Dissecting the role of Aurora A during spindle assembly (EMBO Journal (2008) 27, (2567-2579) DOI:10.1038/emboj.2008.173);Dissecting the role of Aurora A during spindle assembly

EMBO Journal

Volumn 27, Issue 19, 2008, Pages 2567-2579

  Sardon, Teresa ^a   Peset, Isabel ^a   Petrova, Boryana ^a,b   Vernos, Isabelle ^a  

^a CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Aurora A; Centrosome; Microtubule; RanGTP; Spindle assembly

Indexed keywords

AURORA A KINASE; RAN PROTEIN;

ARTICLE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CENTROMERE; CONTROLLED STUDY; CYTOPLASM; EGG; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; MICROTUBULE ASSEMBLY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; XENOPUS;

EID: 53549133349     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2008.224     Document Type: Erratum

References (24)

1. Albee AJ, Tao W, Wiese C (2006) Phosphorylation of maskin by Aurora-A is regulated by RanGTP and importin beta. J Biol Chem 281: 38293-38301
2. Barr AR, Gergely F (2007) Aurora-A: the maker and breaker of spindle poles. J Cell Sci 120: 2987-2996
3. Bayliss R, Sardon T, Ebert J, Lindner D, Vernos I, Conti E (2004) Determinants for Aurora-A activation and Aurora-B discrimination by TPX2. Cell Cycle 3: 404-407
4. Bayliss R, Sardon T, Vernos I, Conti E (2003) Structural basis of Aurora-A activation by TPX2 at the mitotic spindle. Mol Cell 12: 851-862
5. Brunet S, Sardon T, Zimmerman T, Wittmann T, Pepperkok R, Karsenti E, Vernos I (2004) Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts. Mol Biol Cell 15: 5318-5328
6. Carazo-Salas RE, Gruss OJ, Mattaj IW, Karsenti E (2001) Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly. Nat Cell Biol 3: 228-234
7. De Luca M, Lavia P, Guarguaglini G (2006) A functional interplay between Aurora-A, Plk1 and TPX2 at spindle poles: Plk1 controls centrosomal localization of Aurora-A and TPX2 spindle association. Cell Cycle 5: 296-303
8. Desai A, Murray A, Mitchison TJ, Walczak CE (1999) The use of Xenopus egg extracts to study mitotic spindle assembly and function in vitro. Methods Cell Biol 61: 385-412
9. Gadea BB, Ruderman JV (2006) Aurora B is required for mitotic chromatin-induced phosphorylation of Op18/Stathmin. Proc Natl Acad Sci USA 103: 4493-4498
10. Gergely F (2002) Centrosomal TACCtics. Bioessays 24: 915-925
11. Girdler F, Gascoigne KE, Eyers PA, Hartmuth S, Crafter C, Foote KM, Keen NJ, Taylor SS (2006) Validating Aurora B as an anti-cancer drug target. J Cell Sci 119: 3664-3675
12. Groen AC, Cameron LA, Coughlin M, Miyamoto DT, Mitchison TJ, Ohi R (2004) XRHAMM functions in ran-dependent microtubule nucleation and pole formation during anastral spindle assembly. Curr Biol 14: 1801-1811
13. Gruss OJ, Vernos I (2004) The mechanism of spindle assembly: functions of Ran and its target TPX2. J Cell Biol 166: 949-955
14. Haydon CE, Eyers PA, Aveline-Wolf LD, Resing KA, Maller JL, Ahn NG (2003) Identification of novel phosphorylation sites on Xenopus laevis Aurora A and analysis of phosphopeptide enrichment by immobilized metal-affinity chromatography. Mol Cell Proteomics 2: 1055-1067
15. Hoar K, Chakravarty A, Rabino C, Wysong D, Bowman D, Roy N, Ecsedy JA (2007) MLN8054, a small-molecule inhibitor of Aurora A, causes spindle pole and chromosome congression defects leading to aneuploidy. Mol Cell Biol 27: 4513-4525
16. Kelly AE, Sampath SC, Maniar TA, Woo EM, Chait BT, Funabiki H (2007) Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly. Dev Cell 12: 31-43
17. Kinoshita K, Noetzel TL, Pelletier L, Mechtler K, Drechsel DN, Schwager A, Lee M, Raff JW, Hyman AA (2005) Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis. J Cell Biol 170: 1047-1055
18. Koffa MD, Casanova CM, Santarella R, Kocher T, Wilm M, Mattaj IW (2006) HURP is part of a Ran-dependent complex involved in spindle formation. Curr Biol 16: 743-754
19. Kufer TA, Sillje HH, Korner R, Gruss OJ, Meraldi P, Nigg EA (2002) Human TPX2 is required for targeting Aurora-A kinase to the spindle. J Cell Biol 158: 617-623
20. Peset I, Seiler J, Sardon T, Bejarano LA, Rybina S, Vernos I (2005) Function and regulation of Maskin, a TACC family protein, in microtubule growth during mitosis. J Cell Biol 170: 1057-1066
21. Stenoien DL, Sen S, Mancini MA, Brinkley BR (2003) Dynamic association of a tumor amplified kinase, Aurora-A, with the centrosome and mitotic spindle. Cell Motil Cytoskeleton 55: 134-146
22. Tsai MY, Wiese C, Cao K, Martin O, Donovan P, Ruderman J, Prigent C, Zheng Y (2003) A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly. Nat Cell Biol 5: 242-248
23. Tsai MY, Zheng Y (2005) Aurora A kinase-coated beads function as microtubule-organizing centers and enhance RanGTP-induced spindle assembly. Curr Biol 15: 2156-2163
24. Zhang X, Ems-McClung SC, Walczak CE (2008) Aurora A phosphorylates MCAK to control Ran-dependent spindle bipolarity. Mol Biol Cell 19: 2752-2765