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Volumn 148, Issue 10, 2007, Pages 4612-4622

Cyclic adenosine 3′,5′-monophosphate (cAMP)-dependent protein kinases, but not exchange proteins directly activated by cAMP (Epac), mediate thyrotropin/cAMP-dependent regulation of thyroid cells

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; COMPLEMENTARY DNA; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HYDROGEN PEROXIDE; LIOTHYRONINE; MESSENGER RNA; RAP PROTEIN; S6 KINASE; THYROID HORMONE; THYROTROPIN; THYROXINE;

EID: 34748905609     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2007-0540     Document Type: Article
Times cited : (32)

References (80)
  • 1
    • 0026661582 scopus 로고
    • Physiological and pathological regulation of thyroid cell proliferation and differentiation by thyrotropin and other factors
    • Dumont JE, Lamy F, Roger P, Maenhaut C 1992 Physiological and pathological regulation of thyroid cell proliferation and differentiation by thyrotropin and other factors. Physiol Rev 72:667-697
    • (1992) Physiol Rev , vol.72 , pp. 667-697
    • Dumont, J.E.1    Lamy, F.2    Roger, P.3    Maenhaut, C.4
  • 2
    • 34748908046 scopus 로고    scopus 로고
    • Dumont JE, Maenhaut C, Christophe D, Vassart G, Roger PP 2005 Thyroid regulatory factors. In: DeGroot LJ, Jameson JL, eds. Endocrinology. 2, part 10. Philadelphia: Elsevier Saunders; 1837-1860
    • Dumont JE, Maenhaut C, Christophe D, Vassart G, Roger PP 2005 Thyroid regulatory factors. In: DeGroot LJ, Jameson JL, eds. Endocrinology. Vol 2, part 10. Philadelphia: Elsevier Saunders; 1837-1860
  • 4
    • 0031453935 scopus 로고    scopus 로고
    • The dog thyroid primary culture system: A model of the regulation of function, growth and differentiation expression by cAMP and other well-defined signaling cascades
    • Roger PP, Christophe D, Dumont JE, Pirson I 1997 The dog thyroid primary culture system: a model of the regulation of function, growth and differentiation expression by cAMP and other well-defined signaling cascades. Eur J Endocrinol 137:579-598
    • (1997) Eur J Endocrinol , vol.137 , pp. 579-598
    • Roger, P.P.1    Christophe, D.2    Dumont, J.E.3    Pirson, I.4
  • 5
    • 0034793849 scopus 로고    scopus 로고
    • Regulation of thyroid cell proliferation by thyrotropin and other factors: A critical evaluation of in vitro models
    • Kimura T, Van Keymeulen A, Golstein J, Fusco A, Dumont JE, Roger PP 2001 Regulation of thyroid cell proliferation by thyrotropin and other factors: a critical evaluation of in vitro models. Endocr Rev 22:631-656
    • (2001) Endocr Rev , vol.22 , pp. 631-656
    • Kimura, T.1    Van Keymeulen, A.2    Golstein, J.3    Fusco, A.4    Dumont, J.E.5    Roger, P.P.6
  • 6
    • 27844543731 scopus 로고    scopus 로고
    • Differential involvement of the actin cytoskeleton in differentiation and mitogenesis of thyroid cells: Inactivation of Rho proteins contributes to cyclic adenosine monophosphate-dependent gene expression but prevents mitogenesis
    • Fortemaison N, Blancquaert S, Dumont JE, Maenhaut C, Aktories K, Roger PP, Dremier S 2005 Differential involvement of the actin cytoskeleton in differentiation and mitogenesis of thyroid cells: inactivation of Rho proteins contributes to cyclic adenosine monophosphate-dependent gene expression but prevents mitogenesis. Endocrinology 146:5485-5495
    • (2005) Endocrinology , vol.146 , pp. 5485-5495
    • Fortemaison, N.1    Blancquaert, S.2    Dumont, J.E.3    Maenhaut, C.4    Aktories, K.5    Roger, P.P.6    Dremier, S.7
