-
1
-
-
17644370061
-
Leucine zipper-mediated homo-oligomerization regulates the Rho-GEF activity of AKAP-Lbc
-
Baisamy, L., N. Jurisch, and D. Diviani. 2005. Leucine zipper-mediated homo-oligomerization regulates the Rho-GEF activity of AKAP-Lbc. J. Biol. Chem. 280:15405-15412.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 15405-15412
-
-
Baisamy, L.1
Jurisch, N.2
Diviani, D.3
-
2
-
-
0036302962
-
Negative regulation of rho signaling by insulin and its impact on actin on cytoskeleton organization in vascular smooth muscle cells: Role of nitric oxide and cyclic guanosine monophosphate signaling pathways
-
Begum, N., O. A. Sandu, and N. Duddy. 2002. Negative regulation of rho signaling by insulin and its impact on actin on cytoskeleton organization in vascular smooth muscle cells: role of nitric oxide and cyclic guanosine monophosphate signaling pathways. Diabetes 51:2256-2263.
-
(2002)
Diabetes
, vol.51
, pp. 2256-2263
-
-
Begum, N.1
Sandu, O.A.2
Duddy, N.3
-
3
-
-
0037155132
-
Active Rho kinase (ROK-alpha) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells
-
Begum, N., O. A. Sandu, M. Ito, S. M. Lohmann, and A. Smolenski. 2002. Active Rho kinase (ROK-alpha) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells. J. Biol. Chem. 277:6214-6222.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 6214-6222
-
-
Begum, N.1
Sandu, O.A.2
Ito, M.3
Lohmann, S.M.4
Smolenski, A.5
-
4
-
-
17944363488
-
Activation of extracellular signal-regulated kinases and CREB/ATF-1 mediate the expression of CCAAT/enhancer binding proteins β and -δ in preadipocytes
-
Belmonte, N., B. W. Phillips, F. Massiera, P. Villageois, B. Wdziekonski, P. Saint-Marc, J. Nichols, J. Aubert, K. Saeki, A. Yuo, S. Narumiya, G. Ailhaud, and C. Dani. 2001. Activation of extracellular signal-regulated kinases and CREB/ATF-1 mediate the expression of CCAAT/enhancer binding proteins β and -δ in preadipocytes. Mol. Endocrinol. 15:2037-2049.
-
(2001)
Mol. Endocrinol
, vol.15
, pp. 2037-2049
-
-
Belmonte, N.1
Phillips, B.W.2
Massiera, F.3
Villageois, P.4
Wdziekonski, B.5
Saint-Marc, P.6
Nichols, J.7
Aubert, J.8
Saeki, K.9
Yuo, A.10
Narumiya, S.11
Ailhaud, G.12
Dani, C.13
-
5
-
-
0037163113
-
Regulation of Wnt signaling during adipogenesis
-
Bennett, C. N., S. E. Ross, K. A. Longo, L. Bajnok, N. Hemati, K. W. Johnson, S. D. Harrison, and O. A. MacDougald. 2002. Regulation of Wnt signaling during adipogenesis. J. Biol. Chem. 277:30998-31004.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 30998-31004
-
-
Bennett, C.N.1
Ross, S.E.2
Longo, K.A.3
Bajnok, L.4
Hemati, N.5
Johnson, K.W.6
Harrison, S.D.7
MacDougald, O.A.8
-
6
-
-
33751241720
-
Epac proteins: Multi-purpose cAMP targets
-
Bos, J. L. 2006. Epac proteins: multi-purpose cAMP targets. Trends Biochem. Sci. 31:680-686.
-
(2006)
Trends Biochem. Sci
, vol.31
, pp. 680-686
-
-
Bos, J.L.1
-
7
-
-
24344439701
-
Adrenaline potentiates insulin-stimulated PKB activation via cAMP and Epac: Implications for cross talk between insulin and adrenaline
-
Brennesvik, E. O., C. Ktori, J. Ruzzin, E. Jebens, P. R. Shepherd, and J. Jensen. 2005. Adrenaline potentiates insulin-stimulated PKB activation via cAMP and Epac: implications for cross talk between insulin and adrenaline. Cell. Signal. 17:1551-1559.
-
(2005)
Cell. Signal
, vol.17
, pp. 1551-1559
-
-
Brennesvik, E.O.1
Ktori, C.2
Ruzzin, J.3
Jebens, E.4
Shepherd, P.R.5
Jensen, J.6
-
8
-
-
0028787753
-
Multiple protein kinase A-regulated events are required for transcriptional induction by cAMP
-
Brindle, P., T. Nakajima, and M. Montminy. 1995. Multiple protein kinase A-regulated events are required for transcriptional induction by cAMP. Proc. Natl. Acad. Sci. USA 92:10521-10525.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 10521-10525
-
-
Brindle, P.1
Nakajima, T.2
Montminy, M.3
-
9
-
-
28544434037
-
Modulation of muscle regeneration, myogenesis, and adipogenesis by the Rho family guanine nucleotide exchange factor GEFT
-
Bryan, B. A., D. C. Mitchell, L. Zhao, W. Ma, L. J. Stafford, B.-B. Teng, and M. Liu. 2005. Modulation of muscle regeneration, myogenesis, and adipogenesis by the Rho family guanine nucleotide exchange factor GEFT. Mol. Cell. Biol. 25:11089-11101.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 11089-11101
-
-
Bryan, B.A.1
Mitchell, D.C.2
Zhao, L.3
Ma, W.4
Stafford, L.J.5
Teng, B.-B.6
Liu, M.7
-
10
-
-
0026050219
-
Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells
-
Cao, Z., R. Umek, and S. McKnight. 1991. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev. 5:1538-1552.
