathways
-
Hsu, H., H. B. Shu, M. P. Pan, and D. V. Goeddel. 1996. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor-1 signal transduction pathways. Cell 84:299-308.
-
(1996)
Cell
, vol.84
, pp. 299-308
-
-
Hsu, H.1
Shu, H.B.2
Pan, M.P.3
Goeddel, D.V.4
-
10
-
-
0029949257
-
TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex
-
Hsu, H., J. Huang, H. B. Shu, V. Baichwal, and D. V. Goeddel. 1996. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 4:387-396.
-
(1996)
Immunity
, vol.4
, pp. 387-396
-
-
Hsu, H.1
Huang, J.2
Shu, H.B.3
Baichwal, V.4
Goeddel, D.V.5
-
11
-
-
0033537767
-
Abnormal morphogenesis but intact IKK activation in mice lacking the IKK alpha subunit of IkappaB kinase
-
Hu, Y., V. Baud, M. Delhase, P. Zhang, T. Deerinck, M. Ellisman, R. Johnson, M. Karin. 1999. Abnormal morphogenesis but intact IKK activation in mice lacking the IKK alpha subunit of IkappaB kinase. Science 284:316-320.
-
(1999)
Science
, vol.284
, pp. 316-320
-
-
Hu, Y.1
Baud, V.2
Delhase, M.3
Zhang, P.4
Deerinck, T.5
Ellisman, M.6
Johnson, R.7
Karin, M.8
-
12
-
-
0033600604
-
The beginning of the end: IκB kinase (IKK) and NF-κB activation
-
Karin, M. 1999. The beginning of the end: IκB kinase (IKK) and NF-κB activation. J. Biol. Chem. 274:27339-27342.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 27339-27342
-
-
Karin, M.1
-
13
-
-
0032033132
-
The death domain kinase RIP mediates the TNF-induced NF-κB signal
-
Kelliher, M. A., S. Grimm, Y. Ishida, F. Kuo, B. Z. Stanger, and P. Leder. 1998. The death domain kinase RIP mediates the TNF-induced NF-κB signal. Immunity 8:297-303.
-
(1998)
Immunity
, vol.8
, pp. 297-303
-
-
Kelliher, M.A.1
Grimm, S.2
Ishida, Y.3
Kuo, F.4
Stanger, B.Z.5
Leder, P.6
-
14
-
-
0034614656
-
Physical and functional interaction of filamin (actin-binding protein-280) and tumor necrosis factor receptor-associated factor 2
-
Leonardi, A., H. Ellinger-Ziegelbauer, G. Franzoso, K. Brown, and U. Siebenlist. 2000. Physical and functional interaction of filamin (actin-binding protein-280) and tumor necrosis factor receptor-associated factor 2. J Biol Chem. 275:271-278.
-
(2000)
J Biol Chem.
, vol.275
, pp. 271-278
-
-
Leonardi, A.1
Ellinger-Ziegelbauer, H.2
Franzoso, G.3
Brown, K.4
Siebenlist, U.5
-
15
-
-
0033537739
-
Severe liver degeneration in mice lacking the IkappaB kinase 2 gene
-
Li, Q., D. Van Antwerp, F. Mercurio, K. F. Lee, and I. M. Verma. 1999. Severe liver degeneration in mice lacking the IkappaB kinase 2 gene. Science 284:321-325.
-
(1999)
Science
, vol.284
, pp. 321-325
-
-
Li, Q.1
Van Antwerp, D.2
Mercurio, F.3
Lee, K.F.4
Verma, I.M.5
-
16
-
-
0034661272
-
Complete lack of NF-kappaB activity in IKK1 and IKK2 double-deficient mice: Additional defect in neurulation
-
Li, Q., G. Estepa, S. Memet, A. Israel, and I. M. Verma. 2000. Complete lack of NF-kappaB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation. Genes Dev. 14:1729-1733.
-
(2000)
Genes Dev.
, vol.14
, pp. 1729-1733
-
-
Li, Q.1
Estepa, G.2
Memet, S.3
Israel, A.4
Verma, I.M.5
-
17
-
-
0033563227
-
IKK1-deficient mice exhibit abnormal development of skin and skeleton
-
Li, Q., Q. Lu, J. Y. Hwang, D. Buscher, K. F. Lee, J. C. Izpisua-Belmonte, and I. M. Verma. 1999. IKK1-deficient mice exhibit abnormal development of skin and skeleton. Genes Dev. 13:1322-1328.
