Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models

Oncogene

Volumn 23, Issue 54, 2004, Pages 8720-8730

  Zhang, Dongwei ^a   Hirota, Toru ^a   Marumoto, Tomotoshi ^a   Shimizu, Michio ^b   Kunitoku, Naoko ^a   Sasayama, Takashi ^a   Arima, Yoshimi ^a   Feng, Liping ^a   Suzuki, Misao ^c   Takeya, Motohiro ^a   Saya, Hideyuki ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Aurora A; Cre loxP; Mammary gland; Mitosis; p53

Indexed keywords

AORARA A PROTEIN; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREAST CELL; BREAST DEVELOPMENT; BREAST EPITHELIUM; BREAST HYPERPLASIA; CARCINOGENESIS; CELL NUCLEUS; CELL SURVIVAL; CONTROLLED STUDY; DISEASE MODEL; EMBRYO CELL; EPITHELIUM CELL; FEMALE; FIBROBLAST; LATENT PERIOD; MALE; MALIGNANT NEOPLASTIC DISEASE; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CELL TRANSFORMATION, NEOPLASTIC; FLUORESCENT ANTIBODY TECHNIQUE; HYPERPLASIA; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, TRANSGENIC; MITOSIS; MODELS, ANIMAL; MOLECULAR SEQUENCE DATA; PROTEIN-SERINE-THREONINE KINASES; RECOMBINASES; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; MUS MUSCULUS; RODENTIA;

EID: 9944220985     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208153     Document Type: Article

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