-
(1991)
Genes Dev
, vol.5
, pp. 1538-1552
-
-
Cao, Z.1
Umek, R.2
McKnight, S.3
-
11
-
-
33845868011
-
TC10alpha is required for insulin-stimulated glucose uptake in adipocytes
-
Chang, L., S. H. Chiang, and A. R. Saltiel. 2007. TC10alpha is required for insulin-stimulated glucose uptake in adipocytes. Endocrinology 148:27-33.
-
(2007)
Endocrinology
, vol.148
, pp. 27-33
-
-
Chang, L.1
Chiang, S.H.2
Saltiel, A.R.3
-
12
-
-
0035184080
-
CREB/CBP and SRE-interacting transcriptional regulators are fast on-off switches: Duration of calcium transients specifies the magnitude of transcriptional responses
-
Chawla, S., and H. Bading. 2001. CREB/CBP and SRE-interacting transcriptional regulators are fast on-off switches: duration of calcium transients specifies the magnitude of transcriptional responses. J. Neurochem. 79:849-858.
-
(2001)
J. Neurochem
, vol.79
, pp. 849-858
-
-
Chawla, S.1
Bading, H.2
-
13
-
-
0035912228
-
Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10
-
Chiang, S. H., C. A. Baumann, M. Kanzaki, D. C. Thurmond, R. T. Watson, C. L. Neudauer, I. G. Macara, J. E. Pessin, and A. R. Saltiel. 2001. Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10. Nature 410:944-948.
-
(2001)
Nature
, vol.410
, pp. 944-948
-
-
Chiang, S.H.1
Baumann, C.A.2
Kanzaki, M.3
Thurmond, D.C.4
Watson, R.T.5
Neudauer, C.L.6
Macara, I.G.7
Pessin, J.E.8
Saltiel, A.R.9
-
14
-
-
4344566719
-
Cyclic nucleotide analogs
-
R. Bradshaw and E. Dennis ed, Academic Press, San Diego, CA
-
Christensen, A. E., and S. O. Doskeland. 2003. Cyclic nucleotide analogs, p. 549-554. In R. Bradshaw and E. Dennis (ed.), Handbook of cell signaling, vol. 2. Academic Press, San Diego, CA.
-
(2003)
Handbook of cell signaling
, vol.2
, pp. 549-554
-
-
Christensen, A.E.1
Doskeland, S.O.2
-
15
-
-
0041315574
-
cAMP analog mapping of Epac1 and cAMP kinase: Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension
-
Christensen, A. E., F. Selheim, J. de Rooij, S. Dremier, F. Schwede, K. K. Dao, A. Martinez, C. Maenhaut, J. L. Bos, H. G. Genieser, and S. O. Doskeland. 2003. cAMP analog mapping of Epac1 and cAMP kinase: discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension. J. Biol. Chem. 278:35394-35402.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 35394-35402
-
-
Christensen, A.E.1
Selheim, F.2
de Rooij, J.3
Dremier, S.4
Schwede, F.5
Dao, K.K.6
Martinez, A.7
Maenhaut, C.8
Bos, J.L.9
Genieser, H.G.10
Doskeland, S.O.11
-
16
-
-
0026029709
-
CCAAT/enhancer binding protein gene promoter: Binding of nuclear factors during differentiation of 3T3-L1 preadipocytes
-
Christy, R. J., K. H. Kaestner, D. E. Geiman, and M. D. Lane. 1991. CCAAT/enhancer binding protein gene promoter: binding of nuclear factors during differentiation of 3T3-L1 preadipocytes. Proc. Natl. Acad. Sci. USA 88:2593-2597.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 2593-2597
-
-
Christy, R.J.1
Kaestner, K.H.2
Geiman, D.E.3
Lane, M.D.4
-
17
-
-
14944377651
-
Regulation of vascular endothelial barrier function by Epac, a cAMP activated exchange factor for Rap GTPase
-
Cullere, X., S. K. Shaw, L. Andersson, J. Hirahashi, F. W. Luscinskas, and T. N. Mayadas. 2004. Regulation of vascular endothelial barrier function by Epac, a cAMP activated exchange factor for Rap GTPase. Blood 105:1950-1955.