-
(1999)
Genes Dev.
, vol.13
, pp. 1322-1328
-
-
Li, Q.1
Lu, Q.2
Hwang, J.Y.3
Buscher, D.4
Lee, K.F.5
Izpisua-Belmonte, J.C.6
Verma, I.M.7
-
18
-
-
0033532386
-
The IKKbeta subunit of IκB kinase (IKK) is essential for nuclear factor κB activation and prevention of apoptosis
-
Li, Z. W., W. Chu, Y. Hu, M. Delhase, T. Deerinck, M. Ellisman, R. Johnson, and M. Karin. 1999. The IKKbeta subunit of IκB kinase (IKK) is essential for nuclear factor κB activation and prevention of apoptosis. J. Exp. Med. 189:1839-1845.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1839-1845
-
-
Li, Z.W.1
Chu, W.2
Hu, Y.3
Delhase, M.4
Deerinck, T.5
Ellisman, M.6
Johnson, R.7
Karin, M.8
-
19
-
-
0033214236
-
Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
-
Lin, Y., A. Devin, Y. Rodriguez, and Z. C. Liu. 1999. Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev. 13:2514-2525.
-
(1999)
Genes Dev.
, vol.13
, pp. 2514-2525
-
-
Lin, Y.1
Devin, A.2
Rodriguez, Y.3
Liu, Z.C.4
-
20
-
-
0030298294
-
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
-
Liu, Z. G., H., Hsu, D. V., Goeddel, and M. Karin. 1996. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell 87:565-576.
-
(1996)
Cell
, vol.87
, pp. 565-576
-
-
Liu, Z.G.1
Hsu, H.2
Goeddel, D.V.3
Karin, M.4
-
21
-
-
0033634663
-
Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti
-
Makris, C., V. L., Godfrey, G., Krahn-Senftleben, T., Takahashi, J. L., Roberts, T., Schwarz, L., Feng, R. S., Johnson, and M. Karin. 2000. Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti. Mol. Cell 5:969-979.
-
(2000)
Mol. Cell
, vol.5
, pp. 969-979
-
-
Makris, C.1
Godfrey, V.L.2
Krahn-Senftleben, G.3
Takahashi, T.4
Roberts, J.L.5
Schwarz, T.6
Feng, L.7
Johnson, R.S.8
Karin, M.9
-
22
-
-
0034284715
-
Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex
-
May, M. J., F., D'Acquisto, L. A., Madge, J., Glockner, J. S., Pober, and S. Ghosh. 2000. Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex. Science 289:1550-1554.
-
(2000)
Science
, vol.289
, pp. 1550-1554
-
-
May, M.J.1
D'Acquisto, F.2
Madge, L.A.3
Glockner, J.4
Pober, J.S.5
Ghosh, S.6
-
23
-
-
0030685825
-
IKK-1 and IKK-2: Cytokine-activated IκB kinases essential for NF-κB activation
-
Mercurio, F., H., Zhu, B. W., Murray, A., Shevchenko, B. L., Bennett, J., Li, D. B, Young, M., Barbosa, M., Mann, A., Manning, and A. Rao. 1997. IKK-1 and IKK-2: cytokine-activated IκB kinases essential for NF-κB activation. Science 278:860-866.
-
(1997)
Science
, vol.278
, pp. 860-866
-
-
Mercurio, F.1
Zhu, H.2
Murray, B.W.3
Shevchenko, A.4
Bennett, B.L.5
Li, J.6
Young, D.B.7
Barbosa, M.8
Mann, M.9
Manning, A.10
Rao, A.11
-
25
-
-
0033621618
-
Activation of the heterodimeric IκB kinase α (IKKα)-IKKβ complex is directional: IKKα regulates IKKβ under both basal and stimulated conditions
-
O'Mahony, A., X., Lin, R., Geleziunas, and W. C. Greene. 2000. Activation of the heterodimeric IκB kinase α (IKKα)-IKKβ complex is directional: IKKα regulates IKKβ under both basal and stimulated conditions. Mol. Cell. Biol. 20:1170-1178.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1170-1178
-
-
O'Mahony, A.1
Lin, X.2
Geleziunas, R.3
Greene, W.C.4
-
26
-
-
0031586174
-
Identification and characterization of an IkappaB kinase
-
Regnier, C. H., H. Y. Song, X. Gao, D. V. Goeddel, Z. Cao, and M. Rothe. 1997. Identification and characterization of an IkappaB kinase. Cell 90:373-383.
