Curcumin inhibits phorbol ester-induced up-regulation of cyclooxygenase-2 and matrix metalloproteinase-9 by blocking ERK1/2 phosphorylation and NF-κB transcriptional activity in MCF10A human breast epithelial cells

Antioxidants and Redox Signaling

Volumn 7, Issue 11-12, 2005, Pages 1612-1620

  Lee, Ki Won ^a   Kim, Jung Hwan ^a   Lee, Hyong Joo ^a   Surh, Young Joon ^a  

^a Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; AMPHOTERICIN B DEOXYCHOLATE; CURCUMIN; CYCLOOXYGENASE 2; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PENICILLIN G; PHORBOL 13 ACETATE 12 MYRISTATE; PROSTAGLANDIN E2; STREPTOMYCIN; TUMOR PROMOTER;

ARTICLE; BREAST EPITHELIUM; CANCER CELL; CELL INVASION; CELL MOTILITY; CELL TRANSFORMATION; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; TRANSACTIVATION;

BREAST; CATALYSIS; CELL LINE; CURCUMIN; CYCLOOXYGENASE 2; DINOPROSTONE; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MOLECULAR STRUCTURE; NF-KAPPA B; PHORBOL ESTERS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RNA, MESSENGER; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 28844479049     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2005.7.1612     Document Type: Article

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