-
(2004)
Blood
, vol.105
, pp. 1950-1955
-
-
Cullere, X.1
Shaw, S.K.2
Andersson, L.3
Hirahashi, J.4
Luscinskas, F.W.5
Mayadas, T.N.6
-
18
-
-
33746859372
-
Cyclic AMP-dependent and Epac-mediated activation of R-Ras by G protein-coupled receptors leads to phospholipase D stimulation
-
De Jesus, M. L., M. B. Stope, P. A. O. Weernink, Y. Mahlke, C. Borgermann, V. N. Ananaba, C. Rimmbach, D. Rosskopf, M. C. Michel, K. H. Jakobs, and M. Schmidt. 2006. Cyclic AMP-dependent and Epac-mediated activation of R-Ras by G protein-coupled receptors leads to phospholipase D stimulation. J. Biol. Chem. 281:21837-21847.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 21837-21847
-
-
De Jesus, M.L.1
Stope, M.B.2
Weernink, P.A.O.3
Mahlke, Y.4
Borgermann, C.5
Ananaba, V.N.6
Rimmbach, C.7
Rosskopf, D.8
Michel, M.C.9
Jakobs, K.H.10
Schmidt, M.11
-
19
-
-
0032480888
-
Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP
-
de Rooij, J., F. J. T. Zwartkruis, M. H. G. Verheijen, R. H. Cool, S. M. B. Nijman, A. Wittinghofer, and J. L. Bos. 1998. Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP. Nature 396:474-477.
-
(1998)
Nature
, vol.396
, pp. 474-477
-
-
de Rooij, J.1
Zwartkruis, F.J.T.2
Verheijen, M.H.G.3
Cool, R.H.4
Nijman, S.M.B.5
Wittinghofer, A.6
Bos, J.L.7
-
20
-
-
3543020962
-
Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex
-
Diviani, D., L. Abuin, S. Cotecca, and L. Pansier. 2004. Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex. EMBO J. 23:2811-2820.
-
(2004)
EMBO J
, vol.23
, pp. 2811-2820
-
-
Diviani, D.1
Abuin, L.2
Cotecca, S.3
Pansier, L.4
-
21
-
-
0032575667
-
cAMP-induced morphological changes are counteracted by the activated RhoA small GTPase and the Rho kinase ROKalpha
-
Dong, J. M., T. Leung, E. Manser, and L. Lim. 1998. cAMP-induced morphological changes are counteracted by the activated RhoA small GTPase and the Rho kinase ROKalpha. J. Biol. Chem. 273:22554-22562.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 22554-22562
-
-
Dong, J.M.1
Leung, T.2
Manser, E.3
Lim, L.4
-
22
-
-
0023754127
-
Use of antibody-sepharose columns to study hormonal activation of cAMP-dependent protein kinase isozymes
-
Ekanger, R., and S. O. Døskeland. 1988. Use of antibody-sepharose columns to study hormonal activation of cAMP-dependent protein kinase isozymes. Methods Enzymol. 159:97-104.
-
(1988)
Methods Enzymol
, vol.159
, pp. 97-104
-
-
Ekanger, R.1
Døskeland, S.O.2
-
23
-
-
85006314494
-
A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK
-
Enserink, J. M., A. E. Christensen, J. de Rooij, M. van Triest, F. Schwede, H. G. Genieser, S. O. Doskeland, J. L. Blank, and J. L. Bos. 2002. A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK. Nat. Cell Biol. 4:901-906.
-
(2002)
Nat. Cell Biol
, vol.4
, pp. 901-906
-
-
Enserink, J.M.1
Christensen, A.E.2
de Rooij, J.3
van Triest, M.4
Schwede, F.5
Genieser, H.G.6
Doskeland, S.O.7
Blank, J.L.8
Bos, J.L.9
-
24
-
-
7244242394
-
The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the α3β1 integrin but not the α6β4 integrin
-
Enserink, J. M., L. S. Price, T. Methi, M. Mahic, A. Sonnenberg, J. L. Bos, and K. Tasken. 2004. The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the α3β1 integrin but not the α6β4 integrin. J. Biol. Chem. 279:44889-44896.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 44889-44896
-
-
Enserink, J.M.1
Price, L.S.2
Methi, T.3
Mahic, M.4
Sonnenberg, A.5
Bos, J.L.6
Tasken, K.7
-
25
-
-
33748942837
-
Transcriptional control of adipocyte formation
-
Farmer, S. R. 2006. Transcriptional control of adipocyte formation. Cell Metab. 4:263-273.
-
(2006)
Cell Metab
, vol.4
, pp. 263-273
-
-
Farmer, S.R.1
-
26
-
-
33846005868
-
Depletion of cAMP-response element binding protein/ATF1 inhibits adipogenic conversion of 3T3-L1 cells ectopically expressing CCAAT/enhancer binding protein (C/EBP) alpha, C/EBP beta or PPAR gamma 2
-
Fox, K. E., D. M. Fankell, P. F. Erickson, S. M. Majka, J. T. Crossno, Jr., and D. J. Klemm. 2006. Depletion of cAMP-response element binding protein/ATF1 inhibits adipogenic conversion of 3T3-L1 cells ectopically expressing CCAAT/enhancer binding protein (C/EBP) alpha, C/EBP beta or PPAR gamma 2. J. Biol. Chem. 281:40341-40353.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 40341-40353
-
-
Fox, K.E.1
Fankell, D.M.2
Erickson, P.F.3
Majka, S.M.4
Crossno Jr., J.T.5
Klemm, D.J.6
-
27
-
-
25144500035
-
Role of Rho-kinase in regulation of insulin action and glucose homeostasis
-
Furukawa, N., P. Ongusaha, W. J. Jahng, K. Araki, C. S. Choi, H. J. Kim, Y. H. Lee, K. Kaibuchi, B. B. Kahn, H. Masuzaki, J. K. Kim, S. W. Lee, and Y. B. Kim. 2005. Role of Rho-kinase in regulation of insulin action and glucose homeostasis. Cell Metab. 2:119-129.