-
(1997)
Cell
, vol.90
, pp. 373-383
-
-
Regnier, C.H.1
Song, H.Y.2
Gao, X.3
Goeddel, D.V.4
Cao, Z.5
Rothe, M.6
-
27
-
-
0028124428
-
A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor
-
Rothe, M., S. C., Wong, W. J., Henzel, and D. V. Goeddel. 1994 A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor. Cell 78:681-692.
-
(1994)
Cell
, vol.78
, pp. 681-692
-
-
Rothe, M.1
Wong, S.C.2
Henzel, W.J.3
Goeddel, D.V.4
-
28
-
-
0028978626
-
TRAF2-mediated activation of NF-κB by TNF receptor 2 and CD40
-
Rothe, M., V., Sarma, V. M., Dixit, and D. V. Goeddel. 1995. TRAF2-mediated activation of NF-κB by TNF receptor 2 and CD40. Science 269: 1424-1427.
-
(1995)
Science
, vol.269
, pp. 1424-1427
-
-
Rothe, M.1
Sarma, V.2
Dixit, V.M.3
Goeddel, D.V.4
-
29
-
-
0032541657
-
IKK-gamma is an essential regulatory subunit of the IκB kinase complex
-
Rothwarf, D. M., E., Zandi, G., Natoli, and M. Karin. 1998. IKK-gamma is an essential regulatory subunit of the IκB kinase complex. Nature 395:297-300.
-
(1998)
Nature
, vol.395
, pp. 297-300
-
-
Rothwarf, D.M.1
Zandi, E.2
Natoli, G.3
Karin, M.4
-
30
-
-
0034175632
-
Severe liver degeneration and lack of NF-κB activation in NEMO/IKKgamma-deflcient mice
-
Rudolph, D., W. C., Yen, A., Wakeham, B., Rudolph, D., Nallainathan, J., Potter, A. J., Elia, and T. W. Mak. 2000. Severe liver degeneration and lack of NF-κB activation in NEMO/IKKgamma-deflcient mice. Genes Dev. 14: 854-862.
-
(2000)
Genes Dev.
, vol.14
, pp. 854-862
-
-
Rudolph, D.1
Yen, W.C.2
Wakeham, A.3
Rudolph, B.4
Nallainathan, D.5
Potter, J.6
Elia, A.J.7
Mak, T.W.8
-
31
-
-
0033638970
-
NEMO/IKK gamma-deficient mice model incontinentia pigmenti
-
Schmidt-Supprian, M., W., Bloch, G., Courtois, K., Addicks, A., Israel, K., Rajewsky, and M. Pasparakis. 2000. NEMO/IKK gamma-deficient mice model incontinentia pigmenti. Mol. Cell 5:981-992.
-
(2000)
Mol. Cell
, vol.5
, pp. 981-992
-
-
Schmidt-Supprian, M.1
Bloch, W.2
Courtois, G.3
Addicks, K.4
Israel, A.5
Rajewsky, K.6
Pasparakis, M.7
-
32
-
-
0028170816
-
Structure, regulation and function of NF-κB
-
Siebenlist, U., G., Franzoso, and K. Brown. 1994. Structure, regulation and function of NF-κB. Annu. Rev. Cell Biol. 10:405-455.
-
(1994)
Annu. Rev. Cell Biol.
, vol.10
, pp. 405-455
-
-
Siebenlist, U.1
Franzoso, G.2
Brown, K.3
-
33
-
-
0029054725
-
RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death
-
Stanger, B. Z., P. Leder, T. H. Lee, E. Kim, and B. Seed. 1995. RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell 81:513-523.
-
(1995)
Cell
, vol.81
, pp. 513-523
-
-
Stanger, B.Z.1
Leder, P.2
Lee, T.H.3
Kim, E.4
Seed, B.5
-
34
-
-
0033119952
-
Embryonic lethality, liver degeneration, and impaired NF-κB activation in IKK-β-deficient mice
-
Tanaka, M., M. E., Fuentes, K., Yamaguchi, M. H., Durnin, S. A., Dalrymple, K. L., Hardy, and D. V. Goeddel. 1999. Embryonic lethality, liver degeneration, and impaired NF-κB activation in IKK-β-deficient mice. Immunity 10:421-429.
