The Aurora-A/TPX2 complex: A novel oncogenic holoenzyme?

Biochimica et Biophysica Acta - Reviews on Cancer

Volumn 1806, Issue 2, 2010, Pages 230-239

  Asteriti, Italia Anna ^a   Rensen, Wilhelmina Maria ^a   Lindon, Catherine ^b   Lavia, Patrizia ^a   Guarguaglini, Giulia ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Aurora A; Cancer; TPX2

Indexed keywords

AURORA A KINASE; BINDING PROTEIN; TARGETING PROTEIN FOR XKLP2; UNCLASSIFIED DRUG; PROTEIN TPX2; REGULATOR PROTEIN;

AURORA A ONCOGENE; CARCINOGENESIS; CARCINOGENICITY; CELL TRANSFORMATION; COMPLEX FORMATION; DATA MINING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; GENE; GENE OVEREXPRESSION; HUMAN; MITOCHONDRION; MOLECULARLY TARGETED THERAPY; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; REVIEW; TPX2 ONCOGENE; UPREGULATION; AURORA A GENE; CANCER THERAPY; CELL PROLIFERATION; GENE AMPLIFICATION; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOMIC INSTABILITY; MITOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; TPX2 GENE; TUMOR CLASSIFICATION;

ANIMALS; CELL CYCLE PROTEINS; HOLOENZYMES; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MITOSIS; NEOPLASMS; NUCLEAR PROTEINS; ONCOGENES; PROTEIN-SERINE-THREONINE KINASES;

EID: 78649511384     PISSN: 0304419X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbcan.2010.08.001     Document Type: Review

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