  • 7
    • 0028276647 scopus 로고
    • Characterization and identification as cofilin and destrin of two thyrotropin- and phorbol ester-regulated phosphoproteins in thyroid cells
    • Saito T, Lamy F, Roger PP, Lecocq R, Dumont JE 1994 Characterization and identification as cofilin and destrin of two thyrotropin- and phorbol ester-regulated phosphoproteins in thyroid cells. Exp Cell Res 212:49-61
    • (1994) Exp Cell Res , vol.212 , pp. 49-61
    • Saito, T.1    Lamy, F.2    Roger, P.P.3    Lecocq, R.4    Dumont, J.E.5
  • 8
    • 0024567111 scopus 로고
    • Actin stress fiber disruption and tropomyosin isoform switching in normal thyroid epithelial cells stimulated by thyrotropin and phorbol esters
    • Roger PP, Rickaert F, Lamy F, Authelet M, Dumont JE 1989 Actin stress fiber disruption and tropomyosin isoform switching in normal thyroid epithelial cells stimulated by thyrotropin and phorbol esters. Exp Cell Res 182:1-13
    • (1989) Exp Cell Res , vol.182 , pp. 1-13
    • Roger, P.P.1    Rickaert, F.2    Lamy, F.3    Authelet, M.4    Dumont, J.E.5
  • 11
    • 0027463240 scopus 로고
    • Phosphorylation of mitogen-activated protein kinases is involved in the epidermal growth factor and phorbol ester, but not in the thyrotropin/cAMP, thyroid mitogenic pathway
    • Lamy F, Wilkin F, Baptist M, Posada J, Roger PP, Dumont JE 1993 Phosphorylation of mitogen-activated protein kinases is involved in the epidermal growth factor and phorbol ester, but not in the thyrotropin/cAMP, thyroid mitogenic pathway. J Biol Chem 268:8398-8401
    • (1993) J Biol Chem , vol.268 , pp. 8398-8401
    • Lamy, F.1    Wilkin, F.2    Baptist, M.3    Posada, J.4    Roger, P.P.5    Dumont, J.E.6
  • 12
    • 0037389888 scopus 로고    scopus 로고
    • Role of the different mitogen-activated protein kinase subfamilies in the stimulation of dog and human thyroid epithelial cell proliferation by cyclic adenosine 5′-monophosphate and growth factors
    • Vandeput F, Perpete S, Coulonval K, Lamy F, Dumont JE 2003 Role of the different mitogen-activated protein kinase subfamilies in the stimulation of dog and human thyroid epithelial cell proliferation by cyclic adenosine 5′-monophosphate and growth factors. Endocrinology 144:1341-1349
    • (2003) Endocrinology , vol.144 , pp. 1341-1349
    • Vandeput, F.1    Perpete, S.2    Coulonval, K.3    Lamy, F.4    Dumont, J.E.5
  • 13
    • 0034214102 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase, protein kinase B and ribosomal S6 kinases in the stimulation of thyroid epithelial cell proliferation by cAMP and growth factors in the presence of insulin
    • Coulonval K, Vandeput F, Stein R, Kozma S, Lamy F, Dumont JE 2000 Phosphatidylinositol 3-kinase, protein kinase B and ribosomal S6 kinases in the stimulation of thyroid epithelial cell proliferation by cAMP and growth factors in the presence of insulin. Biochem J 348:351-358
    • (2000) Biochem J , vol.348 , pp. 351-358
    • Coulonval, K.1    Vandeput, F.2    Stein, R.3    Kozma, S.4    Lamy, F.5    Dumont, J.E.6
  • 15
    • 0025330489 scopus 로고
    • cAMP-dependent protein kinase: Framework for a diverse family of regulatory enzymes
    • Taylor SS, Buechler JA, Yonemoto W 1990 cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes. Annu Rev Biochem 59:971-1005
    • (1990) Annu Rev Biochem , vol.59 , pp. 971-1005
    • Taylor, S.S.1    Buechler, J.A.2    Yonemoto, W.3
  • 16
    • 0027265948 scopus 로고
    • The genetic subtypes of cAMP-dependent protein kinase - functionally different or redundant?