-
(1999)
Immunity
, vol.10
, pp. 421-429
-
-
Tanaka, M.1
Fuentes, M.E.2
Yamaguchi, K.3
Durnin, M.H.4
Dalrymple, S.A.5
Hardy, K.L.6
Goeddel, D.V.7
-
35
-
-
0029858348
-
RIP mediates tumor necrosis factor receptor 1 activation of NF-κB but not Fas/APO-1-initiated apoptosis
-
Ting, A. T., F. X., Pimentel-Muinos, and B. Seed. 1996. RIP mediates tumor necrosis factor receptor 1 activation of NF-κB but not Fas/APO-1-initiated apoptosis. EMBO J. 15:6189-6196.
-
(1996)
EMBO J.
, vol.15
, pp. 6189-6196
-
-
Ting, A.T.1
Pimentel-Muinos, F.X.2
Seed, B.3
-
36
-
-
0030611595
-
IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK
-
Woronicz, J. D., X., Gao, Z., Cao, M. Rothe, and D. V. Goeddel. 1997. IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK. Science 278:866-869.
-
(1997)
Science
, vol.278
, pp. 866-869
-
-
Woronicz, J.D.1
Gao, X.2
Cao, Z.3
Rothe, M.4
Goeddel, D.V.5
-
37
-
-
0032568792
-
Complementation cloning of NEMO, a component of the IκB kinase complex essential for NF-κB activation
-
Yamaoka, S., G., Courtois, C., Bessia, S. T., Whiteside, R, Weil, F., Agou, H. E., Kirk, R. J., Kay, and A. Israel. 1998. Complementation cloning of NEMO, a component of the IκB kinase complex essential for NF-κB activation. Cell 93:1231-1240.
-
(1998)
Cell
, vol.93
, pp. 1231-1240
-
-
Yamaoka, S.1
Courtois, G.2
Bessia, C.3
Whiteside, S.T.4
Weil, R.5
Agou, F.6
Kirk, H.E.7
Kay, R.J.8
Israel, A.9
-
38
-
-
0031463025
-
Early lethality, functional NF-κB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
-
Yeh, W. C., A., Shahinian, D., Speiser, J., Kraunus, F., Billia, A., Wakeham, J. L., de la Pompa, D., Ferrick, B., Hum, N., Iscove, P., Ohashi, M., Rothe, D. V., Goeddel, and T. W. Mak. 1997. Early lethality, functional NF-κB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice. Immunity 7:715-725.
-
(1997)
Immunity
, vol.7
, pp. 715-725
-
-
Yeh, W.C.1
Shahinian, A.2
Speiser, D.3
Kraunus, J.4
Billia, F.5
Wakeham, A.6
De La Pompa, J.L.7
Ferrick, D.8
Hum, B.9
Iscove, N.10
Ohashi, P.11
Rothe, M.12
Goeddel, D.V.13
Mak, T.W.14
-
39
-
-
0030613551
-
The IκB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IκB phosphorylation and NF-κB activation
-
Zandi, E., D. M. Rothwarf, M. Delhase, M. Hayakawa, and M. Karin. 1997. The IκB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IκB phosphorylation and NF-κB activation. Cell 91:243-252.
-
(1997)
Cell
, vol.91
, pp. 243-252
-
-
Zandi, E.1
Rothwarf, D.M.2
Delhase, M.3
Hayakawa, M.4
Karin, M.5
-
40
-
-
0032575379
-
Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: Discrimination between free and NF-kappaB-bound substrate
-
Zandi, E., Y., Chen, and M. Karin. 1998. Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate. Science 281:1360-1363.
-
(1998)
Science
, vol.281
, pp. 1360-1363
-
-
Zandi, E.1
Chen, Y.2
Karin, M.3
-
41
-
-
0033002197
-
Bridging the gap: Composition, regulation, and physiological function of the IκB kinase complex
-
Zandi, E., and M. Karin. 1999. Bridging the gap: composition, regulation, and physiological function of the IκB kinase complex. Mol. Cell. Biol. 19: 4547-4551.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 4547-4551
-
-
Zandi, E.1
Karin, M.2
-
42
-
-
0033712615
-
Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKγ) upon receptor stimulation
-
Zhang, S. Q., A., Kovalenko, G., Cantarella, and D. Wallach. 2000. Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKγ) upon receptor stimulation. Immunity 12:301-311.
-
(2000)
Immunity
, vol.12
, pp. 301-311
-
-
Zhang, S.Q.1
Kovalenko, A.2
Cantarella, G.3
Wallach, D.4
|