-
(2005)
Cell Metab
, vol.2
, pp. 119-129
-
-
Furukawa, N.1
Ongusaha, P.2
Jahng, W.J.3
Araki, K.4
Choi, C.S.5
Kim, H.J.6
Lee, Y.H.7
Kaibuchi, K.8
Kahn, B.B.9
Masuzaki, H.10
Kim, J.K.11
Lee, S.W.12
Kim, Y.B.13
-
28
-
-
0024445798
-
Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
-
Gonzalez, G., and M. Montminy. 1989. Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell 59:675-680.
-
(1989)
Cell
, vol.59
, pp. 675-680
-
-
Gonzalez, G.1
Montminy, M.2
-
29
-
-
0035947729
-
A role for C/EBPbeta in regulating peroxisome proliferator-activated receptor gamma activity during adipogenesis in 3T3-L1 preadipocytes
-
Hamm, J. K., B. H. Park, and S. R. Farmer. 2001. A role for C/EBPbeta in regulating peroxisome proliferator-activated receptor gamma activity during adipogenesis in 3T3-L1 preadipocytes. J. Biol. Chem. 276:18464-18471.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 18464-18471
-
-
Hamm, J.K.1
Park, B.H.2
Farmer, S.R.3
-
30
-
-
33748366392
-
Regulatory circuits controlling white versus brown adipocyte differentiation
-
Hansen, J. B., and K. Kristiansen. 2006. Regulatory circuits controlling white versus brown adipocyte differentiation. Biochem. J. 398:153-168.
-
(2006)
Biochem. J
, vol.398
, pp. 153-168
-
-
Hansen, J.B.1
Kristiansen, K.2
-
31
-
-
0037135552
-
Deregulated MAPK activity prevents adipocyte differentiation of fibroblasts lacking the retinoblastoma protein
-
Hansen, J. B., R. K. Petersen, C. Jorgensen, and K. Kristiansen. 2002. Deregulated MAPK activity prevents adipocyte differentiation of fibroblasts lacking the retinoblastoma protein. J. Biol. Chem. 277:26335-26339.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 26335-26339
-
-
Hansen, J.B.1
Petersen, R.K.2
Jorgensen, C.3
Kristiansen, K.4
-
32
-
-
0035793577
-
Peroxisome proliferator-activated receptor delta (PPARdelta)-mediated regulation of preadipocyte proliferation and gene expression is dependent on cAMP signaling
-
Hansen, J. B., H. Zhang, T. H. Rasmussen, R. K. Petersen, E. N. Flindt, and K. Kristiansen. 2001. Peroxisome proliferator-activated receptor delta (PPARdelta)-mediated regulation of preadipocyte proliferation and gene expression is dependent on cAMP signaling. J. Biol. Chem. 276:3175-3182.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 3175-3182
-
-
Hansen, J.B.1
Zhang, H.2
Rasmussen, T.H.3
Petersen, R.K.4
Flindt, E.N.5
Kristiansen, K.6
-
33
-
-
0141780889
-
Activation of JNK by Epac is independent of its activity as a Rap guanine nucleotide exchanger
-
Hochbaum, D., T. Tanos, F. Ribeiro-Neto, D. Altschuler, and O. A. Coso. 2003. Activation of JNK by Epac is independent of its activity as a Rap guanine nucleotide exchanger. J. Biol. Chem. 278:33738-33746.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 33738-33746
-
-
Hochbaum, D.1
Tanos, T.2
Ribeiro-Neto, F.3
Altschuler, D.4
Coso, O.A.5
-
34
-
-
21344460965
-
TIPs are tension-responsive proteins involved in myogenic versus adipogenic differentiation
-
Jakkaraju, S., Z. Zhe, D. Pan, R. Choudhury, and L. Schuger. 2005. TIPs are tension-responsive proteins involved in myogenic versus adipogenic differentiation. Dev. Cell 9:39-49.
-
(2005)
Dev. Cell
, vol.9
, pp. 39-49
-
-
Jakkaraju, S.1
Zhe, Z.2
Pan, D.3
Choudhury, R.4
Schuger, L.5
-
35
-
-
0034602375
-
c-Crk, a substrate of the insulin-like growth factor-1 receptor tyrosine kinase, function as an early signal mediator in the adipocyte differentiation process
-
Jin, S., B. Zhai, Z. Qiu, J. Wu, M. D. Lane, and K. Liao. 2000. c-Crk, a substrate of the insulin-like growth factor-1 receptor tyrosine kinase, function as an early signal mediator in the adipocyte differentiation process. J. Biol. Chem. 275:34344-34352.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 34344-34352
-
-
Jin, S.1
Zhai, B.2
Qiu, Z.3
Wu, J.4
Lane, M.D.5
Liao, K.6
-
36
-
-
0035886966
-
cAMP-regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+-induced Ca2+ release in INS-1 pancreatic beta-cells
-
Kang, G., O. G. Chepurny, and G. G. Holz. 2001. cAMP-regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+-induced Ca2+ release in INS-1 pancreatic beta-cells. J. Physiol. (London) 536:375-385.
