Pdx-1-driven overexpression of aurora a kinase induces mild ductal dysplasia of pancreatic ducts near islets in transgenic mice

Pancreas

Volumn 37, Issue 3, 2008, Pages

  Warner, Steven L ^a   Muñoz, Ruben M ^b   Bearss, David J ^c   Grippo, Paul ^d   Han, Haiyong ^b   Von Hoff, Daniel D ^b,d  

^a UNIVERSITY OF ARIZONA   (United States)

^b TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Aurora A kinase; Pancreatic adenocarcinoma; Transgenic mouse model

Indexed keywords

AURORA A KINASE; TRANSCRIPTION FACTOR PDX 1; AURKA PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; INSULIN PROMOTER FACTOR 1; PROTEIN SERINE THREONINE KINASE; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL HYPERPLASIA; CONTROLLED STUDY; DISEASE COURSE; GENE; GENE MUTATION; HISTOLOGY; INTROSPECTION; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PANCREAS; PANCREAS ADENOCARCINOMA; PANCREAS DISEASE; PANCREAS DUCT DYSPLASIA; PANCREAS ISLET; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TRANSGENIC MOUSE; ANIMAL; C3H MOUSE; C57BL MOUSE; ENZYMOLOGY; GENETICS; HUMAN; HYPERPLASIA; LYMPHOCYTE; METABOLISM; PANCREAS DUCT; PATHOLOGY;

ANIMALS; HOMEODOMAIN PROTEINS; HUMANS; HYPERPLASIA; ISLETS OF LANGERHANS; LYMPHOCYTES; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; PANCREATIC DUCTS; PROMOTER REGIONS, GENETIC; PROTEIN-SERINE-THREONINE KINASES; TRANS-ACTIVATORS;

EID: 58149329013     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPA.0b013e318176b9ae     Document Type: Article

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