The inhibitory mechanism of curcumin and its derivative against β-catenin/Tcf signaling

FEBS Letters

Volumn 579, Issue 13, 2005, Pages 2965-2971

  Chi, Hoon Park ^a   Eun, Ryeong Hahm ^a   Park, Seyeon ^b   Kim, Hyun Kyung ^a   Chul, Hak Yang ^a  

^a Seoul National University   (South Korea)

^b Yonsei University   (South Korea)

Author keywords

Catenin Tcf signaling; Curcumin; Nuclear catenin; T cell factor 4

Indexed keywords

APC PROTEIN; AXIN; BETA CATENIN; CHC 007; CURCUMIN; GENE PRODUCT; GLYCOGEN SYNTHASE KINASE 3BETA; MEMBRANE PROTEIN; MUTANT PROTEIN; NUCLEAR PROTEIN; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOSOL; DNA BINDING; DOWN REGULATION; DRUG DETERMINATION; DRUG MECHANISM; ENZYME ASSAY; ENZYME DEGRADATION; GEL MOBILITY SHIFT ASSAY; GENE ACTIVITY; GENE INDUCTION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REPORTER GENE; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

BASE SEQUENCE; BETA CATENIN; CELL LINE; CURCUMIN; CYTOSKELETAL PROTEINS; DNA PRIMERS; HUMANS; PROTEIN BINDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TCF TRANSCRIPTION FACTORS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 19444362674     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.04.013     Document Type: Article

References (31)