-
(2001)
J. Physiol. (London)
, vol.536
, pp. 375-385
-
-
Kang, G.1
Chepurny, O.G.2
Holz, G.G.3
-
37
-
-
0037424363
-
2+ release and exocytosis in pancreatic β-cells
-
2+ release and exocytosis in pancreatic β-cells. J. Biol. Chem. 278:8279-8285.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 8279-8285
-
-
Kang, G.1
Joseph, J.W.2
Chepurny, O.G.3
Monaco, M.4
Wheeler, M.B.5
Bos, J.L.6
Schwede, F.7
Genieser, H.G.8
Holz, G.G.9
-
38
-
-
33845764280
-
H-89 potentiates adipogenesis in 3T3-L1 cells by activating insulin signaling independently of protein kinase A
-
Kato, Y., N. Ozaki, T. Yamada, Y. Miura, and Y. Oiso. 2007. H-89 potentiates adipogenesis in 3T3-L1 cells by activating insulin signaling independently of protein kinase A. Life Sci. 80:476-483.
-
(2007)
Life Sci
, vol.80
, pp. 476-483
-
-
Kato, Y.1
Ozaki, N.2
Yamada, T.3
Miura, Y.4
Oiso, Y.5
-
39
-
-
8744232106
-
2+-controlled activation of Ras and extracellular signal-regulated kinases by Gs-coupled receptors
-
2+-controlled activation of Ras and extracellular signal-regulated kinases by Gs-coupled receptors. J. Biol. Chem. 279:46497-46508.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 46497-46508
-
-
Keiper, M.1
Stope, M.B.2
Szatkowski, D.3
Bohm, A.4
Tysack, K.5
vom Dorp, F.6
Saur, O.7
Oude Weernink, P.A.8
Evellin, S.9
Jakobs, K.H.10
Schmidt, M.11
-
40
-
-
0031965333
-
Insulin stimulates cAMP-response element binding protein activity in HepG2 and 3T3-L1 cell lines
-
Klemm, D. J., W. J. Roesler, T. Boras, L. A. Colton, K. Felder, and J. E. B. Reusch. 1998. Insulin stimulates cAMP-response element binding protein activity in HepG2 and 3T3-L1 cell lines. J. Biol. Chem. 273:917-923.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 917-923
-
-
Klemm, D.J.1
Roesler, W.J.2
Boras, T.3
Colton, L.A.4
Felder, K.5
Reusch, J.E.B.6
-
41
-
-
0030040750
-
Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes
-
Lang, P., F. Gesbert, M. Delespine-Carmagnat, R. Stancou, M. Pouchelet, and J. Bertoglio. 1996. Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes. EMBO J. 15:510-519.
-
(1996)
EMBO J
, vol.15
, pp. 510-519
-
-
Lang, P.1
Gesbert, F.2
Delespine-Carmagnat, M.3
Stancou, R.4
Pouchelet, M.5
Bertoglio, J.6
-
42
-
-
0036182854
-
The protein kinase A inhibitor H89 acts on cell morphology by inhibiting Rho kinase
-
Leemhuis, J., S. Boutillier, G. Schmidt, and D. K. Meyer. 2002. The protein kinase A inhibitor H89 acts on cell morphology by inhibiting Rho kinase. J. Pharmacol. Exp. Ther. 300:1000-1007.
-
(2002)
J. Pharmacol. Exp. Ther
, vol.300
, pp. 1000-1007
-
-
Leemhuis, J.1
Boutillier, S.2
Schmidt, G.3
Meyer, D.K.4
-
43
-
-
0038034941
-
Src-CrkII-C3G-dependent activation of Rap1 switches growth hormone-stimulated p44/42 MAP kinase and JNK/SAPK activities
-
Ling, L., T. Zhu, and P. E. Lobie. 2003. Src-CrkII-C3G-dependent activation of Rap1 switches growth hormone-stimulated p44/42 MAP kinase and JNK/SAPK activities. J. Biol. Chem. 278:27301-27311.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 27301-27311
-
-
Ling, L.1
Zhu, T.2
Lobie, P.E.3
-
45
-
-
0029062839
-
Transcriptional regulation of gene expression during adipocyte differentiation
-
MacDougald, O. A., and M. D. Lane. 1995. Transcriptional regulation of gene expression during adipocyte differentiation. Annu. Rev. Biochem. 64:345-373.
-
(1995)
Annu. Rev. Biochem
, vol.64
, pp. 345-373
-
-
MacDougald, O.A.1
Lane, M.D.2
-
46
-
-
0242468739
-
Adipocyte differentiation of 3T3-L1 preadipocytes is dependent on lipoxygenase activity during the initial stages of the differentiation process
-
Madsen, L., R. K. Petersen, M. B. Sørensen, C. Jørgensen, P. Hallenborg, L. Pridal, J. Fleckner, E.-Z. Amri, P. Krieg, G. Furstenberger, R. K. Berge, and K. Kristiansen. 2003. Adipocyte differentiation of 3T3-L1 preadipocytes is dependent on lipoxygenase activity during the initial stages of the differentiation process. Biochem. J. 375:539-549.
