메뉴 건너뛰기




Volumn 15, Issue 21, 2009, Pages 6519-6528

Validation of TPX2 as a potential therapeutic target in pancreatic cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN; PACLITAXEL; PROTEIN TPX2; UNCLASSIFIED DRUG;

EID: 70350743121     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-09-0077     Document Type: Article
Times cited : (97)

References (26)
  • 2
    • 23244467697 scopus 로고    scopus 로고
    • Genomewide aberrations in pancreatic adenocarcinoma
    • Nowak NJ, Gaile D, Conroy JM, et al. Genomewide aberrations in pancreatic adenocarcinoma. Cancer Genet Cytogenet 2005;161:36-50.
    • (2005) Cancer Genet Cytogenet , vol.161 , pp. 36-50
    • Nowak, N.J.1    Gaile, D.2    Conroy, J.M.3
  • 3
    • 33746905089 scopus 로고    scopus 로고
    • AURKA is one of the downstream targets of MAPK1/ERK2 in pancreatic cancer
    • DOI 10.1038/sj.onc.1209494, PII 1209494
    • Furukawa T, Kanai N, Shiwaku HO, Soga N, Uehara A, Horii A. AURKA is one of the downstream targets of MAPK1/ERK2 in pancreatic cancer. Oncogene 2006;25:4831-4839 (Pubitemid 44201174)
    • (2006) Oncogene , vol.25 , Issue.35 , pp. 4831-4839
    • Furukawa, T.1    Kanai, N.2    Shiwaku, H.O.3    Soga, N.4    Uehara, A.5    Horii, A.6
  • 4
    • 33846492895 scopus 로고    scopus 로고
    • Identification of genetic alterations in pancreatic cancer by the combined use of tissue microdissection and array-based comparative genomic hybridisation
    • DOI 10.1038/sj.bjc.6603563, PII 6603563
    • Harada T, Baril P, Gangeswaran R, et al. Identification of genetic alterations in pancreatic cancer by the combineduse of tissue microdissection and array-based comparative genomic hybridisation. Br J Cancer 2007;96: 373-382 (Pubitemid 46160645)
    • (2007) British Journal of Cancer , vol.96 , Issue.2 , pp. 373-382
    • Harada, T.1    Baril, P.2    Gangeswaran, R.3    Kelly, G.4    Chelala, C.5    Bhakta, V.6    Caulee, K.7    Mahon, P.C.8    Lemoine, N.R.9
  • 5
    • 47349090074 scopus 로고    scopus 로고
    • Genomewide DNA copy number analysis in pancreatic cancer using high-density single nucleotide polymorphism arrays
    • Harada T, Chelala C, Bhakta V, et al. Genomewide DNA copy number analysis in pancreatic cancer using high-density single nucleotide polymorphism arrays. Oncogene 2007.
    • (2007) Oncogene
    • Harada, T.1    Chelala, C.2    Bhakta, V.3
  • 9
    • 33750885958 scopus 로고    scopus 로고
    • TPX2 expression andits significance in squamous cell carcinoma of lung
    • Lin DM, Ma Y, Xiao T, et al. [TPX2 expression andits significance in squamous cell carcinoma of lung]. Zhonghua Bing Li Xue Za Zhi 2006;35: 540-544
    • (2006) Zhonghua Bing Li Xue Za Zhi , vol.35 , pp. 540-544
    • Lin, D.M.1    Ma, Y.2    Xiao, T.3
  • 10
    • 33748491903 scopus 로고    scopus 로고
    • 20q11.1 amplification in giant-cell tumor of bone: Array CGH, FISH, and association with outcome
    • Smith LT, Mayerson J, Nowak NJ, et al. 20q11.1 amplification in giant-cell tumor of bone: array CGH, FISH, and association with outcome. Genes Chromosomes Cancer 2006; 45:957-966
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 957-966
    • Smith, L.T.1    Mayerson, J.2    Nowak, N.J.3
  • 11
    • 4644233153 scopus 로고    scopus 로고
    • The mechanism of spindle assembly: Functions of Ran and its target TPX2
    • DOI 10.1083/jcb.200312112
    • Gruss OJ, Vernos I. The mechanism of spindle assembly: functions of Ran andits target TPX2. J Cell Biol 2004;166:949-955 (Pubitemid 39304757)
    • (2004) Journal of Cell Biology , vol.166 , Issue.7 , pp. 949-955
    • Gruss, O.J.1    Vernos, I.2
  • 12
    • 17744380396 scopus 로고    scopus 로고
    • Ran induces spindle assembly by reversing the inhibitory effect of importin α on TPX2 activity
    • Gruss OJ, Carazo-Salas RE, Schatz CA, et al. Ran induces spindle assembly by reversing the inhibitory effect of importin α on TPX2 activity. Cell 2001;104:83-93.
    • (2001) Cell , vol.104 , pp. 83-93
    • Gruss, O.J.1    Carazo-Salas, R.E.2    Schatz, C.A.3
  • 14
    • 4644265572 scopus 로고    scopus 로고