    • Doskeland SO, Maronde E, Gjertsen BT 1993 The genetic subtypes of cAMP-dependent protein kinase - functionally different or redundant? Biochim Biophys Acta 1178:249-258
    • (1993) Biochim Biophys Acta , vol.1178 , pp. 249-258
    • Doskeland, S.O.1    Maronde, E.2    Gjertsen, B.T.3
  • 19
    • 25444520038 scopus 로고    scopus 로고
    • PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis
    • Seino S, Shibasaki T 2005 PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis. Physiol Rev 85:1303-1342
    • (2005) Physiol Rev , vol.85 , pp. 1303-1342
    • Seino, S.1    Shibasaki, T.2
  • 20
    • 33751241720 scopus 로고    scopus 로고
    • Epac proteins: Multi-purpose cAMP targets
    • Bos JL 2006 Epac proteins: multi-purpose cAMP targets. Trends Biochem Sci 31:680-686
    • (2006) Trends Biochem Sci , vol.31 , pp. 680-686
    • Bos, J.L.1
  • 22
    • 33746469525 scopus 로고    scopus 로고
    • Epac1 and cAMP-dependent protein kinase holoenzyme have similar cAMP affinity, but their cAMP domains have distinct structural features and cyclic nucleotide recognition
    • Dao KK, Teigen K, Kopperud R, Hodneland E, Schwede F, Christensen AE, Martinez A, Doskeland SO 2006 Epac1 and cAMP-dependent protein kinase holoenzyme have similar cAMP affinity, but their cAMP domains have distinct structural features and cyclic nucleotide recognition. J Biol Chem 281:21500-21511
    • (2006) J Biol Chem , vol.281 , pp. 21500-21511
    • Dao, K.K.1    Teigen, K.2    Kopperud, R.3    Hodneland, E.4    Schwede, F.5    Christensen, A.E.6    Martinez, A.7    Doskeland, S.O.8
  • 23
    • 0141780889 scopus 로고    scopus 로고
    • Activation of JNK by Epac is independent of its activity as a Rap guanine nucleotide exchanger
    • Hochbaum D, Tanos T, Ribeiro-Neto F, Altschuler D, Coso OA 2003 Activation of JNK by Epac is independent of its activity as a Rap guanine nucleotide exchanger. J Biol Chem 278:33738-33746
    • (2003) J Biol Chem , vol.278 , pp. 33738-33746
    • Hochbaum, D.1    Tanos, T.2    Ribeiro-Neto, F.3    Altschuler, D.4    Coso, O.A.5
  • 25
    • 0030857981 scopus 로고    scopus 로고
    • Activation of cyclic AMP-dependent kinase is required but may not be sufficient to mimic cyclic AMP-dependent DNA synthesis and thyroglobulin expression in dog thyroid cells
    • Dremier S, Pohl V, Poteet-Smith C, Roger PP, Corbin J, Doskeland SO, Dumont JE, Maenhaut C 1997 Activation of cyclic AMP-dependent kinase is required but may not be sufficient to mimic cyclic AMP-dependent DNA synthesis and thyroglobulin expression in dog thyroid cells. Mol Cell Biol 17:6717-6726
    • (1997) Mol Cell Biol , vol.17 , pp. 6717-6726
    • Dremier, S.1    Pohl, V.2    Poteet-Smith, C.3    Roger, P.P.4    Corbin, J.5    Doskeland, S.O.6    Dumont, J.E.7    Maenhaut, C.8
  • 26
    • 0033049567 scopus 로고    scopus 로고
    • The paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription
    • Ohno M, Zannini M, Levy O, Carrasco N, Di Lauro R 1999 The paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription. Mol Cell Biol 19:2051-2060
    • (1999) Mol Cell Biol , vol.19 , pp. 2051-2060
    • Ohno, M.1    Zannini, M.2    Levy, O.3    Carrasco, N.4    Di Lauro, R.5
  • 29
    • 0141532168 scopus 로고    scopus 로고
    • Ligand-mediated activation of the cAMP-responsive guanine nucleotide exchange factor Epac
    • Rehmann H, Schwede F, Doskeland SO, Wittinghofer A, Bos JL 2003 Ligand-mediated activation of the cAMP-responsive guanine nucleotide exchange factor Epac. J Biol Chem 278:38548-38556
    • (2003) J Biol Chem , vol.278 , pp. 38548-38556
    • Rehmann, H.1    Schwede, F.2    Doskeland, S.O.3    Wittinghofer, A.4    Bos, J.L.5
  • 31
    • 26244462666 scopus 로고    scopus 로고
    • Enhanced functional gap junction neoformation by protein kinase A-dependent and Epac-dependent signals downstream of cAMP in cardiac myocytes
    • Somekawa S, Fukuhara S, Nakaoka Y, Fujita H, Saito Y, Mochizuki N 2005 Enhanced functional gap junction neoformation by protein kinase A-dependent and Epac-dependent signals downstream of cAMP in cardiac myocytes. Circ Res 97:655-662
