MAP kinase activation in macrophages

Journal of Leukocyte Biology

Volumn 69, Issue 1, 2001, Pages 3-10

  Rao, K Murali Krishna ^a,b  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

CD14; GCK; TNF; Toll; TRAF

Indexed keywords

CD14 ANTIGEN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; HUMANS; MACROPHAGE ACTIVATION; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0035154914     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (117)

1. MAP kinase pathways
2. Growth factors and mitogen-activated protein kinases
3. MAPKs: New JNK expands the group
4. Sounding the alarm: Protein kinase cascades activated by stress and inflammation
5. A phosphatidylcholine-specific phospholipase C regulates activation of p42/p44 mitogen-activated protein kinases in lipopolysaccharide-stimulated human alveolar macrophages
6. Both Erk and p38 kinases are necessary for cytokine gene transcription
7. MAPK-dependent expression of p21(WAF) and p27(kip1) in PMA-induced differentiation of HL60 cells
8. Signal transduction pathways in normal human monocytes stimulated by cytokines and mediators: Comparative study with normal human neutrophils or transformed cells and the putative roles in functionality and cell biology
9. CD-14-dependent activation of protein kinase C and mitogen activated protein kinases (p42 and p44) in human monocytes treated with bacterial lipopolysaccharide
10. Pro-inflammatory cytokines and environmental stress cause p38 mitogen protein kinase activation by dual phosphorylation on tyrosine and threonine
11. 2 production in lipopolysaccharide-stimulated monocytes
12. MAP-kinase dependent induction of monocytic procoagulant activity by β2-intgrins
13. Involvement of small GTPases in Mycoplasma fermentas membrane lipoprotein-mediated activation of macrophages
14. Activation of C-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages
15. ERK signaling mediates the induction of inflammatory cytokines by bufalin in human monocytic cells
16. Oxidized LDL-containing immune complexes induce Fcγ-receptor 1-mediated mitogen-activated protein kinase activation in THP-1 macrophages
17. Activation of mitogen-activated protein kinase pathway in U937 leukemie cells induces phosphorylation of the amino terminus of the TATA-binding protein
18. + macrophages
19. Differences in the kinetics of activation of protein kinases and extracelluar signal-related protein kinase 1 in colony-stimulating factor 1-stimulated and lipopolysaccharide- stimulated macrophages
20. Involvement of Ras and MAP kinase (ERK-1) in cisplatin-induced activation of murine bone marrow-derived macrophages
21. Potential role of the JNK/SAPK signal transduction pathway in the induction of iNOS by TNF-α
22. The differential time-course of extracellular-regulated kinase activity correlates with the macrophage response toward proliferation or activation
23. Protein phosphatase 2A is expressed in response to colony-stimulating factor 1 in macrophages and is required for cell cycle progression independently of extracellular signal-regulated protein kinase activity
24. Roles of the mitogen-activated protein kinase family in macrophage responses to colony-stimulating factor-1 addition and withdrawal
25. Evalualion of the role of mitogen-activated protein kinases in the expression of inducible nitric oxide synthase by IFN-γ and TNF-α in mouse macrophages
26. mapk, MKK3, and MKK4 by TNF-α in mouse bone-marrow-derived macrophages
27. Activation of p42 mapk/erk2 following engagement of TNF receptor CD120a (p55) in mouse macrophages
28. Involvement of MAP-kinases and -phosphatases in uptake and intracellular replication of Listeria monocytogenes in J774 macrophage cells
29. 2-terminal kinase. Correlation with is inhibitory effect on tumor necrosis factor-α production
30. Murine hepatitis virus strain 3 induces the macrophage prothrombinase fgl-2 through p38 mitogen-activated protein kinase activation
31. The annexin protein lipocortin 1 regulates the MAPK/ERK pathway
32. Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in macrophages
33. Mitogen-activated protein kinase pathway mediates hyperoxia-induced apoptosis in cultured macrophage cell lines
34. Activation of multiple proline-directed kinases by bacterial lipopolysaccharide in murine macrophages
35. Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-α) translation: Glucocorticoids inhibit TNF-α translation by blocking JNK/SAPK
