High glucose down-regulates angiotensin II binding via the PKC-MAPK-cPLA2 signal cascade in renal proximal tubule cells

Kidney International

Volumn 61, Issue 3, 2002, Pages 913-925

  Soo, Hyun Park ^a,b   Chang, Hoon Woo ^a,b   Jae, Hong Kim ^a,b   Jang, Hern Lee ^a,b   Il, Suk Yang ^a,b   Kwon, Moo Park ^a,b   Ho, Jae Han ^a,b  

^a Chonnam National University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Angiotensin II receptor; Cell signaling; Diabetic nephropathy; Glucose; Kidney; Mitogen activated protein kinase; Phospholipase A2; Protein kinase C

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANGIOTENSIN II I 125; ANGIOTENSIN RECEPTOR; ARACHIDONIC ACID; GLUCOSE; IBUPROFEN; INDOMETACIN; MEPACRINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; TRITIUM;

ANIMAL CELL; CONFERENCE PAPER; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN BINDING; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SIGNAL TRANSDUCTION;

EID: 0036183786     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2002.00204.x     Document Type: Article

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