    • Determinants for Aurora-A activation and Aurora-B discrimination by TPX2
    • Bayliss R, Sardon T, Ebert J, Lindner D, Vernos I, Conti E. Determinants for Aurora-A activation andAuro ra-B discrimination by TPX2. Cell Cycle 2004;3:404-407 (Pubitemid 40278221)
    • (2004) Cell Cycle , vol.3 , Issue.4 , pp. 404-407
    • Bayliss, R.1    Sardon, T.2    Ebert, J.3    Lindner, D.4    Vernos, I.5    Conti, E.6
  • 16
    • 0032894224 scopus 로고    scopus 로고
    • Quantitative RT-PCR: Pitfalls andpotential
    • 24-25
    • Freeman WM, Walker SJ, Vrana KE. Quantitative RT-PCR: pitfalls andpotential. Biotechniques 1999;26:112-22, 24-25
    • (1999) Biotechniques , vol.26 , pp. 112-122
    • Freeman, W.M.1    Walker, S.J.2    Vrana, K.E.3
  • 18
    • 0016738010 scopus 로고
    • Rapidflow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining
    • Krishan A. Rapidflow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining. J Cell Biol 1975;66:188-193
    • (1975) J Cell Biol , vol.66 , pp. 188-193
    • Krishan, A.1
  • 20
    • 16844366286 scopus 로고    scopus 로고
    • RNA interference targeting aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells
    • DOI 10.1158/0008-5472.CAN-04-3981
    • Hata T, Furukawa T, Sunamura M, et al. RNA interference targeting aurora kinase a suppresses tumor growth andenhances the taxane chemosensitivity in human pancreatic cancer cells. Cancer Res 2005;65:2899-2905 (Pubitemid 40490094)
    • (2005) Cancer Research , vol.65 , Issue.7 , pp. 2899-2905
    • Hata, T.1    Furukawa, T.2    Sunamura, M.3    Egawa, S.4    Motoi, F.5    Ohmura, N.6    Marumoto, T.7    Saya, H.8    Horii, A.9
  • 21
    • 58149496571 scopus 로고    scopus 로고
    • Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells
    • Scharer CD, Laycock N, Osunkoya AO, et al. Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells. J Transl Med2008;6:79.
    • (2008) J Transl Med , vol.6 , pp. 79
    • Scharer, C.D.1    Laycock, N.2    Osunkoya, A.O.3
  • 22
    • 33749605644 scopus 로고    scopus 로고
    • Aurora-A induces cell survival and chemoresistance by activation of Akt through a p53-dependent manner in ovarian cancer cells
    • DOI 10.1002/ijc.22154
    • Yang H, He L, Kruk P, Nicosia SV, Cheng JQ. Aurora-A induces cell survival and chemoresistance by activation of Akt through a p53- dependent manner in ovarian cancer cells. Int J Cancer 2006;119:2304-2312 (Pubitemid 44546949)
    • (2006) International Journal of Cancer , vol.119 , Issue.10 , pp. 2304-2312
    • Yang, H.1    He, L.2    Kruk, P.3    Nicosia, S.V.4    Cheng, J.Q.5
  • 23
    • 34249285532 scopus 로고    scopus 로고
    • Identification of Ras-related nuclear protein, targeting protein for Xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen
    • DOI 10.1158/0008-5472.CAN-06-4132
    • Morgan-Lappe SE, Tucker LA, Huang X, et al. Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, andst earoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen. Cancer Res 2007;67:4390-4398 (Pubitemid 46815088)
    • (2007) Cancer Research , vol.67 , Issue.9 , pp. 4390-4398
    • Morgan-Lappe, S.E.1    Tucker, L.A.2    Huang, X.3    Zhang, Q.4    Sarthy, A.V.5    Zakula, D.6    Vernetti, L.7    Schurdak, M.8    Wang, J.9    Fesik, S.W.10
  • 24
    • 49649120123 scopus 로고    scopus 로고
    • Chromosome 20q amplification regulates in vitro response to Kinesin-5 inhibitor
    • Jackson AL, Mao M, Kobayashi S, et al. Chromosome 20q amplification regulates in vitro response to Kinesin-5 inhibitor. Cancer Inform 2008;6:147-164
    • (2008) Cancer Inform , vol.6 , pp. 147-164
    • Jackson, A.L.1    Mao, M.2    Kobayashi, S.3
  • 25
    • 0037446847 scopus 로고    scopus 로고
    • A novel mechanism for activation of the protein kinase Aurora a
    • DOI 10.1016/S0960-9822(03)00166-0
    • Eyers PA, Erikson E, Chen LG, Maller JL. A novel mechanism for activation of the protein kinase Aurora A. Curr Biol 2003;13:691-697 (Pubitemid 36453320)
    • (2003) Current Biology , vol.13 , Issue.8 , pp. 691-697
    • Eyers, P.A.1    Erikson, E.2    Chen, L.G.3    Maller, J.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.