36. p38 but not p44/42 mitogen-activated protein kinase is required for nitric oxide synthase induction mediated by lipopolysaccharide in RAW 264.7 macrophages
37. Specific inhibitors of p38 and extracellular-regulated kinase mitogen activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine macrophages stimulated with lipopolysaccharide and interferon-γ
38. Sodium salicylate inhibits macrophage TNF-α production and alters MAPK activation
39. Mature macrophage cell lines exhibit variable responses to LPS
40. Effects of Wortmannin and rapamycin on CSF-1-mediated responses in macrophages
41. Interaction of calcium/calmodulin-dependent protein kinases (CaMK) and extracellular-regulated kinase (ERK) in monocyte adherence and TNF-α production
42. Terminal differentiation of murine resident macrophages is characterized by expression of the STK protein tyrosine kinase, a receptor macrophage stimulating protein
43. Action and target cell specificity of human macrophage stimulating protein (MSP)
44. Activation of RON receptor tyrosine kinase inhibits inducible nitric oxide synthase (iNOS) expression by murine peritoneal exudate macrophages: Phosphatidylinositol-3 kinase is required for RON-mediated inhibition of iNOS expression
45. Macrophage and monocyte IL-1 beta regulation differs at multiple sites. Messenger RNA expression, translation, and post-translational processing
46. Analysis of the IFN-γ-signaling pathway in macrophages at different stages of maturation
47. Human alveolar macrophages are markedly deficient in REF-1 and AP-1 DNA binding activity
48. Asbestos stimulation triggers differential cytokine release from human monocytes and alveolar macrophages
49. Changes in PKC isoforms in human alveolar macrophages compared with blood monocytes
50. Activation of TNF-α transcription utilizes distinct MAP kinase pathways in different macrophage populations
51. Regulation of monocyte IL-10 synthesis by endogenous IL-1 and TNF-α: Role of the p38 and p42/44 mitogen-activated protein kinases
52. p38 and extracellular signal-regulated kinase mitogen-activated protein kinase activities are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor
53. Endotoxin signal transduction in macrophages
54. Structure and function of lipopolysaccharide binding protein
55. Toll, a new piece in the puzzle of innate immunity
56. Toll receptors: An expanding role in our understanding of human disease
57. Host defence mechanisms triggered by microbial lipoproteins through toll-like receptors
58. The human toll signaling pathway: Divergence of nuclear factor κB and JNK/SAPK activation upstream of minor necrosis factor receptor-associated factor 6 (TRAF6)
59. Cutting edge: Cell surface receptor expression and lipopolysaccharide signaling via toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages
60. Defective LPS signaling in C3H/HeJ mice and C57BL10SeCr mice: Mutations in Tlr4 gene
61. Endotoxin-tolerant mice have mutations in toll-like receptor 4 (Tlr4)
62. Toll-like receptor 4 (TLR-4)-deficient mice are hyperresponsive to lipopolysaccharide: Evidence for TLr4 as the lps gene product
63. Cellular events mediated by lipopolysaccharide-stimulated toll-like receptor 4. MD-2 is required for activation of mitogen-activated protein kinases and Elk-1
64. Involvement of protein kinase C and protein tyrosine kinase in lipopolysaccharide-induced TNF-α and IL-1β production by human monocytes
65. Phosphatidylinositol 3-kinase-dependent activation of protein kinase C-zeta in bacterial lipopolysaccharde-treated human monocytes
66. Protein kinase Cδ activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf
67. Defective lipopolysaccharide-dependent ERK1/2 activation in endotoxin tolerant murine macrophages is reversed by direct protein kinase C stimulation
68. Lipopolysaccharide signals activation of tumor necrosis factor biosynthesis through the Ras/Raf-1/MEK/MAP pathway
69. Lipopolysaccharide induces activation of Raf-1/MAP kinase pathway
70. Monocyte deactivation by interleukin 10 via inhibition of tyrosine kinase activity and the ras signaling pathway
71. Phosphorylation of Raf by ceramide-activated protein kinase
72. Two TNF receptors
73. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
74. TRAF2-mediated activation of NFκB by TNF receptor 2 and CD40
