Distinct adapter proteins mediate acid versus neutral sphingomyelinase activation through the p55 receptor for tumor necrosis factor

Journal of Leukocyte Biology

Volumn 63, Issue 6, 1998, Pages 678-628

  Adam Klages, Sabine ^a   Schwandner, Ralf ^a   Adam, Dieter ^a   Kreder, Dirk ^a   Bernardo, Katussevani ^a   Krönke, Martin ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

Ceramide; FADD; RIP; TRADD; TRAF2

Indexed keywords

CERAMIDE; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR NECROSIS FACTOR;

APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DEATH; CELL PROLIFERATION; ENZYME ACTIVATION; NONHUMAN; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS REGULATION; SIGNAL TRANSDUCTION;

EID: 0031779350     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.63.6.678     Document Type: Article

References (49)

1. Tartaglia, L. A., Goeddel, D. V. (1992) Two TNF receptors. Immunol. Today 13, 151-153.
2. Aggarwal, B. B., Natarajan, K. (1996) Tumor necrosis factors: Developments during the last decade. Eur. Cytokine Network 7, 93-124.
3. Heller, R. A., Krönke, M. (1994) Tumor necrosis factor receptor-mediated signaling pathways. J. Cell Biol. 126, 5-9.
4. Krönke, M., Schütze, S., Wiegmann, K., Machleidt, T. (1996) Sphingomyelinases and TNF-induced apoptosis. Cell. Physiol. Biochem. 6, 1769-1771.
5. Verheij, M., Bose, R., Lin, X. H., Yao, B., Jarvis, W. D., Grant, S., Birrer, M. J., Szabo, E., Zon, L. I., Kyriakis, J. M., Haimovitz-Friedmann, A., Fuks, Z., Kolesnick, R. (1996) Requirement for ceramide-initiated SAPK/ JNK signalling in stress-induced apoptosis. Nature 380, 75-79.
6. Westwick, J. K., Bielawska, A. E., Dbaibo, G., Hannun, Y. A., Brenner, D. A. (1995) Ceramide activates the stress-activated protein kinases. J. Biol. Chem. 270, 22689-22692.
7. Muller, G., Ayoub, M., Storz, P., Rennecke, J., Fabbro, D., Pfizenmaier, K. (1995) PKCζ is a molecular switch in signal transduction of TNF-α, bifunctionally regulated by ceramide and arachidonic acid. EMBO J. 14, 1961-1969.
8. Machleidt, M., Krämer, B., Adam, D., Neumann, B., Schütze, S., Wiegmann, K., Krönke, M. (1996) Function of the p55 tumor necrosis factor receptor 'death domain' mediated by phosphatidylcholine-specific phospholipase C. J. Exp. Med. 184, 725-733.
9. Wiegmann, K., Schütze, S., Machleidt, T., Witte, D., Krönke, M. (1994) Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling. Cell 78, 1005-1015.
10. Yao, B., Zhang, Y. H., Delikat, S., Mathias, S., Basu, S., Kolesnick, R. (1995) Phosphorylation of Raf by ceramide-activated protein kinase. Nature 378, 307-310.
11. Zhang, Y., Yao, B., Delikat, S., Bayoumy, S., Lin, X.-H., Basu, S., McGinley, M., Chan-Hui, P-Y., Lichenstein, H., Kolesnick, R. (1997) Kinase suppressor of Ras is ceramide-activated protein kinase. Cell 89, 63-72.
12. Victor, I., Schwenger, P., Li, W., Schlessinger, J., Vilcek, J. (1993) Tumor necrosis factor-induced activation and increased tyrosine phosphorylation of mitogen-activated protein (MAP) kinase in human fibroblasts. J. Biol. Chem. 268, 18994-18999.
13. 2 is phosphorylated and activated by MAP kinase. Cell 72, 269-278.
14. Tartaglia, L. A., Ayres, T. M., Wong, G. H. W., Goeddel, D. V. (1993) A novel domain within the 55 kd TNF receptor signals cell death. Cell 74, 845-853.
15. Adam, D., Wiegmann, K., Adam-Klages, S., Ruff, A., Krönke, M. (1996) A novel cytoplasmic domain of the p55 TNF receptor initiates the neutral sphingomyelinase pathway. J. Biol. Chem. 271, 14617-14622.
16. Bazzoni, F., Beutler, B. (1995) How do tumor necrosis factor receptors work? J. Inflammation 45, 221-238.
17. Hsu, H., Xiong, J., Goeddel, D. V. (1995) The TNF receptor 1-associated protein TRADD signals cell death and NF-KB activation. Cell 81, 495-504.
18. Hsu, H., Shu, H.-B., Pan, M.-G., Goeddel, D. V. (1996) TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 84, 299-308.
19. Hsu, H., Huang, J., Shu, H.-B., Baichwal, V., Goeddel, D. V. (1996) TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 4, 387-396.
20. Malinin, N. L., Boldin, M. P., Kovalenko, A. V., Wallach, D. (1997) MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1. Nature 385, 540-544.
21. Régnier, C. H., Song, H. Y., Gao, X., Goeddel, D. V., Cao, Z., Rothe, M. (1997) Identification and characterization of an IκB kinase. Cell 90, 373-383.
22. DiDonato, J. A., Hayakawa, M., Rothwarf, D. M., Zandi, E., Karin, M. (1997) A cytokine-responsive IκB kinase that activates the transcription factor NFκB. Nature 388, 548-554.
23. Maniatis, T. (1997) Catalysis by a multiprotein IκB kinase complex. Science 278, 818-819.
24. Muzio, M., Chinnaiyan, A. M., Kischkel, F. C., O'Rourke, K., Shevchenko, A., Ni, J., Scaffidi, C., Bretz, J. D., Zhang, M., Gentz, R., Mann, M., Krammer, P. H., Peter, M. E., Dixit, V. M. (1996) FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing complex. Cell 85, 817-827.
