Curcumin sensitizes lung cancer cells to cisplatin-induced apoptosis through superoxide anion-mediated Bcl-2 degradation

Cancer Investigation

Volumn 27, Issue 6, 2009, Pages 624-635

  Chanvorachote, Pithi ^a   Pongrakhananon, Varisa ^a   Wannachaiyasit, Sumalee ^b   Luanpitpong, Sudjit ^a   Rojanasakul, Yon ^c   Nimmannit, Ubonthip ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b SILPAKORN UNIVERSITY   (Thailand)

^c WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

Apoptosis; Bcl 2 degradation; Cisplatin; Curcumin; Lung cancer

Indexed keywords

CISPLATIN; CURCUMIN; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; ANTINEOPLASTIC AGENT; PROTEASOME;

APOPTOSIS; ARTICLE; CANCER CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG POTENTIATION; DRUG SENSITIZATION; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; PRIORITY JOURNAL; PROTEIN DEGRADATION; DOSE RESPONSE; DRUG EFFECT; DRUG RESISTANCE; GENETIC TRANSFECTION; GENETICS; LUNG TUMOR; METABOLISM; PATHOLOGY; PROTEIN PROCESSING; TIME; TUMOR CELL LINE;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CISPLATIN; CURCUMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG RESISTANCE, NEOPLASM; HUMANS; LUNG NEOPLASMS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-BCL-2; SUPEROXIDES; TIME FACTORS; TRANSFECTION;

EID: 67649976963     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.1080/07357900802653472     Document Type: Article

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