Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 14, 2009, Pages 5219-5228

  Bora Tatar, Gamze ^a   Dayangaç Erden, Didem ^a   Demir, Ayhan S ^b   Dalkara, Sevim ^a   Yelekçi, Kemal ^c   Erdem Yurter, Hayat ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

^b MIDDLE EAST TECHNICAL UNIVERSITY   (Turkey)

^c KADIR HAS UNIVERSITY   (Turkey)

Author keywords

Caffeic acid derivatives; Carboxylic acid derivatives; Chlorogenic acid; Curcumin; HDAC inhibitors; Molecular docking

Indexed keywords

ARYLBUTYRIC ACID DERIVATIVE; BUTYRIC ACID; CAFFEIC ACID DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; CHLOROGENIC ACID; CINNAMIC ACID; CURCUMIN; HISTONE DEACETYLASE 8; HISTONE DEACETYLASE INHIBITOR; VALPROIC ACID;

ARTICLE; CHEMICAL MODIFICATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG SCREENING; ENZYME INHIBITION; FLUOROMETRY; HELA CELL; HUMAN; HUMAN CELL; MOLECULAR DOCKING; STRUCTURE ACTIVITY RELATION;

CAFFEIC ACIDS; CARBOXYLIC ACIDS; CATALYTIC DOMAIN; CHLOROGENIC ACID; CURCUMIN; ENZYME INHIBITORS; HELA CELLS; HISTONE DEACETYLASES; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN BINDING;

EID: 67650078931     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.05.042     Document Type: Article

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