-
(2003)
Biochem. J
, vol.375
, pp. 539-549
-
-
Madsen, L.1
Petersen, R.K.2
Sørensen, M.B.3
Jørgensen, C.4
Hallenborg, P.5
Pridal, L.6
Fleckner, J.7
Amri, E.-Z.8
Krieg, P.9
Furstenberger, G.10
Berge, R.K.11
Kristiansen, K.12
-
47
-
-
0035845567
-
Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB
-
Mayr, B. M., G. Canettieri, and M. R. Montminy. 2001. Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB. Proc. Natl. Acad. Sci. USA 98:10936-10941.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10936-10941
-
-
Mayr, B.M.1
Canettieri, G.2
Montminy, M.R.3
-
48
-
-
1842426730
-
Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment
-
McBeath, R., D. M. Pirone, C. M. Nelson, K. Bhadriraju, and C. S. Chen. 2004. Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev. Cell 6:483-495.
-
(2004)
Dev. Cell
, vol.6
, pp. 483-495
-
-
McBeath, R.1
Pirone, D.M.2
Nelson, C.M.3
Bhadriraju, K.4
Chen, C.S.5
-
49
-
-
0037192820
-
Differential signaling of cyclic AMP
-
Mei, F. C., J. Qiao, O. M. Tsygankova, J. L. Meinkoth, L. A. Quilliam, and X. Cheng. 2002. Differential signaling of cyclic AMP. J. Biol. Chem. 277:11497-11504.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 11497-11504
-
-
Mei, F.C.1
Qiao, J.2
Tsygankova, O.M.3
Meinkoth, J.L.4
Quilliam, L.A.5
Cheng, X.6
-
50
-
-
25444492582
-
RhoA and cytoskeletal disruption mediate reduced osteoblastogenesis and enhanced adipogenesis of human mesenchymal stem cells in modeled microgravity
-
Meyers, V. E., M. Zayzafoon, J. T. Douglas, and J. M. McDonald. 2005. RhoA and cytoskeletal disruption mediate reduced osteoblastogenesis and enhanced adipogenesis of human mesenchymal stem cells in modeled microgravity. J. Bone Miner. Res. 20:1858-1866.
-
(2005)
J. Bone Miner. Res
, vol.20
, pp. 1858-1866
-
-
Meyers, V.E.1
Zayzafoon, M.2
Douglas, J.T.3
McDonald, J.M.4
-
51
-
-
35748976234
-
Genetic and pharmacological inhibition of Rho-associated kinase II enhances adipogenesis
-
Noguchi, M., K. Hosoda, J. Fujikura, M. Fujimoto, H. Iwakura, T. Tomita, T. Ishii, N. Arai, M. Hirata, K. Ebihara, H. Masuzaki, H. Itoh, S. Narumiya, and K. Nakao. 2007. Genetic and pharmacological inhibition of Rho-associated kinase II enhances adipogenesis. J. Biol. Chem. 282:29574-29583.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 29574-29583
-
-
Noguchi, M.1
Hosoda, K.2
Fujikura, J.3
Fujimoto, M.4
Iwakura, H.5
Tomita, T.6
Ishii, T.7
Arai, N.8
Hirata, M.9
Ebihara, K.10
Masuzaki, H.11
Itoh, H.12
Narumiya, S.13
Nakao, K.14
-
52
-
-
0033769693
-
cAMP-GEFII is a direct target of cAMP in regulated exocytosis
-
Ozaki, N., T. Shibasaki, Y. Kashima, T. Miki, K. Takahashi, H. Ueno, Y. Sunaga, H. Yano, Y. Matsuura, T. Iwanaga, Y. Takai, and S. Seino. 2000. cAMP-GEFII is a direct target of cAMP in regulated exocytosis. Nat. Cell Biol. 2:805-811.
-
(2000)
Nat. Cell Biol
, vol.2
, pp. 805-811
-
-
Ozaki, N.1
Shibasaki, T.2
Kashima, Y.3
Miki, T.4
Takahashi, K.5
Ueno, H.6
Sunaga, Y.7
Yano, H.8
Matsuura, Y.9
Iwanaga, T.10
Takai, Y.11
Seino, S.12
-
53
-
-
0347269088
-
Arachidonic acid-dependent inhibition of adipocyte differentiation requires PKA activity and is associated with sustained expression of cyclooxygenases
-
Petersen, R. K., C. Jorgensen, A. C. Rustan, L. Froyland, K. Muller-Decker, G. Furstenberger, R. K. Berge, K. Kristiansen, and L. Madsen. 2003. Arachidonic acid-dependent inhibition of adipocyte differentiation requires PKA activity and is associated with sustained expression of cyclooxygenases. J. Lipid Res. 44:2320-2330.
-
(2003)
J. Lipid Res
, vol.44
, pp. 2320-2330
-
-
Petersen, R.K.1
Jorgensen, C.2
Rustan, A.C.3
Froyland, L.4
Muller-Decker, K.5
Furstenberger, G.6
Berge, R.K.7
Kristiansen, K.8
Madsen, L.9
-
54
-
-
0037450725
-
Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the β2-adrenergic receptor
-
Rangarajan, S., J. M. Enserink, H. B. Kuiperij, J. de Rooij, L. S. Price, F. Schwede, and J. L. Bos. 2003. Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the β2-adrenergic receptor. J. Cell Biol. 160:487-493.