1. M. Mareel, T. Boterberg, V. Noe, L. van Hoorde, S. Vermuelen, E. Bruyneel, and M. Bracke E-cadherin/catenin/cytoskeleton complex: a regulator of cancer invasion J. Cell. Physiol. 173 1997 271 274
2. L.C. Bullions, and A.J. Levine The role of β-catenin in cell adhesion, signal transduction and cancer Curr. Opin. Oncol. 10 1998 81 87
3. T.C. He, A.B. Sparks, C. Rago, H. Hermeking, L. Zawel, L.T. da Costa, P.J. Morin, B. Vogelstein, and K.W. Kinzler Identification of c-MYC as a target of the APC pathway Science 281 1998 1509 1512
4. O. Tetsu, and F. McCormick β-catenin regulates expression of cyclin D1 in colon carcinoma cells Nature 398 1999 422 426
5. B. Mann, M. Gelos, A. Siedow, M.L. Hanski, A. Gratchev, M. Ilyas, W.F. Bodmer, M.P. Moyer, E.O. Riecken, H.J. Buhr, and C. Hanski Target genes of β-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas Proc. Natl. Acad. Sci. USA 96 1999 1603 1608
6. B. Rubinfeld, I. Albert, E. Porfiri, C. Fiol, S. Munemitsu, and P. Polakis Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly Science 272 1996 1023 1026
7. P.J. Morin, A.B. Sparks, and V. Korinek Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC Science 275 1997 1787 1790
8. H. Fujie, K. Moriya, Y. Shintani, T. Tsutsumi, T. Takayama, M. Makuuchi, S. Kimura, and K. Koike Frequent β-catenin aberration in human hepatocellular carcinoma Hepatol. Res. 20 2001 39 51
9. D.K. Woo, H.S. Kim, H.S. Lee, Y.H. Kang, H.K. Yang, and W.H. Kim Altered expression and mutation of β-catenin gene in gastric carcinomas and cell lines Int. J. Cancer 95 2001 108 113
10. S. Dihlmann, A. Siermann, and M.K. Doeberitz The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate β-catenin/Tcf-4 signaling Oncogene 20 2001 645 653
11. R.R. Satoskar, S.J. Shah, and S.G. Shenoy Evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation Int. J. Clin. Pharmacol. Ther. Toxicol. 24 1986 651 654
12. H. Ohtsu, Z. Xiao, J. Ishida, M. Nagai, H.K. Wang, H. Itokawa, C.Y. Su, C. Shih, T. Chiang, E. Chang, Y. Lee, M.Y. Tsai, C. Chang, and K.H. Lee Antitumor agents. 217. Curcumin analogues as novel androgen receptor antagonists with potential as anti-prostate cancer agents J. Med. Chem. 45 2002 5037 5042
13. J.S. Shim, D.H. Kim, H.J. Jung, J.H. Kim, D. Lim, S.K. Lee, K.W. Kim, J.W. Ahn, J.S. Yoo, J.R. Rho, J. Shin, and H.J. Kwon Hydrazinocurcumin, a novel synthetic curcumin derivative, is a potent inhibitor of endothelial cell proliferation Bioorg. Med. Chem 10 2002 2987 2992
14. E.R. Hahm, Y.S. Gho, S. Park, C.H. Park, K.W. Kim, and C.H. Yang Synthetic curcumin analogs inhibit activator protein-1 transcription and tumor-induced angiogenesis Biochem. Biophys. Res. Commun. 321 2004 337 344
15. E.R. Hahm, G. Cheon, J. Lee, B. Kim, C.H. Park, and C.H. Yang New and known symmetrical curcumin derivatives inhibit the formation of Fos-Jun-DNA complex Cancer Lett. 184 2002 89 96
16. A.S. Jaiswal, B.P. Marlow, N. Gupta, and S. Narayan β-Catenin- mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells Oncogene 21 2002 8414 8427
17. N.N. Mahmoud, A.M. Carothers, D. Grunberger, R.T. Bilinski, M.R. Churchill, C. Martucci, H.L. Newmark, and M.M. Bertagnolli Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis Carcinogenesis 21 2000 921 927
18. M. Bordonaro, J.M. Mariadason, F. Aslam, B.G. Heerdt, and L.H. Augenlicht Butyrate-induced apoptotic cascade in colonic carcinoma cells: modulation of the β-catenin-Tcf pathway and concordance with effects of sulindac and trichostatin A but not curcumin Cell Growth Differ. 10 1999 713 720
19. K.W. Kinzler, and B. Vogelstein Lessons from hereditary colorectal cancer Cell 87 1996 159 170
20. K. Caca, F.T. Kolligs, X. Ji, M. Hayes, J. Qian, A. Yahanda, D.L. Rimm, J. Costa, and E.R. Fearon β- and γ-Catenin mutations, but not E-cadherin inactivation, underlie T-cell factor/lymphoid enhancer factor transcriptional deregulation in gastric and pancreatic cancer Cell Growth Differ. 10 1999 369 376
21. S.H. Gardner, G. Hawcroft, and M.A. Hull Effect of nonsteroidal anti-inflammatory drugs on β-catenin protein levels and catenin-related transcription in human colorectal cancer cells Br. J. Cancer 91 2004 153 163
22. S.C. Hsu, J. Galceran, and R. Grosschedl Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with β-catenin Mol. Cell. Biol. 18 1998 4807 4818
23. K. Vleminckx, R. Kemler, and A. Hecht The C-terminal transactivation domain of β-catenin is necessary and sufficient for signaling by the LEF-1/β-catenin complex in Xenopus laevis Mech. Dev. 81 1999 49 58
24. P. Polakis Wnt signaling and cancer Genes Dev. 14 2000 1837 1851
25. J. Zhurinsky, M. Shtutman, and A. Ben-Ze'ev Plakoglobin and β-catenin: protein interactions, regulation and biological roles J. Cell Sci. 113 2000 3127 3139
26. S. Dihlmann, S. Klein, and M. von Knebel Doeberitz Reduction of β-catenin/T-cell transcription factor signaling by aspirin and indomethacin is caused by an increased stabilization of phosphorylated β-catenin Mol. Cancer Ther. 2 2003 509 516
27. N. Nath, K. Kashfi, J. Chen, and B. Rigas Nitric oxide-donating aspirin inhibits β-catenin /T cell factor (TCF) signaling in SW480 colon cancer cells by disrupting the nuclear β-catenin-TCF association Proc. Natl. Acad. Sci. USA 100 2003 12584 12589
28. 2 at physiologically relevant EGCG concentrations Biochem. Biophys. Res. Commun. 296 2002 584 588
29. B.R. Henderson Nuclear-cytoplasmic shuttling of APC regulates β-catenin subcellular localization and turn over Nat. Cell. Biol. 2 2000 653 660
30. A. Eleftheriou, M. Yoshida, and B.R. Henderson Nuclear export of human β-catenin can occur independent of CRM1 and the adenomatous polyposis coli tumor suppressor J. Biol. Chem. 276 2001 25883 25888
31. B.R. Henderson, M. Galea, S. Schuechner, and L. Leung Lymphoid enhancer factor-1 blocks adenomatous polyposis coli-mediated nuclear export and degradation of β-catenin J. Biol. Chem. 277 2002 24258 24264