Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival

PLoS ONE

Volumn 3, Issue 2, 2008, Pages

  Landi, Maria Teresa ^a   Dracheva, Tatiana ^a   Rotunno, Melissa ^a   Figueroa, Jonine D ^a   Liu, Huaitian ^a   Dasgupta, Abhijit ^a   Mann, Felecia E ^a   Fukuoka, Junya ^a   Hames, Megan ^a   Bergen, Andrew W ^a   Murphy, Sharon E ^b   Yang, Ping ^c   Pesatori, Angela C ^d   Consonni, Dario ^d   Bertazzi, Pier Alberto ^d   Wacholder, Sholom ^a   Shih, Joanna H ^a   Caporaso, Neil E ^a   Jen, Jin ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c MAYO CLINIC   (United States)

^d UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; PROTEIN NEK2; PROTEIN PRC1; PROTEIN TTK;

ADULT; AGED; ANALYSIS OF VARIANCE; ARTICLE; CANCER MORTALITY; CANCER STAGING; CANCER SURVIVAL; CELL CYCLE; CIGARETTE SMOKING; CONTROLLED STUDY; EARLY CANCER; FROZEN SECTION; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; LUNG ADENOCARCINOMA; LUNG CARCINOGENESIS; LUNG PARENCHYMA; MAJOR CLINICAL STUDY; MITOSIS SPINDLE; ADENOCARCINOMA; BIOPSY; CELL TRANSFORMATION; GENE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; LUNG TUMOR; SMOKING;

NICOTIANA TABACUM;

ADENOCARCINOMA; BIOPSY; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENES, CDC; HUMANS; LUNG NEOPLASMS; SMOKING;

EID: 45749140422     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0001651     Document Type: Article

References (30)

1. Bryant A, Cerfolio RJ (2007) Differences in epidemiology, histology, and survival between cigarette and never-smokers who develop non-small cell lung cancer. Chest 132: 185-192.
2. Benjamini Y, Hochberg Y (1995) Controlling the False Discovery Rate: a practical and powerful approach to multiple testing. J Royal Stat Soc Ser B 57: 289-300.
3. Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, et al. (2000) Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 25: 25-29.
4. Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, et al. (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 102: 15545-15550.
5. Hochreiter S, Clevert DA, Obermayer K (2006) A new summarization method for Affymetrix probe level data. Bioinformatics 22: 943-949.
6. Cox D (1972) Regression models and life tables (with discussion). J Roy Stat Soc B 4: 187-220.
7. Hecht SS, Carmella SG, Chen M, Dor Koch JF, Miller AT, et al. (1999) Quantitation of urinary metabolites of a tobacco-specific lung carcinogen after smoking cessation. Cancer Res 59: 590-596.
8. Zeeberg BR, Feng W, Wang G, Wang MD, Fojo AT, et al. (2003) GoMiner: a resource for biological interpretation of genomic and proteomic data. Genome Biol 4: R28.
9. Spira A, Beane J, Shah V, Liu G, Schembri F, et al. (2004) Effects of cigarette smoke on the human airway epithelial cell transcriptome. Proc Natl Acad Sci U S A 101: 10143-10148.
10. Lampe JW, Stepaniants SB, Mao M, Radich JP, Dai H, et al. (2004) Signatures or enviromnental exposures using peripheral leukocyte gene expression: tobacco smoke. Cancer Epidemiol Biomarkers Prev 13: 445-453.
11. Petersen S, Aninat-Meyer M, Schluns K, Gellert K, Dietel M, et al. (2000) Chromosomal alterations in the clonal evolution to the metastatic stage of squamous cell carcinomas of the lung. Br J Cancer 82: 65-73.
12. Lou Y, Yao J, Zereshki A, Don Z, Ahmed K, et al. (2004) NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling. J Biol Chem 279: 20049-20057.
13. Gruss OJ, Vernos I (2004) The mechanism of spindle assembly: functions or Ran and its target TPX2. J Cell Biol 166: 949-955.
14. Tonon G, Wong KK, Maulik G, Brennan C, Feng B, et al, (2005) High-resolution genomic profiles of human lung cancer. Proc Natl Acad Sci U S A 102: 9625-9630.
15. Kufer TA, Sillje HH, Korner R, Gruss OJ, Meraldi P, et al. (2002) Human TPX2 is required for targeting Aurora-A kinase to the spindle. J Cell Biol 158: 617-623.
16. Keen N, Taylor S (2004) Aurora-kinase inhibitors as anticancer agents. Nat Rev Cancer 4: 927-936.
17. Baonza A, Murawsky CM, Travers AA, Freeman M (2002) Pointed and Tramtrack69 establish an EGFR-dependent transcriptional switch to regulate mitosis. Nat Cell Biol 4: 976-980.
18. Shama SV, Bell DW, Settleman J, Haber DA (2007) Epidermal growth factor receptor mutations in lung cancer. Nat Rev Cancer 7: 169-181.
19. Goga A, Yang D, Tward AD, Morgan DO, Bishop JM (2007) Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC. Nat Med 13: 820-827.
20. Santaranada A, Neef R, Eberspacher U, Eis K, Husemann M, et al. (2007) Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis. Mol Biol Cell 18: 4024-4036.
21. Perez dC, I, de CG, Malumbres M (2007) A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy. Carcinogenesis 28: 899-912.
22. Borczuk AC, Powell CA (2007) Expression profiling and lung cancer development. Proc, Am Thorac Soc 4: 127-132.
23. Lerman MI, Minna JD (2000) The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p2l.3 Tumor Suppressor Gene Consortium. Cancer Res 60: 6116-6133.
24. Wistuba H, Behrens C, Virmani AK, Mele G, Milchgrub S, et al. (2000) High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints. Cancer Res 60: 1949-1960.
25. Woodruff PG, Koth LL, Yang YH, Rodriguez MW, Favoreto, S, et al. (2005) A distinctive alveolar macrophage activation state induced by cigarette smoking. Am J Respir Crit Care Med 172: 1383-1392.
26. Heguy A, O'Connor TP, Luettich K, Worgall S, Cieciuch A, et al. (2006) Gene expression profiling of human alveolar macrophages of phenotypically normal smokers and nonsmokers reveals a previously unrecognized subset of genes modulated by cigarette smoking. J Mol Med 84: 318-328.
27. Harvey BG, Heguy A, Leopold PL, Carolan BJ, Ferris B, et al. (2007) Modification of gene expression of the small airway epithelium in response to cigarette smoking. J Mol Med 85: 39-53.
28. Powell CA, Spira A, Derti A, DeLisi C, Liu G, et al. (2003) Gene expression in lung adenocarcinomas of smokers and nonsmokers. Am J Respir Cell Mol Biol 29: 157-162.
29. Miura K, Bowman ED, Simon R, Peng AC, Robles AI, et al. (2002) Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles. Cancer Res 62: 3244-3250.
30. Woenckhaus M, Klein-Hitpass L, Grepmeier U, Merk J, Pfeifer M, et al. (2006) Smoking and cancer-related gene expression in bronchial epithelium and non-small-cell lung cancers. J Pathol 210: 192-204.