-
(2003)
J. Cell Biol
, vol.160
, pp. 487-493
-
-
Rangarajan, S.1
Enserink, J.M.2
Kuiperij, H.B.3
de Rooij, J.4
Price, L.S.5
Schwede, F.6
Bos, J.L.7
-
55
-
-
0034689050
-
The small GTPase, Rap1, mediates CD31-induced integrin adhension
-
Reedquist, K. A., E. Ross, E. A. Koop, R. M. Wolthuis, F. J. Zwartkruis, Y. van Kooyk, M. Salmon, C. D. Buckley, and J. L. Bos. 2000. The small GTPase, Rap1, mediates CD31-induced integrin adhension. J. Cell Biol. 148:1151-1158.
-
(2000)
J. Cell Biol
, vol.148
, pp. 1151-1158
-
-
Reedquist, K.A.1
Ross, E.2
Koop, E.A.3
Wolthuis, R.M.4
Zwartkruis, F.J.5
van Kooyk, Y.6
Salmon, M.7
Buckley, C.D.8
Bos, J.L.9
-
56
-
-
0033982177
-
CREB activation induces adipogenesis in 3T3-L1 cells
-
Reusch, J. E. B., L. A. Colton, and D. J. Klemm. 2000. CREB activation induces adipogenesis in 3T3-L1 cells. Mol. Cell. Biol. 20:1008-1020.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 1008-1020
-
-
Reusch, J.E.B.1
Colton, L.A.2
Klemm, D.J.3
-
57
-
-
0037059834
-
Inhibition of cAMP-response element-binding protein activity decreases protein kinase B/Akt expression in 3T3-L1 adipocytes and induces apoptosis
-
Reusch, J. E. B., and D. J. Klemm. 2002. Inhibition of cAMP-response element-binding protein activity decreases protein kinase B/Akt expression in 3T3-L1 adipocytes and induces apoptosis. J. Biol. Chem. 277:1426-1432.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 1426-1432
-
-
Reusch, J.E.B.1
Klemm, D.J.2
-
58
-
-
33845325476
-
Adipocyte differentiation from the inside out
-
Rosen, E. D., and O. A. MacDougald. 2006. Adipocyte differentiation from the inside out. Nat. Rev. Mol. Cell Biol. 7:885-896.
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
, pp. 885-896
-
-
Rosen, E.D.1
MacDougald, O.A.2
-
59
-
-
0025160568
-
Adipose conversion of 3T3-L1 cells in a serum-free culture system depends on epidermal growth factor, insulin-like growth factor I, corticosterone, and cyclic AMP
-
Schmidt, W., G. Poll-Jordan, and G. Loffler. 1990. Adipose conversion of 3T3-L1 cells in a serum-free culture system depends on epidermal growth factor, insulin-like growth factor I, corticosterone, and cyclic AMP. J. Biol. Chem. 265:15489-15495.
-
(1990)
J. Biol. Chem
, vol.265
, pp. 15489-15495
-
-
Schmidt, W.1
Poll-Jordan, G.2
Loffler, G.3
-
60
-
-
33845194359
-
A novel cyclic AMP-dependent Epac-Rit signaling pathway contributes to PACAP38-mediated neuronal differentiation
-
Shi, G.-X., H. Rehmann, and D. A. Andres. 2006. A novel cyclic AMP-dependent Epac-Rit signaling pathway contributes to PACAP38-mediated neuronal differentiation. Mol. Cell. Biol. 26:9136-9147.
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 9136-9147
-
-
Shi, G.-X.1
Rehmann, H.2
Andres, D.A.3
-
61
-
-
0023919926
-
Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes
-
Smith, P. J., L. S. Wise, R. Berkowitz, C. Wan, and C. S. Rubin. 1988. Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes. J. Biol. Chem. 263:9402-9408.
-
(1988)
J. Biol. Chem
, vol.263
, pp. 9402-9408
-
-
Smith, P.J.1
Wise, L.S.2
Berkowitz, R.3
Wan, C.4
Rubin, C.S.5
-
62
-
-
18444411005
-
Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development
-
Sordella, R., M. Classon, K. Hu, SF. Matheson, M. Brouns, B. Fine, L. Zhang, S. Takase, Y. Yamada, and J. Settleman. 2002. Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development. Dev. Cell 2:553-565.
-
(2002)
Dev. Cell
, vol.2
, pp. 553-565
-
-
Sordella, R.1
Classon, M.2
Hu, K.3
Matheson, S.F.4
Brouns, M.5
Fine, B.6
Zhang, L.7
Takase, S.8
Yamada, Y.9
Settleman, J.10
-
63
-
-
0037453716
-
Modulation of Rho GTPase signaling regulates a switch between adipogenesis and myogenesis
-
Sordella, R., W. Jiang, G. C. Chen, M. Curto, and J. Settleman. 2003. Modulation of Rho GTPase signaling regulates a switch between adipogenesis and myogenesis. Cell 113:147-158.
-
(2003)
Cell
, vol.113
, pp. 147-158
-
-
Sordella, R.1
Jiang, W.2
Chen, G.C.3
Curto, M.4
Settleman, J.5
-
64
-
-
0033059674
-
Repressive effect of Sp1 on the C/EBPα gene promoter: Role in adipocyte differentiation
-
Tang, Q.-Q., M.-S. Jiang, and M. D. Lane. 1999. Repressive effect of Sp1 on the C/EBPα gene promoter: role in adipocyte differentiation. Mol. Cell. Biol. 19:4855-4865.