    • (2005) Circ Res , vol.97 , pp. 655-662
    • Somekawa, S.1    Fukuhara, S.2    Nakaoka, Y.3    Fujita, H.4    Saito, Y.5    Mochizuki, N.6
  • 33
    • 33744899583 scopus 로고    scopus 로고
    • The cyclic AMP-Epac1-Rap1 pathway is dissociated from regulation of effector functions in monocytes but acquires immunoregulatory function in mature macrophages
    • Bryn T, Mahic M, Enserink JM, Schwede F, Aandahl EM, Tasken K 2006 The cyclic AMP-Epac1-Rap1 pathway is dissociated from regulation of effector functions in monocytes but acquires immunoregulatory function in mature macrophages. J Immunol 176:7361-7370
    • (2006) J Immunol , vol.176 , pp. 7361-7370
    • Bryn, T.1    Mahic, M.2    Enserink, J.M.3    Schwede, F.4    Aandahl, E.M.5    Tasken, K.6
  • 34
    • 0029946456 scopus 로고    scopus 로고
    • Identification and characterization of novel genes modulated in the thyroid of dogs treated with methimazole and propylthiouracil
    • Wilkin F, Savonet V, Radulescu A, Petermans J, Dumont JE, Maenhaut C 1996 Identification and characterization of novel genes modulated in the thyroid of dogs treated with methimazole and propylthiouracil. J Biol Chem 271:28451-28457
    • (1996) J Biol Chem , vol.271 , pp. 28451-28457
    • Wilkin, F.1    Savonet, V.2    Radulescu, A.3    Petermans, J.4    Dumont, J.E.5    Maenhaut, C.6
  • 35
    • 0023112111 scopus 로고
    • Induction of DNA synthesis in dog thyrocytes in primary culture: Synergistic effects of thyrotropin and cyclic AMP with epidermal growth factor and insulin
    • Roger PP, Servais P, Dumont JE 1987 Induction of DNA synthesis in dog thyrocytes in primary culture: synergistic effects of thyrotropin and cyclic AMP with epidermal growth factor and insulin. J Cell Physiol 130:58-67
    • (1987) J Cell Physiol , vol.130 , pp. 58-67
    • Roger, P.P.1    Servais, P.2    Dumont, J.E.3
  • 36
    • 0023938338 scopus 로고
    • Mitogenic effects of thyrotropin and adenosine 3′,5′-monophosphate in differentiated normal human thyroid cells in vitro
    • Roger P, Taton M, Van Sande J, Dumont JE 1988 Mitogenic effects of thyrotropin and adenosine 3′,5′-monophosphate in differentiated normal human thyroid cells in vitro. J Clin Endocrinol Metab 66:1158-1165
    • (1988) J Clin Endocrinol Metab , vol.66 , pp. 1158-1165
    • Roger, P.1    Taton, M.2    Van Sande, J.3    Dumont, J.E.4
  • 37
    • 0032974382 scopus 로고    scopus 로고
    • Insulin and TSH promote growth in size of PC Cl3 rat thyroid cells, possibly via a pathway different from DNA synthesis: Comparison with FRTL-5 cells
    • Kimura T, Dumont JE, Fusco A, Golstein J 1999 Insulin and TSH promote growth in size of PC Cl3 rat thyroid cells, possibly via a pathway different from DNA synthesis: comparison with FRTL-5 cells. Eur J Endocrinol 140:94-103
    • (1999) Eur J Endocrinol , vol.140 , pp. 94-103
    • Kimura, T.1    Dumont, J.E.2    Fusco, A.3    Golstein, J.4
  • 38
    • 0035091805 scopus 로고    scopus 로고
    • Respective roles of carbamylcholine and cyclic AMP in their synergistic regulation of cell cycle in thyroid primary cultures
    • Van Keymeulen A, Deleu S, Bartek J, Dumont JE, Roger PP 2001 Respective roles of carbamylcholine and cyclic AMP in their synergistic regulation of cell cycle in thyroid primary cultures. Endocrinology 142:1251-1259
    • (2001) Endocrinology , vol.142 , pp. 1251-1259
    • Van Keymeulen, A.1    Deleu, S.2    Bartek, J.3    Dumont, J.E.4    Roger, P.P.5
  • 40
    • 0020677312 scopus 로고
    • Thyrotrophin and the differential expression of proliferation and differentiation in dog thyroid cells in primary culture
    • Roger PP, Dumont JE 1983 Thyrotrophin and the differential expression of proliferation and differentiation in dog thyroid cells in primary culture. J Endocrinol 96:241-249
    • (1983) J Endocrinol , vol.96 , pp. 241-249
    • Roger, P.P.1    Dumont, J.E.2
  • 41
    • 0028821542 scopus 로고
    • Tonic modulation of dog thyrocyte H2O2 generation and I- uptake by thyrotropin through the cyclic adenosine 3′,5′-monophosphate cascade
    • Raspe E, Dumont JE 1995 Tonic modulation of dog thyrocyte H2O2 generation and I- uptake by thyrotropin through the cyclic adenosine 3′,5′-monophosphate cascade. Endocrinology 136:965-973
    • (1995) Endocrinology , vol.136 , pp. 965-973
    • Raspe, E.1    Dumont, J.E.2
  • 42
    • 0022398707 scopus 로고
    • Antagonistic effects of thyrotropin and epidermal growth factor on thyroglobulin mRNA level in cultured thyroid cells
    • Roger PP, Van Heuverswyn B, Lambert C, Reuse S, Vassart G, Dumont JE 1985 Antagonistic effects of thyrotropin and epidermal growth factor on thyroglobulin mRNA level in cultured thyroid cells. Eur J Biochem 152:239-245
    • (1985) Eur J Biochem , vol.152 , pp. 239-245
    • Roger, P.P.1    Van Heuverswyn, B.2    Lambert, C.3    Reuse, S.4    Vassart, G.5    Dumont, J.E.6
  • 43
    • 0028334583 scopus 로고
    • Mitogenic, dedifferentiating, and scattering effects of hepatocyte growth factor on dog thyroid cells
    • Dremier S, Taton M, Coulonval K, Nakamura T, Matsumoto K, Dumont JE 1994 Mitogenic, dedifferentiating, and scattering effects of hepatocyte growth factor on dog thyroid cells. Endocrinology 135:135-140
    • (1994) Endocrinology , vol.135 , pp. 135-140
    • Dremier, S.1    Taton, M.2    Coulonval, K.3    Nakamura, T.4    Matsumoto, K.5    Dumont, J.E.6
  • 44
    • 0037135592 scopus 로고    scopus 로고
    • Cell cycle-dependent subcellular localization of exchange factor directly activated by cAMP
    • Qiao J, Mei FC, Popov VL, Vergara LA, Cheng X 2002 Cell cycle-dependent subcellular localization of exchange factor directly activated by cAMP. J Biol Chem 277:26581-26586
    • (2002) J Biol Chem , vol.277 , pp. 26581-26586
    • Qiao, J.1    Mei, F.C.2    Popov, V.L.3    Vergara, L.A.4    Cheng, X.5
  • 45
    • 33646366678 scopus 로고    scopus 로고
    • The RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membrane
    • Li Y, Asuri S, Rebhun JF, Castro AF, Paranavitana NC, Quilliam LA 2006 The RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membrane. J Biol Chem 281:2506-2514
    • (2006) J Biol Chem , vol.281 , pp. 2506-2514
    • Li, Y.1    Asuri, S.2    Rebhun, J.F.3    Castro, A.F.4    Paranavitana, N.C.5    Quilliam, L.A.6
  • 46
    • 33644765206 scopus 로고    scopus 로고
    • Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation
    • Wang Z, Dillon TJ, Pokala V, Mishra S, Labudda K, Hunter B, Stork PJ 2006 Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation. Mol Cell Biol 26:2130-2145
    • (2006) Mol Cell Biol , vol.26 , pp. 2130-2145
    • Wang, Z.1    Dillon, T.J.2    Pokala, V.3    Mishra, S.4    Labudda, K.5    Hunter, B.6    Stork, P.J.7
  • 47
    • 0036607064 scopus 로고    scopus 로고
    • Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation
    • Stork PJ, Schmitt JM 2002 Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation. Trends Cell Biol 12:258-266
    • (2002) Trends Cell Biol , vol.12 , pp. 258-266
    • Stork, P.J.1    Schmitt, J.M.2
  • 48
    • 22544463087 scopus 로고    scopus 로고
    • Integrating signals between cAMP and the RAS/RAF/MEK/ERK signalling pathways
    • Dumaz N, Marais R 2005 Integrating signals between cAMP and the RAS/RAF/MEK/ERK signalling pathways. FEBS J 272:3491-3504
    • (2005) FEBS J , vol.272 , pp. 3491-3504
    • Dumaz, N.1    Marais, R.2
  • 49
    • 0035016611 scopus 로고    scopus 로고
    • Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A
    • Tsygankova OM, Saavedra A, Rebhun JF, Quilliam LA, Meinkoth JL 2001 Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A. Mol Cell Biol 21:1921-1929
    • (2001) Mol Cell Biol , vol.21 , pp. 1921-1929
    • Tsygankova, O.M.1    Saavedra, A.2    Rebhun, J.F.3    Quilliam, L.A.4    Meinkoth, J.L.5
  • 50
    • 0037031872 scopus 로고    scopus 로고
    • Lou L, Urbani J, Ribeiro-Neto F, Altschuler DL 2002 cAMP inhibition of Akt is mediated by activated and phosphorylated Rap1b. J Biol Chem 277:32799-32806
    • Lou L, Urbani J, Ribeiro-Neto F, Altschuler DL 2002 cAMP inhibition of Akt is mediated by activated and phosphorylated Rap1b. J Biol Chem 277:32799-32806
  • 51
    • 0037117596 scopus 로고    scopus 로고
    • On the mitogenic properties of Rap1b: CAMP-induced G(1)/S entry requires activated and phosphorylated Rap1b
    • Ribeiro-Neto F, Urbani J, Lemee N, Lou L, Altschuler DL 2002 On the mitogenic properties of Rap1b: cAMP-induced G(1)/S entry requires activated and phosphorylated Rap1b. Proc Natl Acad Sci USA 99:5418-5423
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 5418-5423
    • Ribeiro-Neto, F.1    Urbani, J.2    Lemee, N.3    Lou, L.4    Altschuler, D.L.5
  • 52
    • 0034753081 scopus 로고    scopus 로고
    • Thyrotropin activates mitogen-activated protein kinase pathway in FRTL-5 by a cAMP-dependent protein kinase A-independent mechanism
    • Iacovelli L, Capobianco L, Salvatore L, Sallese M, D'Ancona GM, De Blasi A 2001 Thyrotropin activates mitogen-activated protein kinase pathway in FRTL-5 by a cAMP-dependent protein kinase A-independent mechanism. Mol Pharmacol 60:924-933
    • (2001) Mol Pharmacol , vol.60 , pp. 924-933
    • Iacovelli, L.1    Capobianco, L.2    Salvatore, L.3    Sallese, M.4    D'Ancona, G.M.5    De Blasi, A.6
  • 53
    • 0037151052 scopus 로고    scopus 로고
    • New signaling pathway for parathyroid hormone and cyclic AMP action on extracellular-regulated kinase and cell proliferation in bone cells. Checkpoint of modulation by cyclic AMP
    • Fujita T, Meguro T, Fukuyama R, Nakamuta H, Koida M 2002 New signaling pathway for parathyroid hormone and cyclic AMP action on extracellular-regulated kinase and cell proliferation in bone cells. Checkpoint of modulation by cyclic AMP. J Biol Chem 277:22191-22200
    • (2002) J Biol Chem , vol.277 , pp. 22191-22200
    • Fujita, T.1    Meguro, T.2    Fukuyama, R.3    Nakamuta, H.4    Koida, M.5
  • 54
    • 0037166283 scopus 로고    scopus 로고
    • Protein kinase A-independent activation of ERK and H,K-ATPase by cAMP in native kidney cells: Role of Epac I
    • Laroche-Joubert N, Marsy S, Michelet S, Imbert-Teboul M, Doucet A 2002 Protein kinase A-independent activation of ERK and H,K-ATPase by cAMP in native kidney cells: role of Epac I. J Biol Chem 277:18598-18604
    • (2002) J Biol Chem , vol.277 , pp. 18598-18604
    • Laroche-Joubert, N.1    Marsy, S.2    Michelet, S.3    Imbert-Teboul, M.4    Doucet, A.5
  • 55
    • 33746076698 scopus 로고    scopus 로고
    • Role of the exchange protein directly activated by cyclic adenosine 5′-monophosphate (Epac) pathway in regulating proglucagon gene expression in intestinal endocrine L cells
    • Lotfi S, Li Z, Sun J, Zuo Y, Lam PP, Kang Y, Rahimi M, Islam D, Wang P, Gaisano HY, Jin T 2006 Role of the exchange protein directly activated by cyclic adenosine 5′-monophosphate (Epac) pathway in regulating proglucagon gene expression in intestinal endocrine L cells. Endocrinology 147:3727-3736
    • (2006) Endocrinology , vol.147 , pp. 3727-3736
    • Lotfi, S.1    Li, Z.2    Sun, J.3    Zuo, Y.4    Lam, P.P.5    Kang, Y.6    Rahimi, M.7    Islam, D.8    Wang, P.9    Gaisano, H.Y.10    Jin, T.11
  • 56
    • 0028791019 scopus 로고
    • Intercellular heterogeneity of early mitogenic events: CAMP generalizes the EGF effect on c-Fos protein appearance but not on MAP kinase phosphorylation and nuclear translocation in dog thyroid epithelial cells
    • Baptist M, Dumont JE, Roger PP 1995 Intercellular heterogeneity of early mitogenic events: cAMP generalizes the EGF effect on c-Fos protein appearance but not on MAP kinase phosphorylation and nuclear translocation in dog thyroid epithelial cells. Exp Cell Res 221:160-171
    • (1995) Exp Cell Res , vol.221 , pp. 160-171
    • Baptist, M.1    Dumont, J.E.2    Roger, P.P.3
  • 57
    • 0023948775 scopus 로고
    • Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase triggers acute morphological changes in thyroid epithelial cells
    • Roger PP, Rickaert F, Huez G, Authelet M, Hofmann F, Dumont JE 1988 Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase triggers acute morphological changes in thyroid epithelial cells. FEBS Lett 232:409-413
    • (1988) FEBS Lett , vol.232 , pp. 409-413
    • Roger, P.P.1    Rickaert, F.2    Huez, G.3    Authelet, M.4    Hofmann, F.5    Dumont, J.E.6
  • 58
    • 15044359236 scopus 로고    scopus 로고
    • Linking Rap to cell adhesion
    • Bos JL 2005 Linking Rap to cell adhesion. Curr Opin Cell Biol 17:123-128
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 123-128
    • Bos, J.L.1
  • 59
    • 0020957921 scopus 로고
    • Stimulation by thyrotropin and cyclic AMP of the proliferation of quiescent canine thyroid cells cultured in a defined medium containing insulin
    • Roger PP, Servais P, Dumont JE 1983 Stimulation by thyrotropin and cyclic AMP of the proliferation of quiescent canine thyroid cells cultured in a defined medium containing insulin. FEBS Lett 157:323-329
    • (1983) FEBS Lett , vol.157 , pp. 323-329
    • Roger, P.P.1    Servais, P.2    Dumont, J.E.3
  • 60
  • 61
    • 0038036033 scopus 로고    scopus 로고
    • Cyclic AMP-dependent phosphorylation of cyclin D3-bound CDK4 determines the passage through the cell cycle restriction point in thyroid epithelial cells
    • Paternot S, Coulonval K, Dumont JE, Roger PP 2003 Cyclic AMP-dependent phosphorylation of cyclin D3-bound CDK4 determines the passage through the cell cycle restriction point in thyroid epithelial cells. J Biol Chem 278:26533-26540
    • (2003) J Biol Chem , vol.278 , pp. 26533-26540
    • Paternot, S.1    Coulonval, K.2    Dumont, J.E.3    Roger, P.P.4
  • 62
    • 0034721067 scopus 로고    scopus 로고
    • Tsygankova OM, Kupperman E, Wen W, Meinkoth JL 2000 Cyclic AMP activates Ras. Oncogene 19:3609-3615
    • Tsygankova OM, Kupperman E, Wen W, Meinkoth JL 2000 Cyclic AMP activates Ras. Oncogene 19:3609-3615
  • 63
    • 0024814832 scopus 로고
    • Control of thyroperoxidase and thyroglobulin transcription by cAMP: Evidence for distinct regulatory mechanisms
    • Gerard CM, Lefort A, Christophe D, Libert F, Van Sande J, Dumont JE, Vassart G 1989 Control of thyroperoxidase and thyroglobulin transcription by cAMP: evidence for distinct regulatory mechanisms. Mol Endocrinol 3:2110-2118
    • (1989) Mol Endocrinol , vol.3 , pp. 2110-2118
    • Gerard, C.M.1    Lefort, A.2    Christophe, D.3    Libert, F.4    Van Sande, J.5    Dumont, J.E.6    Vassart, G.7
  • 64
    • 0025981328 scopus 로고
    • Control of the intracellular Ca(2+)-concentration and the inositol phosphate accumulation in dog thyrocyte primary culture: Evidence for different kinetics of Ca(2+)-phosphatidylinositol cascade activation and for involvement in the regulation of H2O2 production
    • Raspe E, Laurent E, Corvilain B, Verjans B, Erneux C, Dumont JE 1991 Control of the intracellular Ca(2+)-concentration and the inositol phosphate accumulation in dog thyrocyte primary culture: evidence for different kinetics of Ca(2+)-phosphatidylinositol cascade activation and for involvement in the regulation of H2O2 production. J Cell Physiol 146:242-250
    • (1991) J Cell Physiol , vol.146 , pp. 242-250
    • Raspe, E.1    Laurent, E.2    Corvilain, B.3    Verjans, B.4    Erneux, C.5    Dumont, J.E.6
  • 65
    • 0025924121 scopus 로고
    • The H2O2-generating system modulates protein iodination and the activity of the pentose phosphate pathway in dog thyroid
    • Corvilain B, Van Sande J, Laurent E, Dumont JE 1991 The H2O2-generating system modulates protein iodination and the activity of the pentose phosphate pathway in dog thyroid. Endocrinology 128:779-785
    • (1991) Endocrinology , vol.128 , pp. 779-785
    • Corvilain, B.1    Van Sande, J.2    Laurent, E.3    Dumont, J.E.4
  • 66
    • 33644688682 scopus 로고    scopus 로고
    • Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: Effects of silencing CREB gene expression on Akt activation
    • Misra UK, Pizzo SV 2005 Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation. J Biol Chem 280:38276-38289
    • (2005) J Biol Chem , vol.280 , pp. 38276-38289
    • Misra, U.K.1    Pizzo, S.V.2
  • 69
    • 33751522249 scopus 로고    scopus 로고
    • Differential utilization of cyclin D1 and cyclin D3 in the distinct mitogenic stimulations of human thyrocytes by growth factors and TSH
    • Paternot S, Dumont JE, Roger PP 2006 Differential utilization of cyclin D1 and cyclin D3 in the distinct mitogenic stimulations of human thyrocytes by growth factors and TSH. Mol Endocrinol 20:3279-3292
    • (2006) Mol Endocrinol , vol.20 , pp. 3279-3292
    • Paternot, S.1    Dumont, J.E.2    Roger, P.P.3
  • 70
    • 0027296639 scopus 로고
    • Inhibition of thyrotropin-stimulated DNA synthesis by microinjection of inhibitors of cellular Ras and cyclic AMP-dependent protein kinase
    • Kupperman E, Wen W, Meinkoth JL 1993 Inhibition of thyrotropin-stimulated DNA synthesis by microinjection of inhibitors of cellular Ras and cyclic AMP-dependent protein kinase. Mol Cell Biol 13:4477-4484
    • (1993) Mol Cell Biol , vol.13 , pp. 4477-4484
    • Kupperman, E.1    Wen, W.2    Meinkoth, J.L.3
  • 71
    • 10044253425 scopus 로고    scopus 로고
    • AKAP signalling complexes: Focal points in space and time
    • Wong W, Scott JD 2004 AKAP signalling complexes: focal points in space and time. Nat Rev Mol Cell Biol 5:959-970
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 959-970
    • Wong, W.1    Scott, J.D.2
  • 72
    • 33746381639 scopus 로고    scopus 로고
    • AKAP signaling complexes: Getting to the heart of the matter
    • McConnachie G, Langeberg LK, Scott JD 2006 AKAP signaling complexes: getting to the heart of the matter. Trends Mol Med 12:317-323
    • (2006) Trends Mol Med , vol.12 , pp. 317-323
    • McConnachie, G.1    Langeberg, L.K.2    Scott, J.D.3
  • 73
    • 33749077086 scopus 로고    scopus 로고
    • A RSK (y) relationship with promiscuous PKA
    • Houslay MD 2006 A RSK (y) relationship with promiscuous PKA. Sci STKE 2006:e32
    • (2006) Sci STKE 2006
    • Houslay, M.D.1
  • 74
    • 0030963439 scopus 로고    scopus 로고
    • cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway
    • Vossler MR, Yao H, York RD, Pan MG, Rim CS, Stork PJ 1997 cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway. Cell 89:73-82
    • (1997) Cell , vol.89 , pp. 73-82
    • Vossler, M.R.1    Yao, H.2    York, R.D.3    Pan, M.G.4    Rim, C.S.5    Stork, P.J.6
  • 76
    • 30044439907 scopus 로고    scopus 로고
    • Microtubule-associated protein 1B-light chain 1 enhances activation of Rap1 by exchange protein activated by cyclic AMP but not intracellular targeting
    • Borland G, Gupta M, Magiera MM, Rundell CJ, Fuld S, Yarwood SJ 2006 Microtubule-associated protein 1B-light chain 1 enhances activation of Rap1 by exchange protein activated by cyclic AMP but not intracellular targeting. Mol Pharmacol 69:374-384
    • (2006) Mol Pharmacol , vol.69 , pp. 374-384
    • Borland, G.1    Gupta, M.2    Magiera, M.M.3    Rundell, C.J.4    Fuld, S.5    Yarwood, S.J.6
  • 77
    • 0037450766 scopus 로고    scopus 로고
    • Mechanism of the spatio-temporal regulation of Ras and Rap1
    • Ohba Y, Kurokawa K, Matsuda M 2003 Mechanism of the spatio-temporal regulation of Ras and Rap1. EMBO J 22:859-869
    • (2003) EMBO J , vol.22 , pp. 859-869
    • Ohba, Y.1    Kurokawa, K.2    Matsuda, M.3
  • 79
    • 7244242394 scopus 로고    scopus 로고
    • The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the α3β1 integrin but not the α6β4 integrin
    • Enserink JM, Price LS, Methi T, Mahic M, Sonnenberg A, Bos JL, Tasken K 2004 The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the α3β1 integrin but not the α6β4 integrin. J Biol Chem 279:44889-44896
    • (2004) J Biol Chem , vol.279 , pp. 44889-44896
    • Enserink, J.M.1    Price, L.S.2    Methi, T.3    Mahic, M.4    Sonnenberg, A.5    Bos, J.L.6    Tasken, K.7
  • 80
    • 0024500871 scopus 로고
    • Thyrotropin but not epidermal growth factor down-regulates the isozyme I (PKa I) of cyclic AMP-dependent protein kinases in dog thyroid cells in primary cultures
    • Breton MF, Roger PP, Omri B, Dumont JE, Pavlovic Hournac M 1989 Thyrotropin but not epidermal growth factor down-regulates the isozyme I (PKa I) of cyclic AMP-dependent protein kinases in dog thyroid cells in primary cultures. Mol Cell Endocrinol 61:49-55
    • (1989) Mol Cell Endocrinol , vol.61 , pp. 49-55
    • Breton, M.F.1    Roger, P.P.2    Omri, B.3    Dumont, J.E.4    Pavlovic Hournac, M.5


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