Role of GRP78/BiP degradation and ER stress in deoxynivalenol-induced interleukin-6 upregulation in the macrophage

Toxicological Sciences

Volumn 109, Issue 2, 2009, Pages 247-255

  Shi, Yuhui ^a,b   Porter, Katie ^b   Parameswaran, Narayanan ^c   Bae, Hee Kyong ^a,b   Pestka, James J ^a,b,c  

^a Michigan State University   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c NONE   (United States)

Author keywords

Deoxynivalenol (DON); ER stress, translation inhibition; Interleukin 6

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CALPAIN; CATHEPSIN; CHAPERONE; GLUCOSE REGULATED PROTEIN 78; INTERLEUKIN 6; MESSENGER RNA; PROTEASOME; RICIN; RORIDIN; SATRATOXIN G; T 2 TOXIN; UNCLASSIFIED DRUG; VOMITOXIN; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; CYTOTOXICITY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE EXPRESSION REGULATION; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; RNA INTERFERENCE; UPREGULATION;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; ENDOPLASMIC RETICULUM; FEMALE; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; INTERLEUKIN-6; MACROPHAGES, PERITONEAL; MICE; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TRICHOTHECENES; UP-REGULATION;

MURINAE;

EID: 66149128432     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfp060     Document Type: Article

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