-
(1999)
Mol. Cell. Biol
, vol.19
, pp. 4855-4865
-
-
Tang, Q.-Q.1
Jiang, M.-S.2
Lane, M.D.3
-
65
-
-
0033200389
-
Activation and centromeric localization of CCAAT/enhancer-binding proteins during the mitotic clonal expansion of adipocyte differentiation
-
Tang, Q. Q., and M. D. Lane. 1999. Activation and centromeric localization of CCAAT/enhancer-binding proteins during the mitotic clonal expansion of adipocyte differentiation. Genes Dev. 13:2231-2241.
-
(1999)
Genes Dev
, vol.13
, pp. 2231-2241
-
-
Tang, Q.Q.1
Lane, M.D.2
-
66
-
-
1942456595
-
Sequential gene promoter interactions by C/EBPβ, C/EBPα, and PPARγ during adipogenesis
-
Tang, Q. Q., J. W. Zhang, and M. D. Lane. 2004. Sequential gene promoter interactions by C/EBPβ, C/EBPα, and PPARγ during adipogenesis. Biochem. Biophys. Res. Commun. 318:213-218.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.318
, pp. 213-218
-
-
Tang, Q.Q.1
Zhang, J.W.2
Lane, M.D.3
-
67
-
-
4143099405
-
Regulated production of a peroxisome proliferator-activated receptor-γ ligand during an early phase of adipocyte differentiation in 3T3-L1 adipocytes
-
Tzameli, I., H. Fang, M. Ollero, H. Shi, J. K. Hamm, P. Kievit, A. N. Hollenberg, and J. S. Flier. 2004. Regulated production of a peroxisome proliferator-activated receptor-γ ligand during an early phase of adipocyte differentiation in 3T3-L1 adipocytes. J. Biol. Chem. 279:36093-36102.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 36093-36102
-
-
Tzameli, I.1
Fang, H.2
Ollero, M.3
Shi, H.4
Hamm, J.K.5
Kievit, P.6
Hollenberg, A.N.7
Flier, J.S.8
-
68
-
-
0038190982
-
Cdc42 is a Rho GTPase family member that can mediate insulin signaling to glucose transport in 3T3-L1 adipocytes
-
Usui, I., T. Imamura, J. Huang, H. Satoh, and J. M. Olefsky. 2003. Cdc42 is a Rho GTPase family member that can mediate insulin signaling to glucose transport in 3T3-L1 adipocytes. J. Biol. Chem. 278:13765-13774.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 13765-13774
-
-
Usui, I.1
Imamura, T.2
Huang, J.3
Satoh, H.4
Olefsky, J.M.5
-
69
-
-
33751256003
-
-
Wildenberg, G. A., M. R. Dohn, R. H. Carnahan, M. A. Davis, N. A. Lobdell, J. Settlemen, and A. B. Reynolds. 2007. p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho. Cell 127:1027-1039.
-
Wildenberg, G. A., M. R. Dohn, R. H. Carnahan, M. A. Davis, N. A. Lobdell, J. Settlemen, and A. B. Reynolds. 2007. p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho. Cell 127:1027-1039.
-
-
-
-
70
-
-
0028878375
-
Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins
-
Yeh, W., Z. Cao, M. Classon, and S. McKnight. 1995. Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins. Genes Dev. 9:168-181.
-
(1995)
Genes Dev
, vol.9
, pp. 168-181
-
-
Yeh, W.1
Cao, Z.2
Classon, M.3
McKnight, S.4
-
71
-
-
25644446102
-
-
Zhang, J., C. J. Hupfeld, S. S. Taylor, J. M. Olefsky, and R. Y. Tsien. 2005. Insulin disrupts β-adrenergic signalling to protein kinase A in adipocytes. Nature 437:569-573. (Letter.)
-
Zhang, J., C. J. Hupfeld, S. S. Taylor, J. M. Olefsky, and R. Y. Tsien. 2005. Insulin disrupts β-adrenergic signalling to protein kinase A in adipocytes. Nature 437:569-573. (Letter.)
-
-
-
-
72
-
-
1042289760
-
Role of CREB in transcriptional regulation of CCAAT/enhancer-binding protein beta gene during adipogenesis
-
Zhang, J.-W., D. J. Klemm, C. Vinson, and M. D. Lane. 2004. Role of CREB in transcriptional regulation of CCAAT/enhancer-binding protein beta gene during adipogenesis. J. Biol. Chem. 279:4471-4478.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 4471-4478
-
-
Zhang, J.-W.1
Klemm, D.J.2
Vinson, C.3
Lane, M.D.4
-
73
-
-
33845460303
-
Novel mechanisms of the regulation of protein kinase B in adipocytes; implications for protein kinase A, Epac, phosphodiesterases 3 and 4
-
Zmuda-Trzebiatowska, E., V. Manganiello, and E. Degerman. 2007. Novel mechanisms of the regulation of protein kinase B in adipocytes; implications for protein kinase A, Epac, phosphodiesterases 3 and 4. Cell. Signal. 19:81-86.
-
(2007)
Cell. Signal
, vol.19
, pp. 81-86
-
-
Zmuda-Trzebiatowska, E.1
Manganiello, V.2
Degerman, E.3
|