25. Boldin, M. P., Goncharov, T. M., Goltsev, Y. V., Wallach, D. (1996) Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1 and TNF receptor-induced cell death. Cell 85, 803-815.
26. Nicholson, D. W., Thornberry, N. A. (1997) Caspases: killer proteases. Trends Biochem. Sci. 22, 299-306.
27. Wallach, D. (1997) Cell death induction by TNF: a matter of self control. Trends Biochem. Sci. 22, 107-109.
28. Song, H. Y., Dunbar, J. D., Zhang, Y. X., Guo, D., Donner, D. B. (1995) Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor. J. Biol. Chem. 270, 3574-3581.
29. Boldin, M. P., Mett, I. L., Wallach, D. (1995) A protein related to a proteasomal subunit binds to the intracellular domain of the p55 TNF receptor upstream to its 'death domain.' FEBS Lett. 367, 39-44.
30. Castellino, A. M., Parker, G. J., Boronenkov, I. V., Anderson, R. A., Chao, M. V. (1997) A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase. J. Biol. Chem. 272, 5861-5870.
31. 30a. Schwandner, R., Wiegmann, K., Bernardo, K., Kreder, D., Krönke, M. (1998). TNF receptor death domain-associated proteins TRADD and FADD signal activation of acid sphingomyelinase. J. Biol. Chem. 273, 5916-5922.
32. Cifone, M. G., Roncaioli, P., De Maria, R., Camarda, G., Santoni, A., Ruberti, G., Testi, R. (1995) Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal. EMBO J. 14, 5859-5868.
33. Brenner, B., Ferlinz, K., Grassmé, H., Weller, M., Koppenhoefer, U., Dichgans, J., Sandhoff, K., Lang, F., Gulbins, E. (1998) Fas/CD95/Apo-1 activates the acidic sphingomyelinases via caspases. Cell Death Diff. 5, 29-33.
34. Gyuris, J., Golemis, E., Chertkov, H., Brent, R. (1993) Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell 75, 791-803.
35. Adam, D., Adam-Klages, S., Krönke, M. (1996) Identification of p55 tumor necrosis factor receptor-associated proteins that couple to signaling pathways not initiated by the death-domain. J. Inflammation 47, 61-66.
36. Adam-Klages, S., Adam, D., Wiegmann, K., Struve, S., Kolanus, W., Schneider-Mergener, J., Krönke, M. (1996) FAN, a novel WD-repeat protein couples the p55 TNF-receptor to neutral sphingomyelinase. Cell 86, 937-947.
37. Neer, E. J., Schmidt, C. J., Nambudripad, R., Smith, T. F. (1994) The ancient regulatory-protein family of WD-repeat proteins. Nature 371, 297-300.
38. Watson, A. J., Katz, A., Simon, M. I. (1994) A fifth member of the mammalian G-protein β-subunit family. J. Biol. Chem. 269, 22150-22156.
39. 2-activating protein. Proc. Natl. Acad. Sci. USA 88, 5418-5422.
40. Mayer, R. E., Hendrix, P., Cron, P., Matthies, R., Stone, S. R., Goris, J., Merlevede, W., Hofsteenge, J., Hemmings, B. A. (1991) Structure of the 55 kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal specific isoform. Biochemistry 30, 3589-3597.
41. Chen, R.-H., Miettinen, P. J., Maruoka, E. M., Choy, L., Derynck, R. (1995)A WD-domain protein that is associated with and phosphorylated by the type II TGF-b receptor. Nature 377, 548-552.
42. Zou, H., Henzel, W. J., Liu, X., Lutschg, A., Wang, X. (1997) Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90, 405-413.
43. Nagle, D. L., Karim, M. A., Woolf, E. A., Holmgren, L., Bork, P., Misumi, D. J., McGrail, S. H., Dussault, B. J., Jr., Perou, C. M., Boissy, R. E., Duyk, G. M., Spritz, R. A., Moore, K. J. (1996) Identification and mutation analysis of the complete gene for Chediak-Higashi syndrome. Nature Genet. 14, 307-311.
44. Perou, C. M., Moore, K. J., Nagle, D. L., Misumi, D. J., Woolf, E. A., McGrail, S. H., Holmgren, L., Brody, T. H., Dussault, B. J., Jr., Monroe, C. A., Duyk, G. M., Pryor, R. J., Li, L., Justice, M. J., Kaplan, J. (1996) Identification of the murine beige gene by YAK complementation and positional cloning. Nature Genet. 13, 303-308.
45. Spicer, S. S., Sato, A., Vincent, R., Eguchi, M., Poon, K. C. (1981) Lysosome enlargement in the Chediak-Higashi syndrome. Federation Proc. 40, 1451-1455.
46. Sabatini, D. M., Erdjument-Bromage, H., Lui, M., Tempst, P., Snyder, S. H. (1994) RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs. Cell 78, 35-43.
47. Zheng, X. F., Florentino, D., Chen, J., Crabtree, G. R., Schreiber, S. L. (1995) TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin. Cell 82, 121-130.
48. DiFiglia, M., Sapp, E., Chase, K., Schwarz, C., Meloni, A., Young, C., Martin, E., Vonsattel, J. P., Carraway, R., Reeves, S. A., et al. (1995) Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons. Neuron 14, 1075-1081.
49. Feuchter, A. E., Freeman, J. D., Mager, D. L. (1992) Strategy for detecting cellular transcripts promoted by human endogenous long terminal repeats: identification of a novel gene (CDC4L) with homology to yeast CDC4. Genomics 13, 1237-1246.