Inhibition of cyclic nucleotide phosphodiesterases by methylxanthines and related compounds

Handbook of Experimental Pharmacology

Volumn 200, Issue , 2011, Pages 93-133

  Francis, Sharron H ^a   Sekhar, Konjeti R ^a   Ke, Hengming ^b   Corbin, Jackie D ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Caffeine; Caffeine in beverages and foods; Cyclic AMP; Cyclic GMP; Phosphodiesterase inhibitors; Phosphodiesterases; Theophylline; Xanthine

Indexed keywords

ADENOCIRCA; CAFFEINE; CYCLIC AMP; CYCLIC GMP; CYCLIC NUCLEOTIDE; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; METHYLXANTHINE DERIVATIVE; PENTOXIFYLLINE; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL; TADALAFIL; THEOPHYLLINE; UNCLASSIFIED DRUG; VARDENAFIL; XANTHINE DERIVATIVE;

ANTIINFLAMMATORY ACTIVITY; ASTHMA; BINDING SITE; BRONCHOSPASM; CHRONIC OBSTRUCTIVE LUNG DISEASE; DRUG BLOOD LEVEL; DRUG COST; DRUG DESIGN; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ERECTILE DYSFUNCTION; HUMAN; INTERMITTENT CLAUDICATION; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; REVIEW; SITE DIRECTED MUTAGENESIS; UNSPECIFIED SIDE EFFECT; X RAY CRYSTALLOGRAPHY;

3',5'-CYCLIC-AMP PHOSPHODIESTERASES; 3',5'-CYCLIC-GMP PHOSPHODIESTERASES; ANIMALS; CAFFEINE; CATALYTIC DOMAIN; DRUG DESIGN; HUMANS; PHOSPHODIESTERASE INHIBITORS; THEOPHYLLINE; XANTHINES;

EID: 77957596953     PISSN: 01712004     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-13443-2_4     Document Type: Review

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