Cannabinoid receptor 1 mediates palmitic acid-induced apoptosis via endoplasmic reticulum stress in human renal proximal tubular cells

Journal of Cellular Physiology

Volumn 225, Issue 3, 2010, Pages 654-663

  Lim, J C ^a   Lim, S K ^a   Han, H J ^a   Park, S H ^a  

^a Chonnam National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; ACTIVATING TRANSCRIPTION FACTOR 4; ARACHIDONYL TRIFLUOROMETHYL KETONE; BETA ACTIN; CANNABINOID 1 RECEPTOR; CASPASE 3; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ENDOCANNABINOID; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INDOMETACIN; INITIATION FACTOR 2ALPHA; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PALMITIC ACID; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; PROTEIN PERK; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ATF4 PROTEIN, HUMAN; BAX PROTEIN, HUMAN; CASP3 PROTEIN, HUMAN; CYCLOOXYGENASE 2 INHIBITOR; CYTOSOLIC PHOSPHOLIPASE A2; DDIT3 PROTEIN, HUMAN; ENZYME INHIBITOR; HEAT SHOCK PROTEIN; INITIATION FACTOR 2; MOLECULAR CHAPERONE GRP78; PERK KINASE; PROTEIN KINASE R;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYPERLIPIDEMIA; INTERNALIZATION; KIDNEY PROXIMAL TUBULE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; CELL PROLIFERATION; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGICAL STRESS; RNA INTERFERENCE; TIME;

ACTIVATING TRANSCRIPTION FACTOR 4; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL PROLIFERATION; CYCLOOXYGENASE 2 INHIBITORS; DIABETIC NEPHROPATHIES; DOSE-RESPONSE RELATIONSHIP, DRUG; EIF-2 KINASE; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; EUKARYOTIC INITIATION FACTOR-2; HEAT-SHOCK PROTEINS; HUMANS; HYPERLIPIDEMIAS; KIDNEY TUBULES, PROXIMAL; PALMITIC ACID; PHOSPHOLIPASES A2, CYTOSOLIC; PHOSPHORYLATION; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTOR, CANNABINOID, CB1; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TIME FACTORS; TRANSCRIPTION FACTOR CHOP;

EID: 77957747104     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22255     Document Type: Article

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