75. Dissection of TNF receptor 1 effector functions: JNK activation is not related to apoptosis while NFκB activation prevents cell death
76. Activation of SAPK/JUNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway
77. ASK1 is essential for JNK/SAPK activation by TRAF2
78. MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase
79. Differential expression of a novel protein kinase C in human B lymphocytes. Preferential localization to the germinal center
80. Activation of the SAPK pathway by the human STE homologue germinal center kinase
81. Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade
82. HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway
83. Activation of stress-activated protein kinase/c-Jun N-terminal kinase, but not NF-κB, by tumor necrosis factor (TNF) receptor 1 through a TNF receptor-associated factor 2- and germinal center kinase related-dependent pathway
84. Signaling by the germinal center kinase family of protein kinases
85. Macrophage colony-stimulating factor induces the expression of mitogen-activated protein kinase phosphatase-1 through a protein kinase C-dependent pathway
86. Proliferation-independent induction of macrophage cyclin D2, and repression of cyclin D1, by lipopolysaccharide
87. Phorbol ester-resistant munoblastoid leukemia cells with a functional mitogen-activated protein kinase cascade but without responsive protein tyrosine phosphatases
88. Prolonged activation of the mitogen-activated protein kinase pathway is required for macrophage-like differentiation of a human myeloid leukemic cell line
89. A dual function for p38 MAP kinase in hematopoietic cells: Involvement in apoptosis and cell activation
90. Differential expression and activation of p38 mitogen-activated protein kinase α, β, γ, and δ in inflammatory cell lineage
91. Coordinate activation of endogenous p38α, β, γ, and δ by inflammatory stimuh
92. Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells
93. Regulation and function of protein kinase B and MAP kinase activation by the IL-5/GM-CSF/IL-3 receptor
94. Deficiency of the stress kinase p38 results in embryonic lethality: Characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells
95. The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain
96. Activation of ternary complex factor Elk-1 by MAP kinases
97. ATF-2 contains a phosphorylation-dependent transcriptional activation domain
98. JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the e-Jun activation domain
99. Mechanism of action of bicyclic imidazoles defines a translational regulatory pathway for tumor necrosis factor alpha
100. Human eukaryotic translation initiation factor 4G (elF4G) recruits Mnk1 to phosphorylate elF4E
101. The phosphorylation of eukaryotic initiation factor elF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways
102. Mechanisms of suppression macrophage nitric oxide release by transforming growth factor-β
103. Peripheral blood mononuclear cells stimulated with C5a or lipopolysaccharide to synthesize equivalent levels of IL-1β mRNA show unqeual IL-1β protein accumulation but similar polyribosome profile
104. Raf-1 is activated by the p38 mitogen-activated protein kinase inhibitor. SB 203580
105. Direct inhibition of cyclooxygenase-1 and -2 by the kinase inhibitors SB 203530 and PD 98059. SB 203580 also inhibits thromboxane synthase
106. Stress-signaling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3
107. SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis
108. Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity
109. Requirement of mitogen-activated protein kinase kinase (MKK3) for tumor necrosis factor-induced cytokine expression
110. Defective thymocyte maturation in p44 MAP kinase (ERK 1) knockout mice
111. Constitutively active MAP kinase kinase (MEK1) stimulates SAP kinase and c-Jun transcriptional activity in U937 human leu kemic cells
112. A strategy to make constitutively active MAP kinase by fusing with constitutively active MAP kinase kinase
113. Constitutive activation of MAPK pathway mediates v-fes-inudeed mitogenesis in murine macrophages
114. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation
115. Interferon-γ expression by TH1 effector cells mediated by the p38 MAP kinase signaling pathway
116. Transforming growth factor β1 inhibits mitogen-activated protein kinase induced by basic fibroblast growth factor in smooth muscle cells
117. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis